JP2010155827A

JP2010155827A - スピロ環化合物

スピロ環化合物 Download PDF

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Publication number: JP2010155827A
Authority: JP; Japan
Prior art keywords: group; optionally substituted; compound; mmol; substituent
Prior art date: 2008-12-04
Legal status : Ceased

Application number

JP2009275269A

Other languages

English (en)

Japanese (ja)

Other versions

JP2010155827A5 (enrdf_load_stackoverflow

Inventor

Tatsuhiko Fujimoto

辰彦藤本

Norihide Toomata

慶英遠又

Current Assignee

Takeda Pharmaceutical Co Ltd

Original Assignee

Takeda Chemical Industries Ltd

Priority date

2008-12-04

Filing date

2009-12-03

Publication date

2010-07-15

2009-12-03 Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd

2009-12-03 Priority to JP2009275269A priority Critical patent/JP2010155827A/ja

2010-07-15 Publication of JP2010155827A publication Critical patent/JP2010155827A/ja

2013-01-17 Publication of JP2010155827A5 publication Critical patent/JP2010155827A5/ja

Status Ceased legal-status Critical Current

Links

150000001875 compounds Chemical class 0.000 title claims abstract description 316
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208000020016 psychiatric disease Diseases 0.000 claims abstract description 13
229910052717 sulfur Inorganic materials 0.000 claims abstract description 12
229910052760 oxygen Inorganic materials 0.000 claims abstract description 9
229940124597 therapeutic agent Drugs 0.000 claims abstract description 8
230000003449 preventive effect Effects 0.000 claims abstract description 6
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125000001424 substituent group Chemical group 0.000 claims description 236
125000005843 halogen group Chemical group 0.000 claims description 221
125000004169 (C1-C6) alkyl group Chemical group 0.000 claims description 201
125000000623 heterocyclic group Chemical group 0.000 claims description 98
125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 59
238000000034 method Methods 0.000 claims description 47
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241000124008 Mammalia Species 0.000 claims description 10
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239000000556 agonist Substances 0.000 description 27
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