JP2009537553A5 - - Google Patents

Download PDF

Info

Publication number
JP2009537553A5
JP2009537553A5 JP2009511109A JP2009511109A JP2009537553A5 JP 2009537553 A5 JP2009537553 A5 JP 2009537553A5 JP 2009511109 A JP2009511109 A JP 2009511109A JP 2009511109 A JP2009511109 A JP 2009511109A JP 2009537553 A5 JP2009537553 A5 JP 2009537553A5
Authority
JP
Japan
Prior art keywords
sleep
pharmaceutical composition
dose
period
patient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2009511109A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009537553A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2007/012105 external-priority patent/WO2007142810A2/en
Publication of JP2009537553A publication Critical patent/JP2009537553A/ja
Publication of JP2009537553A5 publication Critical patent/JP2009537553A5/ja
Pending legal-status Critical Current

Links

JP2009511109A 2006-05-19 2007-05-18 睡眠改善のための低用量ドキセピンの使用法 Pending JP2009537553A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80182406P 2006-05-19 2006-05-19
US83331906P 2006-07-25 2006-07-25
PCT/US2007/012105 WO2007142810A2 (en) 2006-05-19 2007-05-18 Methods of using low-dose doxepin for the improvement of sleep

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013161145A Division JP2013237694A (ja) 2006-05-19 2013-08-02 睡眠改善のための低用量ドキセピンの使用法

Publications (2)

Publication Number Publication Date
JP2009537553A JP2009537553A (ja) 2009-10-29
JP2009537553A5 true JP2009537553A5 (https=) 2012-01-05

Family

ID=38801962

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2009511109A Pending JP2009537553A (ja) 2006-05-19 2007-05-18 睡眠改善のための低用量ドキセピンの使用法
JP2013161145A Pending JP2013237694A (ja) 2006-05-19 2013-08-02 睡眠改善のための低用量ドキセピンの使用法
JP2015248228A Pending JP2016041757A (ja) 2006-05-19 2015-12-21 睡眠改善のための低用量ドキセピンの使用法
JP2017243448A Pending JP2018044006A (ja) 2006-05-19 2017-12-20 睡眠改善のための低用量ドキセピンの使用法

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2013161145A Pending JP2013237694A (ja) 2006-05-19 2013-08-02 睡眠改善のための低用量ドキセピンの使用法
JP2015248228A Pending JP2016041757A (ja) 2006-05-19 2015-12-21 睡眠改善のための低用量ドキセピンの使用法
JP2017243448A Pending JP2018044006A (ja) 2006-05-19 2017-12-20 睡眠改善のための低用量ドキセピンの使用法

Country Status (4)

Country Link
US (9) US8513299B2 (https=)
JP (4) JP2009537553A (https=)
CA (1) CA2687118A1 (https=)
WO (1) WO2007142810A2 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007142810A2 (en) 2006-05-19 2007-12-13 Somaxon Pharmaceuticals, Inc. Methods of using low-dose doxepin for the improvement of sleep
US20100179215A1 (en) 2006-05-19 2010-07-15 Somaxon Pharmaceuticals, Inc. Doxepin isomers and isomeric mixtures and methods of using the same to treat sleep disorders
WO2007136741A2 (en) * 2006-05-19 2007-11-29 Somaxon Pharmaceuticals, Inc. N-desmethyl-doxepin and methods of using the same to treat sleep disorders
US20100179214A1 (en) 2006-05-19 2010-07-15 Somaxon Pharmaceuticals, Inc. Doxepin trans isomers and isomeric mixtures and methods of using the same to treat sleep disorders
US20080058408A1 (en) * 2006-05-19 2008-03-06 Rogowski Roberta L Low-dose doxepin for treatment of sleep disorders in elderly patients
CA2693992C (en) 2006-07-20 2017-01-31 Somaxon Pharmaceuticals, Inc. Methods of improving the pharmacokinetics of doxepin
US20080182890A1 (en) * 2006-10-04 2008-07-31 Somaxon Pharmaceuticals, Inc. Methods of using low-dose doxepin for the improvement of sleep
WO2008052139A2 (en) 2006-10-25 2008-05-02 Somaxon Pharmaceuticals, Inc. Ultra low dose doxepin and methods of using the same to treat sleep disorders
WO2008070795A2 (en) * 2006-12-06 2008-06-12 Somaxon Pharmaceuticals, Inc. Combination therapy using low-dose doxepin for the improvement of sleep
CA2721133C (en) 2007-04-13 2018-11-06 Somaxon Pharmaceuticals, Inc. Low-dose doxepin formulations and methods of making and using the same
WO2014145045A1 (en) * 2013-03-15 2014-09-18 Tonix Pharmaceuticals, Inc. Compositions and methods for transmucosal absorption
WO2014147647A1 (en) * 2013-03-19 2014-09-25 Council Of Scientific & Industrial Research A process for the synthesis of olopatadine
WO2020185712A1 (en) * 2019-03-08 2020-09-17 Alairion, Inc. Methods for treating sleep fragmentation disorders

