JP2010522185A5 - - Google Patents
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- Publication number
- JP2010522185A5 JP2010522185A5 JP2009554635A JP2009554635A JP2010522185A5 JP 2010522185 A5 JP2010522185 A5 JP 2010522185A5 JP 2009554635 A JP2009554635 A JP 2009554635A JP 2009554635 A JP2009554635 A JP 2009554635A JP 2010522185 A5 JP2010522185 A5 JP 2010522185A5
- Authority
- JP
- Japan
- Prior art keywords
- myricetin
- quercetin
- chlorogenic acid
- composition
- effective amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- IKMDFBPHZNJCSN-UHFFFAOYSA-N myricetin Chemical compound C=1C(O)=CC(O)=C(C(C=2O)=O)C=1OC=2C1=CC(O)=C(O)C(O)=C1 IKMDFBPHZNJCSN-UHFFFAOYSA-N 0.000 claims 10
- CWVRJTMFETXNAD-FWCWNIRPSA-N 3-O-Caffeoylquinic acid Natural products O[C@H]1[C@@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-FWCWNIRPSA-N 0.000 claims 5
- CWVRJTMFETXNAD-JUHZACGLSA-N Chlorogenic acid Chemical compound O[C@@H]1[C@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-JUHZACGLSA-N 0.000 claims 5
- 229940074393 Chlorogenic acid Drugs 0.000 claims 5
- REFJWTPEDVJJIY-UHFFFAOYSA-N Quercetin Chemical compound C=1C(O)=CC(O)=C(C(C=2O)=O)C=1OC=2C1=CC=C(O)C(O)=C1 REFJWTPEDVJJIY-UHFFFAOYSA-N 0.000 claims 5
- 229960001285 Quercetin Drugs 0.000 claims 5
- 235000001368 chlorogenic acid Nutrition 0.000 claims 5
- 235000007743 myricetin Nutrition 0.000 claims 5
- 229940116852 myricetin Drugs 0.000 claims 5
- 229930002344 quercetin Natural products 0.000 claims 5
- 235000005875 quercetin Nutrition 0.000 claims 5
- 235000013305 food Nutrition 0.000 claims 2
- 239000002778 food additive Substances 0.000 claims 2
- 235000013373 food additive Nutrition 0.000 claims 2
- 206010012601 Diabetes mellitus Diseases 0.000 claims 1
- 208000008589 Obesity Diseases 0.000 claims 1
- 150000001720 carbohydrates Chemical class 0.000 claims 1
- 230000002641 glycemic Effects 0.000 claims 1
- 235000020824 obesity Nutrition 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
Claims (5)
- クロロゲン酸：クエルセチン：ミリセチンの重量比が１:２〜４:２〜４の範囲にある、治療的に有効量のクエルセチン、ミリセチンおよびクロロゲン酸を含む、糖尿病または肥満症の治療または予防用組成物。
- クエルセチン約50 mg〜約500 mg、ミリセチン約50ｍｇ〜約500 mgおよびクロロゲン酸約25ｍｇ〜約150 mg を含む、請求項１に記載の組成物。
- クロロゲン酸：クエルセチン：ミリセチンの重量比が１:２〜４:２〜４の範囲にある、有効量のクエルセチン、ミリセチンおよびクロロゲン酸を含む、炭水化物含有食品のグリセミック指数低下用組成物。
- 請求項３に記載の組成物を含む食品添加物。
- 請求項４に記載の食品添加物を含む食品。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89548607P | 2007-03-19 | 2007-03-19 | |
| PCT/US2008/056474 WO2008115723A1 (en) | 2007-03-19 | 2008-03-11 | Composition for treating diabetes and metabolic disorders with quercetin, myrcetin and chlorogenic acid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010522185A JP2010522185A (ja) | 2010-07-01 |
| JP2010522185A5 true JP2010522185A5 (ja) | 2011-02-03 |
Family
ID=39590291
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009554635A Pending JP2010522185A (ja) | 2007-03-19 | 2008-03-11 | 糖尿病および代謝障害を治療するためのクエルセチン、ミリセチンおよびクロロゲン酸の組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7943164B2 (ja) |
| EP (1) | EP2129371B1 (ja) |
| JP (1) | JP2010522185A (ja) |
| CN (1) | CN101674821B (ja) |
| BR (1) | BRPI0809047B8 (ja) |
| CA (1) | CA2685031A1 (ja) |
| MX (1) | MX2009009996A (ja) |
