ZA201200366B - 3-cyanoquinoline tablet formulations and uses thereof - Google Patents

3-cyanoquinoline tablet formulations and uses thereof

Info

Publication number
ZA201200366B
ZA201200366B ZA2012/00366A ZA201200366A ZA201200366B ZA 201200366 B ZA201200366 B ZA 201200366B ZA 2012/00366 A ZA2012/00366 A ZA 2012/00366A ZA 201200366 A ZA201200366 A ZA 201200366A ZA 201200366 B ZA201200366 B ZA 201200366B
Authority
ZA
South Africa
Prior art keywords
cyanoquinoline
tablet formulations
formulations
tablet
cyanoquinoline tablet
Prior art date
Application number
ZA2012/00366A
Inventor
Goldi Kaul
Arwinder Nagi
Ramarao Chatlapalli
Krishnendu Ghosh
Original Assignee
Wyeth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Llc filed Critical Wyeth Llc
Publication of ZA201200366B publication Critical patent/ZA201200366B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
ZA2012/00366A 2009-07-02 2012-01-17 3-cyanoquinoline tablet formulations and uses thereof ZA201200366B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22253709P 2009-07-02 2009-07-02
PCT/US2010/040555 WO2011002857A2 (en) 2009-07-02 2010-06-30 3-cyanoquinoline tablet formulations and uses thereof

Publications (1)

Publication Number Publication Date
ZA201200366B true ZA201200366B (en) 2012-10-31

Family

ID=42732381

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2012/00366A ZA201200366B (en) 2009-07-02 2012-01-17 3-cyanoquinoline tablet formulations and uses thereof

Country Status (15)

Country Link
EP (1) EP2448563A2 (en)
JP (1) JP2011012063A (en)
KR (1) KR20120046216A (en)
CN (1) CN102470109A (en)
AR (1) AR077546A1 (en)
AU (1) AU2010266342A1 (en)
BR (1) BRPI1015941A2 (en)
CA (1) CA2766067A1 (en)
IL (1) IL217298A0 (en)
MX (1) MX2012000048A (en)
RU (1) RU2011152105A (en)
SG (1) SG177309A1 (en)
TW (1) TW201113050A (en)
WO (1) WO2011002857A2 (en)
ZA (1) ZA201200366B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113952338A (en) 2005-02-03 2022-01-21 综合医院公司 Methods of treating gefitinib resistant cancers
CA2626326C (en) 2005-11-04 2021-02-16 Wyeth Antineoplastic combinations with mtor inhibitor, herceptin, and/or hki-272
US8022216B2 (en) 2007-10-17 2011-09-20 Wyeth Llc Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof
ES2835349T3 (en) 2008-06-17 2021-06-22 Wyeth Llc Antineoplastic combinations containing HKI-272 and vinorelbine
CN105963313A (en) 2008-08-04 2016-09-28 惠氏有限责任公司 Antineoplastic combinations of 4-anilino-3-cyanoquinolines and capecitabine
IL264349B2 (en) 2009-04-06 2024-01-01 Wyeth Llc Regimen comprising neratinib for the treatment of cancer
ES2757882T5 (en) * 2009-11-09 2023-05-10 Wyeth Llc Tablet formulations of neratinib maleate
NZ599762A (en) 2009-11-09 2014-07-25 Wyeth Llc Coated drug spheroids and uses thereof for eliminating or reducing conditions such as emesis and diarrhea
CN104447541A (en) * 2013-09-16 2015-03-25 天津市汉康医药生物技术有限公司 Bosutinib compound
CN105384686B (en) * 2014-09-04 2019-07-26 连云港润众制药有限公司 A kind of bosutinib method for crystallising
EP3439639A1 (en) * 2016-04-08 2019-02-13 Shionogi & Co., Ltd. Stabilized solid dosage form
CN110461720A (en) 2017-03-31 2019-11-15 日精Asb机械株式会社 Resin container

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6297258B1 (en) 1998-09-29 2001-10-02 American Cyanamid Company Substituted 3-cyanoquinolines
PL208114B1 (en) * 2002-02-26 2011-03-31 Astrazeneca Ab Pharmaceutical formulation of iressa comprising a water-soluble cellulose derivative
MXPA06001590A (en) 2003-08-19 2006-05-19 Wyeth Corp Process for the preparation of 4-amino-3-quinolinecarbonitriles.
AU2005283422C1 (en) * 2004-09-17 2017-02-02 Eisai R & D Management Co., Ltd. Medicinal composition
PT1902029E (en) * 2005-07-01 2014-03-05 Wyeth Llc Crystalline forms of 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarb-onitrile and methods of preparing the same
WO2008053295A2 (en) * 2006-10-30 2008-05-08 Wockhardt Research Centre Pharmaceutical compositions of benzoquinolizine-2-carboxylic acid
CN101224185A (en) * 2007-12-11 2008-07-23 山东蓝金生物工程有限公司 Bosutinib sustained release implant for treating solid tumors

Also Published As

Publication number Publication date
AU2010266342A1 (en) 2012-01-19
EP2448563A2 (en) 2012-05-09
IL217298A0 (en) 2012-02-29
SG177309A1 (en) 2012-02-28
CN102470109A (en) 2012-05-23
RU2011152105A (en) 2013-08-10
CA2766067A1 (en) 2011-01-06
JP2011012063A (en) 2011-01-20
AR077546A1 (en) 2011-09-07
WO2011002857A2 (en) 2011-01-06
BRPI1015941A2 (en) 2016-04-19
MX2012000048A (en) 2012-01-27
WO2011002857A3 (en) 2011-03-10
KR20120046216A (en) 2012-05-09
TW201113050A (en) 2011-04-16

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