JP2010534464A5 - - Google Patents

Download PDF

Info

Publication number
JP2010534464A5
JP2010534464A5 JP2010517326A JP2010517326A JP2010534464A5 JP 2010534464 A5 JP2010534464 A5 JP 2010534464A5 JP 2010517326 A JP2010517326 A JP 2010517326A JP 2010517326 A JP2010517326 A JP 2010517326A JP 2010534464 A5 JP2010534464 A5 JP 2010534464A5
Authority
JP
Japan
Prior art keywords
peptide
cell
variant
antigen
tumor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2010517326A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010534464A (ja
JP6008461B2 (ja
Filing date
Publication date
Priority claimed from EP08005889.4A external-priority patent/EP2105501B1/en
Application filed filed Critical
Priority claimed from PCT/EP2008/006154 external-priority patent/WO2009015843A1/en
Publication of JP2010534464A publication Critical patent/JP2010534464A/ja
Publication of JP2010534464A5 publication Critical patent/JP2010534464A5/ja
Application granted granted Critical
Publication of JP6008461B2 publication Critical patent/JP6008461B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2010517326A 2007-07-27 2008-07-25 神経細胞性脳腫瘍に対する新規免疫療法 Expired - Fee Related JP6008461B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
EP07014797 2007-07-27
EP07014797.0 2007-07-27
US95316107P 2007-07-31 2007-07-31
US60/953,161 2007-07-31
EP08005889.4A EP2105501B1 (en) 2008-03-27 2008-03-27 Novel immunotherapy against neuronal and brain tumors
EP08005889.4 2008-03-27
PCT/EP2008/006154 WO2009015843A1 (en) 2007-07-27 2008-07-25 Novel immunotherapy against neuronal and brain tumors

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013112532A Division JP5738348B2 (ja) 2007-07-27 2013-05-29 神経細胞性脳腫瘍に対する新規免疫療法

Publications (3)

Publication Number Publication Date
JP2010534464A JP2010534464A (ja) 2010-11-11
JP2010534464A5 true JP2010534464A5 (enExample) 2010-12-24
JP6008461B2 JP6008461B2 (ja) 2016-10-19

Family

ID=39720257

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2010517326A Expired - Fee Related JP6008461B2 (ja) 2007-07-27 2008-07-25 神経細胞性脳腫瘍に対する新規免疫療法
JP2013112532A Expired - Fee Related JP5738348B2 (ja) 2007-07-27 2013-05-29 神経細胞性脳腫瘍に対する新規免疫療法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2013112532A Expired - Fee Related JP5738348B2 (ja) 2007-07-27 2013-05-29 神経細胞性脳腫瘍に対する新規免疫療法

Country Status (21)

