JP2010509937A5 - - Google Patents
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- Publication number
- JP2010509937A5 JP2010509937A5 JP2009538451A JP2009538451A JP2010509937A5 JP 2010509937 A5 JP2010509937 A5 JP 2010509937A5 JP 2009538451 A JP2009538451 A JP 2009538451A JP 2009538451 A JP2009538451 A JP 2009538451A JP 2010509937 A5 JP2010509937 A5 JP 2010509937A5
- Authority
- JP
- Japan
- Prior art keywords
- monoclonal antibody
- antigen
- variable region
- cell line
- binding fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000000427 antigen Substances 0.000 claims 3
- 102000036639 antigens Human genes 0.000 claims 3
- 108091007433 antigens Proteins 0.000 claims 3
- 239000012634 fragment Substances 0.000 claims 3
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 1
- 241000191967 Staphylococcus aureus Species 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 210000004748 cultured cell Anatomy 0.000 claims 1
- 210000004408 hybridoma Anatomy 0.000 claims 1
- 150000007523 nucleic acids Chemical group 0.000 claims 1
- 108091033319 polynucleotide Proteins 0.000 claims 1
- 102000040430 polynucleotide Human genes 0.000 claims 1
- 239000002157 polynucleotide Substances 0.000 claims 1
- 238000004321 preservation Methods 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
Claims (3)
- モノクローナル抗体、及びその抗原結合性フラグメントであって、前記モノクローナル抗体が、米国培養細胞系統保存機関に寄託され、受入番号ＰＴＡ−７９３８が付与されたハイブリドーマ細胞株３５８Ａ７６．１より産生されるモノクローナル抗体７６によって認識される黄色ブドウ球菌由来のプロテインＡの同一エピトープに結合する、モノクローナル抗体、及びその抗原結合性フラグメント。
- 請求項１に記載のモノクローナル抗体、又はその抗原結合性フラグメントを含む、組成物。
- 請求項１に記載のモノクローナル抗体の重鎖、軽鎖、重鎖可変領域、軽鎖可変領域、又は１つ以上の相補的決定領域をコードする核酸配列を含む、単離されたポリヌクレオチド。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/562,759 US7488807B2 (en) | 2006-11-22 | 2006-11-22 | Antibody with protein A selectivity |
| PCT/US2007/084736 WO2008140570A2 (en) | 2006-11-22 | 2007-11-15 | Antibody with protein a selectivity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010509937A JP2010509937A (ja) | 2010-04-02 |
| JP2010509937A5 true JP2010509937A5 (ja) | 2011-01-06 |
Family
ID=39417386
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009538451A Withdrawn JP2010509937A (ja) | 2006-11-22 | 2007-11-15 | プロテインａ選択性を有する抗体 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US7488807B2 (ja) |
| EP (1) | EP2087003A2 (ja) |
| JP (1) | JP2010509937A (ja) |
| WO (1) | WO2008140570A2 (ja) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100062418A1 (en) * | 2006-11-22 | 2010-03-11 | Mach Patrick A | Inactivated and dried biological preparations |
| US20100099115A1 (en) | 2006-11-22 | 2010-04-22 | Mach Patrick A | Systems and methods for preparing and analyzing samples |
| WO2008131063A1 (en) * | 2007-04-19 | 2008-10-30 | 3M Innovative Properties Company | Methods of use of solid support material for binding biomolecules |
| US20100209946A1 (en) * | 2007-04-19 | 2010-08-19 | Naiyong Jing | Uses of water-dispersible silica nanoparticles for attaching biomolecules |
| WO2009067595A1 (en) * | 2007-11-20 | 2009-05-28 | 3M Innovative Properties Company | Method of analyzing a sample for a bacterium using diacetylene-containing polymer sensor |
| KR20170102039A (ko) | 2009-04-03 | 2017-09-06 | 유니버시티 오브 시카고 | 단백질 Ａ(ＳｐＡ) 변이체와 관련된 조성물 및 방법 |
| AU2011274367B2 (en) | 2010-07-02 | 2015-04-23 | The University Of Chicago | Compositions and methods related to protein A (SpA) variants |
