JP2010540163A - 事前算出フィードフォワード制御と画像フィードバック制御とを介して細胞に対する制御を自動化し殲滅することで標的へエネルギを供給するようにしたフォトン利用の非侵襲的外科手術システム - Google Patents
事前算出フィードフォワード制御と画像フィードバック制御とを介して細胞に対する制御を自動化し殲滅することで標的へエネルギを供給するようにしたフォトン利用の非侵襲的外科手術システム Download PDFInfo
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US97669907P | 2007-10-01 | 2007-10-01 | |
| US98254207P | 2007-10-25 | 2007-10-25 | |
| US2194108P | 2008-01-18 | 2008-01-18 | |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6088690B1 (ja) * | 2016-05-13 | 2017-03-01 | マイクロ波化学株式会社 | マイクロ波処理装置、プログラム |
| WO2017195840A1 (ja) * | 2016-05-13 | 2017-11-16 | マイクロ波化学株式会社 | マイクロ波処理装置、プログラム |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130046357A1 (en) * | 2008-03-27 | 2013-02-21 | Joseph Neev | Tissue or nerve treatment device and method |
| EP2196240A1 (en) * | 2008-12-12 | 2010-06-16 | Koninklijke Philips Electronics N.V. | Therapeutic apparatus |
| EP2196241A1 (en) * | 2008-12-12 | 2010-06-16 | Koninklijke Philips Electronics N.V. | Therapeutic apparatus |
| DE102010001743B4 (de) * | 2010-02-10 | 2012-07-12 | Siemens Aktiengesellschaft | Vorrichtung mit einer Kombination aus einer Magnetresonanzvorrichtung und einer Strahlentherapievorrichtung |
| DE102010001746B4 (de) * | 2010-02-10 | 2012-03-22 | Siemens Aktiengesellschaft | Vorrichtung mit einer Kombination aus einer Magnetresonanzvorrichtung und einer Strahlentherapievorrichtung |
| WO2011127946A1 (en) * | 2010-04-15 | 2011-10-20 | Elekta Ab (Publ) | Radiotherapy apparatus |
| WO2011127947A1 (en) * | 2010-04-15 | 2011-10-20 | Elekta Ab (Publ) | Radiotherapy and imaging apparatus |
| WO2011133431A2 (en) * | 2010-04-16 | 2011-10-27 | New York University | Apparatus, systems, computer-accessible medium and methods for facilitating radio frequency hyperthermia and thermal contrast in a magnetic resonance imaging system |
| DE102010021099A1 (de) * | 2010-05-20 | 2011-11-24 | Siemens Aktiengesellschaft | Kombiniertes Magnetresonanz- und Bestrahlungssystem |
| BR112013000907A2 (pt) * | 2010-07-16 | 2017-10-31 | Univ Denmark Tech Dtu | composição, partícula nanodimensionada para uso em registro de imagem de raios-x e método para tratamento de uma condição ou doença associada ao crescimento indesejável de células em um indivíduo com necessidade dele |
| BR112013018044A2 (pt) * | 2011-01-18 | 2019-09-03 | Koninl Philips Electronics Nv | aparelho terapêutico, produto de programa de computador e método de renderização de uma região alvo atingível |
| EP2636428A1 (en) | 2012-03-08 | 2013-09-11 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Method for determining parameters to generate ultrasound intensity and device for the same |
| US9063387B1 (en) * | 2012-09-13 | 2015-06-23 | The Boeing Company | Systems and methods for applying directed energy to an object |
| US9938026B1 (en) | 2014-10-28 | 2018-04-10 | Michelle Corning | Energy beam propulsion system |
| US10629318B1 (en) | 2014-10-28 | 2020-04-21 | Michelle Corning | Neutron beam diffraction material treatment system |
| US9711252B1 (en) | 2014-10-28 | 2017-07-18 | Michelle Corning | High energy beam diffraction material treatment system |
| EP3299131B1 (en) * | 2015-05-20 | 2021-06-23 | Nissan Motor Co., Ltd. | Failure diagnostic device and failure diagnostic method |
| SE540237C2 (en) | 2016-09-12 | 2018-05-08 | P H Kleven As | Radiotherapy system comprising plurality of individually controllable particle beam sources |
