JP2010532986A5 - - Google Patents
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- Publication number
- JP2010532986A5 JP2010532986A5 JP2010515596A JP2010515596A JP2010532986A5 JP 2010532986 A5 JP2010532986 A5 JP 2010532986A5 JP 2010515596 A JP2010515596 A JP 2010515596A JP 2010515596 A JP2010515596 A JP 2010515596A JP 2010532986 A5 JP2010532986 A5 JP 2010532986A5
- Authority
- JP
- Japan
- Prior art keywords
- nad
- sample
- nucleic acid
- dependent ligase
- acid molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000003960 Ligases Human genes 0.000 claims 48
- 108090000364 Ligases Proteins 0.000 claims 48
- 230000001419 dependent effect Effects 0.000 claims 44
- 150000007523 nucleic acids Chemical class 0.000 claims 33
- 102000039446 nucleic acids Human genes 0.000 claims 33
- 108020004707 nucleic acids Proteins 0.000 claims 33
- 241000894006 Bacteria Species 0.000 claims 24
- 230000000694 effects Effects 0.000 claims 24
- 238000000034 method Methods 0.000 claims 24
- 239000000758 substrate Substances 0.000 claims 20
- 244000005700 microbiome Species 0.000 claims 13
- 230000001580 bacterial effect Effects 0.000 claims 11
- 239000003795 chemical substances by application Substances 0.000 claims 7
- 239000003242 anti bacterial agent Substances 0.000 claims 6
- 210000004027 cell Anatomy 0.000 claims 6
- 108090000988 Lysostaphin Proteins 0.000 claims 4
- 101710163270 Nuclease Proteins 0.000 claims 4
- 238000002360 preparation method Methods 0.000 claims 4
- 210000002421 cell wall Anatomy 0.000 claims 3
- 239000000356 contaminant Substances 0.000 claims 3
- 230000009089 cytolysis Effects 0.000 claims 3
- 238000011534 incubation Methods 0.000 claims 3
- 230000003834 intracellular effect Effects 0.000 claims 3
- 239000000463 material Substances 0.000 claims 3
- 230000035699 permeability Effects 0.000 claims 3
- 239000013543 active substance Substances 0.000 claims 2
- 239000003153 chemical reaction reagent Substances 0.000 claims 2
- 238000011109 contamination Methods 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 208000015181 infectious disease Diseases 0.000 claims 2
- 238000012216 screening Methods 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- 230000006037 cell lysis Effects 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 238000010438 heat treatment Methods 0.000 claims 1
- 230000003100 immobilizing effect Effects 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 230000002147 killing effect Effects 0.000 claims 1
- 108010072532 lysostaphin endopeptidase Proteins 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 230000002829 reductive effect Effects 0.000 claims 1
- 238000011895 specific detection Methods 0.000 claims 1
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0713255A GB0713255D0 (en) | 2007-07-09 | 2007-07-09 | Improved methods and kits for detecting an enzyme capable of modifying a nucleic acid |
| GB0713972A GB0713972D0 (en) | 2007-07-09 | 2007-07-18 | Improved methods and kits for detecting an enzyme capable of modifying a nucleic acid |
| GB0719785A GB0719785D0 (en) | 2007-07-09 | 2007-10-10 | Improved detection of micro-organisms |
| GB0802857A GB0802857D0 (en) | 2008-02-15 | 2008-02-15 | Improved bacterial detection methods and kits |
| GB0807054A GB0807054D0 (en) | 2008-04-17 | 2008-04-17 | Improved detection of micro-organisms |
| PCT/GB2008/002354 WO2009007719A2 (en) | 2007-07-09 | 2008-07-09 | Detection of micro-organisms based on their nad-dependent dna ligase activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010532986A JP2010532986A (ja) | 2010-10-21 |
| JP2010532986A5 true JP2010532986A5 (enExample) | 2011-09-01 |
Family
ID=39790901
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010515596A Pending JP2010532986A (ja) | 2007-07-09 | 2008-07-09 | 改良された微生物の検出 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20100291564A1 (enExample) |
| EP (1) | EP2179052B1 (enExample) |
| JP (1) | JP2010532986A (enExample) |
| CN (1) | CN101849019A (enExample) |
| AU (1) | AU2008273946A1 (enExample) |
| CA (1) | CA2692800A1 (enExample) |
| MX (1) | MX2010000031A (enExample) |
| WO (1) | WO2009007719A2 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0906643D0 (en) | 2009-04-17 | 2009-06-03 | Wilson Stuart M | Detection of bacteria and fungi |
| CN103328652B (zh) | 2010-04-16 | 2016-12-28 | 宙斯科学有限公司 | 测量用于测定未纯化的样品中细胞生活力的酶活性的方法 |
