JP2010509937A - プロテインa選択性を有する抗体 - Google Patents
プロテインa選択性を有する抗体 Download PDFInfo
- Publication number
- JP2010509937A JP2010509937A JP2009538451A JP2009538451A JP2010509937A JP 2010509937 A JP2010509937 A JP 2010509937A JP 2009538451 A JP2009538451 A JP 2009538451A JP 2009538451 A JP2009538451 A JP 2009538451A JP 2010509937 A JP2010509937 A JP 2010509937A
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- antigen
- cell line
- monoclonal antibody
- binding fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Gram-positive bacteria
- C07K16/1271—Micrococcaceae (F); Staphylococcaceae (F), e.g. Staphylococcus (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/562,759 US7488807B2 (en) | 2006-11-22 | 2006-11-22 | Antibody with protein A selectivity |
| PCT/US2007/084736 WO2008140570A2 (en) | 2006-11-22 | 2007-11-15 | Antibody with protein a selectivity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010509937A true JP2010509937A (ja) | 2010-04-02 |
| JP2010509937A5 JP2010509937A5 (enExample) | 2011-01-06 |
Family
ID=39417386
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009538451A Withdrawn JP2010509937A (ja) | 2006-11-22 | 2007-11-15 | プロテインa選択性を有する抗体 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US7488807B2 (enExample) |
| EP (1) | EP2087003A2 (enExample) |
| JP (1) | JP2010509937A (enExample) |
| WO (1) | WO2008140570A2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100099115A1 (en) | 2006-11-22 | 2010-04-22 | Mach Patrick A | Systems and methods for preparing and analyzing samples |
| WO2008136861A2 (en) * | 2006-11-22 | 2008-11-13 | 3M Innovative Properties Company | Inactivated and dried biological preparations |
| WO2008131063A1 (en) * | 2007-04-19 | 2008-10-30 | 3M Innovative Properties Company | Methods of use of solid support material for binding biomolecules |
| WO2009009188A2 (en) * | 2007-04-19 | 2009-01-15 | 3M Innovative Properties Company | Uses of water-dispersible silica nanoparticles for attaching biomolecules |
| JP2011504236A (ja) * | 2007-11-20 | 2011-02-03 | スリーエム イノベイティブ プロパティズ カンパニー | ジアセチレンを含むポリマーセンサーを用いる細菌試料の分析方法 |
| PT3281947T (pt) | 2009-04-03 | 2020-05-07 | Univ Chicago | Composições e métodos relacionados com variantes da proteína a (spa) |
| EP2588120B1 (en) | 2010-07-02 | 2017-11-15 | The University of Chicago | Compositions and methods related to protein a (spa) variants |
| EP2744517B1 (en) * | 2011-08-15 | 2019-03-13 | The University of Chicago | Compositions and methods related to antibodies to staphylococcal protein a |
| EP2793944B1 (en) | 2011-12-23 | 2025-10-08 | Nicholas B. Lydon | Immunoglobulins and variants directed against pathogenic microbes |
| US9988439B2 (en) | 2011-12-23 | 2018-06-05 | Nicholas B. Lydon | Immunoglobulins and variants directed against pathogenic microbes |
| PH12018501429B1 (en) | 2014-06-03 | 2022-04-27 | Xbiotech Inc | Compositions and methods for treating and preventing staphylococcus aureus infections |
| AU2019384790A1 (en) * | 2018-11-21 | 2021-03-18 | Regeneron Pharmaceuticals, Inc. | Anti-staphylococcus antibodies and uses thereof |
| BR112021022902A2 (pt) | 2019-05-14 | 2022-01-25 | Univ Chicago | Métodos e composições que compreendem variantes de proteína a staphylococcus (spa) |
| WO2021051136A1 (en) | 2019-09-13 | 2021-03-18 | The University Of Chicago | Methods and compositions for treating staphylococcal infections |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4741900A (en) * | 1982-11-16 | 1988-05-03 | Cytogen Corporation | Antibody-metal ion complexes |