| WO (1) | WO2008115723A1 (ja) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2129371B1 (en) * | 2007-03-19 | 2021-05-05 | ATM Metabolics LLLP | Composition for treating diabetes and metabolic disorders with quercetin, myrcetin and chlorogenic acid |
| JP5524466B2 (ja) * | 2008-10-31 | 2014-06-18 | ユニテックフーズ株式会社 | 中性風味デザートベース |
| US20100178413A1 (en) * | 2008-12-17 | 2010-07-15 | Mark Gorris | Food-based Supplement Delivery System |
| US9918489B2 (en) * | 2008-12-17 | 2018-03-20 | Mark Gorris | Food-based supplement delivery system |
| JP2011001311A (ja) * | 2009-06-19 | 2011-01-06 | Pola Chemical Industries Inc | 熱産生タンパク質発現促進剤 |
| WO2011019654A1 (en) * | 2009-08-10 | 2011-02-17 | Stokely-Van Camp, Inc. | Method for suspending a flavonoid in a beverage |
| CN102711522B (zh) | 2010-01-29 | 2015-09-09 | 雅培制药有限公司 | 包含hmb的无菌包装的营养液 |
| SG182812A1 (en) | 2010-01-29 | 2012-09-27 | Abbott Lab | Nutritional emulsions comprising calcium hmb |
| US9693577B2 (en) | 2010-01-29 | 2017-07-04 | Abbott Laboratories | Method of preparing a nutritional powder comprising spray dried HMB |
| TWI526161B (zh) | 2010-06-10 | 2016-03-21 | 亞培公司 | 包含鈣ｈｍｂ及可溶性蛋白質之實質上透明營養液 |
| US8372447B2 (en) * | 2010-08-03 | 2013-02-12 | Northern Innovations And Formulations Corp. | Compositions and methods for promoting weight loss and increasing energy |
| WO2012097064A1 (en) * | 2011-01-13 | 2012-07-19 | Abbott Laboratories | Nutritional compositions and methods for controlling blood glucose |
| WO2012114204A2 (en) * | 2011-02-15 | 2012-08-30 | Ecole Polytechnique Federale De Lausanne (Epfl) Epfl-Tto | Methods of treating mitochondrial dysfunction |
| AU2012266581B2 (en) | 2011-06-06 | 2014-10-30 | Unilever Ip Holdings B.V. | An edible composition |
| CN103620414A (zh) | 2011-06-28 | 2014-03-05 | 皇家飞利浦有限公司 | 用于体液检查的部件 |
| CN102772424B (zh) * | 2012-06-13 | 2014-01-08 | 浙江大学 | 新橙皮苷在制备防治糖尿病药物中的应用 |
| KR101396059B1 (ko) * | 2012-06-25 | 2014-05-16 | 중앙대학교 산학협력단 | 소귀나무잎으로부터 분리된 신규 황산염 페놀성 화합물 및 이의 항산화 및 항염 용도 |
| EP2867675B1 (en) | 2012-06-29 | 2017-11-29 | Koninklijke Philips N.V. | Processing of fluids containing interfering particles |
| RU2015102829A (ru) | 2012-06-29 | 2016-08-20 | Конинклейке Филипс Н.В. | Обработка связанных и несвязанных магнитных частиц |
| JP6309950B2 (ja) | 2012-07-18 | 2018-04-11 | コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． | 標的成分を持つ試料流体の処理 |
| WO2014083474A1 (en) | 2012-11-30 | 2014-06-05 | Koninklijke Philips N.V. | Capture particle for selectively binding a target molecule |
| US11071767B2 (en) | 2014-04-13 | 2021-07-27 | Marmar Investment Sp. Z O.O. | Dietary compositions for reducing blood glucose levels and for weight management |
| EP3161485B1 (en) | 2014-06-25 | 2018-10-31 | Koninklijke Philips N.V. | Biosensor for the detection of target components in a sample |
| WO2016088029A1 (en) * | 2014-12-01 | 2016-06-09 | Cape Kingdom Nutraceuticals (Pty) Ltd | Therapeutic compositions |
| JP6594995B2 (ja) | 2015-03-26 | 2019-10-23 | コーニンクレッカ フィリップス エヌ ヴェ | バイオセンサカートリッジの製造 |
| CN105816473B (zh) * | 2015-07-06 | 2018-04-10 | 武汉华纳联合药业有限公司 | 一种黄酮苷类组合物及其制剂和制法 |
| JP2017105745A (ja) * | 2015-12-02 | 2017-06-15 | 共栄化学工業株式会社 | 皮膚外用剤 |
| US20180133243A1 (en) * | 2016-11-16 | 2018-05-17 | Holista Colltech Ltd | Method and composition for crude formulations of fortified sugar for glycemic control |
