JP2011172579A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2011172579A5 JP2011172579A5 JP2011083817A JP2011083817A JP2011172579A5 JP 2011172579 A5 JP2011172579 A5 JP 2011172579A5 JP 2011083817 A JP2011083817 A JP 2011083817A JP 2011083817 A JP2011083817 A JP 2011083817A JP 2011172579 A5 JP2011172579 A5 JP 2011172579A5
- Authority
- JP
- Japan
- Prior art keywords
- present
- dtdt
- seq
- consecutive
- nos
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108091028664 Ribonucleotide Proteins 0.000 claims 1
- 108091081021 Sense strand Proteins 0.000 claims 1
- 230000000692 anti-sense effect Effects 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 239000002336 ribonucleotide Substances 0.000 claims 1
- 125000002652 ribonucleotide group Chemical group 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54068704P | 2004-01-30 | 2004-01-30 | |
| US60/540,687 | 2004-01-30 | ||
| US64152205P | 2005-01-04 | 2005-01-04 | |
| US60/641,522 | 2005-01-04 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006550491A Division JP4755113B2 (ja) | 2004-01-30 | 2005-01-27 | 線維性状態およびその他の疾患の治療のための、オリゴリボヌクレオチドおよびその使用方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011172579A JP2011172579A (ja) | 2011-09-08 |
| JP2011172579A5 true JP2011172579A5 (OSRAM) | 2012-07-05 |
Family
ID=34830511
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006550491A Expired - Fee Related JP4755113B2 (ja) | 2004-01-30 | 2005-01-27 | 線維性状態およびその他の疾患の治療のための、オリゴリボヌクレオチドおよびその使用方法 |
| JP2011083817A Pending JP2011172579A (ja) | 2004-01-30 | 2011-04-05 | 線維性状態およびその他の疾患の治療のための、オリゴリボヌクレオチドおよびその使用方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006550491A Expired - Fee Related JP4755113B2 (ja) | 2004-01-30 | 2005-01-27 | 線維性状態およびその他の疾患の治療のための、オリゴリボヌクレオチドおよびその使用方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US20050197310A1 (OSRAM) |
| EP (2) | EP2330111A3 (OSRAM) |
| JP (2) | JP4755113B2 (OSRAM) |
| AT (1) | ATE491715T1 (OSRAM) |
| DE (1) | DE602005025347D1 (OSRAM) |
| WO (1) | WO2005072057A2 (OSRAM) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE602005025347D1 (de) * | 2004-01-30 | 2011-01-27 | Quark Pharmaceuticals Inc | Oligoribonukleotide und verfahren zu deren anwendung bei der behandlung von fibrotischen leiden und anderen krankheiten |
| US20100266574A1 (en) * | 2005-06-10 | 2010-10-21 | Orna Mor | Oligoribonucleotides and Methods of Use Thereof for Treatment of Fibrotic Conditions and Other Diseases |
| US8299040B2 (en) * | 2006-10-18 | 2012-10-30 | Board Of Regents, The University Of Texas System | Methods for treating cancer targeting transglutaminase |
| JP2010507387A (ja) * | 2006-10-25 | 2010-03-11 | クアーク・ファーマスーティカルス、インコーポレイテッド | 新規のsiRNAおよびその使用方法 |
| WO2008152636A2 (en) * | 2007-06-15 | 2008-12-18 | Quark Pharmaceuticals, Inc. | Compositions and methods for inhibiting nadph oxidase expression |
| US9051568B2 (en) | 2008-04-25 | 2015-06-09 | Rutgers, The State University Of New Jersey | Anti-sense microrna expression vectors |
| WO2012108841A1 (en) * | 2011-02-09 | 2012-08-16 | Singapore Health Services Pte. Ltd. | Transglutaminase-2 inhibitors and uses thereof |
| EP3533873A1 (en) | 2011-09-14 | 2019-09-04 | Translate Bio MA, Inc. | Multimeric oligonucleotide compounds |
| US9234048B2 (en) | 2012-01-18 | 2016-01-12 | Wisconsin Alumni Research Foundation | Boronate-mediated delivery of molecules into cells |