| AU2013206888A1 (en) * | 2012-01-05 | 2014-08-21 | Zeus Scientific, Inc. | Improved DNA polymerase activity assays and methods enabling detection of viable microbes |
| KR20150009539A (ko) * | 2012-04-12 | 2015-01-26 | 제우스 사이언티픽, 아이엔씨. | 어떤 중합효소 연장 활성의 민감한, 정량적 측정에 유용한 중합효소 활성을 측정하고 생육성 세포의 존재를 결정하는 방법 |
| GB2528647A (en) * | 2014-07-10 | 2016-02-03 | Momentum Bioscience Ltd | Detecting viable microorganisms |
| CA2984505A1 (en) * | 2015-05-01 | 2016-11-10 | Microbial Discovery Group, Llc | Nucleic acid detection and quantification method and compositions |
| US12157690B2 (en) | 2015-12-09 | 2024-12-03 | Microbial Discovery Group Llc | Cold temperature-resistant microbials and methods of their use |
| US10335440B2 (en) | 2016-02-29 | 2019-07-02 | Microbial Discovery Group, Llc | Direct-fed microbials |
| WO2017182775A1 (en) * | 2016-04-18 | 2017-10-26 | Momentum Bioscience Limited | Microorganism detection involving filtration |
| EP3710594B1 (en) * | 2017-11-16 | 2023-07-19 | The Regents of The University of Colorado, A Body Corporate | Methods to measure functional heterogeneity among single cells |
| JP7447025B2 (ja) * | 2018-02-07 | 2024-03-11 | マイコメーター・アクティエセルスカブ | 改良した微生物バイオマス測定方法 |
| GB201805479D0 (en) | 2018-04-03 | 2018-05-16 | Momentum Bioscience Ltd | Microorganism separation and detection |
| CN113164529B (zh) | 2018-10-02 | 2024-12-24 | 微生物发现集团有限责任公司 | 用于动物的微生物 |
| CN111118181B (zh) * | 2018-10-31 | 2023-05-12 | 华东师范大学 | 一种细菌的检测方法 |
| CN114929027A (zh) | 2019-08-22 | 2022-08-19 | 微生物发现集团有限责任公司 | 用微生物菌株和抗生素的抑制方法 |
| GB201914538D0 (en) | 2019-10-08 | 2019-11-20 | Momentum Bioscience Ltd | Microorganism capture from antimicrobial-containing solution |
| CA3192065A1 (en) | 2020-08-21 | 2022-02-24 | Microbial Discovery Group, Llc | Microbials and antibiotics |
| BR112023002974A2 (pt) | 2020-08-21 | 2023-04-04 | Microbial Discovery Group Llc | Cepas microbianas e antibióticos |
| GB202405229D0 (en) | 2024-04-12 | 2024-05-29 | Momentum Bioscience Ltd | Microorganism enumeration |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4437975A (en) | 1977-07-20 | 1984-03-20 | Mobil Oil Corporation | Manufacture of lube base stock oil |
| US4931390A (en) * | 1986-04-16 | 1990-06-05 | Public Health Research Institute Of The City Of New York, Inc. | Expression of the cloned lysostaphin gene |
| IE72468B1 (en) * | 1987-07-31 | 1997-04-09 | Univ Leland Stanford Junior | Selective amplification of target polynucleotide sequences |
| KR0148265B1 (ko) | 1988-12-16 | 1998-10-15 | 에프.지이.엠 헤르만스 | 자가-지속 서열 복제 시스템 |
| DE4033752A1 (de) * | 1990-10-24 | 1992-04-30 | Reissbrodt Rolf Dr Sc Nat | Verfahren zur herstellung von lysostaphin |
| US5976806A (en) * | 1997-06-25 | 1999-11-02 | Pioneer Hi-Bred International, Inc. | DNA ligase assay |
| JP3267576B2 (ja) * | 1998-11-09 | 2002-03-18 | 三光純薬株式会社 | プローブ高分子の形成方法 |
| CA2388003C (en) * | 1999-10-19 | 2013-02-19 | Bharat Biotech International, Ltd. | Expression of recombinant mature lysostaphin |
| US6558907B2 (en) * | 2001-05-16 | 2003-05-06 | Corning Incorporated | Methods and compositions for arraying nucleic acids onto a solid support |
| WO2004067726A2 (en) | 2003-01-29 | 2004-08-12 | Keck Graduate Institute | Isothermal reactions for the amplification of oligonucleotides |
| EP1633887B1 (en) * | 2003-06-02 | 2007-04-04 | Check-Points Holding B.V. | Fast method for detecting micro-organisms in food samples |
| GB0324650D0 (en) * | 2003-10-22 | 2003-11-26 | Acolyte Biomedica Ltd | Using nucleic acids for clinical microbiology testing |
| US20070264680A1 (en) * | 2004-03-22 | 2007-11-15 | Proteus S.A. | Method and Test-Kit for the Detection and Quantification of Organisms |
| US20070009944A1 (en) * | 2005-07-01 | 2007-01-11 | University Of East Anglia | Assay for nucleic acid ligase and nucleic acid nuclease |
-
2008
- 2008-07-09 CN CN200880104327A patent/CN101849019A/zh active Pending
- 2008-07-09 WO PCT/GB2008/002354 patent/WO2009007719A2/en not_active Ceased
- 2008-07-09 US US12/667,818 patent/US20100291564A1/en not_active Abandoned
- 2008-07-09 CA CA 2692800 patent/CA2692800A1/en not_active Abandoned
- 2008-07-09 EP EP08775898A patent/EP2179052B1/en not_active Not-in-force
- 2008-07-09 MX MX2010000031A patent/MX2010000031A/es active IP Right Grant
- 2008-07-09 JP JP2010515596A patent/JP2010532986A/ja active Pending
- 2008-07-09 AU AU2008273946A patent/AU2008273946A1/en not_active Abandoned
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