| GB8426463D0 (en) | 1984-10-19 | 1984-11-28 | Technology Licence Co Ltd | Monoclonal antibodies |
| JPS63273495A (ja) | 1987-04-30 | 1988-11-10 | Sekisui Chem Co Ltd | 抗プロテインa単クロ−ン性抗体とその製法,および該抗体を用いるプロテインaの測定方法 |
| US5223409A (en) * | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| EP1541682A3 (en) | 1988-09-02 | 2005-07-06 | Dyax Corp. | Generation and selection of recombinant varied binding proteins |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| JPH06508511A (ja) | 1990-07-10 | 1994-09-29 | ケンブリッジ アンティボディー テクノロジー リミティド | 特異的な結合ペアーの構成員の製造方法 |
| DE69129154T2 (de) | 1990-12-03 | 1998-08-20 | Genentech, Inc., South San Francisco, Calif. | Verfahren zur anreicherung von proteinvarianten mit geänderten bindungseigenschaften |
| DE69233769D1 (de) | 1991-03-01 | 2009-09-24 | Dyax Corp | Chimäres Protein mit Mikroprotein mit zwei oder mehr Disulfidbindungen und Ausgestaltungen davon |
| ATE414768T1 (de) | 1991-04-10 | 2008-12-15 | Scripps Research Inst | Bibliotheken heterodimerer rezeptoren mittels phagemiden |
| DE4122599C2 (de) | 1991-07-08 | 1993-11-11 | Deutsches Krebsforsch | Phagemid zum Screenen von Antikörpern |
| US6008341A (en) * | 1994-08-22 | 1999-12-28 | The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin | S. aureus fibrinogen binding protein gene |
| US6994855B1 (en) * | 1994-08-22 | 2006-02-07 | The Provost Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin | S. aureus fibrinogen binding protein gene |
| US5594116A (en) * | 1995-11-08 | 1997-01-14 | Promega Corporation | Tryptase polyclonal antibody and purification method for use in human tryptase immunoassay |
| FR2746398B1 (fr) * | 1996-03-21 | 1998-04-30 | Bio Merieux | Anticorps specifique de staphylococcus aureaus, et utilisations |
| CA2450939C (en) * | 2001-06-15 | 2012-11-06 | The Provost Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin | Cross-reactive monoclonal and polyclonal antibodies which recognize surface proteins from coagulase-negative staphylococci and staphylococcus aureus |
| MXPA04006053A (es) * | 2001-12-21 | 2005-03-31 | Immunex Corp | Metodos para purificacion de proteina. |
| AU2003284643A1 (en) * | 2002-11-22 | 2004-06-18 | Daiichi Pure Chemicals Co., Ltd. | Method of examining staphylococcus aureus |
| EP2095123A2 (en) * | 2006-11-22 | 2009-09-02 | 3M Innovative Properties Company | Fluidic antibody-containing devices and methods |
-
2006
- 2006-11-22 US US11/562,759 patent/US7488807B2/en not_active Expired - Fee Related
-
2007
- 2007-11-15 EP EP07874277A patent/EP2087003A2/en not_active Withdrawn
- 2007-11-15 WO PCT/US2007/084736 patent/WO2008140570A2/en not_active Ceased
- 2007-11-15 JP JP2009538451A patent/JP2010509937A/ja not_active Withdrawn
-
2009
- 2009-01-20 US US12/356,241 patent/US20090162902A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008140570A2 (en) | 2008-11-20 |
| WO2008140570A3 (en) | 2009-03-05 |
| EP2087003A2 (en) | 2009-08-12 |
| US20080118937A1 (en) | 2008-05-22 |
| US7488807B2 (en) | 2009-02-10 |
| US20090162902A1 (en) | 2009-06-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20101112 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20101112 |
|
| A761 | Written withdrawal of application |
Free format text: JAPANESE INTERMEDIATE CODE: A761 Effective date: 20110406 |