JP2010011901A - Mixed injection member - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a mixed injection member to be connected to a blood circuit and capable of sufficiently suppressing disadvantage that a blood clot is formed in its inside. <P>SOLUTION: This mixed injection member 15 is provided with a communication passageway 20 communicated with the upstream section and the downstream section of the blood circuit 1 and allowing the passing of blood, and an insertion section 22 at the inner wall 20a of the communication passageway 20. An insertion tube is inserted into the insertion section 22 to communicate the communication passageway 20 with an insertion tube. The whole circumference of the inner wall 20a of the communication passageway 20 is formed flush with the inner circumferential face of the blood circuit 1 into a continuous face with no level difference. <P>COPYRIGHT: (C)2010,JPO&INPIT

Description

  The present invention relates to a co-infusion member provided with an insertion part for connecting an upstream part and a downstream part of a blood circuit and injecting a drug solution into the blood circuit or collecting blood in the blood circuit.

  A blood circuit used for artificial dialysis treatment or the like includes a mixed injection member (so-called access port) that connects an upstream portion and a downstream portion of the blood circuit in the middle of the blood circuit, and a rubber stopper is provided in a part of the mixed injection member. A penetration part (insertion part) made of the body is provided. Then, a puncture tube (insertion tube) of a syringe is inserted into the piercing portion to communicate the syringe and the blood circuit, and in this communication state, the drug solution in the syringe is injected from the puncture tube into the blood circuit, or the blood circuit It is configured to collect blood inside. Furthermore, a space portion having a cross-sectional area wider than the cross-sectional area of the flow path in the blood circuit is formed by denting the partition wall toward the perforation portion side in the portion of the mixed injection member facing the penetration portion. The puncture tube is deeply inserted into the space and is configured to communicate with the blood circuit in a stable state.

  However, blood is likely to stay or air remains in the vicinity of the piercing portion, that is, in the portion formed to be recessed toward the piercing portion, and as a result, blood clots and clots are formed. Easy to form. The thrombus may drop from the mixed injection member and block the blood circuit in the middle (specifically, a mesh (filter) in the drip chamber). In addition, when blood is to be collected from the puncture tube, there is a risk that a blood clot may clog the puncture tube, making it difficult to collect blood.

Therefore, the bottom portion of the space portion is made higher than the bottom portion of the flow path of the blood circuit (see Patent Document 1), or the protruding portion from the position facing the piercing portion of the partition wall of the space portion toward the piercing portion. (See Patent Document 2), a mixed injection member that attempts to prevent thrombus formation has been proposed. The mixed injection member having a lower bottom of the space portion avoids the formation of a depression in which blood or air can stay, and eliminates the inconvenience of generating a thrombus. In addition, the mixed injection member provided with the bulging portion causes blood to flow also in the vicinity of the piercing portion by colliding the blood flow with the bulging portion, and the inconvenience that blood stays in the vicinity of the piercing portion, and thus thrombus It tries to eliminate the inconvenience that is formed.
Japanese Patent No. 3747912 JP 2006-129984 A

  However, the devices described in each of the above-mentioned patent documents form a step in the connection portion between the space portion and the flow path of the blood circuit or in the space portion, and blood or air may stay in the step portion. For this reason, the formation of thrombus cannot be sufficiently suppressed, leaving room for improvement.

  The present invention has been made in view of the above-described circumstances, and an object thereof is to provide a co-infusion member that can sufficiently suppress the inconvenience that a thrombus is formed inside.

The present invention has been proposed in order to achieve the above-mentioned object, and the device according to claim 1 includes a communication passage that allows blood to pass through the upstream portion and the downstream portion of the blood circuit. A mixed injection member that is provided with an insertion portion on the inner wall of the communication passage, allows the insertion passage to pass through the insertion tube, and allows the communication passage and the insertion tube to communicate with each other.
The co-infusion member is characterized in that the entire inner wall of the communication passage is formed on a continuous surface having no step with the inner peripheral surface of the blood circuit.