Country Link
US (6) US9175040B2 (enExample)
EP (2) EP2660248B1 (enExample)
JP (2) JP6008461B2 (enExample)
KR (2) KR101290892B1 (enExample)
CN (2) CN101809148B (enExample)
AU (1) AU2008281015B2 (enExample)
BR (1) BRPI0813621A2 (enExample)
CA (2) CA2694808C (enExample)
CY (1) CY1117115T1 (enExample)
DK (2) DK2183361T3 (enExample)
EA (2) EA034800B1 (enExample)
ES (2) ES2546610T3 (enExample)
HR (2) HRP20150820T1 (enExample)
HU (1) HUE027524T2 (enExample)
MX (1) MX2010001086A (enExample)
NZ (2) NZ592261A (enExample)
PL (2) PL2660248T3 (enExample)
PT (2) PT2660248E (enExample)
RS (2) RS54147B1 (enExample)
SI (2) SI2183361T1 (enExample)
WO (1) WO2009015843A1 (enExample)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090004213A1 (en) 2007-03-26 2009-01-01 Immatics Biotechnologies Gmbh Combination therapy using active immunotherapy
RS54147B1 (sr) 2007-07-27 2015-12-31 Immatics Biotechnologies Gmbh Nova imunoterapija protiv tumora mozga
US8530429B2 (en) 2009-11-24 2013-09-10 Arch Cancer Therapeutics, Inc. Brain tumor targeting peptides and methods
US9095541B2 (en) 2009-11-24 2015-08-04 Arch Cancer Therapeutics, Inc. Brain tumor targeting peptides and methods
EP2661622B1 (en) * 2011-01-05 2017-11-08 Wisconsin Alumni Research Foundation Bystander immune suppression as a predictor for response to a vaccine
GB201319446D0 (en) 2013-11-04 2013-12-18 Immatics Biotechnologies Gmbh Personalized immunotherapy against several neuronal and brain tumors
CN104698059B (zh) * 2013-12-04 2017-07-21 苏州中赢医疗科技有限公司 一种脑胶质瘤肿瘤标志物及其应用
GB201501017D0 (en) * 2014-12-23 2015-03-04 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers
US20180133327A1 (en) 2015-03-16 2018-05-17 Amal Therapeutics Sa Cell Penetrating Peptides and Complexes Comprising the Same
MY199500A (en) 2015-03-17 2023-11-01 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against pancreatic cancer and other cancers
NL2014935B1 (en) 2015-06-08 2017-02-03 Applied Immune Tech Ltd T cell receptor like antibodies having fine specificity.
GB201511546D0 (en) 2015-07-01 2015-08-12 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers
CN108026154B (zh) 2015-07-01 2022-03-08 伊玛提克斯生物技术有限公司 用于卵巢癌和其他癌症免疫治疗的新型肽和肽组合物
IL256303B2 (en) 2015-07-06 2025-02-01 Immatics Biotechnologies Gmbh New peptides and peptide combinations for use in immunotherapy against esophageal cancer and other cancers
MY189596A (en) * 2015-07-15 2022-02-18 Immatics Biotechnologies Gmbh A novel peptides for use in immunotherapy against epithelial ovarian cancer and other cancers
TWI803835B (zh) * 2015-08-28 2023-06-01 德商英麥提克生物技術股份有限公司 用於多種癌症之免疫治療的新穎胜肽、胜肽的組合物及支架
GB201515321D0 (en) * 2015-08-28 2015-10-14 Immatics Biotechnologies Gmbh Novel peptides, combination of peptides and scaffolds for use in immunotherapeutic treatment of various cancers
KR102883915B1 (ko) 2015-12-16 2025-11-18 시애틀 프로젝트 코포레이션 신생항원 동정, 제조, 및 용도
CA3010779A1 (en) 2016-03-16 2017-09-21 Amal Therapeutics Sa Combination of an immune checkpoint modulator and a complex comprising a cell penetrating peptide, a cargo and a tlr peptide agonist for use in medicine
WO2018026914A1 (en) * 2016-08-02 2018-02-08 Nantcell, Inc. Transfection of dendritic cells and methods therefor
EP3515476B1 (en) 2016-09-21 2024-05-22 Amal Therapeutics SA Fusion comprising a cell penetrating peptide, a multiepitope and a tlr peptide agonist for treatment of cancer
NZ754222A (en) 2016-12-08 2022-02-25 Immatics Biotechnologies Gmbh T cell receptors with improved pairing
DE102016123893A1 (de) 2016-12-08 2018-06-14 Immatics Biotechnologies Gmbh T-Zellrezeptoren mit verbesserter Bindung
KR20190110612A (ko) 2017-02-01 2019-09-30 모더나티엑스, 인크. 활성화 종양유전자 돌연변이 펩티드를 인코드하는 면역조절 치료 mrna 조성물
SG10202107869QA (en) * 2017-04-10 2021-08-30 Immatics Biotechnologies Gmbh Peptides and combination thereof for use in the immunotherapy against cancers
JP7227237B2 (ja) 2017-10-10 2023-02-21 グリットストーン バイオ インコーポレイテッド ホットスポットを利用した新生抗原の特定
US11885815B2 (en) 2017-11-22 2024-01-30 Gritstone Bio, Inc. Reducing junction epitope presentation for neoantigens
JP2022535421A (ja) 2019-06-06 2022-08-08 イマティクス バイオテクノロジーズ ゲーエムベーハー 配列類似ペプチドを使用した対抗選択による選別
AU2020431140A1 (en) * 2020-02-24 2022-08-18 The Regents Of The University Of California Use of brain-specific antigens to home, block and deliver cell-based treatments to the brain
EP4405464A4 (en) * 2021-09-21 2025-12-03 Univ Chicago METHODS AND COMPOSITION USING PATIENT-DERIVED AUTOLOGOUS NEOANTIGENS FOR CANCER TREATMENT