| TWI671081B (zh) * | 2017-04-03 | 2019-09-11 | 大江生醫股份有限公司 | 用以提升轉谷氨醯胺酶１基因、角蛋白基因、水通道蛋白３基因、聚角蛋白微絲基因、葡萄糖腦苷酯酶基因、及玻尿酸合成酶基因表現之含有植物萃取物之組成物的用途 |
| WO2020247961A1 (en) * | 2019-06-07 | 2020-12-10 | Advanced Delivery Labs Llc | Compositions and methods for improving wellness |
| CN111387504A (zh) * | 2020-04-15 | 2020-07-10 | 武汉森澜生物科技有限公司 | 一种含绿原酸和柚皮苷的活性提取物、提取方法及其用途 |
| WO2023192259A1 (en) * | 2022-03-28 | 2023-10-05 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Synergy for increasing insulin sensitivity |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3134233B2 (ja) | 1991-07-26 | 2001-02-13 | 株式会社林原生物化学研究所 | α−グリコシル ケルセチンとその製造方法並びに用途 |
| DE69826253D1 (de) * | 1997-03-20 | 2004-10-21 | Coventry Group Ltd | Nährungsergänzungsmittel für kardiovasküläre gesundheit |
| US7229651B2 (en) | 1997-08-06 | 2007-06-12 | Melaleuca, Inc. | Dietary supplements containing natural ingredients |
| KR20000019716A (ko) | 1998-09-15 | 2000-04-15 | 박호군 | 바이오플라보노이드 화합물을 포함하는 혈당 강하용 조성물 |
| US20020068704A1 (en) | 1999-04-05 | 2002-06-06 | Ziegler Randy H. | Compositions and methods for treatment of diabetes |
| CA2405348A1 (en) | 2000-04-13 | 2001-11-01 | Ocean Spray Cranberries, Inc. | Novel compositions derived from cranberry and grapefruit and therapeutic uses therefor |
| US20030108627A1 (en) | 2001-09-25 | 2003-06-12 | Jonathan Selzer | Cranberry based dietary supplement and dental hygiene product |
| US20030133945A1 (en) * | 2002-01-11 | 2003-07-17 | Farley Michael Donald | Natural food supplement |
| KR20050073611A (ko) * | 2002-11-06 | 2005-07-14 | 카오카부시키가이샤 | 혈액 유동성 개선제 |
| US7270837B2 (en) | 2003-11-10 | 2007-09-18 | Rutgers, The State University Of New Jersey | Anti-inflammatory cranberry flavonol extract preparations |
| US8017634B2 (en) | 2003-12-29 | 2011-09-13 | President And Fellows Of Harvard College | Compositions for treating obesity and insulin resistance disorders |
| WO2006024545A1 (en) | 2004-09-03 | 2006-03-09 | Stichting Voor De Technische Wetenschappen | Fused bicyclic natural compounds and their use as inhibitors of parp and parp-mediated inflammatory processes |
| WO2006074278A2 (en) | 2005-01-05 | 2006-07-13 | Mitsunori Ono | Compositions for treating diabetes or obesity |
| US20070092454A1 (en) | 2005-10-24 | 2007-04-26 | Colgate-Palmolive Company | Oral composition containing morin |
| EP2129371B1 (en) | 2007-03-19 | 2021-05-05 | ATM Metabolics LLLP | Composition for treating diabetes and metabolic disorders with quercetin, myrcetin and chlorogenic acid |
-
2008
- 2008-03-11 EP EP08731870.5A patent/EP2129371B1/en active Active
- 2008-03-11 CN CN200880014120XA patent/CN101674821B/zh active Active
- 2008-03-11 CA CA002685031A patent/CA2685031A1/en not_active Abandoned
- 2008-03-11 WO PCT/US2008/056474 patent/WO2008115723A1/en active Application Filing
- 2008-03-11 US US12/045,852 patent/US7943164B2/en active Active
- 2008-03-11 BR BRPI0809047A patent/BRPI0809047B8/pt not_active IP Right Cessation
- 2008-03-11 JP JP2009554635A patent/JP2010522185A/ja active Pending
- 2008-03-11 MX MX2009009996A patent/MX2009009996A/es active IP Right Grant
-
2011
- 2011-01-27 US US13/014,798 patent/US8198319B2/en active Active
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