| US9732101B2 (en) | 2012-01-18 | 2017-08-15 | Wisconsin Alumni Research Foundation | Bioreversible boronates for delivery of molecules into cells |
| US9340784B2 (en) | 2012-03-19 | 2016-05-17 | Ionis Pharmaceuticals, Inc. | Methods and compositions for modulating alpha-1-antitrypsin expression |
| US20150247141A1 (en) | 2012-09-14 | 2015-09-03 | Rana Therapeutics, Inc. | Multimeric oligonucleotide compounds |
| US10155948B2 (en) | 2016-05-12 | 2018-12-18 | Kangwon National University University-Industry Cooperation Foundation and | Pharmaceutical composition for preventing or treating diabetic complications and screening method for preventive or therapeutic agent for diabetic complications |
| KR101881662B1 (ko) * | 2016-05-12 | 2018-07-26 | 강원대학교산학협력단 | 당뇨성 합병증 예방 및 치료용 약제학적 조성물 및 당뇨성 합병증 예방 또는 치료제 스크리닝 방법 |
| CN110177544A (zh) | 2016-11-29 | 2019-08-27 | 普尔泰克健康有限公司 | 用于递送治疗剂的外泌体 |
| IT201800009133A1 (it) * | 2018-10-03 | 2020-04-03 | Università Cattolica del Sacro Cuore | Identificazione di biomarcatori molecolari predittivi di risposta al trattamento radiochemoterapico nel carcinoma della cervice |
| EP4507702A2 (en) * | 2022-04-14 | 2025-02-19 | ARO Biotherapeutics Company | Fn3 domain-sirna conjugates with enzyme replacement therapy |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4475196A (en) | 1981-03-06 | 1984-10-02 | Zor Clair G | Instrument for locating faults in aircraft passenger reading light and attendant call control system |
| US4447233A (en) | 1981-04-10 | 1984-05-08 | Parker-Hannifin Corporation | Medication infusion pump |
| US4439196A (en) | 1982-03-18 | 1984-03-27 | Merck & Co., Inc. | Osmotic drug delivery system |
| US4447224A (en) | 1982-09-20 | 1984-05-08 | Infusaid Corporation | Variable flow implantable infusion apparatus |
| US4487603A (en) | 1982-11-26 | 1984-12-11 | Cordis Corporation | Implantable microinfusion pump system |
| US4486194A (en) | 1983-06-08 | 1984-12-04 | James Ferrara | Therapeutic device for administering medicaments through the skin |
| US4666828A (en) | 1984-08-15 | 1987-05-19 | The General Hospital Corporation | Test for Huntington's disease |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4801531A (en) | 1985-04-17 | 1989-01-31 | Biotechnology Research Partners, Ltd. | Apo AI/CIII genomic polymorphisms predictive of atherosclerosis |
| US4959217A (en) | 1986-05-22 | 1990-09-25 | Syntex (U.S.A.) Inc. | Delayed/sustained release of macromolecules |
| US4925678A (en) | 1987-04-01 | 1990-05-15 | Ranney David F | Endothelial envelopment drug carriers |
| US5080646A (en) | 1988-10-03 | 1992-01-14 | Alza Corporation | Membrane for electrotransport transdermal drug delivery |
| US5272057A (en) | 1988-10-14 | 1993-12-21 | Georgetown University | Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase |
| US5270030A (en) | 1988-12-29 | 1993-12-14 | Bio-Technology General Corp. | Fibrin binding domain polypeptide and method of producing |
| US5021440A (en) | 1989-07-31 | 1991-06-04 | Merck & Co., Inc. | Imidazole compounds and their use as transglutaminase inhibitors |
| US5098707A (en) | 1989-07-31 | 1992-03-24 | Merck & Co., Inc. | Imidazole compounds and their use as transglutaminase inhibitors |
| US4968713A (en) | 1989-07-31 | 1990-11-06 | Merck & Co., Inc. | Certain imidazole compounds as transglutaminase inhibitors |