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4440859A (en) 1977-05-27 1984-04-03 The Regents Of The University Of California Method for producing recombinant bacterial plasmids containing the coding sequences of higher organisms
US4704362A (en) 1977-11-08 1987-11-03 Genentech, Inc. Recombinant cloning vehicle microbial polypeptide expression
DD147855A5 (de) 1978-12-22 1981-04-22 Biogen Nv Verfahren zur erzeugung mindestens eines hbv-antigenwirkung aufweisenden polypeptids
US4530901A (en) 1980-01-08 1985-07-23 Biogen N.V. Recombinant DNA molecules and their use in producing human interferon-like polypeptides
US4678751A (en) 1981-09-25 1987-07-07 Genentech, Inc. Hybrid human leukocyte interferons
US4766075A (en) 1982-07-14 1988-08-23 Genentech, Inc. Human tissue plasminogen activator
US4582800A (en) 1982-07-12 1986-04-15 Hoffmann-La Roche Inc. Novel vectors and method for controlling interferon expression
JPS6081130A (ja) * 1983-10-07 1985-05-09 Fujisawa Pharmaceut Co Ltd 抗hla−a2抗体およびそれを産生するハイブリド−マ
US4757006A (en) 1983-10-28 1988-07-12 Genetics Institute, Inc. Human factor VIII:C gene and recombinant methods for production
US4677063A (en) 1985-05-02 1987-06-30 Cetus Corporation Human tumor necrosis factor
US4810648A (en) 1986-01-08 1989-03-07 Rhone Poulenc Agrochimie Haloarylnitrile degrading gene, its use, and cells containing the gene
US4897445A (en) 1986-06-27 1990-01-30 The Administrators Of The Tulane Educational Fund Method for synthesizing a peptide containing a non-peptide bond
US5651972A (en) * 1989-04-21 1997-07-29 University Of Florida Research Foundation, Inc. Use of recombinant swine poxvirus as a live vaccine vector
US5202666A (en) * 1991-01-18 1993-04-13 Net/Tech International Inc. Method and apparatus for enhancing hygiene
AUPM322393A0 (en) 1993-12-24 1994-01-27 Austin Research Institute, The Mucin carbohydrate compounds and their use in immunotherapy
EP0819171A1 (en) * 1995-04-07 1998-01-21 The Regents Of The University Of California Antibodies for the detection of hla-g
EP0879282B1 (en) 1996-01-17 2003-07-02 Imperial College Innovations Limited Immunotherapy using cytotoxic t lymphocytes (ctl)
US5849589A (en) 1996-03-11 1998-12-15 Duke University Culturing monocytes with IL-4, TNF-α and GM-CSF TO induce differentiation to dendric cells
US6406705B1 (en) 1997-03-10 2002-06-18 University Of Iowa Research Foundation Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
DE19739089A1 (de) * 1997-09-06 1999-03-11 Hella Kg Hueck & Co Scheinwerfer für Fahrzeuge
CA2304208A1 (en) * 1997-09-19 1999-03-25 Dana-Farber Cancer Institute, Inc. Intrabody-mediated control of immune reactions
US6747137B1 (en) * 1998-02-13 2004-06-08 Genome Therapeutics Corporation Nucleic acid sequences relating to Candida albicans for diagnostics and therapeutics
EP1187924A1 (en) * 1999-06-03 2002-03-20 Cold Spring Harbor Laboratory Substrate trapping protein tyrosine phosphatases
US6455026B1 (en) 2001-03-23 2002-09-24 Agy Therapeutics, Inc. Use of protein tyrosine phosphatase zeta as a biomolecular target in the treatment and visualization of brain tumors
US20030118585A1 (en) * 2001-10-17 2003-06-26 Agy Therapeutics Use of protein biomolecular targets in the treatment and visualization of brain tumors
JP2003012544A (ja) * 2001-03-27 2003-01-15 Kouji Egawa 癌予防・治療剤
US20050260132A1 (en) * 2001-10-17 2005-11-24 Daniel Chin Monoclonal antibodies directed to receptor protein tyrosine phosphatase zeta
AU2002365187A1 (en) * 2001-11-07 2003-07-24 Mannkind Corporation Epitope synchronization in antigen presenting cells
WO2003042661A2 (en) * 2001-11-13 2003-05-22 Protein Design Labs, Inc. Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer
US7236577B2 (en) * 2002-11-14 2007-06-26 International Business Machines Corporation Call screening system and method
KR100494979B1 (ko) * 2003-07-14 2005-06-14 주식회사 정우인터내셔날 조직 절편 보호 및 해상력 증진용 액상 커버 슬립, 그제조용 조성물, 그로부터 제조된 커버슬립을 구비한슬라이드 구조체 및 그 제조방법
US7050785B2 (en) * 2003-12-08 2006-05-23 Research In Motion Limited Apparatus and method of explicit indication of call from emergency call centre
EP1716227A4 (en) * 2004-01-27 2010-01-06 Compugen Ltd METHOD OF IDENTIFYING PUTATIVE GENE PRODUCTS USING THE INTERSPEZIES SEQUENCE COMPARISON AND BIOMOLECULAR SEQUENCES DISCOVERED THEREFOR
DE102004026135A1 (de) 2004-05-25 2006-01-05 Immatics Biotechnologies Gmbh An MHC-Moleküle bindende Tumor-assoziierte Peptide
US7315736B2 (en) * 2004-09-30 2008-01-01 Jenkins Nevin C Personal emergency communication system
US7231200B2 (en) * 2004-09-30 2007-06-12 Nevin Jenkins Personal emergency communication system
ES2330013T3 (es) 2005-09-05 2009-12-03 Immatics Biotechnologies Gmbh Peptidos asociados a tumores unidos a moleculas del antigeno de leucocito humano (hla) de clase i o ii y vacunas contra el cancer relacionadas.
SI1806358T1 (sl) 2005-09-05 2010-06-30 Immatics Biotechnologies Gmbh S tumorjem povezani peptidi ki se promiskuitetnovežejo na molekule humanega levkocitnega antigena HLA razreda II
RS54147B1 (sr) * 2007-07-27 2015-12-31 Immatics Biotechnologies Gmbh Nova imunoterapija protiv tumora mozga
SI2113253T1 (sl) 2008-04-30 2010-06-30 Immatics Biotechnologies Gmbh Nove formulacije s tumorjem povezanih peptidov ki se vežejo na molekule humanega levkocitnega antigena HLA razreda I ali II za cepiva
PL2172211T3 (pl) * 2008-10-01 2015-05-29 Immatics Biotechnologies Gmbh Kompozycja związanych z guzem peptydów i związana z tym szczepionka przeciwrakowa do leczenia glejaka (GBM) i innych rodzajów raka
WO2015187040A1 (en) * 2014-06-05 2015-12-10 Regan James Anderson Amino sphingoglycolipid analogues