  According to a second aspect of the present invention, the exposed surface exposed to the communication path in the insertion portion is formed so as to be aligned on a continuous surface having no step with the inner peripheral surface of the blood circuit. It is a mixed injection member as described in above.

  According to a third aspect of the present invention, in the mixed injection member according to the first or second aspect, the insertion portion includes a plug formed of an elastic member.

According to the present invention, the following excellent effects can be obtained.
That is, a communication passage that is communicated with the upstream portion and the downstream portion of the blood circuit and through which blood can pass is provided. The entire inner wall of the communication passage is formed on a continuous surface that has no step with the inner peripheral surface of the blood circuit, so blood and physiological saline can be introduced into the communication passage. It can be guided smoothly and no stagnation occurs in the blood or saline flow. Therefore, it is possible to prevent the retention of blood and the remaining of air in the mixed injection member, and it is possible to sufficiently suppress the disadvantage that a thrombus is formed due to the influence of the staying blood and the remaining air.

  In addition, the exposed surface exposed to the communication path in the insertion portion is formed so as to be aligned with the inner peripheral surface of the blood circuit on a continuous surface without a step, so that blood retention and air are formed on the exposed surface and the periphery of the exposed surface. Can be prevented, and the inconvenience that thrombus is formed by the influence of the staying blood and the remaining air can be more reliably suppressed.

DESCRIPTION OF EXEMPLARY EMBODIMENTS Hereinafter, the best embodiment of the invention will be described with reference to the drawings.
FIG. 1 is a schematic diagram of a blood circuit 1. As shown in FIG. 1, a blood circuit 1 used for blood purification therapy by extracorporeal circulation such as an artificial dialysis treatment is in the middle of a first path A composed of a tube 4 connecting a puncture needle 2 and a puncture needle 3. A flexible tube 6 with which the blood pump 5 abuts, drip chambers 7 and 8 and a blood purifier 9 are disposed, and an infusion chamber 11 is disposed in the middle of the second path B branched by the T tube 10. Has been. In addition, the tip of the second path B is connected to the infusion container 12 and supplies physiological saline to the first path A via the second path B at the time of priming. In the circulation, an infusion solution or blood transfusion can be performed. In the blood circuit 1, the tube 4 and the drip chambers 7 and 8 constituting most of the first path A function as an internal see-through unit that can see through the internal blood from the outside.

  A mixed injection member 15 is provided in the middle part of the blood circuit 1, specifically, in the middle part of the tube 4. As shown in FIG. 2, the mixed injection member 15 includes a long housing 16. One end of the housing 16 (the left end in FIGS. 2A to 2D) has an upstream connection with a circular cross section. A space portion 17 is formed, and the upstream connection space portion 17 can be fitted with an upstream portion of the blood circuit 1, specifically, an end portion of the tube 4 positioned on the upstream side of the co-infusion member 15. Further, at the other end of the housing 16 (the right end in FIGS. 2A to 2D), the downstream connection space 18 having a circular cross section is connected to the central axis of the upstream connection space 17 and the downstream connection space 18. And the end of the tube 4 located downstream of the co-infusion member 15 is fitted into the downstream connection space 18 in detail. It is possible. As shown in FIG. 2D, a communication passage 20 having a circular cross section extending along the longitudinal direction of the housing 16 is formed between the upstream connection space portion 17 and the downstream connection space portion 18. The communication path 20 communicates with the upstream connection space 17 and the downstream connection space 18. Therefore, the mixed injection member 15 communicates the communication path 20 with the upstream portion and the downstream portion of the blood circuit 1 so that blood can pass through the communication path 20. The housing 16 is made of a plastic material such as polycarbonate or hard vinyl chloride.