| CN108042931A (zh) * | 2018-01-15 | 2018-05-18 | 西安大医数码科技有限公司 | 一种放射治疗系统 |
| US10946216B2 (en) * | 2018-12-28 | 2021-03-16 | Varian Medical Systems International Ag | Incorporating multiple targets in trajectory optimization for radiotherapy treatment planning |
| CN111184949B (zh) * | 2019-07-09 | 2022-04-15 | 重庆医科大学 | 一种聚焦超声消融系统及其控制方法 |
| US11679273B2 (en) * | 2020-09-24 | 2023-06-20 | Siemens Healthineers International Ag | Method and apparatus to deliver therapeutic radiation to a patient using field geography-based dose optimization |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0747079A (ja) * | 1993-08-05 | 1995-02-21 | Toshiba Corp | 超音波治療装置 |
| JP2006511265A (ja) * | 2002-12-23 | 2006-04-06 | インサイテック−テクソニクス リミテッド | 超音波治療における組織異常の修正 |
Family Cites Families (82)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4144457A (en) * | 1976-04-05 | 1979-03-13 | Albert Richard D | Tomographic X-ray scanning system |
| US4998268A (en) * | 1989-02-09 | 1991-03-05 | James Winter | Apparatus and method for therapeutically irradiating a chosen area using a diagnostic computer tomography scanner |
| US5452720A (en) * | 1990-09-05 | 1995-09-26 | Photoelectron Corporation | Method for treating brain tumors |
| US5291890A (en) * | 1991-08-29 | 1994-03-08 | General Electric Company | Magnetic resonance surgery using heat waves produced with focussed ultrasound |
| JP3325300B2 (ja) * | 1992-02-28 | 2002-09-17 | 株式会社東芝 | 超音波治療装置 |
| US5247935A (en) * | 1992-03-19 | 1993-09-28 | General Electric Company | Magnetic resonance guided focussed ultrasound surgery |
| JP3860227B2 (ja) * | 1993-03-10 | 2006-12-20 | 株式会社東芝 | Mriガイド下で用いる超音波治療装置 |
| DE69431741T2 (de) * | 1993-03-12 | 2003-09-11 | Kabushiki Kaisha Toshiba, Kawasaki | Vorrichtung zur medizinischen Behandlung mit Ultraschall |
| US5307812A (en) * | 1993-03-26 | 1994-05-03 | General Electric Company | Heat surgery system monitored by real-time magnetic resonance profiling |
| SE502723C2 (sv) * | 1993-06-15 | 1995-12-18 | Elekta Instr Ab | Stereotaktiskt instrument |
| US5368031A (en) * | 1993-08-29 | 1994-11-29 | General Electric Company | Magnetic resonance surgery using heat waves produced with a laser fiber |
| US5368032A (en) * | 1993-11-09 | 1994-11-29 | General Electric Company | Manually positioned focussed energy system guided by medical imaging |
| US5526814A (en) * | 1993-11-09 | 1996-06-18 | General Electric Company | Automatically positioned focussed energy system guided by medical imaging |
| EP0673661B1 (en) * | 1994-03-25 | 2003-03-12 | Kabushiki Kaisha Toshiba | Radiotherapy system |
| US5492122A (en) * | 1994-04-15 | 1996-02-20 | Northrop Grumman Corporation | Magnetic resonance guided hyperthermia |
| US5537452A (en) * | 1994-05-10 | 1996-07-16 | Shepherd; Joseph S. | Radiation therapy and radiation surgery treatment system and methods of use of same |
| US5528651A (en) * | 1994-06-09 | 1996-06-18 | Elekta Instrument Ab | Positioning device and method for radiation treatment |
| US5443068A (en) * | 1994-09-26 | 1995-08-22 | General Electric Company | Mechanical positioner for magnetic resonance guided ultrasound therapy |
| DE19515748A1 (de) * | 1995-04-28 | 1996-10-31 | Siemens Ag | Gerät zur Behandlung mit akustischen Wellen |
| US5553112A (en) * | 1995-06-06 | 1996-09-03 | Medical Instrumentation And Diagnostics Corp. | Laser measuring apparatus and method for radiosurgery/stereotactic radiotherapy alignment |
