JP2010501074A - グリカンのデータマイニングシステム - Google Patents

グリカンのデータマイニングシステム Download PDF

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Publication number
JP2010501074A
JP2010501074A JP2009524675A JP2009524675A JP2010501074A JP 2010501074 A JP2010501074 A JP 2010501074A JP 2009524675 A JP2009524675 A JP 2009524675A JP 2009524675 A JP2009524675 A JP 2009524675A JP 2010501074 A JP2010501074 A JP 2010501074A
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JP
Japan
Prior art keywords
binding
glycan
glycans
type
sialic acid
Prior art date
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Pending
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JP2009524675A
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English (en)
Japanese (ja)
Inventor
ラム サシセカラン,
エス. ラグラム,
マーデバン ベンカタラマン,
サブラマニアン カウンディンヤ,
ラウル ラマン,
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Massachusetts Institute of Technology
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Massachusetts Institute of Technology
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Application filed by Massachusetts Institute of Technology filed Critical Massachusetts Institute of Technology
Publication of JP2010501074A publication Critical patent/JP2010501074A/ja
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pulmonology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Toxicology (AREA)
JP2009524675A 2006-08-14 2007-08-14 グリカンのデータマイニングシステム Pending JP2010501074A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83786806P 2006-08-14 2006-08-14
US83786906P 2006-08-14 2006-08-14
PCT/US2007/018103 WO2008021415A2 (en) 2006-08-14 2007-08-14 Glycan data mining system

Publications (1)

Publication Number Publication Date
JP2010501074A true JP2010501074A (ja) 2010-01-14

Family

ID=39082721

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2009524675A Pending JP2010501074A (ja) 2006-08-14 2007-08-14 グリカンのデータマイニングシステム
JP2009524682A Pending JP2010500880A (ja) 2006-08-14 2007-08-14 ヘマグルチニンポリペプチド、ならびにヘマグルチニンポリペプチドに関連する試薬および方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2009524682A Pending JP2010500880A (ja) 2006-08-14 2007-08-14 ヘマグルチニンポリペプチド、ならびにヘマグルチニンポリペプチドに関連する試薬および方法

Country Status (8)

Country Link
US (3) US20100061990A1 (cg-RX-API-DMAC7.html)
EP (2) EP2049569A4 (cg-RX-API-DMAC7.html)
JP (2) JP2010501074A (cg-RX-API-DMAC7.html)
KR (1) KR20090050056A (cg-RX-API-DMAC7.html)
AU (2) AU2007332987B2 (cg-RX-API-DMAC7.html)
CA (2) CA2660038A1 (cg-RX-API-DMAC7.html)
IL (1) IL196738A0 (cg-RX-API-DMAC7.html)
WO (2) WO2008073161A2 (cg-RX-API-DMAC7.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013541528A (ja) * 2010-09-21 2013-11-14 マサチューセッツ インスティテュート オブ テクノロジー ヒト適応haポリペプチド、ワクチン、およびインフルエンザの処置

