JP2010522624A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2010522624A5 JP2010522624A5 JP2010501217A JP2010501217A JP2010522624A5 JP 2010522624 A5 JP2010522624 A5 JP 2010522624A5 JP 2010501217 A JP2010501217 A JP 2010501217A JP 2010501217 A JP2010501217 A JP 2010501217A JP 2010522624 A5 JP2010522624 A5 JP 2010522624A5
- Authority
- JP
- Japan
- Prior art keywords
- polymer
- component
- medical device
- layer
- bioerodible
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229920000642 polymer Polymers 0.000 claims 23
- 239000010410 layer Substances 0.000 claims 20
- 229920006125 amorphous polymer Polymers 0.000 claims 16
- 229920013641 bioerodible polymer Polymers 0.000 claims 16
- 239000000178 monomer Substances 0.000 claims 15
- 239000003814 drug Substances 0.000 claims 10
- 229940124597 therapeutic agent Drugs 0.000 claims 9
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims 8
- JVTAAEKCZFNVCJ-REOHCLBHSA-N L-lactic acid Chemical compound C[C@H](O)C(O)=O JVTAAEKCZFNVCJ-REOHCLBHSA-N 0.000 claims 4
- 235000014655 lactic acid Nutrition 0.000 claims 4
- 239000004310 lactic acid Substances 0.000 claims 4
- 239000000758 substrate Substances 0.000 claims 4
- 230000001225 therapeutic effect Effects 0.000 claims 3
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Chemical compound OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 claims 2
- 229920005689 PLLA-PGA Polymers 0.000 claims 2
- 239000003146 anticoagulant agent Substances 0.000 claims 2
- 229920000229 biodegradable polyester Polymers 0.000 claims 2
- 239000004622 biodegradable polyester Substances 0.000 claims 2
- 230000010261 cell growth Effects 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 239000013047 polymeric layer Substances 0.000 claims 2
- 230000002792 vascular Effects 0.000 claims 2
- 210000005167 vascular cell Anatomy 0.000 claims 2
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 claims 1
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 claims 1
- 229920001244 Poly(D,L-lactide) Polymers 0.000 claims 1
- 229940035674 anesthetics Drugs 0.000 claims 1
- 230000003110 anti-inflammatory effect Effects 0.000 claims 1
- 230000002095 anti-migrative effect Effects 0.000 claims 1
- 230000002927 anti-mitotic effect Effects 0.000 claims 1
- 230000000118 anti-neoplastic effect Effects 0.000 claims 1
- 230000001028 anti-proliverative effect Effects 0.000 claims 1
- 230000002785 anti-thrombosis Effects 0.000 claims 1
- 239000003529 anticholesteremic agent Substances 0.000 claims 1
- 229940127226 anticholesterol agent Drugs 0.000 claims 1
- 229940127219 anticoagulant drug Drugs 0.000 claims 1
- 239000003080 antimitotic agent Substances 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 229940034982 antineoplastic agent Drugs 0.000 claims 1
- 229920002988 biodegradable polymer Polymers 0.000 claims 1
- 239000004621 biodegradable polymer Substances 0.000 claims 1
- 229920001577 copolymer Polymers 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 210000002744 extracellular matrix Anatomy 0.000 claims 1
- 239000003193 general anesthetic agent Substances 0.000 claims 1
- 239000003966 growth inhibitor Substances 0.000 claims 1
- 239000007952 growth promoter Substances 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 239000002184 metal Substances 0.000 claims 1
- 230000008520 organization Effects 0.000 claims 1
- 229940124549 vasodilator Drugs 0.000 claims 1