| US5192659A (en) | 1989-08-25 | 1993-03-09 | Genetype Ag | Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes |
| US5399676A (en) | 1989-10-23 | 1995-03-21 | Gilead Sciences | Oligonucleotides with inverted polarity |
| US5167616A (en) | 1989-12-14 | 1992-12-01 | Alza Corporation | Iontophoretic delivery method |
| US5587361A (en) | 1991-10-15 | 1996-12-24 | Isis Pharmaceuticals, Inc. | Oligonucleotides having phosphorothioate linkages of high chiral purity |
| US5489677A (en) | 1990-07-27 | 1996-02-06 | Isis Pharmaceuticals, Inc. | Oligonucleoside linkages containing adjacent oxygen and nitrogen atoms |
| AU662298B2 (en) | 1990-09-20 | 1995-08-31 | Gilead Sciences, Inc. | Modified internucleoside linkages |
| US5225182A (en) | 1991-10-31 | 1993-07-06 | Sharma Yash P | Vectored drug delivery system using a cephaloplastin linking agent and a methed of using the system |
| EP0642589A4 (en) | 1992-05-11 | 1997-05-21 | Ribozyme Pharm Inc | METHOD AND REAGENT TO INHIBIT VIRAL REPLICATION. |
| US5898031A (en) | 1996-06-06 | 1999-04-27 | Isis Pharmaceuticals, Inc. | Oligoribonucleotides for cleaving RNA |
| AU6620596A (en) * | 1996-07-25 | 1998-02-20 | Victoria University Of Manchester, The | Use of transglutaminase modulators to promote wound healing |
| US6506559B1 (en) * | 1997-12-23 | 2003-01-14 | Carnegie Institute Of Washington | Genetic inhibition by double-stranded RNA |
| US6242589B1 (en) | 1998-07-14 | 2001-06-05 | Isis Pharmaceuticals, Inc. | Phosphorothioate oligonucleotides having modified internucleoside linkages |
| US6277967B1 (en) | 1998-07-14 | 2001-08-21 | Isis Pharmaceuticals, Inc. | Carbohydrate or 2′-modified oligonucleotides having alternating internucleoside linkages |
| AU771579B2 (en) | 1998-10-26 | 2004-03-25 | Avi Biopharma, Inc. | p53 antisense agent and method |
| US6773916B1 (en) * | 1999-01-05 | 2004-08-10 | The Flinders University Of South Australia | Agents and methods for treatment and diagnosis of ocular disorders |
| DE19956568A1 (de) | 1999-01-30 | 2000-08-17 | Roland Kreutzer | Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens |
| GB9927444D0 (en) | 1999-11-19 | 2000-01-19 | Cancer Res Campaign Tech | Inhibiting gene expression |
| WO2002081628A2 (en) * | 2001-04-05 | 2002-10-17 | Ribozyme Pharmaceuticals, Incorporated | Modulation of gene expression associated with inflammation proliferation and neurite outgrowth, using nucleic acid based technologies |
| DK2796553T3 (da) * | 2000-03-30 | 2019-09-30 | Whitehead Inst Biomedical Res | Rna-sekvensspecifikke formidlere af rna-interferens |
| CZ302719B6 (cs) * | 2000-12-01 | 2011-09-21 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Izolovaná molekula dvouretezcové RNA, zpusob její výroby a její použití |
| WO2002085308A2 (en) | 2001-04-24 | 2002-10-31 | Epigenesis Pharmaceuticals, Inc. | Antisense and anti-inflammatory based compositions to treat respiratory disorders |
| WO2002085309A2 (en) * | 2001-04-24 | 2002-10-31 | Epigenesis Pharmaceuticals, Inc. | Composition, formulations & kits for treatment of respiratory & lung disease with anti-sense oligonucleotides & a bronchodilating agent |
| US20040019001A1 (en) | 2002-02-20 | 2004-01-29 | Mcswiggen James A. | RNA interference mediated inhibition of protein typrosine phosphatase-1B (PTP-1B) gene expression using short interfering RNA |
