JP2010522550A5 - - Google Patents
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- Publication number
- JP2010522550A5 JP2010522550A5 JP2010500296A JP2010500296A JP2010522550A5 JP 2010522550 A5 JP2010522550 A5 JP 2010522550A5 JP 2010500296 A JP2010500296 A JP 2010500296A JP 2010500296 A JP2010500296 A JP 2010500296A JP 2010522550 A5 JP2010522550 A5 JP 2010522550A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- acid according
- cell epitope
- light chain
- heavy chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000007523 nucleic acids Chemical class 0.000 claims 29
- 102000039446 nucleic acids Human genes 0.000 claims 29
- 108020004707 nucleic acids Proteins 0.000 claims 29
- 210000001744 T-lymphocyte Anatomy 0.000 claims 12
- 108060003951 Immunoglobulin Proteins 0.000 claims 5
- 102000018358 immunoglobulin Human genes 0.000 claims 5
- 108010047041 Complementarity Determining Regions Proteins 0.000 claims 3
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 claims 3
- 210000002443 helper t lymphocyte Anatomy 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 2
- 230000028993 immune response Effects 0.000 claims 2
- 230000035772 mutation Effects 0.000 claims 2
- 230000004936 stimulating effect Effects 0.000 claims 2
- 239000002671 adjuvant Substances 0.000 claims 1
- 210000004443 dendritic cell Anatomy 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 210000002510 keratinocyte Anatomy 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0706070.0 | 2007-03-28 | ||
| GBGB0706070.0A GB0706070D0 (en) | 2007-03-28 | 2007-03-28 | Nucleic acids |
| PCT/EP2008/053761 WO2008116937A2 (en) | 2007-03-28 | 2008-03-28 | Nucleic acids |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010522550A JP2010522550A (ja) | 2010-07-08 |
| JP2010522550A5 true JP2010522550A5 (OSRAM) | 2011-02-24 |
| JP5415399B2 JP5415399B2 (ja) | 2014-02-12 |
Family
ID=38050410
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010500296A Active JP5415399B2 (ja) | 2007-03-28 | 2008-03-28 | 核酸 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US8742088B2 (OSRAM) |
| EP (2) | EP2193803B1 (OSRAM) |
| JP (1) | JP5415399B2 (OSRAM) |
| KR (4) | KR20170040387A (OSRAM) |
| CN (2) | CN101678092B (OSRAM) |
| AT (1) | ATE529128T1 (OSRAM) |
| AU (1) | AU2008231723B2 (OSRAM) |
| BR (1) | BRPI0808599A2 (OSRAM) |
| CA (1) | CA2681531C (OSRAM) |
| DK (2) | DK2193803T3 (OSRAM) |
| ES (2) | ES2638188T3 (OSRAM) |
| GB (1) | GB0706070D0 (OSRAM) |
| PL (1) | PL2134357T3 (OSRAM) |
| PT (2) | PT2134357T (OSRAM) |
| WO (1) | WO2008116937A2 (OSRAM) |
| ZA (1) | ZA200907242B (OSRAM) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0706070D0 (en) | 2007-03-28 | 2007-05-09 | Scancell Ltd | Nucleic acids |
| GB201214007D0 (en) | 2012-08-07 | 2012-09-19 | Scancell Ltd | Anti-tumour immune responses to modified self-epitopes |
| EP3253419A1 (en) | 2015-02-02 | 2017-12-13 | The University of Birmingham | Targeting moiety peptide epitope complexes having a plurality of t-cell epitopes |
| WO2017210149A1 (en) * | 2016-05-31 | 2017-12-07 | Igc Bio, Inc. | Compositions and methods for generating an antibody library |
| US11419928B2 (en) | 2017-10-25 | 2022-08-23 | The Johns Hopkins University | Methods and compositions for treating cancer |
| GB201815041D0 (en) | 2018-09-14 | 2018-10-31 | Scancell Ltd | Epitopes |
| WO2021195089A1 (en) | 2020-03-23 | 2021-09-30 | Sorrento Therapeutics, Inc. | Fc-coronavirus antigen fusion proteins, and nucleic acids, vectors, compositions and methods of use thereof |
| CN111423504B (zh) * | 2020-04-17 | 2021-03-26 | 安徽高安生物医学科技有限公司 | 黑色素瘤特异性抗原肽、肽复合物以及人工抗原呈递细胞 |
