JP2010528583A - アミロイドβに対するヒト化抗体 - Google Patents

アミロイドβに対するヒト化抗体 Download PDF

Info

Publication number
JP2010528583A
JP2010528583A JP2009519711A JP2009519711A JP2010528583A JP 2010528583 A JP2010528583 A JP 2010528583A JP 2009519711 A JP2009519711 A JP 2009519711A JP 2009519711 A JP2009519711 A JP 2009519711A JP 2010528583 A JP2010528583 A JP 2010528583A
Authority
JP
Japan
Prior art keywords
fragment
seq
antibody
variable region
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2009519711A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010528583A5 (enExample
Inventor
アンドレア フェイファー
マリア ピルグレン
アンドレアス ムース
リャン ワッツ
Original Assignee
エーシー イミューン ソシエテ アノニム
ジェネンテック， インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by エーシー イミューン ソシエテ アノニム, ジェネンテック， インコーポレイテッド filed Critical エーシー イミューン ソシエテ アノニム
Priority claimed from PCT/US2007/073504 external-priority patent/WO2008011348A2/en
Publication of JP2010528583A publication Critical patent/JP2010528583A/ja
Publication of JP2010528583A5 publication Critical patent/JP2010528583A5/ja
Withdrawn legal-status Critical Current

Links

Images

Landscapes

  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2009519711A 2007-06-11 2007-07-13 アミロイドβに対するヒト化抗体 Withdrawn JP2010528583A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US94328907P 2007-06-11 2007-06-11
US94349907P 2007-06-12 2007-06-12
PCT/US2007/073504 WO2008011348A2 (en) 2006-07-14 2007-07-13 Humanized antibody against amyloid beta

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014026254A Division JP6076274B2 (ja) 2007-06-11 2014-02-14 アミロイドβに対するヒト化抗体

Publications (2)

Publication Number Publication Date
JP2010528583A true JP2010528583A (ja) 2010-08-26
JP2010528583A5 JP2010528583A5 (enExample) 2010-10-07

Family

ID=42767991

Family Applications (5)

Application Number Title Priority Date Filing Date
JP2009519711A Withdrawn JP2010528583A (ja) 2007-06-11 2007-07-13 アミロイドβに対するヒト化抗体
JP2014026254A Active JP6076274B2 (ja) 2007-06-11 2014-02-14 アミロイドβに対するヒト化抗体
JP2016160107A Pending JP2016202186A (ja) 2007-06-11 2016-08-17 アミロイドβに対するヒト化抗体
JP2018155243A Pending JP2019004892A (ja) 2007-06-11 2018-08-22 アミロイドβに対するヒト化抗体
JP2020124869A Pending JP2021006025A (ja) 2007-06-11 2020-07-22 アミロイドβに対するヒト化抗体

Family Applications After (4)

Application Number Title Priority Date Filing Date
JP2014026254A Active JP6076274B2 (ja) 2007-06-11 2014-02-14 アミロイドβに対するヒト化抗体
JP2016160107A Pending JP2016202186A (ja) 2007-06-11 2016-08-17 アミロイドβに対するヒト化抗体
JP2018155243A Pending JP2019004892A (ja) 2007-06-11 2018-08-22 アミロイドβに対するヒト化抗体
JP2020124869A Pending JP2021006025A (ja) 2007-06-11 2020-07-22 アミロイドβに対するヒト化抗体

Country Status (1)

Country Link
JP (5) JP2010528583A (enExample)

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991018983A1 (de) * 1990-05-29 1991-12-12 Alois Jungbauer Komplexes virales antigen von hiv-1 bindendes rekombinantes protein
US5837822A (en) * 1992-01-27 1998-11-17 Icos Corporation Humanized antibodies specific for ICAM related protein
WO1999027944A1 (en) * 1997-12-02 1999-06-10 Neuralab Limited Prevention and treatment of amyloidogenic disease
JP2003523764A (ja) * 2000-02-24 2003-08-12 ワシントン・ユニバーシティ Ａβペプチドを隔離するヒト化抗体
JP2004500354A (ja) * 1999-11-29 2004-01-08 ニューロケム　インコーポレーティッド 全ｄ体ペプチドを含む、アルツハイマー病およびアミロイド関連疾患の予防および処置のためのワクチン
JP2005527199A (ja) * 2002-02-20 2005-09-15 エフ．ホフマン−ラ　ロシュ　アーゲー 抗Ａβ抗体とその利用法
WO2006014478A1 (en) * 2004-07-02 2006-02-09 Northwestern University MONOLOCAL ANTIBODIES THAT TARGET PATHOLOGICAL ASSEMBLIES OF AMYLOID β (ABETA)
WO2006029879A2 (en) * 2004-09-17 2006-03-23 F.Hoffmann-La Roche Ag Anti-ox40l antibodies
WO2006066171A1 (en) * 2004-12-15 2006-06-22 Neuralab Limited Amyloid βετα antibodies for use in improving cognition
WO2006138737A2 (en) * 2005-06-17 2006-12-28 Elan Pharma International Limited Methods of purifying anti a beta antibodies