- 239000003071 vasodilator agent Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92039407P | 2007-03-28 | 2007-03-28 | |
| PCT/US2008/058407 WO2008121702A2 (en) | 2007-03-28 | 2008-03-27 | Medical devices having bioerodable layers for the release of therapeutic agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010522624A JP2010522624A (ja) | 2010-07-08 |
| JP2010522624A5 true JP2010522624A5 (cg-RX-API-DMAC7.html) | 2011-05-19 |
Family
ID=39808861
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010501217A Pending JP2010522624A (ja) | 2007-03-28 | 2008-03-27 | 治療剤の放出のための生体侵食性層を有する医療装置 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20090074838A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2134380A2 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2010522624A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2008121702A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8057876B2 (en) * | 2008-02-25 | 2011-11-15 | Abbott Cardiovascular Systems Inc. | Bioabsorbable stent with layers having different degradation rates |
| WO2011019952A1 (en) * | 2009-08-13 | 2011-02-17 | Boston Scientific Scimed, Inc. | Polymers having lipophilic hydrocarbon and biodegradable polymeric segments |
| US8685433B2 (en) * | 2010-03-31 | 2014-04-01 | Abbott Cardiovascular Systems Inc. | Absorbable coating for implantable device |
| US9907640B2 (en) * | 2013-06-21 | 2018-03-06 | Boston Scientific Scimed, Inc. | Stent with deflecting connector |
| CN104587534A (zh) * | 2013-10-31 | 2015-05-06 | 先健科技(深圳)有限公司 | 可吸收铁基合金支架 |
| CN103933620B (zh) * | 2014-04-09 | 2015-09-16 | 北京颐合恒瑞医疗科技有限公司 | 一种可吸收皮肤缝合钉及制备方法 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5811447A (en) * | 1993-01-28 | 1998-09-22 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US5464450A (en) * | 1991-10-04 | 1995-11-07 | Scimed Lifesystems Inc. | Biodegradable drug delivery vascular stent |
| US6663881B2 (en) * | 1993-01-28 | 2003-12-16 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US5824048A (en) * | 1993-04-26 | 1998-10-20 | Medtronic, Inc. | Method for delivering a therapeutic substance to a body lumen |
| DE19608423A1 (de) * | 1996-03-05 | 1997-09-11 | Merck Patent Gmbh | Implantate mit phasenweiser Arzneistoffabgabe |
| WO1998056312A1 (en) * | 1997-06-13 | 1998-12-17 | Scimed Life Systems, Inc. | Stents having multiple layers of biodegradable polymeric composition |
| US6368658B1 (en) * | 1999-04-19 | 2002-04-09 | Scimed Life Systems, Inc. | Coating medical devices using air suspension |
| US6258121B1 (en) * | 1999-07-02 | 2001-07-10 | Scimed Life Systems, Inc. | Stent coating |
| US6338739B1 (en) * | 1999-12-22 | 2002-01-15 | Ethicon, Inc. | Biodegradable stent |
| US6545097B2 (en) * | 2000-12-12 | 2003-04-08 | Scimed Life Systems, Inc. | Drug delivery compositions and medical devices containing block copolymer |
| US20040220660A1 (en) * | 2001-02-05 | 2004-11-04 | Shanley John F. | Bioresorbable stent with beneficial agent reservoirs |
| US20030050687A1 (en) * | 2001-07-03 | 2003-03-13 | Schwade Nathan D. | Biocompatible stents and method of deployment |
| JP2005525911A (ja) * | 2002-05-20 | 2005-09-02 | オーバス メディカル テクノロジーズ インク． | 移植可能な薬物溶出医療用デバイス |
| US20070078513A1 (en) * | 2002-09-18 | 2007-04-05 | Medtronic Vascular, Inc. | Controllable drug releasing gradient coatings for medical devices |
| KR20060028695A (ko) * | 2003-06-16 | 2006-03-31 | 난양 테크놀러지컬 유니버시티 | 고분자 스텐트 및 이의 제조 방법 |
