JP2010511381A5 - - Google Patents
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- JP2010511381A5 JP2010511381A5 JP2009539185A JP2009539185A JP2010511381A5 JP 2010511381 A5 JP2010511381 A5 JP 2010511381A5 JP 2009539185 A JP2009539185 A JP 2009539185A JP 2009539185 A JP2009539185 A JP 2009539185A JP 2010511381 A5 JP2010511381 A5 JP 2010511381A5
- Authority
- JP
- Japan
- Prior art keywords
- neural
- stem cells
- cells
- cultured
- mesenchymal stem
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 210000001178 Neural Stem Cells Anatomy 0.000 claims 4
- 230000001537 neural Effects 0.000 claims 4
- 210000002901 Mesenchymal Stem Cells Anatomy 0.000 claims 3
- 210000004700 Fetal Blood Anatomy 0.000 claims 2
- 210000000130 stem cell Anatomy 0.000 claims 2
- 210000004027 cells Anatomy 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- OZAIFHULBGXAKX-UHFFFAOYSA-N precursor Substances N#CC(C)(C)N=NC(C)(C)C#N OZAIFHULBGXAKX-UHFFFAOYSA-N 0.000 claims 1
- 230000035755 proliferation Effects 0.000 claims 1
Claims (2)
- 臍帯血由来の間葉系幹細胞を神経前駆細胞又は神経幹細胞と共同培養することを含む、神経前駆細胞又は神経幹細胞の増殖の誘導方法であって、
前記神経前駆細胞又は前記神経幹細胞の数は、共同培養した前記間葉系幹細胞の濃度に従って増加することを特徴とする方法。 - 請求項1において、
前記臍帯血由来間葉系幹細胞と神経前駆細胞又は神経幹細胞の比率が1:0.1乃至1:10であることを特徴とする方法。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US86787506P | 2006-11-30 | 2006-11-30 | |
KR1020060120479A KR100959995B1 (ko) | 2006-12-01 | 2006-12-01 | 인간 제대혈 유래 간엽 줄기세포를 유효성분으로 포함하는,신경전구세포 또는 신경줄기세포의 신경세포로의 분화 및증식 유도용 조성물 |
PCT/KR2007/006084 WO2008066330A1 (en) | 2006-11-30 | 2007-11-29 | Use of a composition contaning human umbilical cord blood-derived mesenchymal stem cell for inducing differentiation and proliferation of neural precursor cells or neural stem cells to neural cells |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2013160426A Division JP5871865B2 (ja) | 2006-11-30 | 2013-08-01 | 神経前駆細胞又は神経幹細胞の神経細胞への分化及び増殖の誘導方法、分化及び増殖誘導用組成物、及び薬学的製剤 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2010511381A JP2010511381A (ja) | 2010-04-15 |
JP2010511381A5 true JP2010511381A5 (ja) | 2015-02-26 |
Family
ID=39468070
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2009539185A Pending JP2010511381A (ja) | 2006-11-30 | 2007-11-29 | 神経前駆細胞又は神経幹細胞の神経細胞への分化及び増殖の誘導方法、分化及び増殖誘導用組成物、及び薬学的製剤 |
JP2013160426A Active JP5871865B2 (ja) | 2006-11-30 | 2013-08-01 | 神経前駆細胞又は神経幹細胞の神経細胞への分化及び増殖の誘導方法、分化及び増殖誘導用組成物、及び薬学的製剤 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2013160426A Active JP5871865B2 (ja) | 2006-11-30 | 2013-08-01 | 神経前駆細胞又は神経幹細胞の神経細胞への分化及び増殖の誘導方法、分化及び増殖誘導用組成物、及び薬学的製剤 |
Country Status (9)
Country | Link |
---|---|
US (2) | US9387226B2 (ja) |
EP (1) | EP2099901B1 (ja) |
JP (2) | JP2010511381A (ja) |
CN (1) | CN101541954B (ja) |
AU (1) | AU2007326171B2 (ja) |
CA (1) | CA2669304C (ja) |
HK (1) | HK1134688A1 (ja) |
MX (1) | MX2009005496A (ja) |
WO (1) | WO2008066330A1 (ja) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ591292A (en) | 2008-08-20 | 2012-10-26 | Anthrogenesis Corp | Improved cell composition and methods of making the same |
CN101831401A (zh) * | 2010-04-23 | 2010-09-15 | 天津昂赛细胞基因工程有限公司 | 体外诱导间充质干细胞分化为神经干细胞的方法 |
