JP2010533645A5 - - Google Patents

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Publication number
JP2010533645A5
JP2010533645A5 JP2010510368A JP2010510368A JP2010533645A5 JP 2010533645 A5 JP2010533645 A5 JP 2010533645A5 JP 2010510368 A JP2010510368 A JP 2010510368A JP 2010510368 A JP2010510368 A JP 2010510368A JP 2010533645 A5 JP2010533645 A5 JP 2010533645A5
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JP
Japan
Prior art keywords
cdcl
nmr
mhz
alkyl
compound according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2010510368A
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English (en)
Japanese (ja)
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JP2010533645A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2008/006913 external-priority patent/WO2008150492A1/en
Publication of JP2010533645A publication Critical patent/JP2010533645A/ja
Publication of JP2010533645A5 publication Critical patent/JP2010533645A5/ja
Pending legal-status Critical Current

Links

JP2010510368A 2007-05-31 2008-05-30 脂肪酸アミドヒドロラーゼの三環系阻害剤 Pending JP2010533645A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93249407P 2007-05-31 2007-05-31
PCT/US2008/006913 WO2008150492A1 (en) 2007-05-31 2008-05-30 Tricyclic inhibitors of fatty acid amide hydrolase

Publications (2)

Publication Number Publication Date
JP2010533645A JP2010533645A (ja) 2010-10-28
JP2010533645A5 true JP2010533645A5 (https=) 2012-07-05

Family

ID=40094018

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010510368A Pending JP2010533645A (ja) 2007-05-31 2008-05-30 脂肪酸アミドヒドロラーゼの三環系阻害剤

Country Status (6)

Country Link
US (1) US8124778B2 (https=)
EP (1) EP2161997A4 (https=)
JP (1) JP2010533645A (https=)
AU (1) AU2008260496A1 (https=)
CA (1) CA2689148A1 (https=)
WO (1) WO2008150492A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2161997A4 (en) 2007-05-31 2011-04-06 Scripps Research Inst TRICYCLIC INHIBITORS OF FATTY ACID AMIDHYDROLASE
AU2015268638B2 (en) * 2009-10-02 2017-08-31 Avexxin As Anti inflammatory 2-oxothiazoles and 2-oxooxazoles
CA2782797C (en) * 2009-10-02 2018-08-07 Avexxin As Anti inflammatory 2-oxothiazoles and 2 -oxooxazoles
WO2011085216A2 (en) 2010-01-08 2011-07-14 Ironwood Pharmaceuticals, Inc. Use of faah inhibitors for treating parkinson's disease and restless legs syndrome
WO2011123719A2 (en) 2010-03-31 2011-10-06 Ironwood Pharmaceuticals, Inc. Use of faah inhibitors for treating abdominal, visceral and pelvic pain
CN103153307A (zh) * 2010-04-22 2013-06-12 默沙东公司 用作faah调节剂的噁唑衍生物
CN105102438B (zh) 2013-01-29 2019-04-30 埃维克辛公司 抗炎症和抗肿瘤的2-氧代噻唑类和2-氧代噻吩类化合物
GB201413695D0 (en) 2014-08-01 2014-09-17 Avexxin As Compound
CN104592144B (zh) * 2015-01-12 2017-02-22 上海鼎雅药物化学科技有限公司 制备噁唑衍生物的新方法
GB201604318D0 (en) 2016-03-14 2016-04-27 Avexxin As Combination therapy
WO2019173394A1 (en) * 2018-03-05 2019-09-12 Wylder Nation Foundation Compositions and methods for activating signaling through the cb1 cannabinoid receptor for treating and preventing diseases and disorders characterized by abnormal cellular accumulation of sphingolipids such as sphingomyelin
CN110804048A (zh) * 2019-11-08 2020-02-18 暨南大学 恶唑酮类化合物及其应用、faah的正电子药物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6462054B1 (en) * 2000-03-27 2002-10-08 The Scripps Research Institute Inhibitors of fatty acid amide hydrolase
EP1558591B1 (en) * 2002-10-07 2014-05-07 The Regents of The University of California Modulation of anxiety through blockade of anandamide hydrolysis
BR0314980A (pt) * 2002-10-08 2005-08-09 Scripps Research Inst Inibidores de hidrolase de amida de ácido graxo
US7351724B2 (en) * 2004-10-15 2008-04-01 The Scripps Research Institute Oxadiazole ketone inhibitors of fatty acid amide hydrolase
US20060167075A1 (en) * 2005-01-25 2006-07-27 Pearson James P Modulators of FAAH
JP2009527483A (ja) * 2006-02-17 2009-07-30 ザ・スクリプス・リサーチ・インステイチユート 脂肪酸アミドヒドロラーゼの調節因子としてのオキサゾールケトン
AU2008257154B2 (en) * 2007-05-25 2014-03-06 The Scripps Research Institute Tetracyclic inhibitors of fatty acid amide hydrolase
EP2161997A4 (en) 2007-05-31 2011-04-06 Scripps Research Inst TRICYCLIC INHIBITORS OF FATTY ACID AMIDHYDROLASE

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