JP2010518035A5 - - Google Patents

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Publication number
JP2010518035A5
JP2010518035A5 JP2009548607A JP2009548607A JP2010518035A5 JP 2010518035 A5 JP2010518035 A5 JP 2010518035A5 JP 2009548607 A JP2009548607 A JP 2009548607A JP 2009548607 A JP2009548607 A JP 2009548607A JP 2010518035 A5 JP2010518035 A5 JP 2010518035A5
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JP
Japan
Prior art keywords
microreactor
fluid
schematic diagram
reaction zone
zone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2009548607A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010518035A (ja
JP5394258B2 (ja
Filing date
Publication date
Priority claimed from EP07002522A external-priority patent/EP1956023A1/en
Application filed filed Critical
Publication of JP2010518035A publication Critical patent/JP2010518035A/ja
Publication of JP2010518035A5 publication Critical patent/JP2010518035A5/ja
Application granted granted Critical
Publication of JP5394258B2 publication Critical patent/JP5394258B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2009548607A 2007-02-06 2008-02-01 リチウム交換反応のための方法 Active JP5394258B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07002522.6 2007-02-06
EP07002522A EP1956023A1 (en) 2007-02-06 2007-02-06 Method for lithium exchange reactions
PCT/EP2008/000808 WO2008095646A1 (en) 2007-02-06 2008-02-01 Method for lithium exchange reactions

Publications (3)

Publication Number Publication Date
JP2010518035A JP2010518035A (ja) 2010-05-27
JP2010518035A5 true JP2010518035A5 (enExample) 2011-03-17
JP5394258B2 JP5394258B2 (ja) 2014-01-22

Family

ID=38179681

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009548607A Active JP5394258B2 (ja) 2007-02-06 2008-02-01 リチウム交換反応のための方法

Country Status (17)

Country Link
US (1) US8198487B2 (enExample)
EP (2) EP1956023A1 (enExample)
JP (1) JP5394258B2 (enExample)
CN (1) CN101605800B (enExample)
AT (1) ATE478877T1 (enExample)
BR (1) BRPI0807155A2 (enExample)
CA (1) CA2674560A1 (enExample)
DE (1) DE602008002321D1 (enExample)
EA (1) EA015237B1 (enExample)
ES (1) ES2351376T3 (enExample)
HR (1) HRP20100627T1 (enExample)
IL (1) IL199749A (enExample)
MX (1) MX2009008352A (enExample)
PL (1) PL2109616T3 (enExample)
PT (1) PT2109616E (enExample)
SI (1) SI2109616T1 (enExample)
WO (1) WO2008095646A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE035130T2 (en) 2007-09-10 2018-05-02 Janssen Pharmaceutica Nv A method for preparing compounds useful as SGLT inhibitors
US9056850B2 (en) 2008-10-17 2015-06-16 Janssen Pharmaceutica N.V. Process for the preparation of compounds useful as inhibitors of SGLT
US20110009347A1 (en) 2009-07-08 2011-01-13 Yin Liang Combination therapy for the treatment of diabetes
DK2451797T3 (da) 2009-07-10 2013-06-24 Janssen Pharmaceutica Nv Fremgangsmåde til krystallisation for 1-(b-D-GLUCOPYRANOSYL)-4-METHYL-3-[5-(4-fluorphenyl)-2- thienylmethyl]benzen
EP2488515B1 (en) * 2009-10-14 2017-01-04 Janssen Pharmaceutica NV Process for the preparation of compounds useful as inhibitors of sglt2
TWI599360B (zh) 2010-05-11 2017-09-21 健生藥品公司 醫藥調配物
RS55056B1 (sr) 2011-04-13 2016-12-30 Janssen Pharmaceutica Nv Proces za pripremu jedinjenja koja su korisna kao inhibitori sglt2
TWI542596B (zh) 2011-05-09 2016-07-21 健生藥品公司 (2s,3r,4r,5s,6r)-2-(3-((5-(4-氟苯基)噻吩-2-基)甲基)-4-甲基苯基)-6-(羥甲基)四氫-2h-哌喃-3,4,5-三醇之l-脯胺酸及檸檬酸共晶體
US20170071970A1 (en) 2015-09-15 2017-03-16 Janssen Pharmaceutica Nv Co-therapy comprising canagliflozin and phentermine for the treatment of obesity and obesity related disorders
JP7754624B2 (ja) * 2017-11-14 2025-10-15 アルベマール・ジャーマニー・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 連続フロー条件下での有機リチウムプロセス
DE102019008481A1 (de) 2018-12-21 2020-06-25 Merck Patent Gmbh Kontinuierliches Verfahren zur Funktionalisierung von fluorierten Benzolverbindungen im Strömungsrohr
CN110510637B (zh) * 2019-08-22 2021-02-23 山东师范大学 一种锂循环合成氨的系统及工艺

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19858856A1 (de) * 1998-12-19 2000-06-21 Merck Patent Gmbh Verfahren zur Herstellung von Arylmetallverbindungen und deren Umsetzung mit Elektrophilen
DE10028754A1 (de) * 2000-06-09 2001-12-13 Clariant Gmbh Verfahren zur Herstellung von alkoholischen Lösungen von Alkalialkoholaten
DE10333174A1 (de) * 2003-07-22 2005-02-17 Cpc Cellular Process Chemistry Systems Gmbh Verfahren zur Durchführung einer In-Situ-Quench Reaktion
JP4639042B2 (ja) * 2003-09-29 2011-02-23 富士フイルムファインケミカルズ株式会社 ハロゲン−リチウム交換反応を用いる有機化合物の製造法
JP4794873B2 (ja) * 2005-03-03 2011-10-19 富士フイルムファインケミカルズ株式会社 ハロゲン−リチウム交換反応を用いる有機化合物の製造法
AT501927B1 (de) * 2005-05-23 2007-06-15 Dsm Fine Chem Austria Gmbh Verbessertes verfahren zur durchführung von ritterreaktionen, elektrophilen additionen an alkenen oder friedel-crafts-alkylierungen
JPWO2008035633A1 (ja) * 2006-09-19 2010-01-28 萬有製薬株式会社 反応装置及び反応方法

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