JP2011046748A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2011046748A5 JP2011046748A5 JP2010274133A JP2010274133A JP2011046748A5 JP 2011046748 A5 JP2011046748 A5 JP 2011046748A5 JP 2010274133 A JP2010274133 A JP 2010274133A JP 2010274133 A JP2010274133 A JP 2010274133A JP 2011046748 A5 JP2011046748 A5 JP 2011046748A5
- Authority
- JP
- Japan
- Prior art keywords
- tween
- polyoxyethylene sorbitan
- virion
- pharmaceutical composition
- surfactant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims 24
- 238000000034 method Methods 0.000 claims 23
- 210000002845 virion Anatomy 0.000 claims 23
- 239000008194 pharmaceutical composition Substances 0.000 claims 17
- 229920001213 Polysorbate 20 Polymers 0.000 claims 14
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 claims 14
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 claims 14
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 claims 14
- 229920000053 polysorbate 80 Polymers 0.000 claims 14
- 239000004094 surface-active agent Substances 0.000 claims 12
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims 11
- 239000000600 sorbitol Substances 0.000 claims 11
- 150000001298 alcohols Chemical class 0.000 claims 9
- 239000002202 Polyethylene glycol Substances 0.000 claims 8
- 229920001223 polyethylene glycol Polymers 0.000 claims 8
- -1 sorbitan ester Chemical class 0.000 claims 8
- 239000000203 mixture Substances 0.000 claims 7
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 claims 7
- 229920001214 Polysorbate 60 Polymers 0.000 claims 6
- 230000000087 stabilizing effect Effects 0.000 claims 6
- 150000005846 sugar alcohols Polymers 0.000 claims 6
- 230000000694 effects Effects 0.000 claims 4
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 3
- 239000004147 Sorbitan trioleate Substances 0.000 claims 3
- PRXRUNOAOLTIEF-ADSICKODSA-N Sorbitan trioleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](OC(=O)CCCCCCC\C=C/CCCCCCCC)[C@H]1OC[C@H](O)[C@H]1OC(=O)CCCCCCC\C=C/CCCCCCCC PRXRUNOAOLTIEF-ADSICKODSA-N 0.000 claims 3
- 239000000249 polyoxyethylene sorbitan monopalmitate Substances 0.000 claims 3
- 235000010483 polyoxyethylene sorbitan monopalmitate Nutrition 0.000 claims 3
- 239000001816 polyoxyethylene sorbitan tristearate Substances 0.000 claims 3
- 235000010988 polyoxyethylene sorbitan tristearate Nutrition 0.000 claims 3
- 235000019337 sorbitan trioleate Nutrition 0.000 claims 3
- 229960000391 sorbitan trioleate Drugs 0.000 claims 3
- 239000002253 acid Substances 0.000 claims 2
- 150000002148 esters Chemical class 0.000 claims 2
- 230000008014 freezing Effects 0.000 claims 2
- 238000007710 freezing Methods 0.000 claims 2
- 239000011521 glass Substances 0.000 claims 2
- 239000001818 polyoxyethylene sorbitan monostearate Substances 0.000 claims 2
- 235000010989 polyoxyethylene sorbitan monostearate Nutrition 0.000 claims 2
- 238000002360 preparation method Methods 0.000 claims 2
- 238000010257 thawing Methods 0.000 claims 2
- 241000702421 Dependoparvovirus Species 0.000 claims 1
- HVUMOYIDDBPOLL-XWVZOOPGSA-N Sorbitan monostearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O HVUMOYIDDBPOLL-XWVZOOPGSA-N 0.000 claims 1
- 239000002736 nonionic surfactant Substances 0.000 claims 1
- 229920000136 polysorbate Polymers 0.000 claims 1
- 239000001587 sorbitan monostearate Substances 0.000 claims 1
- 235000011076 sorbitan monostearate Nutrition 0.000 claims 1
- 229940035048 sorbitan monostearate Drugs 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11068998P | 1998-12-03 | 1998-12-03 | |