  In addition, the diameter of the communication path 20 gradually decreases as it goes from both ends toward the center, and the inner wall 20a of the communication path 20 is formed with a cylindrical curved surface having no gentle steps. Then, both ends of the communication path 20 are set to have the same inner diameter as the tube 4 (blood circuit 1), and the central axis of the communication path 20 is on an extension line of the central axis of the tube 4 (or the upstream connection space portion 17 and the downstream connection space). The entire circumference of the inner wall 20a of the communication passage 20 formed by a cylindrical curved surface is set on a continuous surface having no step with the inner circumferential surface of the tube 4 (in other words, on the same curved surface). ).

  Furthermore, a part of the inner wall 20a of the communication path 20 is provided with an insertion portion 22 through which an insertion tube (not shown) such as an injection tube for injecting a drug or a blood collection tube for blood collection can be inserted and removed, It is configured such that a drug solution or the like can be injected into the blood circuit 1 (specifically, blood flowing in the blood circuit 1) or blood can be collected from the blood circuit 1 via the insertion portion 22. Specifically, a portion of the inner wall 20a of the communication passage 20 that is different from the portion to which the upstream connection space portion 17 or the downstream connection space portion 18 is connected is opened, and the insertion portion 22 is provided at the opening. As shown in FIGS. 2 (d) and 2 (e), the insertion portion 22 is provided with a plug (so-called rubber button) 24 on the side of the inner wall 20 a to close the opening in a liquid-tight state. The exposed surface 24a exposed to the communication path 20 is formed so as to be aligned on the inner peripheral surface of the tube 4 (blood circuit 1) and the inner wall 20a of the communication path 20 on a continuous surface (in other words, on the same curved surface). However, the plug body 24 is avoided from being disposed in a state of protruding or recessed from the inner wall 20a of the communication path 20. The plug 24 is made of an elastic material such as silicone rubber or isoprene rubber.

  Further, an edge located outside the plug body 24 (on the opposite side of the communication path 20 across the plug body 24) is covered with a cover 25, and the cover 25 is fixed to the housing 16 so that the plug body 24 falls off. In the central portion of the cover 25, a through-hole 25a is opened with a size that allows the insertion tube to sufficiently pass therethrough, and the plug 24 is opened outwardly (in other words, the communication passage 20 from the through-hole 25a). It is exposed in the opposite direction. Furthermore, a slit (insertion port) 26 is formed in a portion of the plug body 24 extending from the exposed surface 24 a to the through hole 25 a, and the slit 26 is elastically restored to the plug body 24 in a normal state where the insertion tube is not inserted into the slit 26. When the insertion tube is pushed into the slit 26 against the elastic restoring force of the plug 24, the slit 26 is opened and the insertion tube is passed, and the edge of the slit 26 and the insertion tube are closed. It is comprised so that it may closely_contact | adhere with an outer peripheral surface in a liquid-tight state. If the open end of the insertion tube faces the communication passage 20, the insertion tube can be connected to the communication passage 20, and thus the insertion tube can be connected to the inside of the blood circuit 1. The cover 25 is made of a plastic material such as polypropylene, polycarbonate, or hard vinyl chloride.

  When the mixed injection member 15 having such a configuration is provided in the blood circuit 1 and a priming operation is performed by flowing physiological saline from the upstream side of the blood circuit 1, the physiological saline is communicated from the tube 4 to the communication path 20 of the mixed injection member 15. Flow into. At this time, since the entire circumference of the inner wall 20a of the communication path 20 is formed on a continuous surface having no step with the inner peripheral surface of the tube 4 (blood circuit 1), the physiological saline is communicated from the tube 4 to the communication path. 20 can be smoothly guided into the saline solution, and no stagnation occurs in the physiological saline flow. Therefore, it is possible to sufficiently suppress the inconvenience that air in the co-infusion member 15 is washed away with physiological saline and the air remains, and that thrombus is formed due to the residual air during dialysis treatment. Moreover, since the exposed surface 24a of the insertion part 22 (plug 24) is also formed on the continuous surface without a step with the inner peripheral surface of the blood circuit 1, the exposed surface 24a and the peripheral edge of the exposed surface 24a Therefore, it is possible to prevent the remaining of air from occurring, and it is possible to further suppress the disadvantage that a thrombus is formed due to the influence of the remaining air. The staff who performs dialysis treatment does not need to frequently check whether or not air remains, or lightly tap the mixed injection member 15 to eliminate the remaining air. It is easy to reduce the burden. Furthermore, dialysis preparation can be performed without applying an impact to the mixed injection member 15, and the inconvenience that the mixed injection member 15 is damaged and consequently the start of the dialysis treatment can be suppressed.

