JP2010155827A - スピロ環化合物 - Google Patents
スピロ環化合物 Download PDFInfo
- Publication number
- JP2010155827A JP2010155827A JP2009275269A JP2009275269A JP2010155827A JP 2010155827 A JP2010155827 A JP 2010155827A JP 2009275269 A JP2009275269 A JP 2009275269A JP 2009275269 A JP2009275269 A JP 2009275269A JP 2010155827 A JP2010155827 A JP 2010155827A
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- substituent
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- 0 Cc1cc(*C=C(*2)*(CC3)IC(CC=C)C3=O)c2cc1N Chemical compound Cc1cc(*C=C(*2)*(CC3)IC(CC=C)C3=O)c2cc1N 0.000 description 4
- NSCGIJSKXAMBGA-UHFFFAOYSA-N CC(C)(C)OC(N(CC(C12)OCCN1S(c(cc([s]1)Cl)c1Cl)(=O)=O)CC2F)=O Chemical compound CC(C)(C)OC(N(CC(C12)OCCN1S(c(cc([s]1)Cl)c1Cl)(=O)=O)CC2F)=O NSCGIJSKXAMBGA-UHFFFAOYSA-N 0.000 description 1
- NSCGIJSKXAMBGA-TTXORMCVSA-N CC(C)(C)OC(N(CC(C12)OCCN1S(c(cc([s]1)Cl)c1Cl)(=O)=O)C[C@H]2F)=O Chemical compound CC(C)(C)OC(N(CC(C12)OCCN1S(c(cc([s]1)Cl)c1Cl)(=O)=O)C[C@H]2F)=O NSCGIJSKXAMBGA-TTXORMCVSA-N 0.000 description 1
- VOMHDOIRSYDCPL-UHFFFAOYSA-N CC(CC(CC1C)=O)N1C(OCc1ccccc1)=O Chemical compound CC(CC(CC1C)=O)N1C(OCc1ccccc1)=O VOMHDOIRSYDCPL-UHFFFAOYSA-N 0.000 description 1
- FCEUYZXRMAFSCP-UHFFFAOYSA-N CC(CC1(CC2C)OCCN1S(c1ccccc1)(=O)=O)N2C(Nc1ccccc1)=O Chemical compound CC(CC1(CC2C)OCCN1S(c1ccccc1)(=O)=O)N2C(Nc1ccccc1)=O FCEUYZXRMAFSCP-UHFFFAOYSA-N 0.000 description 1
- FSJWOTVTPFEMGH-UHFFFAOYSA-O CC(CN(CC1NC=CC=C1)CC1)=C1N=CC([NH3+])Cl Chemical compound CC(CN(CC1NC=CC=C1)CC1)=C1N=CC([NH3+])Cl FSJWOTVTPFEMGH-UHFFFAOYSA-O 0.000 description 1
- AKITXFGTJVRYQY-ZYZRXSCRSA-N CC(CN(Cc1ccccc1)CC1)[C@@]11OCCN1S(c1ccccc1)(=O)=O Chemical compound CC(CN(Cc1ccccc1)CC1)[C@@]11OCCN1S(c1ccccc1)(=O)=O AKITXFGTJVRYQY-ZYZRXSCRSA-N 0.000 description 1
- MRAJIVXIAJURMU-IAXKEJLGSA-N CC(N1Cc2cnc(N(CC[C@@]34OCCN3S(c3ccccc3)(=O)=O)CC4F)nc2CC1)=O Chemical compound CC(N1Cc2cnc(N(CC[C@@]34OCCN3S(c3ccccc3)(=O)=O)CC4F)nc2CC1)=O MRAJIVXIAJURMU-IAXKEJLGSA-N 0.000 description 1
- YOZPNZYRSHNMLC-UHFFFAOYSA-N CCC(CC1)CCC1NC(N(CC1)CCC11OCCN1S(c1ccccc1)(=O)=O)=O Chemical compound CCC(CC1)CCC1NC(N(CC1)CCC11OCCN1S(c1ccccc1)(=O)=O)=O YOZPNZYRSHNMLC-UHFFFAOYSA-N 0.000 description 1
- JETYCIKQDZHNFU-CMDGGOBGSA-N CCCCC/C(/CC)=C/N Chemical compound CCCCC/C(/CC)=C/N JETYCIKQDZHNFU-CMDGGOBGSA-N 0.000 description 1
