JP2010500376A5 - - Google Patents

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Publication number
JP2010500376A5
JP2010500376A5 JP2009523988A JP2009523988A JP2010500376A5 JP 2010500376 A5 JP2010500376 A5 JP 2010500376A5 JP 2009523988 A JP2009523988 A JP 2009523988A JP 2009523988 A JP2009523988 A JP 2009523988A JP 2010500376 A5 JP2010500376 A5 JP 2010500376A5
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JP
Japan
Prior art keywords
alkyl
substituted
alkenyl
aryl
cycloalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2009523988A
Other languages
English (en)
Japanese (ja)
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JP2010500376A (ja
Filing date
Publication date
Priority claimed from US11/835,438 external-priority patent/US8034940B2/en
Application filed filed Critical
Publication of JP2010500376A publication Critical patent/JP2010500376A/ja
Publication of JP2010500376A5 publication Critical patent/JP2010500376A5/ja
Withdrawn legal-status Critical Current

Links

JP2009523988A 2006-08-09 2007-08-09 グルココルチコイド受容体、AP−1、および/またはNF−κB活性の調節剤、およびその使用 Withdrawn JP2010500376A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83649606P 2006-08-09 2006-08-09
US11/835,438 US8034940B2 (en) 2006-08-09 2007-08-08 Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
PCT/US2007/075543 WO2008021926A2 (en) 2006-08-09 2007-08-09 Modulators of glucocorticoid receptor, and/or ap-1, and/or nf-kb activity and use thereof

Publications (2)

Publication Number Publication Date
JP2010500376A JP2010500376A (ja) 2010-01-07
JP2010500376A5 true JP2010500376A5 (cg-RX-API-DMAC7.html) 2010-09-02

Family

ID=39052386

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009523988A Withdrawn JP2010500376A (ja) 2006-08-09 2007-08-09 グルココルチコイド受容体、AP−1、および/またはNF−κB活性の調節剤、およびその使用

Country Status (17)

Country Link
US (1) US8034940B2 (cg-RX-API-DMAC7.html)
EP (1) EP2049507A2 (cg-RX-API-DMAC7.html)
JP (1) JP2010500376A (cg-RX-API-DMAC7.html)
KR (1) KR20090038930A (cg-RX-API-DMAC7.html)
CN (1) CN101528718B (cg-RX-API-DMAC7.html)
AR (1) AR062312A1 (cg-RX-API-DMAC7.html)
AU (1) AU2007286221A1 (cg-RX-API-DMAC7.html)
BR (1) BRPI0716641A2 (cg-RX-API-DMAC7.html)
CA (1) CA2660318A1 (cg-RX-API-DMAC7.html)
CL (1) CL2007002330A1 (cg-RX-API-DMAC7.html)
EA (1) EA200900291A1 (cg-RX-API-DMAC7.html)
IL (1) IL196814A0 (cg-RX-API-DMAC7.html)
MX (1) MX2009001220A (cg-RX-API-DMAC7.html)
NO (1) NO20090564L (cg-RX-API-DMAC7.html)
PE (1) PE20081314A1 (cg-RX-API-DMAC7.html)
TW (1) TW200815454A (cg-RX-API-DMAC7.html)
WO (1) WO2008021926A2 (cg-RX-API-DMAC7.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11724982B2 (en) 2014-10-10 2023-08-15 The Research Foundation For The State University Of New York Trifluoromethoxylation of arenes via intramolecular trifluoromethoxy group migration