| US60/110,689 | 1998-12-03 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000584922A Division JP2002531418A (ja) | 1998-12-03 | 1999-12-02 | アデノ随伴ウイルスの薬学処方物における使用のための賦形剤、およびそれにより構成される薬学処方物 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014000095A Division JP2014058578A (ja) | 1998-12-03 | 2014-01-06 | アデノ随伴ウイルスの薬学処方物における使用のための賦形剤、およびそれにより構成される薬学処方物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011046748A JP2011046748A (ja) | 2011-03-10 |
| JP2011046748A5 true JP2011046748A5 (https=) | 2012-05-24 |
| JP5663285B2 JP5663285B2 (ja) | 2015-02-04 |
Family
ID=22334360
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000584922A Pending JP2002531418A (ja) | 1998-12-03 | 1999-12-02 | アデノ随伴ウイルスの薬学処方物における使用のための賦形剤、およびそれにより構成される薬学処方物 |
| JP2010274133A Expired - Lifetime JP5663285B2 (ja) | 1998-12-03 | 2010-12-08 | アデノ随伴ウイルスの薬学処方物における使用のための賦形剤、およびそれにより構成される薬学処方物 |
| JP2014000095A Withdrawn JP2014058578A (ja) | 1998-12-03 | 2014-01-06 | アデノ随伴ウイルスの薬学処方物における使用のための賦形剤、およびそれにより構成される薬学処方物 |
| JP2015241786A Withdrawn JP2016040330A (ja) | 1998-12-03 | 2015-12-11 | アデノ随伴ウイルスの薬学処方物における使用のための賦形剤、およびそれにより構成される薬学処方物 |
| JP2017157878A Pending JP2017206556A (ja) | 1998-12-03 | 2017-08-18 | アデノ随伴ウイルスの薬学処方物における使用のための賦形剤、およびそれにより構成される薬学処方物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000584922A Pending JP2002531418A (ja) | 1998-12-03 | 1999-12-02 | アデノ随伴ウイルスの薬学処方物における使用のための賦形剤、およびそれにより構成される薬学処方物 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014000095A Withdrawn JP2014058578A (ja) | 1998-12-03 | 2014-01-06 | アデノ随伴ウイルスの薬学処方物における使用のための賦形剤、およびそれにより構成される薬学処方物 |
| JP2015241786A Withdrawn JP2016040330A (ja) | 1998-12-03 | 2015-12-11 | アデノ随伴ウイルスの薬学処方物における使用のための賦形剤、およびそれにより構成される薬学処方物 |
| JP2017157878A Pending JP2017206556A (ja) | 1998-12-03 | 2017-08-18 | アデノ随伴ウイルスの薬学処方物における使用のための賦形剤、およびそれにより構成される薬学処方物 |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1144009B1 (https=) |
| JP (5) | JP2002531418A (https=) |
| AT (1) | ATE226449T1 (https=) |
| AU (2) | AU773834B2 (https=) |
| CA (1) | CA2353417C (https=) |
| DE (1) | DE69903666T2 (https=) |
| ES (1) | ES2185417T3 (https=) |
| PT (1) | PT1144009E (https=) |
| WO (1) | WO2000032233A2 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002080977A1 (en) * | 2001-04-04 | 2002-10-17 | Delsitech Oy | Biodegradable carrier and method for preparation thereof |
| EP1453536A4 (en) | 2001-12-12 | 2009-08-26 | Mayne Pharma Int Pty Ltd | COMPOSITION FOR PRESERVING VIRUSES |
| US7261882B2 (en) | 2003-06-23 | 2007-08-28 | Reagents Of The University Of Colorado | Methods for treating neuropathic pain by administering IL-10 polypeptides |
| LT2816118T (lt) | 2005-05-31 | 2018-12-10 | The Regents Of The University Of Colorado, A Body Corporate | Genų pristatymo būdai |
| CA2742817A1 (en) * | 2008-11-20 | 2010-05-27 | Biogen Idec Ma Inc. | Arginine inactivation of viruses |
| JP6348064B2 (ja) | 2011-11-22 | 2018-06-27 | ザ チルドレンズ ホスピタル オブ フィラデルフィア | 効率の高いトランスジーン送達のためのウイルスベクター |
| EP3436078B1 (en) | 2016-03-31 | 2021-10-27 | University of Cincinnati | Methods and compositions for the treatment of als |
| JP2019530737A (ja) | 2016-08-23 | 2019-10-24 | アコーオス インコーポレイテッド | ヒト対象において非加齢性聴力障害を治療するための組成物および方法 |
| EP3626821A4 (en) | 2017-05-18 | 2021-03-03 | Kyoto University | COMPOSITION FOR THE PREVENTION OR TREATMENT OF SPINOCEREBEL ATAXIA TYPE 36 |
| EP3720500A4 (en) * | 2017-12-05 | 2021-08-25 | Applied Genetic Technologies Corporation | FORMULATION OPTIMIZATION FOR VIRAL PARTICLES |
| US20220143115A1 (en) * | 2019-04-19 | 2022-05-12 | Regenxbio Inc. | Adeno-Associated Virus Vector Formulations and Methods |