- UXXKVPIHADLOQU-YANBTOMASA-N CCc1c(CCCC2)c2nc(N(CC[C@@]23OCCN2S(c2ccccc2)(=O)=O)CC3F)n1 Chemical compound CCc1c(CCCC2)c2nc(N(CC[C@@]23OCCN2S(c2ccccc2)(=O)=O)CC3F)n1 UXXKVPIHADLOQU-YANBTOMASA-N 0.000 description 1
- IDDINPWKLIJCGO-DUSLRRAJSA-N CCc1ccnc(N(CCC23OCCN2S(c2ccccc2)(=O)=O)C[C@H]3F)n1 Chemical compound CCc1ccnc(N(CCC23OCCN2S(c2ccccc2)(=O)=O)C[C@H]3F)n1 IDDINPWKLIJCGO-DUSLRRAJSA-N 0.000 description 1
- UOZXAXJTEADTFQ-SSJUVGGLSA-N C[C@@](C(CN(C1)C(OCc2ccccc2)=O)/[O]=S(\c(cc2OC)ccc2F)/O)(C1F)NCCO Chemical compound C[C@@](C(CN(C1)C(OCc2ccccc2)=O)/[O]=S(\c(cc2OC)ccc2F)/O)(C1F)NCCO UOZXAXJTEADTFQ-SSJUVGGLSA-N 0.000 description 1
- BXBFLSLJQIMUJY-UNMCSNQZSA-N Cc(cc(cc1)S(N2[C@](CCN(C3)c(cnc4c5)nc4cc(F)c5F)([C@H]3F)OCC2)(=O)=O)c1F Chemical compound Cc(cc(cc1)S(N2[C@](CCN(C3)c(cnc4c5)nc4cc(F)c5F)([C@H]3F)OCC2)(=O)=O)c1F BXBFLSLJQIMUJY-UNMCSNQZSA-N 0.000 description 1
- JWRQUUKWDDPKIA-UHFFFAOYSA-N Cc(cc1S(N(CCO)C(CC2)CCN2c2cnc(cc(c(F)c3)F)c3n2)(=O)=O)ccc1F Chemical compound Cc(cc1S(N(CCO)C(CC2)CCN2c2cnc(cc(c(F)c3)F)c3n2)(=O)=O)ccc1F JWRQUUKWDDPKIA-UHFFFAOYSA-N 0.000 description 1
- FJQTUOANRQAGTR-DIMJTDRSSA-N Cc(cc1S(N(CCO)C(CCN(C2)c(cnc3c4)nc3cc(F)c4F)[C@H]2F)(=O)=O)ccc1F Chemical compound Cc(cc1S(N(CCO)C(CCN(C2)c(cnc3c4)nc3cc(F)c4F)[C@H]2F)(=O)=O)ccc1F FJQTUOANRQAGTR-DIMJTDRSSA-N 0.000 description 1
- BKEPFXLMCHKRBM-UHFFFAOYSA-N Cc(cccc1)c1S(N1C(CC2)(CCN2C(Nc2ccccc2)=O)OCC1)(=O)=O Chemical compound Cc(cccc1)c1S(N1C(CC2)(CCN2C(Nc2ccccc2)=O)OCC1)(=O)=O BKEPFXLMCHKRBM-UHFFFAOYSA-N 0.000 description 1
- SITPCQODJWIJGP-UHFFFAOYSA-N Cc(cccc1)c1S(N1C(CC2)(CCN2c2nc(cccc3)c3nc2)SCC1)(=O)=O Chemical compound Cc(cccc1)c1S(N1C(CC2)(CCN2c2nc(cccc3)c3nc2)SCC1)(=O)=O SITPCQODJWIJGP-UHFFFAOYSA-N 0.000 description 1
- YXFVVABEGXRONW-UHFFFAOYSA-N Cc1ccccc1 Chemical compound Cc1ccccc1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 1
- VZTVLKXZCYKKID-UHFFFAOYSA-N O=C(Cc1ccccc1)N(CC1)CCC11OCCN1S(c1ccccc1)(=O)=O Chemical compound O=C(Cc1ccccc1)N(CC1)CCC11OCCN1S(c1ccccc1)(=O)=O VZTVLKXZCYKKID-UHFFFAOYSA-N 0.000 description 1
- FAOFEHJJQISURS-UHFFFAOYSA-N O=C(NC1CCCC1)N(CC1)CCC11OCCN1S(c1ccccc1)(=O)=O Chemical compound O=C(NC1CCCC1)N(CC1)CCC11OCCN1S(c1ccccc1)(=O)=O FAOFEHJJQISURS-UHFFFAOYSA-N 0.000 description 1
