JP2010520280A5 - - Google Patents

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Publication number
JP2010520280A5
JP2010520280A5 JP2009552676A JP2009552676A JP2010520280A5 JP 2010520280 A5 JP2010520280 A5 JP 2010520280A5 JP 2009552676 A JP2009552676 A JP 2009552676A JP 2009552676 A JP2009552676 A JP 2009552676A JP 2010520280 A5 JP2010520280 A5 JP 2010520280A5
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JP
Japan
Prior art keywords
seq
notch2
notch1
numb1
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2009552676A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010520280A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2008/001694 external-priority patent/WO2008108910A2/en
Publication of JP2010520280A publication Critical patent/JP2010520280A/ja
Publication of JP2010520280A5 publication Critical patent/JP2010520280A5/ja
Withdrawn legal-status Critical Current

Links

JP2009552676A 2007-03-05 2008-02-08 ＮｏｔｃｈまたはＮｕｍｂ特異的免疫療法との相乗効果を有する、癌細胞の再生のネガティブな遺伝的制御 Withdrawn JP2010520280A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US90499407P 2007-03-05 2007-03-05
US96104607P 2007-07-18 2007-07-18
US95994607P 2007-07-18 2007-07-18
US95997107P 2007-07-18 2007-07-18
PCT/US2008/001694 WO2008108910A2 (en) 2007-03-05 2008-02-08 Negative genetic regulation of cancer cell renewal in synergy with notch- or numb-specific immunotherapy

Publications (2)

Publication Number Publication Date
JP2010520280A JP2010520280A (ja) 2010-06-10
JP2010520280A5 true JP2010520280A5 (https=) 2012-04-12

Family

ID=39539638

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009552676A Withdrawn JP2010520280A (ja) 2007-03-05 2008-02-08 ＮｏｔｃｈまたはＮｕｍｂ特異的免疫療法との相乗効果を有する、癌細胞の再生のネガティブな遺伝的制御

Country Status (4)

Country Link
US (1) US20100062012A1 (https=)
EP (1) EP2134356A2 (https=)
JP (1) JP2010520280A (https=)
WO (1) WO2008108910A2 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6984522B2 (en) 2000-08-03 2006-01-10 Regents Of The University Of Michigan Isolation and use of solid tumor stem cells
US7919092B2 (en) 2006-06-13 2011-04-05 Oncomed Pharmaceuticals, Inc. Antibodies to notch receptors
EP2125887A4 (en) 2007-01-24 2010-11-10 Oncomed Pharm Inc COMPOSITIONS AND METHODS OF TREATMENT AND DIAGNOSIS OF CANCER
CN104402998A (zh) 2008-07-08 2015-03-11 昂考梅德药品有限公司 分离的抗体
US9132189B2 (en) 2008-07-08 2015-09-15 Oncomed Pharmaceuticals, Inc. Notch1 binding agents and methods of use thereof
JP6059985B2 (ja) 2009-06-18 2017-01-11 ファイザー・インク 抗ｎｏｔｃｈ−１抗体
CA2775880A1 (en) 2009-09-30 2011-04-07 Genentech, Inc. Anti-notch3 antagonist antibodies to treat gamma secretase inhibitor responsive and anti-notch1 antagonist antibody unresponsive t-cell leukemias
MX2012008085A (es) 2010-01-13 2012-09-12 Oncomed Pharm Inc Agentes de union notch1 y metodos de uso de los mismos.
SG191039A1 (en) 2010-12-15 2013-08-30 Wyeth Llc Anti-notch1 antibodies
KR101535219B1 (ko) * 2011-11-18 2015-07-09 한국생명공학연구원 Ｎｏｔｃｈ３에 대한 인간 단일클론항체
US9944700B2 (en) 2013-03-13 2018-04-17 Novartis Ag Notch2 binding molecules for treating respiratory diseases
CN109467598B (zh) * 2018-11-28 2021-11-09 生命谷（海南）生物科技股份有限公司 肿瘤相关基因notch1突变短肽及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8162898A (en) * 1997-06-18 1999-01-04 Trustees Of Columbia University In The City Of New York, The Angiogenic modulation by notch signal transduction
GB9927328D0 (en) * 1999-11-18 2000-01-12 Lorantis Ltd Immunotherapy
US20040126762A1 (en) * 2002-12-17 2004-07-01 Morris David W. Novel compositions and methods in cancer
EP1709150A4 (en) * 2003-11-26 2007-11-21 Health Research Inc USE OF NOTCH-INTERFERING MEDICAMENTS FOR THE TREATMENT OF PLASMA-CELL-RELATED DISEASES
GB0421838D0 (en) * 2004-09-30 2004-11-03 Congenia S R L Cancer markers

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