| CA2845259A1 (en) | 2011-08-15 | 2013-02-21 | The University Of Chicago | Compositions and methods related to antibodies to staphylococcal protein a |
| US9988439B2 (en) | 2011-12-23 | 2018-06-05 | Nicholas B. Lydon | Immunoglobulins and variants directed against pathogenic microbes |
| WO2013096948A1 (en) | 2011-12-23 | 2013-06-27 | Lydon Nicholas B | Immunoglobulins and variants directed against pathogenic microbes |
| AU2015271749B2 (en) | 2014-06-03 | 2018-03-01 | Xbiotech Inc. | Compositions and methods for treating and preventing Staphylococcus aureus infections |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4741900A (en) | 1982-11-16 | 1988-05-03 | Cytogen Corporation | Antibody-metal ion complexes |
| GB8426463D0 (en) | 1984-10-19 | 1984-11-28 | Technology Licence Co Ltd | Monoclonal antibodies |
| JPS63273495A (ja) | 1987-04-30 | 1988-11-10 | Sekisui Chem Co Ltd | 抗プロテインａ単クロ−ン性抗体とその製法，および該抗体を用いるプロテインａの測定方法 |
| ATE151110T1 (de) | 1988-09-02 | 1997-04-15 | Protein Eng Corp | Herstellung und auswahl von rekombinantproteinen mit verschiedenen bindestellen |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5750373A (en) | 1990-12-03 | 1998-05-12 | Genentech, Inc. | Enrichment method for variant proteins having altered binding properties, M13 phagemids, and growth hormone variants |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| WO1992020791A1 (en) | 1990-07-10 | 1992-11-26 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
| CA2105300C (en) | 1991-03-01 | 2008-12-23 | Robert C. Ladner | Process for the development of binding mini-proteins |
| JP3672306B2 (ja) | 1991-04-10 | 2005-07-20 | ザ スクリップス リサーチ インスティテュート | ファージミドを使用するヘテロ二量体受容体ライブラリー |
| DE4122599C2 (de) | 1991-07-08 | 1993-11-11 | Deutsches Krebsforsch | Phagemid zum Screenen von Antikörpern |
| US6994855B1 (en) | 1994-08-22 | 2006-02-07 | The Provost Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin | S. aureus fibrinogen binding protein gene |
| US6008341A (en) | 1994-08-22 | 1999-12-28 | The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin | S. aureus fibrinogen binding protein gene |
| US5594116A (en) | 1995-11-08 | 1997-01-14 | Promega Corporation | Tryptase polyclonal antibody and purification method for use in human tryptase immunoassay |
| FR2746398B1 (fr) | 1996-03-21 | 1998-04-30 | Bio Merieux | Anticorps specifique de staphylococcus aureaus, et utilisations |
| CN100359327C (zh) | 2001-06-15 | 2008-01-02 | 英希比泰克斯公司 | 识别凝血酶阴性的葡萄球菌和金黄色葡萄球菌的表面蛋白的交叉反应性单克隆抗体和多克隆抗体 |
| DE60231651D1 (de) | 2001-12-21 | 2009-04-30 | Immunex Corp | Proteinreinigungsverfahren |
| US20060051820A1 (en) | 2002-11-22 | 2006-03-09 | Daiichi Pure Chemicals Co., Ltd. | Method of examing staphylococcus aureus |
| JP2010510525A (ja) * | 2006-11-22 | 2010-04-02 | スリーエム イノベイティブ プロパティズ カンパニー | 流体の抗体を含有する装置及び方法 |
-
2006
- 2006-11-22 US US11/562,759 patent/US7488807B2/en not_active Expired - Fee Related
-
2007
- 2007-11-15 EP EP07874277A patent/EP2087003A2/en not_active Withdrawn
- 2007-11-15 WO PCT/US2007/084736 patent/WO2008140570A2/en active Application Filing
- 2007-11-15 JP JP2009538451A patent/JP2010509937A/ja not_active Withdrawn
-
2009
- 2009-01-20 US US12/356,241 patent/US20090162902A1/en not_active Abandoned
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