JP2010509937A - プロテインａ選択性を有する抗体 - Google Patents

プロテインａ選択性を有する抗体 Download PDF

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Publication number
JP2010509937A
JP2010509937A JP2009538451A JP2009538451A JP2010509937A JP 2010509937 A JP2010509937 A JP 2010509937A JP 2009538451 A JP2009538451 A JP 2009538451A JP 2009538451 A JP2009538451 A JP 2009538451A JP 2010509937 A JP2010509937 A JP 2010509937A
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JP
Japan
Prior art keywords
antibody
antigen
cell line
monoclonal antibody
binding fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2009538451A
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English (en)
Japanese (ja)
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JP2010509937A5 (enExample
Inventor
エー． マッチ，パトリック
エス． レイフ−ウェンナー，マーラ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
3M Innovative Properties Co
Original Assignee
3M Innovative Properties Co
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Publication date
Application filed by 3M Innovative Properties Co filed Critical 3M Innovative Properties Co
Publication of JP2010509937A publication Critical patent/JP2010509937A/ja
Publication of JP2010509937A5 publication Critical patent/JP2010509937A5/ja
Withdrawn legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Gram-positive bacteria
    • C07K16/1271—Micrococcaceae (F); Staphylococcaceae (F), e.g. Staphylococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2009538451A 2006-11-22 2007-11-15 プロテインａ選択性を有する抗体 Withdrawn JP2010509937A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/562,759 US7488807B2 (en) 2006-11-22 2006-11-22 Antibody with protein A selectivity
PCT/US2007/084736 WO2008140570A2 (en) 2006-11-22 2007-11-15 Antibody with protein a selectivity

Publications (2)

Publication Number Publication Date
JP2010509937A true JP2010509937A (ja) 2010-04-02
JP2010509937A5 JP2010509937A5 (enExample) 2011-01-06

Family

ID=39417386

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009538451A Withdrawn JP2010509937A (ja) 2006-11-22 2007-11-15 プロテインａ選択性を有する抗体

Country Status (4)

Country Link
US (2) US7488807B2 (enExample)
EP (1) EP2087003A2 (enExample)
JP (1) JP2010509937A (enExample)
WO (1) WO2008140570A2 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100099115A1 (en) 2006-11-22 2010-04-22 Mach Patrick A Systems and methods for preparing and analyzing samples
WO2008136861A2 (en) * 2006-11-22 2008-11-13 3M Innovative Properties Company Inactivated and dried biological preparations
WO2008131063A1 (en) * 2007-04-19 2008-10-30 3M Innovative Properties Company Methods of use of solid support material for binding biomolecules
CN101663581A (zh) * 2007-04-19 2010-03-03 3M创新有限公司 水分散性二氧化硅纳米颗粒在连接生物分子方面的用途
EP2220500A4 (en) * 2007-11-20 2010-12-15 3M Innovative Properties Co METHOD FOR ANALYZING A BACTERIUM SAMPLE USING A POLYMER DETECTOR CONTAINING DIACETYLENE
EP3281947B1 (en) 2009-04-03 2020-02-12 The University of Chicago Compositions and methods related to protein a (spa) variants
ES2655701T3 (es) 2010-07-02 2018-02-21 The University Of Chicago Composiciones y métodos relacionados con variantes de la proteína A (SpA)
US9556281B2 (en) 2011-08-15 2017-01-31 The University Of Chicago Compositions and methods related to antibodies to staphylococcal protein A
EP2793944B1 (en) 2011-12-23 2025-10-08 Nicholas B. Lydon Immunoglobulins and variants directed against pathogenic microbes
US9988439B2 (en) 2011-12-23 2018-06-05 Nicholas B. Lydon Immunoglobulins and variants directed against pathogenic microbes
NZ726911A (en) 2014-06-03 2023-01-27 Xbiotech Inc Compositions and methods for treating and preventing staphylococcus aureus infections
MX2021005863A (es) * 2018-11-21 2021-07-16 Regeneron Pharma Anticuerpos antiestafilococo y usos de estos.
AU2020273471B2 (en) 2019-05-14 2026-05-07 The University Of Chicago Methods and compositions comprising Staphylococcus protein A (SpA) variants
US12528882B2 (en) 2019-09-13 2026-01-20 The University Of Chicago Methods and compositions for treating staphylococcal infections

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4741900A (en) 1982-11-16 1988-05-03 Cytogen Corporation Antibody-metal ion complexes
GB8426463D0 (en) 1984-10-19 1984-11-28 Technology Licence Co Ltd Monoclonal antibodies
JPS63273495A (ja) 1987-04-30 1988-11-10 Sekisui Chem Co Ltd 抗プロテインａ単クロ−ン性抗体とその製法，および該抗体を用いるプロテインａの測定方法
EP0768377A1 (en) 1988-09-02 1997-04-16 Protein Engineering Corporation Generation and selection of recombinant varied binding proteins
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
CA2109602C (en) 1990-07-10 2002-10-01 Gregory P. Winter Methods for producing members of specific binding pairs
ES2113940T3 (es) 1990-12-03 1998-05-16 Genentech Inc Metodo de enriquecimiento para variantes de proteinas con propiedades de union alteradas.
DE69233769D1 (de) 1991-03-01 2009-09-24 Dyax Corp Chimäres Protein mit Mikroprotein mit zwei oder mehr Disulfidbindungen und Ausgestaltungen davon
AU662148B2 (en) 1991-04-10 1995-08-24 Scripps Research Institute, The Heterodimeric receptor libraries using phagemids
DE4122599C2 (de) 1991-07-08 1993-11-11 Deutsches Krebsforsch Phagemid zum Screenen von Antikörpern
US6008341A (en) 1994-08-22 1999-12-28 The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin S. aureus fibrinogen binding protein gene
US6994855B1 (en) 1994-08-22 2006-02-07 The Provost Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin S. aureus fibrinogen binding protein gene
US5594116A (en) 1995-11-08 1997-01-14 Promega Corporation Tryptase polyclonal antibody and purification method for use in human tryptase immunoassay
FR2746398B1 (fr) 1996-03-21 1998-04-30 Bio Merieux Anticorps specifique de staphylococcus aureaus, et utilisations
WO2002102829A2 (en) 2001-06-15 2002-12-27 Inhibitex, Inc. Cross-reactive monoclonal and polyclonal antibodies which recognize surface proteins from coagulase-negative staphylococci and staphylococcus aureus
PL374311A1 (en) 2001-12-21 2005-10-03 Immunex Corporation Methods for purifying protein
AU2003284643A1 (en) * 2002-11-22 2004-06-18 Daiichi Pure Chemicals Co., Ltd. Method of examining staphylococcus aureus
WO2008064232A2 (en) * 2006-11-22 2008-05-29 3M Innovative Properties Company Fluidic antibody-containing devices and methods

Also Published As

Publication number Publication date
WO2008140570A2 (en) 2008-11-20
US20090162902A1 (en) 2009-06-25
US7488807B2 (en) 2009-02-10
EP2087003A2 (en) 2009-08-12
WO2008140570A3 (en) 2009-03-05
US20080118937A1 (en) 2008-05-22

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