- RAYGNEKKNRENCU-UHFFFAOYSA-N O=C(Nc1ccc(C(F)(F)F)cc1Cl)N(CC1)CCC11OCCN1S(c1ccccc1)(=O)=O Chemical compound O=C(Nc1ccc(C(F)(F)F)cc1Cl)N(CC1)CCC11OCCN1S(c1ccccc1)(=O)=O RAYGNEKKNRENCU-UHFFFAOYSA-N 0.000 description 1
- MXCWAKUAVYWIHQ-UHFFFAOYSA-N O=C(Nc1cccc(F)c1)N(CC(C12OCCN1)/[O]=S/c(cc1F)ccc1F)CC2(F)F Chemical compound O=C(Nc1cccc(F)c1)N(CC(C12OCCN1)/[O]=S/c(cc1F)ccc1F)CC2(F)F MXCWAKUAVYWIHQ-UHFFFAOYSA-N 0.000 description 1
- SBHCNTGXHMGEON-UHFFFAOYSA-N O=C(Nc1ccccc1)N(CC1)CCC11OCCN1S(c1cc(F)ccc1)(=O)=O Chemical compound O=C(Nc1ccccc1)N(CC1)CCC11OCCN1S(c1cc(F)ccc1)(=O)=O SBHCNTGXHMGEON-UHFFFAOYSA-N 0.000 description 1
- BQMMNWAJPLVYIB-UHFFFAOYSA-N O=C(Nc1ccccc1)N(CCC12OCCN1S(c1ccccc1)=O)CC2(F)F Chemical compound O=C(Nc1ccccc1)N(CCC12OCCN1S(c1ccccc1)=O)CC2(F)F BQMMNWAJPLVYIB-UHFFFAOYSA-N 0.000 description 1
- JSJWQXSSQJPVPR-IJHRGXPZSA-N O=C(Nc1ccccc1)N(CC[C@@]12OCCN1S(c1ccccc1)(=O)=O)CC2F Chemical compound O=C(Nc1ccccc1)N(CC[C@@]12OCCN1S(c1ccccc1)(=O)=O)CC2F JSJWQXSSQJPVPR-IJHRGXPZSA-N 0.000 description 1
- ZBLMHLVOMDKBRR-FPOVZHCZSA-N O=S(c(c(F)c1)cc(F)c1F)(N1[C@](CCN(C2)c(cnc3c4)nc3cc(F)c4F)([C@H]2F)OCC1)=O Chemical compound O=S(c(c(F)c1)cc(F)c1F)(N1[C@](CCN(C2)c(cnc3c4)nc3cc(F)c4F)([C@H]2F)OCC1)=O ZBLMHLVOMDKBRR-FPOVZHCZSA-N 0.000 description 1
- CDGUZOKYBQJVAR-UHFFFAOYSA-N O=S(c(cc1)ccc1Cl)(N1C(CC2)(CCN2c2nc(cccc3)c3nc2)SCC1)=O Chemical compound O=S(c(cc1)ccc1Cl)(N1C(CC2)(CCN2c2nc(cccc3)c3nc2)SCC1)=O CDGUZOKYBQJVAR-UHFFFAOYSA-N 0.000 description 1
- LICVYCVQJJJCDJ-UHFFFAOYSA-N O=S(c(ccc(F)c1F)c1F)(N1C(CC2)(CCN2c2nc3ccccc3nc2)SCC1)=O Chemical compound O=S(c(ccc(F)c1F)c1F)(N1C(CC2)(CCN2c2nc3ccccc3nc2)SCC1)=O LICVYCVQJJJCDJ-UHFFFAOYSA-N 0.000 description 1
- DRHAEROEKASDQT-UGKGYDQZSA-N O=S(c1cc(OC(F)F)ccc1)([IH]N1[C@](CCN(C2)c(cnc3c4)nc3cc(F)c4F)([C@H]2F)OCC1)=O Chemical compound O=S(c1cc(OC(F)F)ccc1)([IH]N1[C@](CCN(C2)c(cnc3c4)nc3cc(F)c4F)([C@H]2F)OCC1)=O DRHAEROEKASDQT-UGKGYDQZSA-N 0.000 description 1
- PJBSTPIISJJSPR-UHFFFAOYSA-N O=S(c1ccc[s]1)(N1C(CC2)(CCN2c2cnc(cccc3)c3n2)SCC1)=O Chemical compound O=S(c1ccc[s]1)(N1C(CC2)(CCN2c2cnc(cccc3)c3n2)SCC1)=O PJBSTPIISJJSPR-UHFFFAOYSA-N 0.000 description 1
- PQQIFARENPJHRQ-UHFFFAOYSA-N O=S(c1ccccc1)(N1C(CC2)(CCN2c2nc(cccc3)c3nc2)SCC1)=O Chemical compound O=S(c1ccccc1)(N1C(CC2)(CCN2c2nc(cccc3)c3nc2)SCC1)=O PQQIFARENPJHRQ-UHFFFAOYSA-N 0.000 description 1
