JP2011012063A - 3−シアノキノリン錠剤製剤およびそれらの用途 - Google Patents
3−シアノキノリン錠剤製剤およびそれらの用途 Download PDFInfo
- Publication number
- JP2011012063A JP2011012063A JP2010151063A JP2010151063A JP2011012063A JP 2011012063 A JP2011012063 A JP 2011012063A JP 2010151063 A JP2010151063 A JP 2010151063A JP 2010151063 A JP2010151063 A JP 2010151063A JP 2011012063 A JP2011012063 A JP 2011012063A
- Authority
- JP
- Japan
- Prior art keywords
- weight
- composition
- weight percent
- methoxy
- ski
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22253709P | 2009-07-02 | 2009-07-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
JP2011012063A true JP2011012063A (ja) | 2011-01-20 |
Family
ID=42732381
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2010151063A Withdrawn JP2011012063A (ja) | 2009-07-02 | 2010-07-01 | 3−シアノキノリン錠剤製剤およびそれらの用途 |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP2448563A2 (es) |
JP (1) | JP2011012063A (es) |
KR (1) | KR20120046216A (es) |
CN (1) | CN102470109A (es) |
AR (1) | AR077546A1 (es) |
AU (1) | AU2010266342A1 (es) |
BR (1) | BRPI1015941A2 (es) |
CA (1) | CA2766067A1 (es) |
IL (1) | IL217298A0 (es) |
MX (1) | MX2012000048A (es) |
RU (1) | RU2011152105A (es) |
SG (1) | SG177309A1 (es) |
TW (1) | TW201113050A (es) |
WO (1) | WO2011002857A2 (es) |
ZA (1) | ZA201200366B (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102886045A (zh) | 2005-02-03 | 2013-01-23 | 综合医院公司 | 治疗吉非替尼耐药性癌症的方法 |
AR057854A1 (es) | 2005-11-04 | 2007-12-19 | Wyeth Corp | Combinaciones antineoplasicas con inhibidor de mtor, herceptina y/o hki-272 (e)-n-{4-[3-cloro-4-(2-piridinilmetoxi) anilino]-3-ciano-7-etoxi-6-quinolinil}-4-(dimetilamino)-2-butenamida |
US8022216B2 (en) | 2007-10-17 | 2011-09-20 | Wyeth Llc | Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof |
EP2915532B1 (en) | 2008-06-17 | 2016-10-19 | Wyeth LLC | Antineoplastic combinations containing hki-272 and vinorelbine |
JP5681108B2 (ja) | 2008-08-04 | 2015-03-04 | ワイス・エルエルシー | 4−アニリノ−3−シアノキノリンとカペシタビンの抗新生物薬の組合せ |
RU2011139363A (ru) | 2009-04-06 | 2013-05-20 | ВАЙЕТ ЭлЭлСи | Схема лечения рака молочной железы с использованием нератиниба |
CA2780332C (en) | 2009-11-09 | 2018-01-30 | Wyeth Llc | Coated drug spheroids and uses thereof for eliminating or reducing conditions such as emesis and diarrhea |
DK2498756T4 (da) | 2009-11-09 | 2023-03-20 | Wyeth Llc | Tabletformuleringer af neratinibmaleat |
CN104447541A (zh) * | 2013-09-16 | 2015-03-25 | 天津市汉康医药生物技术有限公司 | 博舒替尼化合物 |
CN105384686B (zh) * | 2014-09-04 | 2019-07-26 | 连云港润众制药有限公司 | 一种博舒替尼结晶方法 |
US20190060325A1 (en) * | 2016-04-08 | 2019-02-28 | Shionogi & Co., Ltd. | Stabilized solid dosage form |
KR102297116B1 (ko) | 2017-03-31 | 2021-09-01 | 닛세이 에이. 에스. 비 기카이 가부시키가이샤 | 수지제 용기 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6297258B1 (en) | 1998-09-29 | 2001-10-02 | American Cyanamid Company | Substituted 3-cyanoquinolines |
MXPA04008307A (es) * | 2002-02-26 | 2004-11-26 | Astrazeneca Ab | Formulacion farmaceutica de iressa que comprende un derivado de celulosa soluble en agua. |
MXPA06001590A (es) | 2003-08-19 | 2006-05-19 | Wyeth Corp | Proceso para la preparacion de 4-amino-3-quinolincarbonitrilos. |
