JP2010508846A5 - - Google Patents
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- Publication number
- JP2010508846A5 JP2010508846A5 JP2009536303A JP2009536303A JP2010508846A5 JP 2010508846 A5 JP2010508846 A5 JP 2010508846A5 JP 2009536303 A JP2009536303 A JP 2009536303A JP 2009536303 A JP2009536303 A JP 2009536303A JP 2010508846 A5 JP2010508846 A5 JP 2010508846A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- stem
- cardiomyocytes
- progenitor
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000000130 stem cell Anatomy 0.000 claims 19
- 238000000034 method Methods 0.000 claims 18
- 210000004413 cardiac myocyte Anatomy 0.000 claims 8
- 210000004027 cell Anatomy 0.000 claims 7
- 229920001184 polypeptide Polymers 0.000 claims 6
- 102000004196 processed proteins & peptides Human genes 0.000 claims 6
- 108090000765 processed proteins & peptides Proteins 0.000 claims 6
- 239000003795 chemical substances by application Substances 0.000 claims 4
- 210000005003 heart tissue Anatomy 0.000 claims 4
- 239000000758 substrate Substances 0.000 claims 4
- 102000015735 Beta-catenin Human genes 0.000 claims 3
- 108060000903 Beta-catenin Proteins 0.000 claims 3
- 125000003275 alpha amino acid group Chemical group 0.000 claims 3
- 102000039446 nucleic acids Human genes 0.000 claims 3
- 108020004707 nucleic acids Proteins 0.000 claims 3
- 150000007523 nucleic acids Chemical group 0.000 claims 3
- 230000004069 differentiation Effects 0.000 claims 2
- 238000000338 in vitro Methods 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 239000002243 precursor Substances 0.000 claims 2
- 241000702421 Dependoparvovirus Species 0.000 claims 1
- 102000013814 Wnt Human genes 0.000 claims 1
- 230000004156 Wnt signaling pathway Effects 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 238000000151 deposition Methods 0.000 claims 1
- 210000002242 embryoid body Anatomy 0.000 claims 1
- 210000005260 human cell Anatomy 0.000 claims 1
- 239000003446 ligand Substances 0.000 claims 1
- 239000003550 marker Substances 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- 230000002107 myocardial effect Effects 0.000 claims 1
- 230000010349 pulsation Effects 0.000 claims 1
- 230000003612 virological effect Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85814506P | 2006-11-09 | 2006-11-09 | |
| PCT/US2007/023588 WO2008060446A2 (en) | 2006-11-09 | 2007-11-09 | Methods for inducing cardiomyogenesis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010508846A JP2010508846A (ja) | 2010-03-25 |
| JP2010508846A5 true JP2010508846A5 (https=) | 2010-12-24 |
Family
ID=39402201
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009536303A Pending JP2010508846A (ja) | 2006-11-09 | 2007-11-09 | 心筋形成を誘発するための方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20100129915A1 (https=) |
| EP (1) | EP2084263A4 (https=) |
| JP (1) | JP2010508846A (https=) |
| CN (1) | CN101573442A (https=) |
| WO (1) | WO2008060446A2 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010007031A2 (en) * | 2008-07-14 | 2010-01-21 | Novartis Ag | Methods for improving cardiac differentiation of human embryonic stem cells |
| CN102498399A (zh) * | 2009-05-20 | 2012-06-13 | 卡迪欧参生物科技有限公司 | 哺乳动物细胞的心脏生长潜能的确定方法 |
| EP2499260B1 (en) * | 2009-11-10 | 2017-08-23 | Nestec S.A. | Heart aging biomarkers and methods of use |
| US9273286B2 (en) * | 2010-06-13 | 2016-03-01 | Institute Of Biophysics, Chinese Academy Of Sciences | Methods and compositions for preparing cardiomyocytes from stem cells and uses thereof |
| US8951798B2 (en) * | 2011-10-13 | 2015-02-10 | Wisconsin Alumni Research Foundation | Generation of cardiomyocytes from human pluripotent stem cells |
| WO2013159349A1 (en) * | 2012-04-27 | 2013-10-31 | Curegenix Inc. | Method for producing cardiomyocytes |
| CN104508121B (zh) | 2012-07-23 | 2018-01-19 | 中国科学院生物物理研究所 | 体外诱导多能干细胞分化为心室肌细胞的方法 |
| EP3065785A4 (en) * | 2013-11-06 | 2017-11-15 | The Texas A&M University System | Cardiac myofibril induction |
| CN108779441A (zh) * | 2016-03-15 | 2018-11-09 | 学校法人庆应义塾 | 由多能干细胞制造心脏祖细胞和心肌细胞的制造方法 |
| JP2021518113A (ja) * | 2018-03-16 | 2021-08-02 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 心筋細胞を生成及び増殖させるためのwntアゴニスト、並びに生理活性脂質を用いた試薬及び方法 |
| CN110448675A (zh) * | 2019-09-20 | 2019-11-15 | 苏州大学 | 一种放射性皮肤损伤防治药物 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4963489A (en) * | 1987-04-14 | 1990-10-16 | Marrow-Tech, Inc. | Three-dimensional cell and tissue culture system |
| US5919449A (en) * | 1995-05-30 | 1999-07-06 | Diacrin, Inc. | Porcine cardiomyocytes and their use in treatment of insufficient cardiac function |
| CA2296704C (en) * | 1997-07-14 | 2010-10-19 | Osiris Therapeutics, Inc. | Cardiac muscle regeneration using mesenchymal stem cells |
| US20030007954A1 (en) * | 1999-04-12 | 2003-01-09 | Gail K. Naughton | Methods for using a three-dimensional stromal tissue to promote angiogenesis |
| US20040014209A1 (en) * | 2002-01-23 | 2004-01-22 | Lassar Andrew B. | Compositions and methods for modulating cell differentiation |
| US20060030541A1 (en) * | 2002-04-05 | 2006-02-09 | Proskelia | Genes involved in osteogenesis, and methods of use |
| WO2004094610A2 (en) * | 2003-04-21 | 2004-11-04 | Baylor College Of Medicine | Wnt as a factor for cardiac myogenesis |
| US7850960B2 (en) * | 2004-12-30 | 2010-12-14 | University Of Washington | Methods for regulation of stem cells |
| WO2006124356A2 (en) * | 2005-05-16 | 2006-11-23 | The Rockefeller University | Method for isolating dermal papilla cells and uses thereof |
| EP2014766A4 (en) * | 2006-04-28 | 2009-12-02 | Asubio Pharma Co Ltd | METHOD FOR DIFFERENTIATING INDICATION OF A MYOCARDIAL CELL FROM A PLURIPOTENTIAL STEM CELL |
-
2007
- 2007-11-09 WO PCT/US2007/023588 patent/WO2008060446A2/en not_active Ceased
- 2007-11-09 CN CNA2007800488155A patent/CN101573442A/zh active Pending
- 2007-11-09 JP JP2009536303A patent/JP2010508846A/ja active Pending
- 2007-11-09 US US12/513,657 patent/US20100129915A1/en not_active Abandoned
- 2007-11-09 EP EP07867393A patent/EP2084263A4/en not_active Withdrawn
-
2015
- 2015-07-30 US US14/814,452 patent/US20160194608A1/en not_active Abandoned
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