CN101573442A - 诱导心肌细胞形成的方法 - Google Patents

诱导心肌细胞形成的方法 Download PDF

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Publication number
CN101573442A
CN101573442A CNA2007800488155A CN200780048815A CN101573442A CN 101573442 A CN101573442 A CN 101573442A CN A2007800488155 A CNA2007800488155 A CN A2007800488155A CN 200780048815 A CN200780048815 A CN 200780048815A CN 101573442 A CN101573442 A CN 101573442A
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Chinese (zh)
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D·斯里瓦斯塔瓦
权喆颜
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J David Gladstone Institutes
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J David Gladstone Institutes
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657—Cardiomyocytes; Heart cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40—Regulators of development
    • C12N2501/415—Wnt; Frizzeled

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
CNA2007800488155A 2006-11-09 2007-11-09 诱导心肌细胞形成的方法 Pending CN101573442A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85814506P 2006-11-09 2006-11-09
US60/858,145 2006-11-09

Publications (1)

Publication Number Publication Date
CN101573442A true CN101573442A (zh) 2009-11-04

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Family Applications (1)

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CNA2007800488155A Pending CN101573442A (zh) 2006-11-09 2007-11-09 诱导心肌细胞形成的方法

Country Status (5)

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US (2) US20100129915A1 (https=)
EP (1) EP2084263A4 (https=)
JP (1) JP2010508846A (https=)
CN (1) CN101573442A (https=)
WO (1) WO2008060446A2 (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102695807A (zh) * 2009-11-10 2012-09-26 雀巢产品技术援助有限公司 心脏衰老生物标志物及其用途
WO2013159349A1 (en) * 2012-04-27 2013-10-31 Curegenix Inc. Method for producing cardiomyocytes
CN108779441A (zh) * 2016-03-15 2018-11-09 学校法人庆应义塾 由多能干细胞制造心脏祖细胞和心肌细胞的制造方法
CN110448675A (zh) * 2019-09-20 2019-11-15 苏州大学 一种放射性皮肤损伤防治药物

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010007031A2 (en) * 2008-07-14 2010-01-21 Novartis Ag Methods for improving cardiac differentiation of human embryonic stem cells
CN102498399A (zh) * 2009-05-20 2012-06-13 卡迪欧参生物科技有限公司 哺乳动物细胞的心脏生长潜能的确定方法
US9273286B2 (en) * 2010-06-13 2016-03-01 Institute Of Biophysics, Chinese Academy Of Sciences Methods and compositions for preparing cardiomyocytes from stem cells and uses thereof
US8951798B2 (en) * 2011-10-13 2015-02-10 Wisconsin Alumni Research Foundation Generation of cardiomyocytes from human pluripotent stem cells
CN104508121B (zh) 2012-07-23 2018-01-19 中国科学院生物物理研究所 体外诱导多能干细胞分化为心室肌细胞的方法
EP3065785A4 (en) * 2013-11-06 2017-11-15 The Texas A&M University System Cardiac myofibril induction
JP2021518113A (ja) * 2018-03-16 2021-08-02 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 心筋細胞を生成及び増殖させるためのｗｎｔアゴニスト、並びに生理活性脂質を用いた試薬及び方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4963489A (en) * 1987-04-14 1990-10-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
US5919449A (en) * 1995-05-30 1999-07-06 Diacrin, Inc. Porcine cardiomyocytes and their use in treatment of insufficient cardiac function
CA2296704C (en) * 1997-07-14 2010-10-19 Osiris Therapeutics, Inc. Cardiac muscle regeneration using mesenchymal stem cells
US20030007954A1 (en) * 1999-04-12 2003-01-09 Gail K. Naughton Methods for using a three-dimensional stromal tissue to promote angiogenesis
US20040014209A1 (en) * 2002-01-23 2004-01-22 Lassar Andrew B. Compositions and methods for modulating cell differentiation
US20060030541A1 (en) * 2002-04-05 2006-02-09 Proskelia Genes involved in osteogenesis, and methods of use
WO2004094610A2 (en) * 2003-04-21 2004-11-04 Baylor College Of Medicine Wnt as a factor for cardiac myogenesis
US7850960B2 (en) * 2004-12-30 2010-12-14 University Of Washington Methods for regulation of stem cells
WO2006124356A2 (en) * 2005-05-16 2006-11-23 The Rockefeller University Method for isolating dermal papilla cells and uses thereof
EP2014766A4 (en) * 2006-04-28 2009-12-02 Asubio Pharma Co Ltd METHOD FOR DIFFERENTIATING INDICATION OF A MYOCARDIAL CELL FROM A PLURIPOTENTIAL STEM CELL

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102695807A (zh) * 2009-11-10 2012-09-26 雀巢产品技术援助有限公司 心脏衰老生物标志物及其用途
CN102695807B (zh) * 2009-11-10 2016-02-24 雀巢产品技术援助有限公司 心脏衰老生物标志物及其用途
WO2013159349A1 (en) * 2012-04-27 2013-10-31 Curegenix Inc. Method for producing cardiomyocytes
CN108779441A (zh) * 2016-03-15 2018-11-09 学校法人庆应义塾 由多能干细胞制造心脏祖细胞和心肌细胞的制造方法
CN110448675A (zh) * 2019-09-20 2019-11-15 苏州大学 一种放射性皮肤损伤防治药物

Also Published As

Publication number Publication date
JP2010508846A (ja) 2010-03-25
WO2008060446A9 (en) 2008-07-10
EP2084263A2 (en) 2009-08-05
US20100129915A1 (en) 2010-05-27
WO2008060446A2 (en) 2008-05-22
WO2008060446A3 (en) 2008-11-13
EP2084263A4 (en) 2011-06-22
US20160194608A1 (en) 2016-07-07

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Application publication date: 20091104