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1461359T3 (da) * 2002-01-18 2007-07-09 Pf Medicament Hidtil ukendte anti-IGF-IR-antistoffer og anvendelser deraf
SG10201706600VA (en) * 2005-11-30 2017-09-28 Abbvie Inc Monoclonal antibodies and uses thereof
US20090232801A1 (en) * 2007-05-30 2009-09-17 Abbot Laboratories Humanized Antibodies Which Bind To AB (1-42) Globulomer And Uses Thereof

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991018983A1 (de) * 1990-05-29 1991-12-12 Alois Jungbauer Komplexes virales antigen von hiv-1 bindendes rekombinantes protein
US5837822A (en) * 1992-01-27 1998-11-17 Icos Corporation Humanized antibodies specific for ICAM related protein
WO1999027944A1 (en) * 1997-12-02 1999-06-10 Neuralab Limited Prevention and treatment of amyloidogenic disease
JP2004500354A (ja) * 1999-11-29 2004-01-08 ニューロケム　インコーポレーティッド 全ｄ体ペプチドを含む、アルツハイマー病およびアミロイド関連疾患の予防および処置のためのワクチン
JP2003523764A (ja) * 2000-02-24 2003-08-12 ワシントン・ユニバーシティ Ａβペプチドを隔離するヒト化抗体
JP2005527199A (ja) * 2002-02-20 2005-09-15 エフ．ホフマン−ラ　ロシュ　アーゲー 抗Ａβ抗体とその利用法
WO2006014478A1 (en) * 2004-07-02 2006-02-09 Northwestern University MONOLOCAL ANTIBODIES THAT TARGET PATHOLOGICAL ASSEMBLIES OF AMYLOID β (ABETA)
WO2006029879A2 (en) * 2004-09-17 2006-03-23 F.Hoffmann-La Roche Ag Anti-ox40l antibodies
WO2006066171A1 (en) * 2004-12-15 2006-06-22 Neuralab Limited Amyloid βετα antibodies for use in improving cognition
WO2006138737A2 (en) * 2005-06-17 2006-12-28 Elan Pharma International Limited Methods of purifying anti a beta antibodies

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JPN6012038284; ＰＮＡＳ Ｖｏｌ．１００，　Ｎｏ．４, 2003, ｐｐ．２０２３-２０２８ *
JPN6012038286; Ｂｉｏｃｈｅｍｉｓｔｒｙ Ｖｏｌ．４３, 2004, ｐｐ．６９５９-６９６７ *
JPN6012038288; ＰＮＡＳ Ｖｏｌ．９３, 1996, ｐｐ．４５２-４５５ *

Also Published As

Publication number Publication date
JP2016202186A (ja) 2016-12-08
JP6076274B2 (ja) 2017-02-08
JP2019004892A (ja) 2019-01-17
JP2021006025A (ja) 2021-01-21
JP2014168460A (ja) 2014-09-18

Similar Documents

Publication Publication Date Title
JP5641737B2 (ja) アミロイドβに対するヒト化抗体
JP5898715B2 (ja) アミロイドβに対するヒト化抗体
JP2018095647A (ja) アミロイドβに対するヒト化抗体
US20220227847A1 (en) Humanized antibody
JP6076274B2 (ja) アミロイドβに対するヒト化抗体
AU2013202799C1 (en) Humanized antibody against amyloid beta
JP2022070853A (ja) アミロイドβに対するヒト化抗体
US20210317197A1 (en) Humanized antibody
EP3988566A1 (en) Humanized antibody against amyloid beta
HK1239710B (zh) 针对淀粉状蛋白β的人源化抗体
HK1239710A1 (en) Humanized antibody against amyloid beta
HK1194083B (en) Humanized antibody against amyloid beta
HK1194083A (en) Humanized antibody against amyloid beta
HK1172352A (en) Humanized antibody against amyloid beta
HK1139154B (en) Humani zed antibody against amyloid beta

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100709

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20100709

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20120723

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20121019

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20121026

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20130122

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20130123

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20131016

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140214

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140224

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140327

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20140402

A912 Re-examination (zenchi) completed and case transferred to appeal board

Free format text: JAPANESE INTERMEDIATE CODE: A912

Effective date: 20140425

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20150324

A761 Written withdrawal of application

Free format text: JAPANESE INTERMEDIATE CODE: A761

Effective date: 20150813