JP2010512781A5 - - Google Patents
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- Publication number
- JP2010512781A5 JP2010512781A5 JP2009542395A JP2009542395A JP2010512781A5 JP 2010512781 A5 JP2010512781 A5 JP 2010512781A5 JP 2009542395 A JP2009542395 A JP 2009542395A JP 2009542395 A JP2009542395 A JP 2009542395A JP 2010512781 A5 JP2010512781 A5 JP 2010512781A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- sflt
- sample
- pregnancy
- fetal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000012472 biological sample Substances 0.000 claims 5
- 230000035935 pregnancy Effects 0.000 claims 5
- 239000000523 sample Substances 0.000 claims 5
- 230000001605 fetal effect Effects 0.000 claims 4
- 230000008774 maternal effect Effects 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 3
- 208000001362 Fetal Growth Retardation Diseases 0.000 claims 2
- 206010016845 Foetal alcohol syndrome Diseases 0.000 claims 2
- 206010070531 Foetal growth restriction Diseases 0.000 claims 2
- 208000026934 fetal alcohol spectrum disease Diseases 0.000 claims 2
- 201000007794 fetal alcohol syndrome Diseases 0.000 claims 2
- 208000030941 fetal growth restriction Diseases 0.000 claims 2
- 201000011461 pre-eclampsia Diseases 0.000 claims 2
- 206010070538 Gestational hypertension Diseases 0.000 claims 1
- 210000004381 amniotic fluid Anatomy 0.000 claims 1
- 238000001574 biopsy Methods 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 210000004252 chorionic villi Anatomy 0.000 claims 1
- 208000004104 gestational diabetes Diseases 0.000 claims 1
- 230000003169 placental effect Effects 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87582206P | 2006-12-20 | 2006-12-20 | |
| PCT/IL2007/001589 WO2008075363A1 (en) | 2006-12-20 | 2007-12-20 | Variants of vegfr and their use in the diagnosis and treatment of pregnancy associated medical conditions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010512781A JP2010512781A (ja) | 2010-04-30 |
| JP2010512781A5 true JP2010512781A5 (enExample) | 2010-12-24 |
Family
ID=39271517
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009542395A Pending JP2010512781A (ja) | 2006-12-20 | 2007-12-20 | Vegfrの変化体ならびに妊娠関連の医学的状態の診断および処置におけるその使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US20100136012A1 (enExample) |
| EP (1) | EP2099913B1 (enExample) |
| JP (1) | JP2010512781A (enExample) |
| AT (1) | ATE547523T1 (enExample) |
| CA (1) | CA2673222A1 (enExample) |
| WO (1) | WO2008075363A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2099913B1 (en) | 2006-12-20 | 2012-02-29 | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. | Variants of vegfr and their use in the diagnosis and treatment of pregnancy associated medical conditions |
| JPWO2010106997A1 (ja) * | 2009-03-19 | 2012-09-20 | 株式会社カネカ | 核酸の検出方法及びキット、デバイス |
| US20130164270A1 (en) | 2009-07-29 | 2013-06-27 | Yissum Research Developement Company of the Hebrew University of Jerusalem Ltd. | Polynucleotides and constructs encoding sflt1-14 and method for efficient propagation and expression thereof |
| US20160024181A1 (en) | 2013-03-13 | 2016-01-28 | Moderna Therapeutics, Inc. | Long-lived polynucleotide molecules |
| RU2670747C1 (ru) * | 2017-10-19 | 2018-10-25 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Российский национальный исследовательский медицинский университет им. Н.И. Пирогова" Министерства здравоохранения Российской Федерации (ФГБОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России) | Способ определения показаний для срочного родоразрешения при преэклампсии |
| FR3081707A1 (fr) * | 2018-05-30 | 2019-12-06 | Universite De Rouen Normandie | Traitement des troubles neurologiques causes par l'alcoolisation foetale |
| WO2020171777A1 (en) * | 2019-02-18 | 2020-08-27 | Agency For Science, Technology And Research | A membrane-bound fit-1 decoy and uses thereof |
| EP4070113A4 (en) | 2019-12-04 | 2023-12-20 | Biora Therapeutics, Inc. | ASSESSMENT OF PREECAMPSIA USING FREE AND DISSOCIATE PLACENTAL GROWTH FACTOR ASSAYS |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6710174B2 (en) * | 2001-09-13 | 2004-03-23 | Isis Pharmaceuticals, Inc. | Antisense inhibition of vascular endothelial growth factor receptor-1 expression |
| AU2001238347A1 (en) * | 2000-02-28 | 2001-09-12 | Hyseq, Inc. | Novel nucleic acids and polypeptides |
| US20040216828A1 (en) * | 2001-08-17 | 2004-11-04 | Ortega Albert E. | Nonwoven fabrics with two or more filament cross sections |
| KR101215701B1 (ko) * | 2002-07-19 | 2012-12-26 | 베스 이스라엘 데코니스 메디칼 센터 | 자간전증 또는 자간의 진단 및 치료 방법 |
| US7939634B2 (en) * | 2004-01-27 | 2011-05-10 | Compugen Ltd. | Polynucleotides encoding polypeptides and methods using same |
| US20080305493A1 (en) | 2004-03-08 | 2008-12-11 | Avalon Pharmaceuticals | Determining Cancer-Linked Genes and Therapeutic Targets Using Molecular Cytogenetic Methods |
| JP5009811B2 (ja) * | 2004-12-21 | 2012-08-22 | イェール ユニバーシティ | 子癇前症の検出 |
| IL172297A (en) * | 2005-10-03 | 2016-03-31 | Compugen Ltd | Soluble vegfr-1 variants for the diagnosis of preeclampsia |
| EP2099913B1 (en) | 2006-12-20 | 2012-02-29 | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. | Variants of vegfr and their use in the diagnosis and treatment of pregnancy associated medical conditions |
-
2007
- 2007-12-20 EP EP07849615A patent/EP2099913B1/en not_active Not-in-force
- 2007-12-20 WO PCT/IL2007/001589 patent/WO2008075363A1/en not_active Ceased
- 2007-12-20 AT AT07849615T patent/ATE547523T1/de active
- 2007-12-20 JP JP2009542395A patent/JP2010512781A/ja active Pending
- 2007-12-20 CA CA002673222A patent/CA2673222A1/en not_active Abandoned
- 2007-12-20 US US12/448,404 patent/US20100136012A1/en not_active Abandoned
-
2012
- 2012-11-27 US US13/685,892 patent/US20130084583A1/en not_active Abandoned
-
2014
- 2014-06-15 US US14/304,948 patent/US9797911B2/en not_active Expired - Fee Related
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