JP2010526183A5 - - Google Patents

Download PDF

Info

Publication number
JP2010526183A5
JP2010526183A5 JP2010506606A JP2010506606A JP2010526183A5 JP 2010526183 A5 JP2010526183 A5 JP 2010526183A5 JP 2010506606 A JP2010506606 A JP 2010506606A JP 2010506606 A JP2010506606 A JP 2010506606A JP 2010526183 A5 JP2010526183 A5 JP 2010526183A5
Authority
JP
Japan
Prior art keywords
nitrogen
oxygen
sulfur
partially unsaturated
independently selected
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2010506606A
Other languages
English (en)
Japanese (ja)
Other versions
JP5403826B2 (ja
JP2010526183A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2008/062033 external-priority patent/WO2008134731A1/en
Publication of JP2010526183A publication Critical patent/JP2010526183A/ja
Publication of JP2010526183A5 publication Critical patent/JP2010526183A5/ja
Application granted granted Critical
Publication of JP5403826B2 publication Critical patent/JP5403826B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2010506606A 2007-04-30 2008-04-30 疎水性薬物のカプセル化のために混合立体化学を有するハイブリッドブロックコポリマー Expired - Fee Related JP5403826B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US91495807P 2007-04-30 2007-04-30
US60/914,958 2007-04-30
PCT/US2008/062033 WO2008134731A1 (en) 2007-04-30 2008-04-30 Hybrid block copolymer micelles with mixed stereochemistry for encapsulation of hydrophobic agents

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013140782A Division JP2013199657A (ja) 2007-04-30 2013-07-04 疎水性薬物のカプセル化のために混合立体化学を有するハイブリッドブロックコポリマー

Publications (3)

Publication Number Publication Date
JP2010526183A JP2010526183A (ja) 2010-07-29
JP2010526183A5 true JP2010526183A5 (cg-RX-API-DMAC7.html) 2012-03-08
JP5403826B2 JP5403826B2 (ja) 2014-01-29

Family

ID=39586942

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2010506606A Expired - Fee Related JP5403826B2 (ja) 2007-04-30 2008-04-30 疎水性薬物のカプセル化のために混合立体化学を有するハイブリッドブロックコポリマー
JP2013140782A Withdrawn JP2013199657A (ja) 2007-04-30 2013-07-04 疎水性薬物のカプセル化のために混合立体化学を有するハイブリッドブロックコポリマー

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2013140782A Withdrawn JP2013199657A (ja) 2007-04-30 2013-07-04 疎水性薬物のカプセル化のために混合立体化学を有するハイブリッドブロックコポリマー

Country Status (13)

