JP2010506567A - 新規骨石灰化タンパク質発現系、およびその細胞内シグナル伝達経路の試験方法 - Google Patents
新規骨石灰化タンパク質発現系、およびその細胞内シグナル伝達経路の試験方法 Download PDFInfo
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
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- A—HUMAN NECESSITIES
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5041—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving analysis of members of signalling pathways
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
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- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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- C12N2503/00—Use of cells in diagnostics
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- C12N2510/00—Genetically modified cells
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- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
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- Urology & Nephrology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
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- General Physics & Mathematics (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/546,891 US7741117B2 (en) | 1997-04-30 | 2006-10-12 | Bone mineralization protein expression systems, and methods of studying intracellular signaling pathways induced thereby |
| PCT/US2007/080910 WO2008045919A2 (en) | 2006-10-12 | 2007-10-10 | Novel bone mineralization protein expression systems, and methods of studying their intracellular signaling pathways |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010506567A true JP2010506567A (ja) | 2010-03-04 |
| JP2010506567A5 JP2010506567A5 (enExample) | 2010-07-01 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009532547A Pending JP2010506567A (ja) | 2006-10-12 | 2007-10-10 | 新規骨石灰化タンパク質発現系、およびその細胞内シグナル伝達経路の試験方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US7741117B2 (enExample) |
| EP (1) | EP2064320A2 (enExample) |
| JP (1) | JP2010506567A (enExample) |
| WO (1) | WO2008045919A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018522597A (ja) * | 2015-08-21 | 2018-08-16 | 42・ライフ・サイエンシズ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング・ウント・コンパニー・コマンディトゲゼルシャフト | ハイブリダイゼーションのための組成物および方法 |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090110637A1 (en) * | 2007-10-26 | 2009-04-30 | Warsaw Orthopedic, Inc. | LMP and Regulation of Tissue Growth |
| US20150148292A1 (en) | 2012-07-09 | 2015-05-28 | Emory University | Bone morphogenetic protein pathway activation, compositions for ossification, and methods related thereto |
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| US2006A (en) * | 1841-03-16 | Clamp for crimping leather | ||
| US5504192A (en) * | 1993-12-13 | 1996-04-02 | The Regents Of The University Of California | Human insulin receptor endocytic code binding protein |
| US20030225021A1 (en) * | 2001-11-14 | 2003-12-04 | Mckay William F. | Methods of inducing the expression of bone morphogenetic proteins (BMPs) and transforming growth factor-beta proteins (TGF-betas) in cells |
| US7923250B2 (en) * | 1997-07-30 | 2011-04-12 | Warsaw Orthopedic, Inc. | Methods of expressing LIM mineralization protein in non-osseous cells |
| CA2297489A1 (en) * | 1997-07-30 | 1999-02-11 | Emory University | Novel bone mineralization proteins, dna, vectors, expression systems |
| JP4615736B2 (ja) * | 1999-04-30 | 2011-01-19 | エモリー・ユニバーシテイ | Lim鉱質化タンパク質スプライス変異型 |
| US7504374B2 (en) * | 2000-10-24 | 2009-03-17 | Warsaw Orthopedic, Inc. | Method for inducing deposition and maturation of bone comprising a co-therapeutic regimen of LMP-1 and BMP-2 |
| US7241732B2 (en) * | 2001-09-20 | 2007-07-10 | University Of Rochester | Compositions and methods involved in bone growth |
| EP1590038A4 (en) * | 2003-01-31 | 2006-12-06 | Univ Rochester | LIGHTING SOUND FOR GENTRANSION ACTIVATED BY ULTRAVIOLETTIC LIGHT |
| GB0302315D0 (en) | 2003-02-01 | 2003-03-05 | Univ East Anglia | Novel therapeutic target |
| WO2005016368A2 (en) * | 2003-08-19 | 2005-02-24 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Use of phosphophoryn for inducing biomineralization and bone regeneration |
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2006
- 2006-10-12 US US11/546,891 patent/US7741117B2/en not_active Expired - Lifetime
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2007
- 2007-10-10 WO PCT/US2007/080910 patent/WO2008045919A2/en not_active Ceased
- 2007-10-10 EP EP07868402A patent/EP2064320A2/en not_active Withdrawn
- 2007-10-10 JP JP2009532547A patent/JP2010506567A/ja active Pending
Non-Patent Citations (1)
| Title |
|---|
| JPN6012046887; J. Biol. Chem. Vol.281, No.25, 200606, p.17212-17219 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018522597A (ja) * | 2015-08-21 | 2018-08-16 | 42・ライフ・サイエンシズ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング・ウント・コンパニー・コマンディトゲゼルシャフト | ハイブリダイゼーションのための組成物および方法 |
| JP2020089376A (ja) * | 2015-08-21 | 2020-06-11 | 42・ライフ・サイエンシズ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング・ウント・コンパニー・コマンディトゲゼルシャフト | ハイブリダイゼーションのための組成物および方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008045919A3 (en) | 2008-10-23 |
| US20080254001A9 (en) | 2008-10-16 |
| US20080089866A1 (en) | 2008-04-17 |
| US7741117B2 (en) | 2010-06-22 |
| WO2008045919A2 (en) | 2008-04-17 |
| EP2064320A2 (en) | 2009-06-03 |
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