  When the dialysis treatment is started and the blood is allowed to flow down from the upstream side of the blood circuit 1, the blood flows from the tube 4 into the communication path 20 of the mixed injection member 15. At this time, the entire circumference of the inner wall 20a of the communication path 20 is formed so as to be aligned with the inner peripheral surface of the tube 4 (blood circuit 1) on a continuous surface without a step, so that blood can be passed from the tube 4 to It can be smoothly guided to the bloodstream, and no stagnation occurs in the blood flow. Therefore, it is possible to prevent blood from staying in the mixed injection member 15, and to sufficiently suppress the inconvenience that a thrombus is formed by the staying blood. Moreover, since the exposed surface 24a of the insertion part 22 (plug 24) is also formed on the continuous surface without a step with the inner peripheral surface of the blood circuit 1, the exposed surface 24a and the peripheral edge of the exposed surface 24a Therefore, it is possible to prevent blood from staying, and it is possible to more reliably suppress the inconvenience that thrombus is formed by the staying blood. In addition, it is possible to eliminate the possibility of clogging the thrombus in the mesh in the drip chamber 8 arranged on the downstream side of the mixed injection member 15, and stable dialysis treatment can be performed. Moreover, at the time of blood collection, there is no possibility that the insertion tube communicated with the communication path 20 via the insertion portion 22 is clogged with thrombus, and blood collection can be performed smoothly. In addition, it is possible to suppress the inconvenience that blood clots are mixed with the collected blood and to improve the reliability of the test data of the collected blood.

  In addition, thrombus generation can be suppressed by aligning the entire circumference of the inner wall 20a of the communication passage 20, the exposed surface 24a of the insertion portion 22 (plug 24), and the inner circumferential surface of the blood circuit 1 on a continuous surface having no steps. it can. Therefore, it is possible to realize the mixed injection member 15 in which thrombus is unlikely to occur without adding special parts to the configuration of the conventional mixed injection member 15, and the manufacturing cost of the mixed injection member 15 in which thrombus is unlikely to be generated is increased. The complexity of the process can be avoided.

  Further, both ends of the communication path 20 are aligned with the inner diameter of the tube 4, and the diameter of the communication path 20 is gradually reduced from both ends toward the central part, and the central part of the communication path 20 is aligned with the curved surface of the exposed surface 24 a of the plug body 24. Therefore, even if the setting (size) of the opening diameter of the end portion of the communication path 20 is changed, if the setting of the gradient of the inner wall 20a of the communication path 20 is adjusted, the opening diameter of the central portion of the communication path 20 is changed. There is no need to make them different. Therefore, it is not necessary to prepare a plug 24 having a different shape of the exposed surface 24a every time it is made to correspond to the tubes 4 having various inner diameters. Thereby, the plug 24 can be used as a common part for many kinds of mixed injection members 15, and the manufacturing cost of the mixed injection member 15 can be reduced. When the inner diameter dimension of the tube 4 is smaller than the opening diameter of the central portion of the communication passage 20, the diameter of the communication passage 20 is gradually increased from both ends toward the central portion, and the central portion of the communication passage 20 is plugged. It is preferable to align with the curved surface of the 24 exposed surfaces 24a. Further, when the diameter of the communication passage 20 is gradually reduced from both ends toward the central portion, the flow velocity of the fluid flowing through the inside at the reduced diameter portion of the communication passage 20 can be increased. Therefore, even if air bubbles are attached to the inner wall 20a of the communication path 20 during the priming operation, the air bubbles can be peeled off from the inner wall 20a by the physiological saline whose flow rate is increased.