Country Link
US (3) US7799339B2 (cg-RX-API-DMAC7.html)
EP (2) EP2359862B1 (cg-RX-API-DMAC7.html)
JP (2) JP5403826B2 (cg-RX-API-DMAC7.html)
KR (1) KR101697363B1 (cg-RX-API-DMAC7.html)
AT (1) ATE485840T1 (cg-RX-API-DMAC7.html)
AU (1) AU2008245404B2 (cg-RX-API-DMAC7.html)
CA (1) CA2685350C (cg-RX-API-DMAC7.html)
DE (1) DE602008003183D1 (cg-RX-API-DMAC7.html)
ES (2) ES2432641T3 (cg-RX-API-DMAC7.html)
IL (1) IL201839A (cg-RX-API-DMAC7.html)
MX (1) MX2009011479A (cg-RX-API-DMAC7.html)
NZ (2) NZ580605A (cg-RX-API-DMAC7.html)
WO (1) WO2008134731A1 (cg-RX-API-DMAC7.html)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2650035C (en) 2006-04-27 2015-02-03 Intezyne Technologies, Inc. Poly (ethylene glycol) containing chemically disparate endgroups
US8258190B2 (en) * 2007-04-30 2012-09-04 Intezyne Technologies, Inc. Encapsulated contrast agents
EP2359862B1 (en) * 2007-04-30 2013-07-24 Intezyne Technologies Inc. Hybrid block copolymer micelles with mixed stereochemistry for encapsulation of hydrophobic agents
EP2217281A2 (en) * 2007-11-07 2010-08-18 Mallinckrodt Inc. Photonic shell-core cross linked and functionalized nanostructures for biological applications
US20090286938A1 (en) * 2008-04-30 2009-11-19 Intezyne Technologies, Inc. Synthesis of hybrid block copolymers from difluoroacetate ammonium salts
CN101869712B (zh) * 2009-04-21 2016-01-20 财团法人工业技术研究院 使用包囊抗肿瘤药物的聚合胶束用于治疗肿瘤的药物组合物
GB0907251D0 (en) * 2009-04-28 2009-06-10 Univ Leiden Coplymers
US8524784B2 (en) 2009-04-30 2013-09-03 Intezyne Technologies, Incorporated Polymer micelles containing anthracylines for the treatment of cancer
US8524783B2 (en) 2009-04-30 2013-09-03 Intezyne Technologies, Incorporated Polymer micelles containing anthracylines for the treatment of cancer
MX2011011730A (es) * 2009-05-04 2011-12-08 Intezyne Technologies Inc Micelas polimericas que contienen sn-38 para el tratamiento de cancer.
CA2799468A1 (en) 2010-05-14 2011-11-17 Mallinckrodt Llc Functional, cross-linked nanostructures for tandem optical imaging and therapy
EP2609935B1 (en) * 2010-08-23 2018-10-10 Shimadzu Corporation Switching fluorescent nanoparticle probe and fluorescent particle imaging method using same
WO2012058552A1 (en) * 2010-10-29 2012-05-03 Intezyne Technologies, Incorporated Iron stabilized polymer micelles for drug delivery applications
WO2012097133A2 (en) * 2011-01-12 2012-07-19 H. Lee Moffitt Cancer Center And Research Institute, Inc. Compounds and methods for inducing apoptosis in cancer cells using a bh3 alpha-helical mimetic
GB2488788B (en) * 2011-03-07 2013-07-10 Natco Pharma Ltd Oral formulation of phenylaminopyrymidine compound with enhanced bioavailability and pharmacological response
CN103501821A (zh) * 2011-03-08 2014-01-08 艾克塞斯制药公司 用于递送活性剂穿过生物膜的靶向纳米载体系统
US9592302B2 (en) * 2011-05-23 2017-03-14 University Of Massachusetts Crosslinked polymer nano-assemblies and uses thereof
US8609146B2 (en) 2011-09-19 2013-12-17 Intezyne Technologies, Inc. Multi-block copolymers for the preparation of stabilized micelles
CN102408561B (zh) * 2011-11-14 2013-03-27 中国科学院长春应用化学研究所 一种嵌段共聚物、其制备方法及温度敏感型水凝胶
WO2013151537A1 (en) * 2012-04-03 2013-10-10 Empire Technology Development Llc Biocompatible adhesive polymers
US20140127271A1 (en) * 2012-04-11 2014-05-08 Intezyne Technologies, Inc. Block copolymers for stable micelles
AU2014256366B2 (en) * 2012-04-11 2016-12-08 Intezyne Technologies, Inc. Block copolymers for stable micelles
MX340992B (es) * 2012-04-11 2016-08-03 Intezyne Tech Inc Copolimeros de bloque para micelas estables.
US9944752B2 (en) 2012-04-11 2018-04-17 Intezyne Technologies, Inc. Block copolymers for stable micelles
AU2016250403B2 (en) * 2012-04-11 2018-12-06 Intezyne Technologies, Inc Block copolymers for stable micelles
US20140114051A1 (en) * 2012-04-11 2014-04-24 Intezyne Technologies, Inc. Block copolymers for stable micelles
US20140113879A1 (en) * 2012-04-11 2014-04-24 Intezyne Technologies, Inc. Block copolymers for stable micelles
US10137081B2 (en) 2012-09-28 2018-11-27 Delpor, Inc. Device and method for sustained release of antipsychotic medications
TWI454450B (zh) 2012-11-02 2014-10-01 Ind Tech Res Inst 有機化合物及包含其之有機電激發光裝置
CN103304802B (zh) * 2013-05-28 2015-04-22 上海交通大学 酸敏感两亲性嵌段共聚物及其制备、用途
US20160129117A1 (en) * 2013-07-03 2016-05-12 Nippon Kayaku Kabushiki Kaisha Novel Boronic Acid Compound Preparation
CN103709410B (zh) * 2013-12-03 2016-04-13 上海交通大学 酸敏感两亲性嵌段共聚物及其自组织胶束、用途
CN104856952B (zh) * 2015-05-13 2017-08-04 江南大学 一种聚(L‑谷氨酸)‑b‑聚乙二醇载药纳米胶束的制备
JPWO2017043653A1 (ja) * 2015-09-11 2018-06-28 国立大学法人 東京大学 タンパク質を安定化するための化合物
US10143689B2 (en) 2017-02-08 2018-12-04 Interzyne Technologies, Inc. SN-38 loaded iron crosslinked micelle and methods thereof
CN107224589B (zh) * 2017-05-08 2021-03-26 中山大学 一种输送抗体用于肿瘤免疫治疗的mr成像聚合物胶束及其制备方法
CN108376608B (zh) * 2018-02-10 2020-11-06 青岛大学 一种磁性纳米粒子及其制备磁性固相载体的用途
US12435048B2 (en) 2018-09-28 2025-10-07 Lonza Ltd Method for preparation of n-carboxyanhydrides
CN109044972A (zh) * 2018-10-25 2018-12-21 宁夏医科大学 共载紫杉醇的辣椒素前药聚合物胶束及其制备方法
IL294481B1 (en) * 2020-01-10 2025-10-01 Tyndall Formulation Services Llc Polymeric excipients for drug delivery applications
US10918619B1 (en) 2020-01-10 2021-02-16 Tyndall Formulation Services, LLC Formulations of paclitaxel with poly(amino acid) block polymers
WO2021141605A1 (en) * 2020-01-10 2021-07-15 Tyndall Formulation Services, LLC Formulations of paclitaxel with poly(amino acid) block polymers
EP4087535A1 (en) * 2020-01-10 2022-11-16 Tyndall Formulation Services, LLC Formulations of sn-38 with poly(amino acid) block polymers
US11286344B2 (en) 2020-01-10 2022-03-29 Tyndall Formulation Services, LLC Polymer excipients for drug delivery applications
EP4087545A1 (en) 2020-01-10 2022-11-16 R-Pharm US Operating LLC Compositions of ixabepilone
US10836869B1 (en) 2020-01-10 2020-11-17 Tyndall Formulation Services, LLC Polymer excipients for drug delivery applications
KR102219317B1 (ko) * 2020-10-06 2021-02-24 엘앤피코스메틱 (주) 천연 보습인자를 이용하여 형성된 미셀 복합체를 포함하는 화장료 조성물의 제조방법 및 이로부터 제조된 화장료 조성물
WO2025039009A1 (en) * 2023-08-17 2025-02-20 Cornell University Porous functionalized multiblock copolymer films, methods of making and using same, and products thereof

