JP2010531862A - パーキンソン病治療薬 - Google Patents
パーキンソン病治療薬 Download PDFInfo
- Publication number
- JP2010531862A JP2010531862A JP2010514041A JP2010514041A JP2010531862A JP 2010531862 A JP2010531862 A JP 2010531862A JP 2010514041 A JP2010514041 A JP 2010514041A JP 2010514041 A JP2010514041 A JP 2010514041A JP 2010531862 A JP2010531862 A JP 2010531862A
- Authority
- JP
- Japan
- Prior art keywords
- parkinson
- apamin
- disease
- neurons
- bee venom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
【選択図】なし
Description
Claims (4)
- パーキンソン病に罹患した患者の症状を緩和する及び/又はニューロンを再生及び/又は保護する薬剤の1週間〜6週間毎に皮下注射する単位用量を製造するための、1μg以上10μg以下の量でのアパミンの使用。
- アパミンの量が2μg以上5μg以下であることを特徴とする、請求項1に記載の使用。
- アパミンの量が3μg以上3.5μg以下であることを特徴とする、請求項1又は2に記載の使用。
- 前記アパミンがハチ毒中に含有されることを特徴とする、請求項1〜3のいずれか一項に記載の使用。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0704754A FR2918282B1 (fr) | 2007-07-02 | 2007-07-02 | Medicament pour le traitement de la maladie de parkinson |
FR0704754 | 2007-07-02 | ||
PCT/FR2008/000938 WO2009022068A2 (fr) | 2007-07-02 | 2008-07-01 | Medicament pour traiter la maladie de parkinson |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2010531862A true JP2010531862A (ja) | 2010-09-30 |
JP5517926B2 JP5517926B2 (ja) | 2014-06-11 |
Family
ID=39473255
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2010514041A Expired - Fee Related JP5517926B2 (ja) | 2007-07-02 | 2008-07-01 | パーキンソン病治療薬 |
Country Status (8)
Country | Link |
---|---|
US (1) | US8357658B2 (ja) |
EP (1) | EP2173365B1 (ja) |
JP (1) | JP5517926B2 (ja) |
DK (1) | DK2173365T3 (ja) |
ES (1) | ES2422286T3 (ja) |
FR (1) | FR2918282B1 (ja) |
PT (1) | PT2173365E (ja) |
WO (1) | WO2009022068A2 (ja) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010531861A (ja) * | 2007-07-02 | 2010-09-30 | アシスタンス プブリク−オピトウ ドゥ パリ | パーキンソン病治療薬 |
WO2017078440A1 (ko) * | 2015-11-03 | 2017-05-11 | 주식회사 젬백스앤카엘 | 신경세포 손실 예방 및 재생 효능을 가지는 펩티드 및 이를 포함하는 조성물 |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101070600B1 (ko) * | 2009-05-22 | 2011-10-06 | 주식회사 휴온스 | 봉독으로부터 분리된 봉독 정제물을 유효성분으로 포함하는 퇴행성 뇌질환의 예방 및 치료를 위한 조성물 |
FR2960780B1 (fr) * | 2010-06-07 | 2012-08-10 | Assist Publ Hopitaux De Paris | Medicament pour le traitement de la maladie de parkinson |
WO2011154887A1 (fr) * | 2010-06-07 | 2011-12-15 | Assistance Publique - Hopitaux De Paris | Méllitine pour son utilisation dans le traitement de la maladie de parkinson |
EP2788031A1 (en) | 2011-12-05 | 2014-10-15 | Key Neurosciences SAS | Composition for treating parkinson's disease. |
EP3362081B1 (en) | 2015-10-13 | 2021-12-08 | Children's National Medical Center | Treatment of learning disabilities and other neurological disorders with sk channel inhibitor(s) |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002322071A (ja) * | 2001-04-27 | 2002-11-08 | M Kim Christopher | 蜂針を用いない蜂毒療法 |
JP2010531861A (ja) * | 2007-07-02 | 2010-09-30 | アシスタンス プブリク−オピトウ ドゥ パリ | パーキンソン病治療薬 |
-
2007
- 2007-07-02 FR FR0704754A patent/FR2918282B1/fr active Active
-
2008
- 2008-07-01 ES ES08827269T patent/ES2422286T3/es active Active
- 2008-07-01 EP EP08827269.5A patent/EP2173365B1/fr not_active Not-in-force
- 2008-07-01 PT PT88272695T patent/PT2173365E/pt unknown
- 2008-07-01 DK DK08827269.5T patent/DK2173365T3/da active
- 2008-07-01 US US12/667,468 patent/US8357658B2/en active Active
- 2008-07-01 JP JP2010514041A patent/JP5517926B2/ja not_active Expired - Fee Related
- 2008-07-01 WO PCT/FR2008/000938 patent/WO2009022068A2/fr active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002322071A (ja) * | 2001-04-27 | 2002-11-08 | M Kim Christopher | 蜂針を用いない蜂毒療法 |
JP2010531861A (ja) * | 2007-07-02 | 2010-09-30 | アシスタンス プブリク−オピトウ ドゥ パリ | パーキンソン病治療薬 |
Non-Patent Citations (2)
Title |
---|
JPN5012003432; WULFF H: 'MODULATORS OF SMALL- AND INTERMEDIATE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM 以下備考' CURRENT MEDICINAL CHEMISTRY V14 N13, 200706, P1437-1457 * |
