JP2010540488A - 糖タンパク質及びグリコシル化細胞及びそれらの調製方法 - Google Patents

糖タンパク質及びグリコシル化細胞及びそれらの調製方法 Download PDF

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Publication number
JP2010540488A
JP2010540488A JP2010526274A JP2010526274A JP2010540488A JP 2010540488 A JP2010540488 A JP 2010540488A JP 2010526274 A JP2010526274 A JP 2010526274A JP 2010526274 A JP2010526274 A JP 2010526274A JP 2010540488 A JP2010540488 A JP 2010540488A
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Prior art keywords
carbohydrate
peptide
cells
moiety
group
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JP2010526274A
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Japanese (ja)
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JP2010540488A5 (enExample
Inventor
ジュラ・デカニー
カロリー・アゴシュトン
イシュトヴァーン・バイザ
マリー・ベイストルップ
ラース・クレーガー
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Glycom AS
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Glycom AS
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Publication of JP2010540488A publication Critical patent/JP2010540488A/ja
Publication of JP2010540488A5 publication Critical patent/JP2010540488A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/549—Sugars, nucleosides, nucleotides or nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2010526274A 2007-09-25 2008-09-24 糖タンパク質及びグリコシル化細胞及びそれらの調製方法 Withdrawn JP2010540488A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200701381 2007-09-25
PCT/EP2008/062728 WO2009040363A1 (en) 2007-09-25 2008-09-24 Glycoproteins and glycosylated cells and a method for the preparation of the same

Publications (2)

Publication Number Publication Date
JP2010540488A true JP2010540488A (ja) 2010-12-24
JP2010540488A5 JP2010540488A5 (enExample) 2011-11-10

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ID=40089962

Family Applications (1)

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JP2010526274A Withdrawn JP2010540488A (ja) 2007-09-25 2008-09-24 糖タンパク質及びグリコシル化細胞及びそれらの調製方法

Country Status (7)

Country Link
US (1) US8785594B2 (enExample)
EP (1) EP2190857A1 (enExample)
JP (1) JP2010540488A (enExample)
CN (1) CN101821281A (enExample)
AU (1) AU2008303584C1 (enExample)
CA (1) CA2700587A1 (enExample)
WO (1) WO2009040363A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015172008A (ja) * 2014-03-11 2015-10-01 国立大学法人 東京大学 含窒素複素環化合物の製造方法

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9816122B2 (en) 2012-09-25 2017-11-14 Glycom A/S Glycoconjugate synthesis
CN106460024B (zh) 2014-06-27 2021-10-01 格礼卡姆股份公司 寡糖的制备
WO2022013143A1 (en) 2020-07-13 2022-01-20 Glycom A/S Oligosaccharide production
WO2023209068A1 (en) 2022-04-28 2023-11-02 Carbocalyx Gmbh Personalized anticancer vaccine comprising glycoengineered tumour cells or tumour cell fragments
WO2025032055A1 (en) * 2023-08-08 2025-02-13 Carbocalyx Gmbh Cyclic carbamate compounds for ligation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU206890B (en) 1986-10-13 1993-01-28 Sandoz Ag Process for producing sugar-modified somatostatin peptide derivatives and pharmaceutical compositions containing them as active components
DE4003574A1 (de) 1990-02-07 1991-08-08 Bayer Ag Neue dipeptide, verfahren zu ihrer herstellung und ihre verwendung als renininhibitoren in arzneimitteln

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015172008A (ja) * 2014-03-11 2015-10-01 国立大学法人 東京大学 含窒素複素環化合物の製造方法

Also Published As

Publication number Publication date
US20100261873A1 (en) 2010-10-14
CA2700587A1 (en) 2009-04-02
AU2008303584B2 (en) 2013-06-27
AU2008303584A1 (en) 2009-04-02
CN101821281A (zh) 2010-09-01
EP2190857A1 (en) 2010-06-02
AU2008303584C1 (en) 2013-10-10
WO2009040363A1 (en) 2009-04-02
US8785594B2 (en) 2014-07-22

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