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5174014B2 (ja) * 2006-05-30 2013-04-03 ボゴーク,サミュエル レプリキンペプチドおよびその使用
EP2092059A4 (en) * 2006-10-24 2012-03-28 Bogoch Samuel METHOD FOR FORECASTING INFLUENZA EXCESSIONS BY CORRELATION OF AN INCREASED REPLICINE MIRROR IN WHITE SPOT AND / OR TAURA VIRUSES IN CRABES
US20090017052A1 (en) * 2007-01-18 2009-01-15 Samuel Bogoch Methods of determining lethality of pathogens and malignancies involving replikin peak genes
NZ581332A (en) * 2007-05-30 2012-06-29 Samuel Bogoch Synthetic replikin peptides against pathogenic infection of invertebrates in aquaculture
WO2009089119A2 (en) * 2008-01-03 2009-07-16 Massachusetts Institute Of Technology Decoy influenza therapies
CA2711334A1 (en) * 2008-01-03 2009-07-16 Massachusetts Institute Of Technology Hemagglutinin polypeptides, and reagents and methods relating thereto
US20090269367A1 (en) * 2008-04-23 2009-10-29 Samuel Bogoch Methods and compounds for mitigating pathogenic outbreaks using replikin count cycles
US20100144589A1 (en) * 2008-08-08 2010-06-10 Samuel Bogoch Methods of predicting cancer lethality using replikin counts
US9233148B2 (en) * 2009-01-09 2016-01-12 Samuel Bogoch Replikin-based compounds for prevention and treatment of influenza and methods of differentiating infectivity and lethality in influenza
JP5396111B2 (ja) * 2009-03-12 2014-01-22 学校法人慶應義塾 インフルエンザ治療/予防薬
CN103200961B (zh) * 2009-03-27 2017-10-27 中央研究院 抗病毒免疫的方法和组合物
WO2010123519A1 (en) * 2009-04-23 2010-10-28 Samuel Bogoch Replikin-sequences for preventing/treating influenza and determining infectivity/lethality
EP2448596B1 (en) * 2009-07-02 2016-01-06 Massachusetts Institute of Technology Compositions and methods for diagnosing and/or treating influenza infection
CN103977394B (zh) * 2009-07-17 2016-03-09 翰林大学校产学协力团 包含脂质体包胶的寡核苷酸和表位的免疫刺激性组合物
US9320784B2 (en) 2009-08-07 2016-04-26 Samuel Bogoch Peptides shared among lethal cancers and therapeutic compositions comprising said peptides
US20110091493A1 (en) * 2009-10-16 2011-04-21 Northwestern University Vaccine compositions and uses thereof
WO2011094445A1 (en) 2010-01-27 2011-08-04 Massachusetts Institute Of Technology Engineered polypeptide agents for targeted broad spectrum influenza neutralization
SG10201709806VA (en) * 2010-10-04 2017-12-28 Massachusetts Inst Technology Hemagglutinin polypeptides, and reagents and methods relating thereto
TWI537385B (zh) 2010-11-04 2016-06-11 中央研究院 產生具簡單醣基化之表面蛋白質之病毒顆粒的方法
WO2012082634A1 (en) 2010-12-13 2012-06-21 University Of Utah Research Foundation Vaccine antigens that direct immunity to conserved epitopes
CN104144941B (zh) 2012-02-13 2017-06-09 高等教育联邦系统-匹兹堡大学 以计算方式优化的人和禽h5n1流感的广泛反应性抗原
SG11201405317QA (en) * 2012-02-29 2014-09-26 Agency Science Tech & Res Modulating the interaction between zo-2/tjp2 and a snail zinc finger transcription factor family member
CA2871160C (en) 2012-05-10 2023-03-14 Massachusetts Institute Of Technology Agents for influenza neutralization
US9969794B2 (en) 2012-05-10 2018-05-15 Visterra, Inc. HA binding agents
MX358772B (es) 2012-07-19 2018-09-04 Toray Industries Metodo para detectar cancer.
US20140286981A1 (en) 2013-03-14 2014-09-25 Wisconsin Alumni Research Foundation Broadly reactive mosaic peptide for influenza vaccine
WO2014197723A2 (en) 2013-06-05 2014-12-11 Massachusetts Institute Of Technology Human adaptation of h7 ha
EP3916390A1 (en) * 2014-06-04 2021-12-01 Indevr, Inc. Universal capture array for multiplexed subtype-specific quantification and stability determination of influenza proteins
JP6964581B2 (ja) * 2015-08-20 2021-11-10 シーラス ロジック インターナショナル セミコンダクター リミテッド 固定応答フィルタによって部分的に提供されるフィードバック応答を有するフィードバック適応雑音消去(anc)コントローラおよび方法
US10513553B2 (en) 2015-11-13 2019-12-24 Visterra, Inc. Compositions and methods for treating and preventing influenza
AU2017222564A1 (en) 2016-02-24 2018-09-06 Visterra, Inc. Formulations of antibody molecules to influenza virus
ES2991988T3 (es) 2017-10-30 2024-12-05 Takeda Pharmaceuticals Co Detergentes compatibles con el medio ambiente para la inactivación de virus con envoltura lipídica
EP3946613A1 (en) 2019-03-25 2022-02-09 Visterra, Inc. Compositions and methods for treating and preventing influenza
US20230257449A1 (en) 2019-12-11 2023-08-17 Visterra, Inc. Compositions and methods for treating and preventing influenza

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005088310A2 (en) * 2004-03-05 2005-09-22 The Scripps Research Institute High throughput glycan microarrays