| KR20230058081A (ko) | 2020-08-26 | 2023-05-02 | 스캔셀 리미티드 | 인간 IgG1의 변형된 FC 영역과 적어도 하나의 이종 항원을 포함하는 폴리펩티드를 암호화하는 핵산 |
| GB202314361D0 (en) * | 2023-09-19 | 2023-11-01 | Scancell Ltd | Vaccine compositions and uses thereof |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| US5969109A (en) * | 1990-02-28 | 1999-10-19 | Bona; Constantin | Chimeric antibodies comprising antigen binding sites and B and T cell epitopes |
| CA2190101A1 (en) | 1994-05-13 | 1995-11-23 | Donald Leonard Nicholas Cardy | Improvements in or relating to peptide delivery |
| NZ290089A (en) * | 1994-07-27 | 1999-05-28 | Queensland Inst Med Res | Recombinant polyepitope cytotoxic t lymphocyte (ctl) vaccines |
| US5698679A (en) * | 1994-09-19 | 1997-12-16 | National Jewish Center For Immunology And Respiratory Medicine | Product and process for targeting an immune response |
| AUPO784197A0 (en) * | 1997-07-10 | 1997-08-07 | Csl Limited | Treatment of nasopharyngeal carcinoma |
| CN1294517A (zh) * | 1997-11-14 | 2001-05-09 | 欧洲细胞技术有限公司 | 具有合成可变区和修饰特异性的免疫球蛋白分子 |
| WO2000064488A2 (en) | 1999-04-27 | 2000-11-02 | Eurogen Holding, S.A. | Somatic transgene immunization and related methods |
| US7067110B1 (en) * | 1999-07-21 | 2006-06-27 | Emd Lexigen Research Center Corp. | Fc fusion proteins for enhancing the immunogenicity of protein and peptide antigens |
| GB0102145D0 (en) * | 2001-01-26 | 2001-03-14 | Scancell Ltd | Substances |
| GB0111628D0 (en) | 2001-05-11 | 2001-07-04 | Scancell Ltd | Binding member |
| US7419957B2 (en) * | 2001-08-22 | 2008-09-02 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Peptides of melanoma antigen and their use in diagnostic, prophylactic and therapeutic methods |
| WO2004030616A2 (en) * | 2002-09-17 | 2004-04-15 | Antigen Express, Inc. | Ii-KEY/ANTIGENIC EPITOPE HYBRID PEPTIDE VACCINES |
| GB0706070D0 (en) | 2007-03-28 | 2007-05-09 | Scancell Ltd | Nucleic acids |
-
2007
- 2007-03-28 GB GBGB0706070.0A patent/GB0706070D0/en not_active Ceased
-
2008
- 2008-03-28 ES ES08735583.0T patent/ES2638188T3/es active Active
- 2008-03-28 AT AT10152624T patent/ATE529128T1/de active
- 2008-03-28 KR KR1020177009184A patent/KR20170040387A/ko not_active Ceased
- 2008-03-28 EP EP10152624A patent/EP2193803B1/en active Active
- 2008-03-28 KR KR1020157000952A patent/KR20150013357A/ko not_active Ceased
- 2008-03-28 JP JP2010500296A patent/JP5415399B2/ja active Active
- 2008-03-28 BR BRPI0808599A patent/BRPI0808599A2/pt not_active Application Discontinuation
- 2008-03-28 ES ES10152624T patent/ES2375463T3/es active Active
- 2008-03-28 PT PT87355830T patent/PT2134357T/pt unknown
- 2008-03-28 KR KR1020167020295A patent/KR101729458B1/ko active Active
- 2008-03-28 CN CN200880017669.4A patent/CN101678092B/zh active Active
- 2008-03-28 AU AU2008231723A patent/AU2008231723B2/en active Active
- 2008-03-28 WO PCT/EP2008/053761 patent/WO2008116937A2/en not_active Ceased
- 2008-03-28 DK DK10152624.2T patent/DK2193803T3/da active
- 2008-03-28 DK DK08735583.0T patent/DK2134357T3/en active
- 2008-03-28 PL PL08735583T patent/PL2134357T3/pl unknown
- 2008-03-28 PT PT10152624T patent/PT2193803E/pt unknown
- 2008-03-28 KR KR1020097021806A patent/KR20100015699A/ko not_active Ceased
- 2008-03-28 CN CN201310487984.6A patent/CN103667304B/zh active Active
- 2008-03-28 EP EP08735583.0A patent/EP2134357B1/en active Active
- 2008-03-28 CA CA2681531A patent/CA2681531C/en active Active
-
2009
- 2009-09-24 US US12/566,465 patent/US8742088B2/en active Active
- 2009-10-16 ZA ZA2009/07242A patent/ZA200907242B/en unknown
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