- DTGVWLBWQZFZJN-QWAKEFERSA-N O=S(c1ccccc1)(N1[C@](CCN(C2)c3nc(cc(c(F)c4)F)c4nc3)(C2F)OCC1)=O Chemical compound O=S(c1ccccc1)(N1[C@](CCN(C2)c3nc(cc(c(F)c4)F)c4nc3)(C2F)OCC1)=O DTGVWLBWQZFZJN-QWAKEFERSA-N 0.000 description 1
- COUDHHUGLPEWGC-GZGBFMKVSA-N O=S(c1ccccc1)(N1[C@](C[C@H]2CC3)(CC3N2c2nc3ccccc3nc2)OCC1)=O Chemical compound O=S(c1ccccc1)(N1[C@](C[C@H]2CC3)(CC3N2c2nc3ccccc3nc2)OCC1)=O COUDHHUGLPEWGC-GZGBFMKVSA-N 0.000 description 1
- QZLMPXVXUNGXQJ-QBZAPZKZSA-N OC(Nc(cc1)ccc1F)N(CCC1[C@H]2OCCN2S(c(cc2)ccc2F)=O)CC1F Chemical compound OC(Nc(cc1)ccc1F)N(CCC1[C@H]2OCCN2S(c(cc2)ccc2F)=O)CC1F QZLMPXVXUNGXQJ-QBZAPZKZSA-N 0.000 description 1
- SFYPJTSDRZRIBY-UHFFFAOYSA-N OCCN(C(CC1)CCN1c1cnc(cc(c(F)c2)F)c2n1)S(c(cc1)cc(Cl)c1F)(=O)=O Chemical compound OCCN(C(CC1)CCN1c1cnc(cc(c(F)c2)F)c2n1)S(c(cc1)cc(Cl)c1F)(=O)=O SFYPJTSDRZRIBY-UHFFFAOYSA-N 0.000 description 1
- DHPLIDZEOFEELN-UHFFFAOYSA-N OCCN(C(CC1)CCN1c1cnc(cc(c(F)c2)F)c2n1)S(c(cc1)cc(F)c1F)(=O)=O Chemical compound OCCN(C(CC1)CCN1c1cnc(cc(c(F)c2)F)c2n1)S(c(cc1)cc(F)c1F)(=O)=O DHPLIDZEOFEELN-UHFFFAOYSA-N 0.000 description 1
- QZNVRMSYARKZNZ-UHFFFAOYSA-N OCCN(C(CC1)CCN1c1cnc(cc(c(F)c2)F)c2n1)S(c1c(cccc2)c2ccc1)(=O)=O Chemical compound OCCN(C(CC1)CCN1c1cnc(cc(c(F)c2)F)c2n1)S(c1c(cccc2)c2ccc1)(=O)=O QZNVRMSYARKZNZ-UHFFFAOYSA-N 0.000 description 1
- COMQNQAJQFXICN-UHFFFAOYSA-N OCCN(C(CC1)CCN1c1nc(cc(c(F)c2)F)c2nc1)[IH]S(c(cc1)cc2c1OCC2)(=O)=O Chemical compound OCCN(C(CC1)CCN1c1nc(cc(c(F)c2)F)c2nc1)[IH]S(c(cc1)cc2c1OCC2)(=O)=O COMQNQAJQFXICN-UHFFFAOYSA-N 0.000 description 1
- WBXFRHOLJLAHAR-UHFFFAOYSA-N OCCN(C(CC1)CCN1c1nc(cc(c(F)c2)F)c2nc1)[IH]S(c(cc1)ccc1-[n]1nccc1)(=O)=O Chemical compound OCCN(C(CC1)CCN1c1nc(cc(c(F)c2)F)c2nc1)[IH]S(c(cc1)ccc1-[n]1nccc1)(=O)=O WBXFRHOLJLAHAR-UHFFFAOYSA-N 0.000 description 1
- VTHCUUYJLUCOMK-OZBJMMHXSA-N OCCN([C@@H](CCN(C1)c2nc(cc(c(F)c3)F)c3nc2)C1F)S(c1ccccc1)(=O)=O Chemical compound OCCN([C@@H](CCN(C1)c2nc(cc(c(F)c3)F)c3nc2)C1F)S(c1ccccc1)(=O)=O VTHCUUYJLUCOMK-OZBJMMHXSA-N 0.000 description 1
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- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2009275269A JP2010155827A (ja) | 2008-12-04 | 2009-12-03 | スピロ環化合物 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2008310301 | 2008-12-04 | ||
JP2009275269A JP2010155827A (ja) | 2008-12-04 | 2009-12-03 | スピロ環化合物 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2010155827A true JP2010155827A (ja) | 2010-07-15 |