  By the way, in the said embodiment, although the exposed surface 24a of the plug body 24 was formed in circular arc shape and faced the communicating path 20, this invention is not limited to this. For example, as in the second embodiment shown in FIG. 3, the exposed surface 24 a of the plug body 24 is formed in a cylindrical shape and faces the communication path 20, in other words, the plug body 24 is the same as the central portion of the communication path 20. A through-hole having a size is opened to form a cylindrical exposed surface 24a, and the exposed surface 24a is aligned with the inner peripheral surface of the communication path 20 and the inner peripheral surface of the blood circuit 1 on a continuous surface without a step. It may be formed. Even when such a cylindrical exposed surface 24a is provided, it is possible to prevent blood from staying and air from remaining in the co-infusion member 15, and a thrombus is formed under the influence of the staying blood and residual air. Can be sufficiently suppressed. Further, if the spiral projection 25b is provided on the cover 25 of the mixed injection member 15 and a part of the insertion tube is engaged with the spiral projection 25b, the insertion tube inserted into the slit 26 can be prevented from dropping off. It is preferable.

  By the way, in each said embodiment, although comprised so that an insertion tube may be penetrated to the slit 26, this invention is not limited to this. For example, it may be avoided to form the slit 26 in the plug 24 as in the third embodiment shown in FIG. Then, a puncture tube (not shown) such as an injection needle for injecting a drug or a blood collection needle for collecting blood is punctured into the plug body 24 so that the tip of the puncture tube faces the communication path 20, and the puncture tube The communication path 20 may be communicated.

It is the schematic of a blood circuit. It is explanatory drawing of the co-injection member in 1st Embodiment, (a) is a perspective view, (b) is a top view, (c) is a front view, (d) is AA sectional drawing of (b), (e ) Is a sectional view taken along line BB in FIG. It is explanatory drawing of the co-injection member in 2nd Embodiment, (a) is a perspective view, (b) is a top view, (c) is a front view, (d) is CC sectional drawing of (b), (e ) Is a sectional view taken along the line DD of (c). It is explanatory drawing of the co-injection member in 3rd Embodiment, (a) is a perspective view, (b) is a top view, (c) is a front view, (d) is EE sectional drawing of (b), (e ) Is a sectional view taken along line FF in FIG.

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 Blood circuit 2,3 Puncture needle 4 Tube 5 Blood pump 6 Flexible tube 7,8 Drip chamber 9 Blood purifier 10 T tube 11 Infusion chamber 12 Infusion container 15 Mixed injection member 16 Housing 17 Upstream connection space 18 Downstream connection space Part 20 Communication path 20a Inner wall 22 Insertion part 24 Plug 24a Exposed surface 25 Cover 25a Through-hole 25b Helical projection 26 Slit

Claims (3)

A communication path that communicates with the upstream portion and the downstream portion of the blood circuit and through which blood can pass is provided, an insertion portion is provided on the inner wall of the communication passage, and an insertion tube is inserted into the insertion portion to connect the communication passage and the insertion tube. A mixed injection member capable of communicating,
A co-infusion member characterized in that the entire inner wall of the communication passage is formed on a continuous surface having no step with the inner peripheral surface of the blood circuit.   2. The co-infusion member according to claim 1, wherein an exposed surface exposed to the communication path in the insertion portion is formed so as to be aligned on a continuous surface having no step with the inner peripheral surface of the blood circuit.   The mixed injection member according to claim 1, wherein the insertion portion includes a stopper formed of an elastic member.

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