US11286463B2 (en) | 2012-03-08 | 2022-03-29 | Advanced ReGen Medical Technologies, LLC | Reprogramming of aged adult stem cells |
EP3689357A1 (en) * | 2013-04-09 | 2020-08-05 | Advanced Regen Medical Technologies, LLC | Compositions for cellular restoration and methods of making and using same |
JP6353073B2 (ja) | 2013-12-20 | 2018-07-04 | アドヴァンスド リジェン メディカル テクノロジーズ,エルエルシー | 細胞回復のための組成物並びにその作製及び使用方法 |
US10772911B2 (en) | 2013-12-20 | 2020-09-15 | Advanced ReGen Medical Technologies, LLC | Cell free compositions for cellular restoration and methods of making and using same |
EP3214171A4 (en) * | 2014-10-29 | 2018-07-11 | Sungkwang Medical Foundation | Placenta-derived cells excreting c3 or c1r complement and composition containing same |
US11827904B2 (en) | 2015-04-29 | 2023-11-28 | Fred Hutchinson Cancer Center | Modified stem cells and uses thereof |
CN106701668B (zh) * | 2015-07-22 | 2020-12-29 | 中国医药大学 | 间质干细胞、其纯株化扩张的方法及其应用 |
US11110129B2 (en) | 2015-07-22 | 2021-09-07 | China Medical University | Method for treating multiple sclerosis |
TWI589698B (zh) | 2015-07-22 | 2017-07-01 | 中國醫藥大學 | 間質幹細胞、其純株化擴張之方法、其分離方法及其應用 |
ITUB20159750A1 (it) * | 2015-12-30 | 2017-06-30 | Alfredo Gorio | Metodo per la promozione ed il miglioramento delle proprieta? del tessuto adiposo, tessuto e cellule ottenute tramite detto metodo |
JP7101367B2 (ja) | 2016-04-28 | 2022-07-15 | 北海道公立大学法人 札幌医科大学 | シナプス形成剤 |
JP6999575B2 (ja) | 2016-04-29 | 2022-01-18 | アドヴァンスド リジェン メディカル テクノロジーズ,エルエルシー | マイクロrna組成物並びにその作製及び使用方法 |
WO2017205667A1 (en) * | 2016-05-25 | 2017-11-30 | Terumo Bct, Inc. | Cell expansion |
US10717981B2 (en) | 2018-01-18 | 2020-07-21 | Advanced ReGen Medical Technologies, LLC | Therapeutic compositions and methods of making and using the same |
WO2019237106A1 (en) * | 2018-06-08 | 2019-12-12 | University Of Virginia Patent Foundation | Compositions and methods for treating stroke |
JPWO2022004822A1 (ja) * | 2020-06-30 | 2022-01-06 |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7354588B1 (en) | 1987-05-04 | 2008-04-08 | Dana Farber Cancer Institute | Functional derivatives of ICAM-1 with altered ability to bind LFA-1 or HRV |
US5733542A (en) | 1990-11-16 | 1998-03-31 | Haynesworth; Stephen E. | Enhancing bone marrow engraftment using MSCS |
US5837576A (en) | 1997-10-31 | 1998-11-17 | Vanguard International Semiconductor Corporation | Method for forming a capacitor using a silicon oxynitride etching stop layer |
US6900299B1 (en) | 1999-03-11 | 2005-05-31 | University Of South Florida | Interrupting the interaction of intercellular adhesion molecule-1 and respiratory syncytial virus for prevention and treatment of infection |
ES2338890T3 (es) | 1999-03-12 | 2010-05-13 | The Board Of Trustees Of The Leland Stanford Junior University | Vacunacion por dna para el tratamiento de enfermedades autoinmunes. |
US6372494B1 (en) | 1999-05-14 | 2002-04-16 | Advanced Tissue Sciences, Inc. | Methods of making conditioned cell culture medium compositions |
US20040208858A1 (en) | 2000-04-12 | 2004-10-21 | Gihan Tennekoon | Therapeutic uses for mesenchymal stromal cells |
EP1302534A4 (en) | 2000-06-26 | 2004-06-16 | Renomedix Inst Inc | CELL FRACTIONS CONTAINING CELLS CAPABLE OF DIFFERENCING INTO NEURAL CELLS |