JP4834553B2 (ja) * | 2004-09-17 | 2011-12-14 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 医薬組成物 |
WO2007005462A1 (en) * | 2005-07-01 | 2007-01-11 | Wyeth | Crystalline forms of 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarb-onitrile and methods of preparing the same |
WO2008053295A2 (en) * | 2006-10-30 | 2008-05-08 | Wockhardt Research Centre | Pharmaceutical compositions of benzoquinolizine-2-carboxylic acid |
CN101224185A (zh) * | 2007-12-11 | 2008-07-23 | 山东蓝金生物工程有限公司 | 一种治疗实体肿瘤的伯舒替尼缓释植入剂 |
-
2010
- 2010-06-30 AU AU2010266342A patent/AU2010266342A1/en not_active Abandoned
- 2010-06-30 SG SG2011094950A patent/SG177309A1/en unknown
- 2010-06-30 WO PCT/US2010/040555 patent/WO2011002857A2/en active Application Filing
- 2010-06-30 CA CA2766067A patent/CA2766067A1/en not_active Abandoned
- 2010-06-30 RU RU2011152105/15A patent/RU2011152105A/ru unknown
- 2010-06-30 KR KR1020127002851A patent/KR20120046216A/ko not_active Application Discontinuation
- 2010-06-30 MX MX2012000048A patent/MX2012000048A/es not_active Application Discontinuation
- 2010-06-30 BR BRPI1015941A patent/BRPI1015941A2/pt not_active Application Discontinuation
- 2010-06-30 EP EP10732568A patent/EP2448563A2/en not_active Withdrawn
- 2010-06-30 CN CN2010800294791A patent/CN102470109A/zh active Pending
- 2010-07-01 TW TW099121740A patent/TW201113050A/zh unknown
- 2010-07-01 JP JP2010151063A patent/JP2011012063A/ja not_active Withdrawn
- 2010-07-02 AR ARP100102373A patent/AR077546A1/es not_active Application Discontinuation
-
2011
- 2011-12-29 IL IL217298A patent/IL217298A0/en unknown
-
2012
- 2012-01-17 ZA ZA2012/00366A patent/ZA201200366B/en unknown
Also Published As
Publication number | Publication date |
---|---|
SG177309A1 (en) | 2012-02-28 |
AU2010266342A1 (en) | 2012-01-19 |
EP2448563A2 (en) | 2012-05-09 |
CA2766067A1 (en) | 2011-01-06 |
CN102470109A (zh) | 2012-05-23 |
RU2011152105A (ru) | 2013-08-10 |
TW201113050A (en) | 2011-04-16 |
KR20120046216A (ko) | 2012-05-09 |
ZA201200366B (en) | 2012-10-31 |
BRPI1015941A2 (pt) | 2016-04-19 |
IL217298A0 (en) | 2012-02-29 |
AR077546A1 (es) | 2011-09-07 |
MX2012000048A (es) | 2012-01-27 |
WO2011002857A2 (en) | 2011-01-06 |
WO2011002857A3 (en) | 2011-03-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP2011012063A (ja) | 3−シアノキノリン錠剤製剤およびそれらの用途 | |
JP5835883B2 (ja) | 被覆錠剤製剤 | |
JP2021138778A (ja) | アンチセンス組成物およびその作製および使用 | |
JP5982020B2 (ja) | 嘔吐および下痢などの状態を解消または軽減するためのコーティングされた薬物球状体およびその用途 | |
CN1864663A (zh) | 5,7,14-三氮杂四环[10.3.1.0(2,11).0(4,9)]-十六碳-2(11)3,5,7,9-五烯的药物组合物 | |
KR20100099113A (ko) | 만니톨 및/또는 미세결정질 셀룰로스를 포함하는 지보텐탄 조성물 | |
JP2023065568A (ja) | 異常な細胞成長を処置するための組成物および方法 | |
WO2007141806A1 (en) | Pharmaceutical formulations comprising oxcarbazepine and methods thereof | |
US8741344B1 (en) | Dispersible tablet | |
DK177906B1 (en) | Dispersible tablet | |
WO2007033522A1 (fr) | Formulation de gélule contenant de la moxifloxacine et son procédé de préparation |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A300 | Application deemed to be withdrawn because no request for examination was validly filed |
Free format text: JAPANESE INTERMEDIATE CODE: A300 Effective date: 20130903 |