| US20220325250A1 (en) | 2019-08-14 | 2022-10-13 | Leukocare Ag | Method for obtaining efficient compositions comprising viral vectors for vaccination or gene therapy |
| JP7807380B2 (ja) | 2020-02-21 | 2026-01-27 | アコーオス インコーポレイテッド | ヒト対象において非加齢関連聴力障害を処置するための組成物および方法 |
| US20240066146A1 (en) * | 2020-12-18 | 2024-02-29 | Sangamo Therapeutics, Inc. | Improved pharmaceutical compositions containing adeno-associated viral vector |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5616487A (en) * | 1994-09-15 | 1997-04-01 | Aastrom Biosciences, Inc. | Stabilized retrovirus compositions |
| FR2751343B1 (fr) * | 1996-07-16 | 1998-12-18 | Transgene Sa | Procede de conservation de virus recombinants infectieux, suspension aqueuse virale et utilisation comme medicament |
| US6521225B1 (en) * | 1996-09-06 | 2003-02-18 | Chiron Corporation | AAV vectors |
-
1999
- 1999-12-02 AT AT99964038T patent/ATE226449T1/de not_active IP Right Cessation
- 1999-12-02 CA CA002353417A patent/CA2353417C/en not_active Expired - Lifetime
- 1999-12-02 EP EP99964038A patent/EP1144009B1/en not_active Expired - Lifetime
- 1999-12-02 JP JP2000584922A patent/JP2002531418A/ja active Pending
- 1999-12-02 DE DE69903666T patent/DE69903666T2/de not_active Expired - Lifetime
- 1999-12-02 AU AU20361/00A patent/AU773834B2/en not_active Expired
- 1999-12-02 WO PCT/US1999/028460 patent/WO2000032233A2/en not_active Ceased
- 1999-12-02 ES ES99964038T patent/ES2185417T3/es not_active Expired - Lifetime
- 1999-12-02 PT PT99964038T patent/PT1144009E/pt unknown
-
2004
- 2004-08-27 AU AU2004205308A patent/AU2004205308A1/en not_active Abandoned
-
2010
- 2010-12-08 JP JP2010274133A patent/JP5663285B2/ja not_active Expired - Lifetime
-
2014
- 2014-01-06 JP JP2014000095A patent/JP2014058578A/ja not_active Withdrawn
-
2015
- 2015-12-11 JP JP2015241786A patent/JP2016040330A/ja not_active Withdrawn
-
2017
- 2017-08-18 JP JP2017157878A patent/JP2017206556A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2011046748A5 (https=) | ||
| JP2013166818A5 (https=) | ||
| CN103028275B (zh) | 一种固体有机硅消泡剂的制备方法 | |
| JP2012523410A5 (https=) | ||
| JP2015534601A5 (https=) | ||
| JP2013545846A5 (https=) | ||
| WO2010107739A3 (en) | Methods and compositions of treating a flaviviridae family viral infection | |
| JP2016510019A5 (https=) | ||
| JP2013537874A5 (https=) | ||
| BRPI0511764B8 (pt) | método de prevenção de agregação de vírions de vírus adeno-associado recombinante (raav) em uma preparação purificada de virions raav | |
| JP2012528047A5 (https=) | ||
| JP2014520806A5 (https=) | ||
| WO2012075376A3 (en) | Lyophilized viral formulations | |
| JP2008290071A5 (https=) | ||
| JP2014210359A5 (https=) | ||
| IN2014MN01548A (https=) | ||
| WO2010097307A3 (en) | Novel zirconia ceria compositions | |
| WO2011118858A3 (en) | Treatment agent for use in lignocellulose material | |
| RU2016129183A (ru) | Порошковая композиция полиариленэфиркетонкетонов, позволяющая достичь отличного баланса между сыпучестью и слипанием, подходящая для лазерного спекания | |
| JP2013528838A5 (https=) | ||
| RU2016120766A (ru) | Синтез и применение композиций металлосодержащих полиэдрических олигомерных силсесквиоксановых катализаторов | |
| MX2015011762A (es) | Polieteres activos de cadena larga catalizados por bases preparados a partir de iniciadores catalizados por dmc de cadena corta. | |
| JP2013500381A5 (https=) | ||
| JP2012057155A5 (https=) | ||
| AR083521A1 (es) | Mejoras relativas a acondicionadores de telas |