JP2010155827A5 JP2010155827A5 (fi) | 2013-01-17 |
Family
ID=42574021
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2009275269A Ceased JP2010155827A (ja) | 2008-12-04 | 2009-12-03 | スピロ環化合物 |
Country Status (1)
Country | Link |
---|---|
JP (1) | JP2010155827A (fi) |
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2012515763A (ja) * | 2009-01-26 | 2012-07-12 | イスラエル インスティトゥート フォー バイオロジカル リサーチ | 複素二環スピロ化合物 |
WO2015012210A1 (ja) | 2013-07-23 | 2015-01-29 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ヘテロ縮合環化合物 |
CN105859726A (zh) * | 2016-05-18 | 2016-08-17 | 南京富润凯德生物医药有限公司 | 一种嘧啶并环中选择性脱卤素的方法 |
US9440982B2 (en) | 2012-02-07 | 2016-09-13 | Eolas Therapeutics, Inc. | Substituted prolines/piperidines as orexin receptor antagonists |
US9499517B2 (en) | 2012-02-07 | 2016-11-22 | Eolas Therapeutics, Inc. | Substituted prolines / piperidines as orexin receptor antagonists |
JP2017506635A (ja) * | 2014-02-20 | 2017-03-09 | 武田薬品工業株式会社 | オレキシン受容体アンタゴニストとしての1,2−置換シクロペンタン |
US10221170B2 (en) | 2014-08-13 | 2019-03-05 | Eolas Therapeutics, Inc. | Difluoropyrrolidines as orexin receptor modulators |
US10894789B2 (en) | 2016-02-12 | 2021-01-19 | Astrazeneca Ab | Halo-substituted piperidines as orexin receptor modulators |
JP2021513549A (ja) * | 2018-02-13 | 2021-05-27 | 上海 インスティテュート オブ オーガニック ケミストリー、チャイニーズ アカデミー オブ サイエンシーズShanghai Institute Of Organic Chemistry, Chinese Academy Of Sciences | インドール−2、3−ジオキシゲナーゼ阻害剤としてのスピロ化合物 |
CN115003655A (zh) * | 2019-11-27 | 2022-09-02 | 住友制药株式会社 | 环烷基脲衍生物 |
WO2022250108A1 (ja) * | 2021-05-26 | 2022-12-01 | 住友ファーマ株式会社 | フェニルウレア誘導体 |
EP4269394A4 (en) * | 2021-01-29 | 2024-07-24 | Korea Res Inst Chemical Tech | BENZOTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, THEIR PREPARATION PROCESS AND PHARMACEUTICAL COMPOSITION INCLUDING THEM AS ACTIVE INGREDIENT |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3577425A (en) * | 1967-12-11 | 1971-05-04 | Yoshitomi Pharmaceutical | 8-(1,4-benzodioxan-2-ylmethyl)-3-oxo-1-thia-4,8-diazaspiro(4,5)decanes |
WO2007025069A2 (en) * | 2005-08-26 | 2007-03-01 | Merck & Co., Inc. | Diazaspirodecane orexin receptor antagonists |
-
2009
- 2009-12-03 JP JP2009275269A patent/JP2010155827A/ja not_active Ceased