JPN6013012352; Apitherapy -- The Bee Venom Therapy , 20060722 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010531861A (ja) * | 2007-07-02 | 2010-09-30 | アシスタンス プブリク−オピトウ ドゥ パリ | パーキンソン病治療薬 |
WO2017078440A1 (ko) * | 2015-11-03 | 2017-05-11 | 주식회사 젬백스앤카엘 | 신경세포 손실 예방 및 재생 효능을 가지는 펩티드 및 이를 포함하는 조성물 |
Also Published As
Publication number | Publication date |
---|---|
DK2173365T3 (da) | 2013-07-22 |
EP2173365A2 (fr) | 2010-04-14 |
PT2173365E (pt) | 2013-08-22 |
FR2918282A1 (fr) | 2009-01-09 |
FR2918282B1 (fr) | 2009-10-02 |
WO2009022068A2 (fr) | 2009-02-19 |
US8357658B2 (en) | 2013-01-22 |
JP5517926B2 (ja) | 2014-06-11 |
WO2009022068A3 (fr) | 2009-12-17 |
ES2422286T3 (es) | 2013-09-10 |
EP2173365B1 (fr) | 2013-05-22 |
US20110009330A1 (en) | 2011-01-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP5517926B2 (ja) | パーキンソン病治療薬 | |
JP5517925B2 (ja) | パーキンソン病治療薬 | |
Won et al. | Stress, the autonomic nervous system, and the immune-kynurenine pathway in the etiology of depression | |
Langston et al. | Parkinsonism induced by 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP): implications for treatment and the pathogenesis of Parkinson’s disease | |
CA2393437A1 (en) | Exo-s-mecamylamine formulation and use in treatment | |
Koller et al. | Adjuvant therapy of parkinsonian tremor | |
KR20120050473A (ko) | 탈수초성 질환 및 다른 신경계 질환을 앓는 환자에서 신경-인지 및/또는 신경-정신 손상을 개선하기 위한 4-아미노피리딘의 용도 | |
AU2023251499A1 (en) | Combinations of opioids and N-acylethanolamines | |
JP2872809B2 (ja) | モノシアロガングリオシドgm▲下1▼またはその誘導体を含有する,パーキンソン病の治療に適する医薬組成物 | |
WO2005105120A2 (en) | Pharmaceutical combination, active on central nervous system (cns) and set of pharmaceuticals; method of treatment of cns-disorders; means facilitating penetration of the hematoencephalic barrier; pharmaceutical means for endonasal administration | |
US4355044A (en) | D-Phenylalanine treatment | |
WO2005041966A1 (en) | Treatment of parkinson's disease using apomorphine in combination with an apomorphine prodrug | |
US11439613B2 (en) | Levodopa fractionated dose composition and use | |
US6979698B1 (en) | Method of treating cognitive deficits in learning and memory | |
US4431670A (en) | D-Phenylalanine treatment | |
CN106943593A (zh) | 抗tslp抗体在制备防治慢性瘙痒药物中的应用 | |
JPH10147520A (ja) | トラマドール及びカルシウム− チャンネル拮抗物質を含有する組合せ製剤 | |
WO2008010768A1 (en) | Method of treating and diagnosing restless legs syndrome and periodic limb movements during sleep and means for carrying out the method | |
TWI233354B (en) | Nicotine antagonists for nicotine-responsive neuropsychiatric disorders | |
WO2007145874A1 (en) | Anti-nicotine treatment comprising use of three anticholinergic agents | |
Roufs | L-tyrosine in the treatment of narcolepsy | |
WO2022037006A1 (zh) | 一种止痛止痒药物组合物及其应用方法 | |
RU2659674C1 (ru) | Способ лечения цереброваскулярных нарушений головного мозга (варианты) | |
JP3381198B2 (ja) | 1,4−ジヒドロピリジンの糖尿病における使用 | |
WO2009075607A2 (en) | Pharmaceutical preparation for treating demyelinating diseases of the nervous system; preparation promoting restoration of the myelin sheath of nerve fibers; and a method for treating demyelinating diseases of the nervous system |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20110608 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20130319 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20130618 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20131029 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20140123 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20140311 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20140401 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 5517926 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
LAPS | Cancellation because of no payment of annual fees |