| WO2003070197A2 (en) * | 2002-02-20 | 2003-08-28 | Sirna Therapeutics, Inc. | RNA INTERFERENCE MEDIATED INHIBITION OF TGF-BETA AND TGF-BETA RECEPTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) |
| US20040063654A1 (en) | 2001-11-02 | 2004-04-01 | Davis Mark E. | Methods and compositions for therapeutic use of RNA interference |
| EP1432724A4 (en) | 2002-02-20 | 2006-02-01 | Sirna Therapeutics Inc | INTERFERENCE MEDIATION INHIBITION OF GENE RNA FROM MAP KINASE |
| ITMI20021527A1 (it) | 2002-07-11 | 2004-01-12 | Consiglio Nazionale Ricerche | Anticorpi anti componente c5 del complemento e loro uso |
| US7148342B2 (en) | 2002-07-24 | 2006-12-12 | The Trustees Of The University Of Pennyslvania | Compositions and methods for sirna inhibition of angiogenesis |
| DK1527176T4 (en) * | 2002-08-05 | 2017-07-03 | Silence Therapeutics Gmbh | ADDITIONAL NEW FORMS OF INTERFERRING RNA MOLECULES |
| WO2004039955A2 (en) * | 2002-10-29 | 2004-05-13 | Rigel Pharmaceuticals, Inc. | Modulators of angiogenesis and tumorigenesis |
| WO2004113496A2 (en) * | 2003-06-20 | 2004-12-29 | Isis Pharmaceuticals, Inc. | Double stranded compositions comprising a 3’-endo modified strand for use in gene modulation |
| DE602005025347D1 (de) | 2004-01-30 | 2011-01-27 | Quark Pharmaceuticals Inc | Oligoribonukleotide und verfahren zu deren anwendung bei der behandlung von fibrotischen leiden und anderen krankheiten |
-
2005
- 2005-01-27 DE DE602005025347T patent/DE602005025347D1/de not_active Expired - Lifetime
- 2005-01-27 AT AT05703145T patent/ATE491715T1/de not_active IP Right Cessation
- 2005-01-27 US US11/045,780 patent/US20050197310A1/en not_active Abandoned
- 2005-01-27 WO PCT/IL2005/000102 patent/WO2005072057A2/en not_active Ceased
- 2005-01-27 EP EP10179637A patent/EP2330111A3/en not_active Withdrawn
- 2005-01-27 JP JP2006550491A patent/JP4755113B2/ja not_active Expired - Fee Related
- 2005-01-27 EP EP05703145A patent/EP1758998B1/en not_active Expired - Lifetime
-
2008
- 2008-02-28 US US12/072,941 patent/US7939652B2/en active Active
-
2011
- 2011-04-05 JP JP2011083817A patent/JP2011172579A/ja active Pending
- 2011-04-22 US US13/092,501 patent/US8198258B2/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2011172579A5 (OSRAM) | ||
| JP2013539454A5 (OSRAM) | ||
| JP2011155981A5 (OSRAM) | ||
| JP2012505657A5 (OSRAM) | ||
| JP2011168603A5 (OSRAM) | ||
| CY1115253T1 (el) | Κρυσταλλικες μορφες ενος παραγωγου 2-θειαζολυλο-4-κινολινυλ-οξυ-ομαδας, ενος ισχυρου αναστολεα του ηcv | |
| JP2011136981A5 (OSRAM) | ||
| WO2011139699A3 (en) | 5' modified nucleosides and oligomeric compounds prepared therefrom | |
| IL264288B (en) | Methods and compositions for modulating apolipoprotein(a) expression | |
| IL206462A0 (en) | Genetically modified attenuated vesicular stomatitis virus, compositions and methods of use thereof | |
| JP2010088434A5 (OSRAM) | ||
| JP2013512915A5 (OSRAM) | ||
| JP2012034696A5 (OSRAM) | ||
| JP2015501155A5 (OSRAM) | ||
| DK2944646T3 (da) | Oligonukleotidanaloger, der inkorporerer 5-aza-cytosin | |
| MY160722A (en) | Preparing high order hydridosilane compounds | |
| JP2015502963A5 (OSRAM) | ||
| JP2014521310A5 (OSRAM) | ||
| JP2013504665A5 (OSRAM) | ||
| JP2011148943A5 (OSRAM) | ||
| JP2013503110A5 (OSRAM) | ||
| JP2015513535A5 (OSRAM) | ||
| JP2015128433A5 (OSRAM) | ||
| JP2012517503A5 (OSRAM) | ||
| BRPI0922645A2 (pt) | "arilamidas tiadiazol substituídas". |