US20040037775A1 (en) | 2000-08-01 | 2004-02-26 | Siahaan Teruna J. | Leukocyte internalized peptide-drug conjugates |
US7560280B2 (en) * | 2000-11-03 | 2009-07-14 | Kourion Therapeutics Gmbh | Human cord blood derived unrestricted somatic stem cells (USSC) |
KR100449141B1 (ko) * | 2001-04-19 | 2004-09-21 | (주)라이프코드 | 간엽 간세포를 신경세포로 분화시키는 방법 |
WO2003070922A1 (en) * | 2002-02-19 | 2003-08-28 | Medipost Co., Ltd. | Isolation and culture-expansion methods of mesenchymal stem/progenitor cells from umbilical cord blood, and differentiation method of umbilical cord blood-derived mesenchymal stem/progenitor cells into various mesenchymal tissues |
US20090192105A1 (en) | 2002-02-20 | 2009-07-30 | Sirna Therapeutics, Inc. | RNA INTERFERENCE MEDIATED INHIBITION OF INTERCELLULAR ADHESION MOLECULE (ICAM) GENE EXPRESSION USING SHORT INTERFERING NUCELIC ACID (siNA) |
AU2003252559A1 (en) | 2002-08-17 | 2004-03-03 | Hae-Young Suh | A method for transdifferentiating mesenchymal stem cells into neuronal cells |
US20040203142A1 (en) * | 2003-04-14 | 2004-10-14 | Reliance Life Sciences Pvt. Ltd. | Growth of neural precursor cells using umbilical cord blood serum and a process for the preparation thereof for therapeutic purposes |
JP5099288B2 (ja) | 2003-09-09 | 2012-12-19 | 学校法人慶應義塾 | 神経幹細胞の生存及び/又は増殖及び神経突起伸張を促進する方法並びに促進剤、神経幹細胞を含む医薬組成物、検定方法、スクリーニング方法 |
US20060094064A1 (en) | 2003-11-19 | 2006-05-04 | Sandip Ray | Methods and compositions for diagnosis, stratification, and monitoring of alzheimer's disease and other neurological disorders in body fluids |
US7943660B2 (en) | 2005-04-15 | 2011-05-17 | Dominion Pharmakine S.L. | Inhibitors of the LFA-1/ICAM-1 interaction and uses thereof |
EP1767617A1 (en) | 2005-09-26 | 2007-03-28 | Letizia Mazzini | Mesenchymal stem cells isolation and expansion method and uses thereof |
US20070253931A1 (en) | 2006-01-12 | 2007-11-01 | Osiris Therapeutics, Inc. | Use of mesenchymal stem cells for treating genetic diseases and disorders |
KR100792184B1 (ko) | 2006-05-12 | 2008-01-07 | 재단법인서울대학교산학협력재단 | 개의 제대혈, 태반 및 개 태아의 심장 유래 다분화능 성체줄기세포, 그 제조방법 및 이를 함유하는 세포 치료제 |
KR20080049562A (ko) | 2006-11-30 | 2008-06-04 | 가톨릭대학교 산학협력단 | 제대혈 유래 간엽 줄기세포를 유효성분으로 포함하는 신경손상 질환 치료제 |
KR20100054711A (ko) | 2008-11-14 | 2010-05-25 | 메디포스트(주) | 간엽 줄기세포 또는 이의 배양액을 포함하는 신경질환의 예방 또는 치료용 조성물 |
-
2007
- 2007-11-29 MX MX2009005496A patent/MX2009005496A/es active IP Right Grant
- 2007-11-29 CA CA2669304A patent/CA2669304C/en active Active
- 2007-11-29 CN CN2007800440974A patent/CN101541954B/zh active Active
- 2007-11-29 US US12/516,913 patent/US9387226B2/en active Active
- 2007-11-29 AU AU2007326171A patent/AU2007326171B2/en active Active
- 2007-11-29 WO PCT/KR2007/006084 patent/WO2008066330A1/en active Application Filing
- 2007-11-29 JP JP2009539185A patent/JP2010511381A/ja active Pending
- 2007-11-29 EP EP07851154.0A patent/EP2099901B1/en active Active
-
2010
- 2010-03-17 HK HK10102815.7A patent/HK1134688A1/xx unknown
-
2013
- 2013-08-01 JP JP2013160426A patent/JP5871865B2/ja active Active
- 2013-08-19 US US13/970,074 patent/US9439931B2/en active Active
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