JP2009538898A - 糖尿病の進行を遅らせるためのｇｐｃｒアゴニストの使用 - Google Patents

糖尿病の進行を遅らせるためのｇｐｃｒアゴニストの使用 Download PDF

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Publication number
JP2009538898A
JP2009538898A JP2009512684A JP2009512684A JP2009538898A JP 2009538898 A JP2009538898 A JP 2009538898A JP 2009512684 A JP2009512684 A JP 2009512684A JP 2009512684 A JP2009512684 A JP 2009512684A JP 2009538898 A JP2009538898 A JP 2009538898A
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JP
Japan
Prior art keywords
diabetes
gpr119 agonist
gpr119
cells
patient
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Pending
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JP2009512684A
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English (en)
Japanese (ja)
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JP2009538898A5 (enExample
Inventor
マシュー・コリン・ソーア・ファイフ
ピーター・ウィドウソン
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Prosidion Ltd
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Prosidion Ltd
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Publication of JP2009538898A publication Critical patent/JP2009538898A/ja
Publication of JP2009538898A5 publication Critical patent/JP2009538898A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2009512684A 2006-06-01 2007-06-01 糖尿病の進行を遅らせるためのｇｐｃｒアゴニストの使用 Pending JP2009538898A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0610746.0A GB0610746D0 (en) 2006-06-01 2006-06-01 Method of treatment
PCT/GB2007/050313 WO2007138362A1 (en) 2006-06-01 2007-06-01 Use of gpcr agonists to delay progression of diabetes

Publications (2)

Publication Number Publication Date
JP2009538898A true JP2009538898A (ja) 2009-11-12
JP2009538898A5 JP2009538898A5 (enExample) 2012-12-27

Family

ID=36694688

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009512684A Pending JP2009538898A (ja) 2006-06-01 2007-06-01 糖尿病の進行を遅らせるためのｇｐｃｒアゴニストの使用

Country Status (5)

Country Link
US (1) US20090258816A1 (enExample)
EP (1) EP2029124A1 (enExample)
JP (1) JP2009538898A (enExample)
GB (1) GB0610746D0 (enExample)
WO (1) WO2007138362A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2010003117A (es) 2007-09-20 2010-04-01 Irm Llc Compuestos y composiciones como moduladores de la actividad de gpr119.
EP2108960A1 (en) 2008-04-07 2009-10-14 Arena Pharmaceuticals, Inc. Methods of using A G protein-coupled receptor to identify peptide YY (PYY) secretagogues and compounds useful in the treatment of conditons modulated by PYY
US20100130476A1 (en) * 2008-11-12 2010-05-27 The Scripps Research Institute Compounds that induce pancreatic beta-cell expansion
JP5378825B2 (ja) * 2009-02-17 2013-12-25 出光興産株式会社 Ｇｐｒ１１９アゴニスト
GB0904287D0 (en) 2009-03-12 2009-04-22 Prosidion Ltd Compounds for the treatment of metabolic disorders
GB0904284D0 (en) 2009-03-12 2009-04-22 Prosidion Ltd Compounds for the treatment of metabolic disorders
GB0904285D0 (en) 2009-03-12 2009-04-22 Prosidion Ltd Compounds for the treatment of metabolic disorders
US8293729B2 (en) * 2009-06-24 2012-10-23 Boehringer Ingelheim International Gmbh Compounds, pharmaceutical composition and methods relating thereto
US8481731B2 (en) * 2009-06-24 2013-07-09 Boehringer Ingelheim International Gmbh Compounds, pharmaceutical composition and methods relating thereto
US20130109703A1 (en) 2010-03-18 2013-05-02 Boehringer Ingelheim International Gmbh Combination of a GPR119 Agonist and the DPP-IV Inhibitor Linagliptin for Use in the Treatment of Diabetes and Related Conditions
GB201006167D0 (en) 2010-04-14 2010-05-26 Prosidion Ltd Compounds for the treatment of metabolic disorders
GB201006166D0 (en) 2010-04-14 2010-05-26 Prosidion Ltd Compounds for the treatment of metabolic disorders
WO2014187964A2 (en) * 2013-05-23 2014-11-27 University Of Bremen Novel treatment of metabolic diseases

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005061489A1 (en) * 2003-12-24 2005-07-07 Prosidion Limited Heterocyclic derivatives as gpcr receptor agonists

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6100042A (en) * 1993-03-31 2000-08-08 Cadus Pharmaceutical Corporation Yeast cells engineered to produce pheromone system protein surrogates, and uses therefor
EP1907383A1 (en) * 2005-06-30 2008-04-09 Prosidion Limited Gpcr agonists
US7638541B2 (en) * 2006-12-28 2009-12-29 Metabolex Inc. 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005061489A1 (en) * 2003-12-24 2005-07-07 Prosidion Limited Heterocyclic derivatives as gpcr receptor agonists

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JPN5009007272; ＭＡＹＥＴ　Ｓ: ＤＩＡＢＥＴＯＬＯＧＩＡ Ｖ４８　Ｎ．ＳＵＰＰＬ．１, 2005 *

Also Published As

Publication number Publication date
EP2029124A1 (en) 2009-03-04
WO2007138362A1 (en) 2007-12-06
US20090258816A1 (en) 2009-10-15
GB0610746D0 (en) 2006-07-12

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