JP2010535015A - 免疫原性のポリペプチドおよびモノクローナル抗体 - Google Patents

免疫原性のポリペプチドおよびモノクローナル抗体 Download PDF

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Publication number
JP2010535015A
JP2010535015A JP2010517242A JP2010517242A JP2010535015A JP 2010535015 A JP2010535015 A JP 2010535015A JP 2010517242 A JP2010517242 A JP 2010517242A JP 2010517242 A JP2010517242 A JP 2010517242A JP 2010535015 A JP2010535015 A JP 2010535015A
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seq
produced
hybridoma
nucleic acid
mouse
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JP2010517242A
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English (en)
Japanese (ja)
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JP2010535015A5 (OSRAM
Inventor
オクス,マルティナ
ブルックス,ロジャー
チャールボイス,ロバート
イェソン,ジェレミー
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Sanofi Pasteur Ltd
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Sanofi Pasteur Ltd
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Publication of JP2010535015A publication Critical patent/JP2010535015A/ja
Publication of JP2010535015A5 publication Critical patent/JP2010535015A5/ja
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1275Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Streptococcus (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/56944Streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507Comprising a combination of two or more separate antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pathology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Neurosurgery (AREA)
  • Oncology (AREA)
JP2010517242A 2007-07-23 2008-07-23 免疫原性のポリペプチドおよびモノクローナル抗体 Pending JP2010535015A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96172307P 2007-07-23 2007-07-23
PCT/CA2008/001353 WO2009012588A1 (en) 2007-07-23 2008-07-23 Immunogenic polypeptides and monoclonal antibodies

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013089148A Division JP6204053B2 (ja) 2007-07-23 2013-04-22 免疫原性のポリペプチドおよびモノクローナル抗体

Publications (2)

Publication Number Publication Date
JP2010535015A true JP2010535015A (ja) 2010-11-18
JP2010535015A5 JP2010535015A5 (OSRAM) 2011-08-11

Family

ID=40280955

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2010517242A Pending JP2010535015A (ja) 2007-07-23 2008-07-23 免疫原性のポリペプチドおよびモノクローナル抗体
JP2013089148A Expired - Fee Related JP6204053B2 (ja) 2007-07-23 2013-04-22 免疫原性のポリペプチドおよびモノクローナル抗体
JP2015196681A Pending JP2016005482A (ja) 2007-07-23 2015-10-02 免疫原性のポリペプチドおよびモノクローナル抗体

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2013089148A Expired - Fee Related JP6204053B2 (ja) 2007-07-23 2013-04-22 免疫原性のポリペプチドおよびモノクローナル抗体
JP2015196681A Pending JP2016005482A (ja) 2007-07-23 2015-10-02 免疫原性のポリペプチドおよびモノクローナル抗体

Country Status (12)

Country Link
US (1) US8337846B2 (OSRAM)
EP (1) EP2183366B1 (OSRAM)
JP (3) JP2010535015A (OSRAM)
KR (1) KR101595234B1 (OSRAM)
CN (1) CN101802198B (OSRAM)
AU (1) AU2008280799B2 (OSRAM)
BR (1) BRPI0814127A2 (OSRAM)
CA (1) CA2694466A1 (OSRAM)
ES (1) ES2397488T3 (OSRAM)
IL (1) IL203429A0 (OSRAM)
WO (1) WO2009012588A1 (OSRAM)
ZA (1) ZA201001260B (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021518559A (ja) * 2018-03-20 2021-08-02 サノフィ パスツ−ル リミテッドSanofi Pasteur Limited 固有蛍光を使用して、アジュバント化タンパク質濃度及びパーセント吸着を決定する方法