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4166452A (en) * 1976-05-03 1979-09-04 Generales Constantine D J Jr Apparatus for testing human responses to stimuli
US4270537A (en) * 1979-11-19 1981-06-02 Romaine Richard A Automatic hypodermic syringe
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4596556A (en) * 1985-03-25 1986-06-24 Bioject, Inc. Hypodermic injection apparatus
US4886499A (en) * 1986-12-18 1989-12-12 Hoffmann-La Roche Inc. Portable injection appliance
GB8704027D0 (en) * 1987-02-20 1987-03-25 Owen Mumford Ltd Syringe needle combination
US4790824A (en) * 1987-06-19 1988-12-13 Bioject, Inc. Non-invasive hypodermic injection device
US4941880A (en) * 1987-06-19 1990-07-17 Bioject, Inc. Pre-filled ampule and non-invasive hypodermic injection device assembly
US4940460A (en) * 1987-06-19 1990-07-10 Bioject, Inc. Patient-fillable and non-invasive hypodermic injection device assembly
US5339163A (en) * 1988-03-16 1994-08-16 Canon Kabushiki Kaisha Automatic exposure control device using plural image plane detection areas
FR2638359A1 (fr) * 1988-11-03 1990-05-04 Tino Dalto Guide de seringue avec reglage de la profondeur de penetration de l'aiguille dans la peau
US5064413A (en) * 1989-11-09 1991-11-12 Bioject, Inc. Needleless hypodermic injection device
US5312335A (en) * 1989-11-09 1994-05-17 Bioject Inc. Needleless hypodermic injection device
US5190521A (en) * 1990-08-22 1993-03-02 Tecnol Medical Products, Inc. Apparatus and method for raising a skin wheal and anesthetizing skin
US5527288A (en) * 1990-12-13 1996-06-18 Elan Medical Technologies Limited Intradermal drug delivery device and method for intradermal delivery of drugs
JPH06247995A (ja) * 1991-06-24 1994-09-06 Asahi Chem Ind Co Ltd 新規なシアリル(α2−6)ラクトテトラオシルセラミド
GB9118204D0 (en) * 1991-08-23 1991-10-09 Weston Terence E Needle-less injector
SE9102652D0 (sv) * 1991-09-13 1991-09-13 Kabi Pharmacia Ab Injection needle arrangement
US5328483A (en) * 1992-02-27 1994-07-12 Jacoby Richard M Intradermal injection device with medication and needle guard
US5383851A (en) * 1992-07-24 1995-01-24 Bioject Inc. Needleless hypodermic injection device
US5569189A (en) * 1992-09-28 1996-10-29 Equidyne Systems, Inc. hypodermic jet injector
US5334144A (en) * 1992-10-30 1994-08-02 Becton, Dickinson And Company Single use disposable needleless injector
WO1995024176A1 (en) * 1994-03-07 1995-09-14 Bioject, Inc. Ampule filling device
US5466220A (en) * 1994-03-08 1995-11-14 Bioject, Inc. Drug vial mixing and transfer device
US5599302A (en) * 1995-01-09 1997-02-04 Medi-Ject Corporation Medical injection system and method, gas spring thereof and launching device using gas spring
US5893397A (en) * 1996-01-12 1999-04-13 Bioject Inc. Medication vial/syringe liquid-transfer apparatus
US5993412A (en) * 1997-05-19 1999-11-30 Bioject, Inc. Injection apparatus
CA2365575A1 (en) * 1999-03-31 2000-10-12 Otsuka Pharmaceutical Co., Ltd. Influenza virus hemagglutinin-binding peptides
WO2003074570A1 (fr) * 2002-03-04 2003-09-12 Japan Science And Technology Agency Nouvelles molecules de sialo-sucre ramifiees et agents antiviraux les utilisant
WO2004018698A2 (en) * 2002-08-20 2004-03-04 Genitrix, Llc Lectin compositions and methods for modulating an immune response to an antigen
US20050221337A1 (en) * 2003-10-02 2005-10-06 Massachusetts Institute Of Technology Microarrays and microspheres comprising oligosaccharides, complex carbohydrates or glycoproteins
EP2272950A3 (en) * 2004-11-11 2011-07-20 Abbott Biologicals B.V. Defective influenza virus particles
US7959929B2 (en) * 2005-04-21 2011-06-14 University Of Florida Research Foundation, Inc. Materials and methods for respiratory disease control in canines
US7871626B2 (en) * 2005-08-04 2011-01-18 St. Jude Children's Research Hospital Modified influenza virus for monitoring and improving vaccine efficiency
US20090099036A1 (en) * 2006-04-18 2009-04-16 The Regents Of The University Of Michigan Methods and compositions for screening glycan structures
US20080220988A1 (en) * 2007-03-07 2008-09-11 Ada Technologies, Inc. Preparing carbohydrate microarrays and conjugated nanoparticles
WO2011130575A1 (en) * 2010-04-16 2011-10-20 Massachusetts Institute Of Technology Modular glycan arrays

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005088310A2 (en) * 2004-03-05 2005-09-22 The Scripps Research Institute High throughput glycan microarrays

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013541528A (ja) * 2010-09-21 2013-11-14 マサチューセッツ インスティテュート オブ テクノロジー ヒト適応haポリペプチド、ワクチン、およびインフルエンザの処置
US9745352B2 (en) 2010-09-21 2017-08-29 Massachusetts Institute Of Technology Influenza treatment and/or characterization, human-adapted HA polypeptides; vaccines

Also Published As

Publication number Publication date
JP2010500880A (ja) 2010-01-14
EP2052340A2 (en) 2009-04-29
AU2007284496A1 (en) 2008-02-21
WO2008073161A2 (en) 2008-06-19
WO2008021415A9 (en) 2008-07-10
US20080241918A1 (en) 2008-10-02
CA2660128A1 (en) 2008-02-21
WO2008021415A3 (en) 2008-11-20
US20100125043A1 (en) 2010-05-20
WO2008021415A2 (en) 2008-02-21
WO2008073161A9 (en) 2008-07-31
CA2660038A1 (en) 2008-06-19
IL196738A0 (en) 2011-08-01
EP2049569A4 (en) 2010-11-24
WO2008073161A3 (en) 2009-05-22
US20100061990A1 (en) 2010-03-11
EP2052340A4 (en) 2010-11-17
AU2007332987A1 (en) 2008-06-19
KR20090050056A (ko) 2009-05-19
AU2007332987B2 (en) 2013-01-10
EP2049569A2 (en) 2009-04-22

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