Similar Documents

Publication Publication Date Title
JP2010534464A5 (enExample)
AU2017331949B2 (en) Fusion comprising a cell penetrating peptide, a multi epitope and a TLR peptide agonist for treatment of cancer
van der Burg et al. Improved peptide vaccine strategies, creating synthetic artificial infections to maximize immune efficacy
JP2017502076A5 (enExample)
JP5166025B2 (ja) エピトープアナログ
JP2010534463A5 (enExample)
JP3819930B2 (ja) Wt1改変ペプチド
AU2016232659B2 (en) A novel complex comprising a cell penetrating peptide, a cargo and a TLR peptide agonist for treatment of colorectal cancer
CA2886631C (en) Pam3cys-like lipopeptide adjuvant compound in a vaccine composition
HRP20150852T1 (hr) Nova imunoterapija protiv tumora mozga
EA201892021A1 (ru) Трансфицированные t-клетки и t-клеточные рецепторы для применения в иммунотерапии раковых заболеваний
EA201891759A1 (ru) Трансфицированные t-клетки и t-клеточные рецепторы для применения в иммунотерапии раковых заболеваний
AU2018229741B2 (en) Peptides and methods for the treatment of diabetes
KR19990067653A (ko) 종양 백신 및 그의 제조 방법
AU2015233542B2 (en) A medicament for use in a method of inducing or extending a cellular cytotoxic immune response
JP6602377B2 (ja) 樹状細胞の製造方法、これにより製造された樹状細胞及びその用途
CA3111663A1 (en) Herv-k-derived antigens as shared tumor antigens for anti-cancer vaccine
JP5267969B2 (ja) 癌ワクチン
CN105330733A (zh) MHC II类分子提呈的存活蛋白(Survivin)的部分肽及其利用方法
Levy et al. A melanoma multiepitope polypeptide induces specific CD8+ T-cell response
CN101041816B (zh) 人工抗原递呈细胞及其制备方法
JP2021045150A5 (enExample)
Ahmadzadeh OR. 93. Tumor Antigen-specific CD8 T Cells Infiltrating the Tumor Express High Levels of PD-1 and are Functionally Impaired
Sabbagh et al. OR. 92. Human Glioblastoma Cancer Stem Cells Promote Intra-tumoral Immune Regulatory Functions
Feng et al. Inducement of antitumor-immunity by DC activated by Hsp70-H22 tumor antigen peptide