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3577425A (en) * | 1967-12-11 | 1971-05-04 | Yoshitomi Pharmaceutical | 8-(1,4-benzodioxan-2-ylmethyl)-3-oxo-1-thia-4,8-diazaspiro(4,5)decanes |
WO2007025069A2 (en) * | 2005-08-26 | 2007-03-01 | Merck & Co., Inc. | Diazaspirodecane orexin receptor antagonists |
Cited By (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2012515763A (ja) * | 2009-01-26 | 2012-07-12 | イスラエル インスティトゥート フォー バイオロジカル リサーチ | 複素二環スピロ化合物 |
US9499517B2 (en) | 2012-02-07 | 2016-11-22 | Eolas Therapeutics, Inc. | Substituted prolines / piperidines as orexin receptor antagonists |
US9896452B2 (en) | 2012-02-07 | 2018-02-20 | Eolas Therapeutics, Inc. | Substituted prolines/piperidines as orexin receptor antagonists |
US9440982B2 (en) | 2012-02-07 | 2016-09-13 | Eolas Therapeutics, Inc. | Substituted prolines/piperidines as orexin receptor antagonists |
US9975910B2 (en) | 2013-07-23 | 2018-05-22 | Eisai R&D Management Co., Ltd. | Hetero-fused cyclic compound |
JPWO2015012210A1 (ja) * | 2013-07-23 | 2017-03-02 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ヘテロ縮合環化合物 |
WO2015012210A1 (ja) | 2013-07-23 | 2015-01-29 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ヘテロ縮合環化合物 |
JP2017506635A (ja) * | 2014-02-20 | 2017-03-09 | 武田薬品工業株式会社 | オレキシン受容体アンタゴニストとしての1,2−置換シクロペンタン |
US10221170B2 (en) | 2014-08-13 | 2019-03-05 | Eolas Therapeutics, Inc. | Difluoropyrrolidines as orexin receptor modulators |
US10894789B2 (en) | 2016-02-12 | 2021-01-19 | Astrazeneca Ab | Halo-substituted piperidines as orexin receptor modulators |
CN105859726A (zh) * | 2016-05-18 | 2016-08-17 | 南京富润凯德生物医药有限公司 | 一种嘧啶并环中选择性脱卤素的方法 |
JP2021513549A (ja) * | 2018-02-13 | 2021-05-27 | 上海 インスティテュート オブ オーガニック ケミストリー、チャイニーズ アカデミー オブ サイエンシーズShanghai Institute Of Organic Chemistry, Chinese Academy Of Sciences | インドール−2、3−ジオキシゲナーゼ阻害剤としてのスピロ化合物 |
CN115003655A (zh) * | 2019-11-27 | 2022-09-02 | 住友制药株式会社 | 环烷基脲衍生物 |
EP4067344A4 (en) * | 2019-11-27 | 2023-12-20 | Sumitomo Pharma Co., Ltd. | CYCLOALKYL UREA DERIVATIVE |
EP4269394A4 (en) * | 2021-01-29 | 2024-07-24 | Korea Res Inst Chemical Tech | BENZOTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, THEIR PREPARATION PROCESS AND PHARMACEUTICAL COMPOSITION INCLUDING THEM AS ACTIVE INGREDIENT |
WO2022250108A1 (ja) * | 2021-05-26 | 2022-12-01 | 住友ファーマ株式会社 | フェニルウレア誘導体 |
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