| US5690109A (en) * | 1995-06-23 | 1997-11-25 | Govind; Rakesh | Method of destructive, noninvasive hyperpyrexia of tissues and organisms utilizing nuclear magnetic resonance |
| GB9520564D0 (en) * | 1995-10-07 | 1995-12-13 | Philips Electronics Nv | Apparatus for treating a patient |
| JP3902233B2 (ja) * | 1995-12-14 | 2007-04-04 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | 磁気共鳴イメージ化によって導かれた超音波による加熱処理の方法及び装置 |
| US5818902A (en) * | 1996-03-01 | 1998-10-06 | Elekta Ab | Intensity modulated arc therapy with dynamic multi-leaf collimation |
| US5778043A (en) * | 1996-09-20 | 1998-07-07 | Cosman; Eric R. | Radiation beam control system |
| US5899857A (en) * | 1997-01-07 | 1999-05-04 | Wilk; Peter J. | Medical treatment method with scanner input |
| EP0998217B1 (en) * | 1997-05-23 | 2009-01-07 | ProRhythm, Inc. | Disposable high intensity focused ultrasound applicator |
| WO1999003397A1 (en) | 1997-07-17 | 1999-01-28 | Medlennium Technologies, Inc. | Method and apparatus for radiation and hyperthermia therapy of tumors |
| US6398734B1 (en) * | 1997-10-14 | 2002-06-04 | Vascusense, Inc. | Ultrasonic sensors for monitoring the condition of flow through a cardiac valve |
| US5960054A (en) * | 1997-11-26 | 1999-09-28 | Picker International, Inc. | Angiographic system incorporating a computerized tomographic (CT) scanner |
| US6198957B1 (en) * | 1997-12-19 | 2001-03-06 | Varian, Inc. | Radiotherapy machine including magnetic resonance imaging system |
| GB9803351D0 (en) * | 1998-02-17 | 1998-04-15 | Oxford Biomedica Ltd | Anti-viral vectors |
| US6393096B1 (en) * | 1998-05-27 | 2002-05-21 | Nomos Corporation | Planning method and apparatus for radiation dosimetry |
| US6645464B1 (en) * | 1998-07-30 | 2003-11-11 | James F. Hainfeld | Loading metal particles into cell membrane vesicles and metal particular use for imaging and therapy |
| US20020001567A1 (en) * | 1998-12-21 | 2002-01-03 | Photogen, Inc. | Intracorporeal medicaments for high energy phototherapeutic treatment of disease |
| SE520276C2 (sv) * | 1999-01-25 | 2003-06-17 | Elekta Ab | Anordning för kontrollerat förstörande av vävnad |
| US6778850B1 (en) * | 1999-03-16 | 2004-08-17 | Accuray, Inc. | Frameless radiosurgery treatment system and method |
| US6389100B1 (en) * | 1999-04-09 | 2002-05-14 | Osmic, Inc. | X-ray lens system |
| GB2354876B (en) * | 1999-08-10 | 2004-06-02 | Elekta Ab | Linear accelerator |
| US6442748B1 (en) * | 1999-08-31 | 2002-08-27 | Accenture Llp | System, method and article of manufacture for a persistent state and persistent object separator in an information services patterns environment |
| US7520856B2 (en) * | 1999-09-17 | 2009-04-21 | University Of Washington | Image guided high intensity focused ultrasound device for therapy in obstetrics and gynecology |
| US6675037B1 (en) * | 1999-09-29 | 2004-01-06 | Regents Of The University Of Minnesota | MRI-guided interventional mammary procedures |
| US6725078B2 (en) * | 2000-01-31 | 2004-04-20 | St. Louis University | System combining proton beam irradiation and magnetic resonance imaging |
| US6768925B2 (en) * | 2000-04-13 | 2004-07-27 | Celsion Corporation | Method for improved safety in externally focused microwave thermotherapy for treating breast cancer |