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5650270A (en) * 1982-02-01 1997-07-22 Northeastern University Molecular analytical release tags and their use in chemical analysis
US4650750A (en) * 1982-02-01 1987-03-17 Giese Roger W Method of chemical analysis employing molecular release tag compounds
US4709016A (en) * 1982-02-01 1987-11-24 Northeastern University Molecular analytical release tags and their use in chemical analysis
US5516931A (en) * 1982-02-01 1996-05-14 Northeastern University Release tag compounds producing ketone signal groups
KR940003548U (ko) * 1992-08-14 1994-02-21 김형술 세탁물 건조기
DK1329221T3 (da) * 2000-09-26 2006-10-23 Toudai Tlo Ltd Polymer micelle med indesluttet cisplatin og anvendelse deraf
JP2003267876A (ja) * 2002-03-15 2003-09-25 Nippon Kayaku Co Ltd 新規な血管狭窄治療剤又は予防剤
JP4535229B2 (ja) * 2003-05-08 2010-09-01 国立大学法人 東京大学 ポリエチレングリコール−ポリカチオンブロック共重合体
EP2502941A1 (en) 2004-10-25 2012-09-26 Intezyne Technologies Inc. Heterobifunctional poly (ethylene glycol) and uses thereof
EP1833958A4 (en) * 2005-01-04 2009-01-14 Intezyne Technologies Inc SYNTHESIS OF HYBRID BLOCK COPOLYMERS AND USES THEREOF
CA2597378A1 (en) * 2005-02-11 2006-08-17 Intezyne Technologies, Incorporated Synthesis of homopolymers and block copolymers
NZ562064A (en) * 2005-04-01 2011-03-31 Intezyne Technologies Inc Polymeric micelles for drug delivery
BRPI0616877A2 (pt) * 2005-10-05 2011-07-05 Tokyo Cro Inc copolìmero em bloco biocompatìvel, micela, particulado, compósito, composição farmacêutica, método para fabricar uma micela, particulado ou compósito, e, uso de um copolìmero em bloco biocompatìvel
CA2650035C (en) * 2006-04-27 2015-02-03 Intezyne Technologies, Inc. Poly (ethylene glycol) containing chemically disparate endgroups
EP2359862B1 (en) * 2007-04-30 2013-07-24 Intezyne Technologies Inc. Hybrid block copolymer micelles with mixed stereochemistry for encapsulation of hydrophobic agents