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2099767A1 (en) 2006-11-01 2009-09-16 Brystol-Myers Squibb Company Modulators of glucocorticoid receptor, ap-1, and/or nf- b activity and use thereof
US8067447B2 (en) 2006-11-01 2011-11-29 Bristol-Myers Squibb Company Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
ATE550337T1 (de) 2006-11-01 2012-04-15 Bristol Myers Squibb Co Modulatoren der glucocorticoidrezeptor-, ap-1- und/oder nf-kappa-b-aktivität und deren verwendung
US7968577B2 (en) 2006-11-01 2011-06-28 Bristol-Myers Squibb Company Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
WO2009100171A1 (en) * 2008-02-07 2009-08-13 Bristol-Myers Squibb Company Fused heteroaryl modulators of glucocorticoid receptor, ap-1, and/or nf-kb activity and use thereof
WO2009126691A1 (en) * 2008-04-09 2009-10-15 Infinity Pharmaceuticals, Inc Inhibitors of fatty acid amide hydrolase
WO2009152102A2 (en) * 2008-06-10 2009-12-17 The Regents Of The University Of California Pro-fluorescent probes
WO2009158380A1 (en) * 2008-06-24 2009-12-30 Bristol-Myers Squibb Company Cyclopentathiophene modulators of the glucocorticoid receptor, ap-1, and/or nf-kappa b activity and use thereof
EP2308880A4 (en) 2008-07-03 2012-06-06 Kyowa Hakko Kirin Co Ltd TETRACYCLIC CONNECTION
WO2011081173A1 (ja) * 2009-12-29 2011-07-07 協和発酵キリン株式会社 四環系化合物
WO2011087946A1 (en) * 2010-01-15 2011-07-21 Rigel Pharmaceuticals, Inc. Screening assay employing dex and gdf8
WO2015027021A1 (en) 2013-08-22 2015-02-26 Bristol-Myers Squibb Company Imide and acylurea derivatives as modulators of the glucocorticoid receptor
WO2015027015A1 (en) 2013-08-22 2015-02-26 Bristol-Myers Squibb Company Imidazole-derived modulators of the glucocorticoid receptor
EP3250197A1 (en) * 2015-01-27 2017-12-06 Indicator Systems International, Inc. Fluorescein polymer conjugates
WO2018030550A1 (en) 2016-08-09 2018-02-15 Takeda Pharmaceutical Company Limited Heterocyclic compounds with an ror(gamma)t modulating activity
EP3735410A4 (en) * 2017-10-19 2021-11-03 Tempest Therapeutics, Inc. PICOLINAMIDE COMPOUNDS
CN113862704B (zh) * 2021-11-15 2023-07-21 南昌航空大学 一种9-芳基呫吨类化合物的制备方法
AR127618A1 (es) 2021-11-29 2024-02-14 Bayer Ag Dihidropiranopiridinas sustituidas, sales o n-óxidos de las mismas y su uso como sustancias herbicidamente activas
CN117105821A (zh) * 2023-04-18 2023-11-24 重庆普佑制药有限公司 一种沙库比曲中间体的制备方法
CN117105820A (zh) * 2023-07-12 2023-11-24 上海阿拉丁生化科技股份有限公司 一种4-氟苯乙基异氰酸酯的制备方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8717446D0 (en) 1987-07-23 1987-08-26 Merck Sharp & Dohme Chemical compounds
US5053414A (en) 1988-04-08 1991-10-01 Ono Pharmaceutical Co., Ltd. Heterocyclic compounds
US5073566A (en) 1989-11-30 1991-12-17 Eli Lilly And Company Angiotensin ii antagonist 1,3-imidazoles and use thereas
US5563169A (en) * 1991-09-13 1996-10-08 Sankyo Company, Limited Tricyclic heterocyclic compound
US5453421A (en) * 1992-09-11 1995-09-26 E. R. Squibb & Sons, Inc. Aryl and heterocyclic substituted propenamide derivatives
TW306916B (cg-RX-API-DMAC7.html) 1994-09-13 1997-06-01 Ciba Geigy Ag
DE19610882A1 (de) * 1996-03-20 1997-09-25 Dresden Arzneimittel Neue 1,3,5-trisubstituierte Indazol-Derivate mit antiasthmatischer, antiallergischer, entzündungshemmender und immunmodulierender Wirkung, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
PL332593A1 (en) 1996-10-04 1999-09-27 Novo Nordisk As N-substituted azaheterocyclic compounds
CA2251580A1 (en) 1997-02-14 1998-08-20 Bayer Corporation Amides as npy5 receptor antagonists
CO4980885A1 (es) 1997-12-29 2000-11-27 Ortho Mcneil Pharm Inc Compuestos de trifenilpropanamida utiles en el tratamiento de inflamaciones y metodos para preparar dicho compuesto
CN1356977A (zh) 1999-05-17 2002-07-03 诺沃挪第克公司 胰高血糖素拮抗剂/反向激动剂
EP1463714A4 (en) 2001-12-10 2005-10-19 Amgen Inc VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS
WO2004056744A1 (en) 2002-12-23 2004-07-08 Janssen Pharmaceutica N.V. Adamantyl acetamides as hydroxysteroid dehydrogenase inhibitors
US7482344B2 (en) 2003-12-19 2009-01-27 Eli Lilly And Company Tricyclic steroid hormone nuclear receptor modulators
ES2308296T3 (es) 2003-12-19 2008-12-01 Eli Lilly And Company Modulares del receptor nuclear de hormonas esteroideas triciclicas.
TW200602314A (en) 2004-05-28 2006-01-16 Tanabe Seiyaku Co A novel pyrrolidine compound and a process for preparing the same
EP1828144A2 (en) 2004-11-12 2007-09-05 OSI Pharmaceuticals, Inc. Integrin antagonists useful as anticancer agents
US7317024B2 (en) 2005-01-13 2008-01-08 Bristol-Myers Squibb Co. Heterocyclic modulators of the glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
JP4943826B2 (ja) 2005-11-25 2012-05-30 田辺三菱製薬株式会社 医薬組成物
US7968577B2 (en) 2006-11-01 2011-06-28 Bristol-Myers Squibb Company Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
US8067447B2 (en) 2006-11-01 2011-11-29 Bristol-Myers Squibb Company Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
ATE550337T1 (de) 2006-11-01 2012-04-15 Bristol Myers Squibb Co Modulatoren der glucocorticoidrezeptor-, ap-1- und/oder nf-kappa-b-aktivität und deren verwendung
EP2099767A1 (en) 2006-11-01 2009-09-16 Brystol-Myers Squibb Company Modulators of glucocorticoid receptor, ap-1, and/or nf- b activity and use thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11724982B2 (en) 2014-10-10 2023-08-15 The Research Foundation For The State University Of New York Trifluoromethoxylation of arenes via intramolecular trifluoromethoxy group migration

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