| US6449336B2 (en) * | 2000-05-19 | 2002-09-10 | Siyong Kim | Multi-source intensity-modulated radiation beam delivery system and method |
| US6418337B1 (en) * | 2000-06-15 | 2002-07-09 | Autolitt Inc. | MRI guided hyperthermia surgery |
| US6477426B1 (en) * | 2000-06-20 | 2002-11-05 | Celsion Corporation | System and method for heating the prostate gland to treat and prevent the growth and spread of prostate tumors |
| JP2002177406A (ja) * | 2000-12-14 | 2002-06-25 | Mitsubishi Electric Corp | 放射線照射システム及びその照射ターゲット動きモニタ方法並びに照射ターゲット定位化方法 |
| US6694169B2 (en) * | 2001-02-22 | 2004-02-17 | Minrad Inc. | Targeting system and method of targeting |
| FR2823677B1 (fr) * | 2001-04-20 | 2004-01-09 | Centre Nat Rech Scient | Ensemble pour le traitement thermique de tissus biologiques |
| US6735461B2 (en) * | 2001-06-19 | 2004-05-11 | Insightec-Txsonics Ltd | Focused ultrasound system with MRI synchronization |
| US6914959B2 (en) * | 2001-08-09 | 2005-07-05 | Analogic Corporation | Combined radiation therapy and imaging system and method |
| EP1421833A4 (en) * | 2001-08-30 | 2006-04-05 | Tolemac Llc | ANTIPROTONE PRODUCTION AND RELEASE FOR THE PRESENTATION AND TERMINATION OF UNWANTED CELLS |
| US6856668B1 (en) * | 2002-01-25 | 2005-02-15 | Carl Zeiss Ag | Method of treating a tumor by pre-irradiation |
| US7218766B2 (en) * | 2002-04-15 | 2007-05-15 | General Electric Company | Computer aided detection (CAD) for 3D digital mammography |
| US6735277B2 (en) * | 2002-05-23 | 2004-05-11 | Koninklijke Philips Electronics N.V. | Inverse planning for intensity-modulated radiotherapy |
| US6768952B2 (en) * | 2002-10-21 | 2004-07-27 | Hewlett-Packard Development Company, L.P. | System and method of measuring low impedances |
| EP1614070B1 (en) * | 2003-01-21 | 2006-12-06 | ELEKTA AB (publ.) | Imaging internal structures |
| WO2005011804A2 (en) * | 2003-07-31 | 2005-02-10 | Costantino Peter D | Ultasound treatment and imaging system |
| US7204640B2 (en) * | 2003-08-29 | 2007-04-17 | Accuray, Inc. | Apparatus and method for registering 2D radiographic images with images reconstructed from 3D scan data |
| EP1673146B1 (en) * | 2003-09-30 | 2012-11-14 | Koninklijke Philips Electronics N.V. | Target tracking apparatus for radiation treatment planning and delivery |
| US20050080332A1 (en) * | 2003-10-10 | 2005-04-14 | Shiu Almon S. | Near simultaneous computed tomography image-guided stereotactic radiotherapy |
| US20050090732A1 (en) * | 2003-10-28 | 2005-04-28 | Triton Biosystems, Inc. | Therapy via targeted delivery of nanoscale particles |
| JP5110881B2 (ja) | 2004-02-20 | 2012-12-26 | ユニバーシティ オブ フロリダ リサーチ ファウンデーション,インコーポレイティド | 軟組織を同時に画像化しながら等角放射線治療を送達するためのシステム |
| US8160205B2 (en) * | 2004-04-06 | 2012-04-17 | Accuray Incorporated | Robotic arm for patient positioning assembly |
| US7708751B2 (en) * | 2004-05-21 | 2010-05-04 | Ethicon Endo-Surgery, Inc. | MRI biopsy device |
| US7200202B2 (en) * | 2004-06-03 | 2007-04-03 | Siemens Medical Solutions Usa, Inc. | Linear accelerator with x-ray imaging elements mounted on rotating support |
| US7130372B2 (en) * | 2004-06-08 | 2006-10-31 | Siemens Medical Solutions Usa, Inc. | Linear accelerator with X-ray imaging elements mounted on curved support |
| US7699780B2 (en) * | 2004-08-11 | 2010-04-20 | Insightec—Image-Guided Treatment Ltd. | Focused ultrasound system with adaptive anatomical aperture shaping |