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US7128918B1 (en) 1998-12-23 2006-10-31 Id Biomedical Corporation Streptococcus antigens
JP5894083B2 (ja) 2009-12-22 2016-03-23 サノフィ パストゥール リミテッドSanofi Pasteur Limited 免疫原性組成物
WO2011075822A1 (en) 2009-12-22 2011-06-30 Sanofi Pasteur Limited Immunogenic compositions and related methods
GB201003920D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Method of treatment
KR20140009281A (ko) 2010-12-03 2014-01-22 사노피 파스퇴르 리미티드 / 사노피 파스퇴르 리미떼 스트렙토코커스 뉴모니애에 대한 면역화를 위한 조성물
WO2012156391A1 (en) 2011-05-17 2012-11-22 Glaxosmithkline Biologicals S.A. Vaccine against streptococcus pneumoniae
JP2015508755A (ja) 2012-02-01 2015-03-23 オクラホマ メディカル リサーチ ファウンデーションOklahoma Medical Researchfoundation ヒト肺炎連鎖球菌抗体およびその使用
GB201518684D0 (en) 2015-10-21 2015-12-02 Glaxosmithkline Biolog Sa Vaccine
CN105754952B (zh) * 2016-02-16 2020-07-10 中国农业科学院兰州兽医研究所 抗羊痘病毒k3l蛋白c末端的单克隆抗体及其应用
GB201610599D0 (en) 2016-06-17 2016-08-03 Glaxosmithkline Biologicals Sa Immunogenic Composition
WO2022173689A1 (en) * 2021-02-09 2022-08-18 University Of Georgia Research Foundation, Inc. Human monoclonal antibodies against pneumococcal antigens

Citations (1)

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WO2003054007A2 (en) * 2001-12-20 2003-07-03 Shire Biochem Inc. Streptococcus antigens

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IL81370A (en) * 1986-02-07 1991-06-30 Genetic Systems Corp Pharmaceutical and diagnostic compositions comprising a plurality of human monoclonal antibodies for the treatment of bacterial diseases,methods for the preparation of the compositions and antibodies and kits containing said compositions
AU681573B2 (en) * 1991-11-22 1997-09-04 Glaxosmithkline Biologicals Sa Type I and type II surface antigens associated with (staphylococcus epidermidis)
US6582708B1 (en) * 2000-06-28 2003-06-24 The Procter & Gamble Company Tooth whitening substance
US6582706B1 (en) 1998-12-21 2003-06-24 Medimmune, Inc. Vaccine compositions comprising Streptococcus pneumoniae polypeptides having selected structural MOTIFS
US7128918B1 (en) * 1998-12-23 2006-10-31 Id Biomedical Corporation Streptococcus antigens
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WO2000058475A2 (en) * 1999-03-26 2000-10-05 Provalis Uk Limited Streptococcus pneumoniae antigens
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EP2281891A3 (en) * 2000-06-20 2011-08-17 ID Biomedical Corporation Streptococcus antigens
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021518559A (ja) * 2018-03-20 2021-08-02 サノフィ パスツ−ル リミテッドSanofi Pasteur Limited 固有蛍光を使用して、アジュバント化タンパク質濃度及びパーセント吸着を決定する方法
JP7413271B2 (ja) 2018-03-20 2024-01-15 サノフィ パスツ-ル リミテッド 固有蛍光を使用して、アジュバント化タンパク質濃度及びパーセント吸着を決定する方法

Also Published As

Publication number Publication date
CN101802198B (zh) 2016-02-17
ES2397488T3 (es) 2013-03-07
US8337846B2 (en) 2012-12-25
ZA201001260B (en) 2010-10-27
CN101802198A (zh) 2010-08-11
AU2008280799A1 (en) 2009-01-29
JP2016005482A (ja) 2016-01-14
JP6204053B2 (ja) 2017-09-27
IL203429A0 (en) 2011-07-31
BRPI0814127A2 (pt) 2015-02-03
KR20100053564A (ko) 2010-05-20
CA2694466A1 (en) 2009-01-29
JP2013212108A (ja) 2013-10-17
US20100297133A1 (en) 2010-11-25
EP2183366B1 (en) 2012-10-24
KR101595234B1 (ko) 2016-02-26
AU2008280799B2 (en) 2013-07-11
EP2183366A4 (en) 2010-09-01
WO2009012588A1 (en) 2009-01-29
EP2183366A1 (en) 2010-05-12

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