| TW200539841A (en) * | 2004-03-10 | 2005-12-16 | Orbus Medical Technologies Inc | Progenitor endothelial cell capturing with a drug eluting implantable medical device |
| US20080124400A1 (en) * | 2004-06-24 | 2008-05-29 | Angiotech International Ag | Microparticles With High Loadings Of A Bioactive Agent |
| WO2006027994A1 (ja) * | 2004-09-08 | 2006-03-16 | Kaneka Corporation | 生体留置用ステント |
| WO2006080630A1 (en) * | 2004-09-23 | 2006-08-03 | Handok Pharmaceuticals Co., Ltd. | Pharmaceutical combination preparation for oral delivery for the treatment of diabetes mellitus |
| US20060147491A1 (en) * | 2005-01-05 | 2006-07-06 | Dewitt David M | Biodegradable coating compositions including multiple layers |
| US20060198868A1 (en) * | 2005-01-05 | 2006-09-07 | Dewitt David M | Biodegradable coating compositions comprising blends |
| US8075906B2 (en) * | 2005-02-01 | 2011-12-13 | Boston Scientific Scimed, Inc. | Medical devices having polymeric regions with copolymers containing hydrocarbon and heteroatom-containing monomeric species |
| EP3339348B1 (en) * | 2005-04-22 | 2019-12-04 | Université de Genève | Polylactide compositions and uses thereof |
| US8778375B2 (en) * | 2005-04-29 | 2014-07-15 | Advanced Cardiovascular Systems, Inc. | Amorphous poly(D,L-lactide) coating |
| US9248219B2 (en) * | 2007-09-14 | 2016-02-02 | Boston Scientific Scimed, Inc. | Medical devices having bioerodable layers for the release of therapeutic agents |
-
2008
- 2008-03-27 WO PCT/US2008/058407 patent/WO2008121702A2/en not_active Ceased
- 2008-03-27 JP JP2010501217A patent/JP2010522624A/ja active Pending
- 2008-03-27 EP EP08732921A patent/EP2134380A2/en not_active Withdrawn
- 2008-03-27 US US12/056,689 patent/US20090074838A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2010522624A5 (cg-RX-API-DMAC7.html) | ||
| Tesfamariam | Bioresorbable vascular scaffolds: Biodegradation, drug delivery and vascular remodeling | |
| US9180228B2 (en) | Rubber toughened bioresorbable polymer peripheral scaffolds | |
| US9066992B2 (en) | Polymers for implantable devices exhibiting shape-memory effects | |
| US9089412B2 (en) | Multilayer bioabsorbable scaffolds and methods of fabricating | |
| US10392472B2 (en) | Biodegradable cross-linked polymer and methods of preparing the same | |
| JP2009522071A (ja) | 生体吸収性の薬物運搬デバイス | |
| JP6667758B2 (ja) | 生体吸収性ステント | |
| CN1812754A (zh) | 聚合物支架和其制造方法 | |
| JP2012514121A5 (cg-RX-API-DMAC7.html) | ||
| WO2007101443A8 (en) | Degradable hydrophilic block copolymers with improved biocompatibility for soft tissue regeneration | |
| JP2011509156A5 (cg-RX-API-DMAC7.html) | ||
| US20200108182A1 (en) | Self-expandable stent and method of producing the same | |
| JP2009522070A (ja) | 溶媒キャストチューブを有する生体吸収性の薬物運搬デバイスの製法 | |
| CN105025945B (zh) | 用于外周动脉疾病的药物递送装置 | |
| US20170319363A1 (en) | High molecular weight polylactide and polycaprolactone copolymer and blends for bioresorbable vascular scaffolds | |
| US9610387B2 (en) | Plasticizers for a biodegradable scaffolding and methods of forming same | |
| US20150305899A1 (en) | Branched polyhydroxyalkanoate systems for bioresorbable vascular scaffold applications | |
| CN111601625B (zh) | 自膨型支架及其制造方法 | |
| US20110223232A1 (en) | drug-release composition having a therapeutic carrier | |
| US20080014170A1 (en) | Drug delivery polyanhydride composition and method | |
| JP2009522069A (ja) | 溶媒キャストフィルムを有する生体吸収性の薬物運搬デバイスの製法 | |
| Fan et al. | Metallic stents coated with bioabsorbable polymers |