| US20060153330A1 (en) * | 2004-08-19 | 2006-07-13 | Wong John W | System for radiation imaging and therapy of small animals |
| DE102004062473B4 (de) * | 2004-09-30 | 2006-11-30 | Siemens Ag | Medizinische Strahlentherapieanordnung |
| JP2008519642A (ja) * | 2004-11-12 | 2008-06-12 | ケーピーイー リミテッド | ナノ粒子を介した超音波治療および診断影像法 |
| US7194063B2 (en) * | 2005-02-10 | 2007-03-20 | Brookhaven Science Associates, Llc | Methods for implementing microbeam radiation therapy |
| US7492858B2 (en) * | 2005-05-20 | 2009-02-17 | Varian Medical Systems, Inc. | System and method for imaging and treatment of tumorous tissue in breasts using computed tomography and radiotherapy |
| US7302033B2 (en) * | 2005-06-29 | 2007-11-27 | Accuray Incorporated | Imaging geometry for image-guided radiosurgery |
| KR20080039920A (ko) * | 2005-07-22 | 2008-05-07 | 토모테라피 인코포레이티드 | 방사선 치료 시스템에 의해 부여되는 선량을 평가하는시스템 및 방법 |
| EP1968473A2 (en) * | 2005-12-14 | 2008-09-17 | Mobilestream Oil Inc. | Device producing and use of microwave energy for thermotherapy |
| US20070221869A1 (en) * | 2006-03-22 | 2007-09-27 | Shi Peng Song | Radiotherapy apparatus |
| US7620144B2 (en) * | 2006-06-28 | 2009-11-17 | Accuray Incorporated | Parallel stereovision geometry in image-guided radiosurgery |
| US8243877B2 (en) * | 2006-09-12 | 2012-08-14 | Weil Michael D | Dual-use radiation system |
| US8328785B2 (en) * | 2006-09-18 | 2012-12-11 | The University Of Houston System | Use of nanoparticles in the photodynamic treatment of tumors |
| US20080167548A1 (en) * | 2007-01-04 | 2008-07-10 | Sorensen Alma G | Tissue Alteration With MRI RF Field |
-
2008
- 2008-09-30 US US12/242,577 patent/US20090088625A1/en not_active Abandoned
- 2008-10-01 AU AU2008307601A patent/AU2008307601A1/en not_active Abandoned
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- 2008-10-01 MX MX2010003658A patent/MX2010003658A/es not_active Application Discontinuation
- 2008-10-01 WO PCT/US2008/011329 patent/WO2009045411A2/en not_active Ceased
- 2008-10-01 EP EP08836023A patent/EP2219731A2/en not_active Withdrawn
- 2008-10-01 CA CA2701628A patent/CA2701628A1/en not_active Abandoned
- 2008-10-01 JP JP2010527969A patent/JP2010540163A/ja active Pending
- 2008-10-01 BR BRPI0818453A patent/BRPI0818453A2/pt not_active IP Right Cessation
-
2010
- 2010-04-06 IL IL204882A patent/IL204882A0/en unknown
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0747079A (ja) * | 1993-08-05 | 1995-02-21 | Toshiba Corp | 超音波治療装置 |
| JP2006511265A (ja) * | 2002-12-23 | 2006-04-06 | インサイテック−テクソニクス リミテッド | 超音波治療における組織異常の修正 |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6088690B1 (ja) * | 2016-05-13 | 2017-03-01 | マイクロ波化学株式会社 | マイクロ波処理装置、プログラム |
| WO2017195840A1 (ja) * | 2016-05-13 | 2017-11-16 | マイクロ波化学株式会社 | マイクロ波処理装置、プログラム |
| US10850252B2 (en) | 2016-05-13 | 2020-12-01 | Microwave Chemical Co., Ltd. | Microwave treatment apparatus and program |
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| CA2701628A1 (en) | 2009-04-09 |
| IL204882A0 (en) | 2010-11-30 |
| EP2219731A2 (en) | 2010-08-25 |
| CN101883608A (zh) | 2010-11-10 |
| KR20100099103A (ko) | 2010-09-10 |
| WO2009045411A3 (en) | 2009-11-19 |
| AU2008307601A1 (en) | 2009-04-09 |
| MX2010003658A (es) | 2014-09-18 |
| BRPI0818453A2 (pt) | 2019-09-24 |
| US20090088625A1 (en) | 2009-04-02 |
| WO2009045411A2 (en) | 2009-04-09 |
| WO2009045411A9 (en) | 2009-10-01 |
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