Similar Documents

Publication Publication Date Title
JP2010526183A5 (cg-RX-API-DMAC7.html)
CN115197078B (zh) 一种聚乙二醇化脂质及其修饰的脂质体、含该脂质体的药物组合物及其制剂和应用
JP5403826B2 (ja) 疎水性薬物のカプセル化のために混合立体化学を有するハイブリッドブロックコポリマー
JP4390845B2 (ja) 薬物送達のためのポリマーミセル
US10064954B2 (en) Polymer-cyclodextrin-lipid conjugates
AU2005251403B2 (en) Cationic lipids and methods of use
US8153110B2 (en) Environment-responding siRNA carrier using disulfide-cross-linked polymeric micelle
US20100145018A1 (en) Lipid-Polymer-Conjugates
CN104704023A (zh) 聚合物-碳水化合物-脂质缀合物
Ramireddy et al. Stimuli sensitive amphiphilic dendrimers
JP2008537943A5 (cg-RX-API-DMAC7.html)
NZ581166A (en) Polyethyleneglycol-modified lipid compounds and uses thereof
JP2015214584A (ja) 安定なミセルのためのブロックコポリマー
JP2011503067A (ja) 生物学的適用のためのフォトニックシェルコアが架橋し、官能化されたナノ構造
JP2020522534A (ja) カルニチン由来材料に関する方法および組成物
CN115515925A (zh) 一种聚乙二醇化脂质及其修饰的脂质体、含该脂质体的药物组合物及其制剂和应用
US20220162382A1 (en) Production of nanoparticles and microparticles
JP2022160543A (ja) アミノチオール及びその類似体の改善された保護及び送達のための方法
FR2915684A1 (fr) Particules a base de polyelectrolytes et de principe actif a liberation modifiee et formulations pharmaceutiques contenant ces particules
JP2022024207A (ja) ポリアミノ酸、ブロックコポリマー及びポリマー粒子組成物
Xiong et al. PEO-modified poly (L-amino acid) micelles for drug delivery
Heffernan et al. Cross-Linked Micelles for Vaccine Delivery
Kim Synthesis and performance of molecules for protein crystallization and drug & gene delivery
CN115135694A (zh) 用于药物递送应用的聚合物赋形剂
AU2011253734A1 (en) Cationic lipids and methods of use