Family Cites Families (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3420851A (en) * 1962-12-19 1969-01-07 Pfizer & Co C Novel dibenzoxepines
FR88751E (https=) * 1963-07-09 1967-06-07
US3509175A (en) * 1963-10-14 1970-04-28 Pfizer & Co C Recovery of pure cis 11-(3-dimethylaminopropylidene) - 6,11 - dihydrodibenz(b,e)oxepine from admixture with its trans isomer
US4110438A (en) * 1977-03-21 1978-08-29 American Home Products Corporation Method of treating depression
CH646696A5 (de) * 1980-11-28 1984-12-14 Sandoz Ag Dibenzazepine, ihre herstellung und verwendung.
US5030632A (en) * 1986-09-23 1991-07-09 Sandoz Pharm. Corp. Low dose temazepam
US4833154A (en) * 1987-12-14 1989-05-23 Jean Louis Louis J Natural sleeping pill to prevent and alleviate insomnia
US5116852A (en) * 1990-12-03 1992-05-26 Bristol-Myers Squibb Co. Treatment of sleep disorders
US5332661A (en) * 1991-07-31 1994-07-26 Abbott Laboratories Reagents and methods for the quantification of total doxepins in biological fluids
US5502047A (en) * 1993-03-22 1996-03-26 Kavey; Neil B. Treatment for insomnia
US6471994B1 (en) * 1995-01-09 2002-10-29 Edward Mendell Co., Inc. Pharmaceutical excipient having improved compressibility
US6395303B1 (en) * 1996-06-10 2002-05-28 Edward Mendell Co., Inc. Process for preparing a directly compressible solid dosage form containing microcrystalline cellulose
IL116674A (en) * 1995-01-09 2003-05-29 Mendell Co Inc Edward Microcrystalline cellulose-based excipient having improved compressibility, pharmaceutical compositions containing the same and methods for the preparation of said excipient and of solid dosage form thereof
US5585115A (en) * 1995-01-09 1996-12-17 Edward H. Mendell Co., Inc. Pharmaceutical excipient having improved compressability
US6936277B2 (en) * 1995-01-09 2005-08-30 J. Rettenmaier & Soehne Gmbh & Co. Kg Pharmaceutical excipient having improved compressibility
US5948438A (en) * 1995-01-09 1999-09-07 Edward Mendell Co., Inc. Pharmaceutical formulations having improved disintegration and/or absorptivity
US6106865A (en) * 1995-01-09 2000-08-22 Edward Mendell Co., Inc. Pharmaceutical excipient having improved compressibility
US5733578A (en) * 1995-11-15 1998-03-31 Edward Mendell Co., Inc. Directly compressible high load acetaminophen formulations
US6852336B2 (en) * 1995-11-15 2005-02-08 J. Rettenmaier & Soehne Gmbh + Co. Kg Directly compressible high load acetaminophen formulations
US6391337B2 (en) * 1995-11-15 2002-05-21 Edward Mendell Co., Inc. Directly compressible high load acetaminophen formulations
US6403597B1 (en) * 1997-10-28 2002-06-11 Vivus, Inc. Administration of phosphodiesterase inhibitors for the treatment of premature ejaculation
AU2406299A (en) 1998-02-12 1999-08-30 Centrapharm Inc. Sublingual drug formulations having combined rapid onset of action and long lasting therapeutic effect
CA2341400A1 (en) 1998-08-25 2000-03-02 Sepracor, Inc. Methods and compositions employing optically pure s(+) vigabatrin
GB9904163D0 (en) 1999-02-23 1999-04-14 Bioglan Lab Ltd Pharmaceutical compositions
AR025111A1 (es) * 1999-08-13 2002-11-06 Janus Pharmaceuticals Inc Metodos y composiciones para tratar trastornos de ansiedad generalizada
US6219674B1 (en) * 1999-11-24 2001-04-17 Classen Immunotherapies, Inc. System for creating and managing proprietary product data
RU2216319C1 (ru) 1999-11-30 2003-11-20 Панацея Биотек Лимитед Быстрорастворимая фармацевтическая композиция в виде твердой лекарственной формы с пролонгированным сладким вкусом и способ ее получения
US6211229B1 (en) * 2000-02-17 2001-04-03 Neil B. Kavey Treatment of transient and short term insomnia
US6344487B1 (en) * 2000-06-05 2002-02-05 Neil B. Kavey Treatment of insomnia
AU2001287850A1 (en) * 2000-09-19 2002-04-02 Vitra Pharmaceuticals Limited Iron compositions
IL155730A0 (en) * 2000-11-03 2003-11-23 Biomedicines Inc Method for short-term and long-term drug dosimetry
CA2431335A1 (en) * 2000-12-07 2002-06-13 Newsgrade Corporation System and method for organizing, navigating and analyzing data
US20020165246A1 (en) * 2001-03-05 2002-11-07 Andrew Holman Administration of sleep restorative agents
WO2003004009A1 (en) 2001-07-02 2003-01-16 Geneva Pharmaceuticals, Inc. Pharmaceutical composition
US20030206978A1 (en) * 2001-11-29 2003-11-06 Bob Sherwood Agglomerated particles including an active agent coprocessed with silicified microcrystalline cellulose
US7179488B2 (en) * 2001-11-29 2007-02-20 Bob Sherwood Process for co-spray drying liquid herbal extracts with dry silicified MCC
US6863901B2 (en) * 2001-11-30 2005-03-08 Collegium Pharmaceutical, Inc. Pharmaceutical composition for compressed annular tablet with molded triturate tablet for both intraoral and oral administration
US6407128B1 (en) * 2001-12-03 2002-06-18 Elan Pharmaceuticals, Inc. Method for increasing the bioavailability of metaxalone
WO2003066029A2 (en) 2002-02-07 2003-08-14 Pharmacia Corporation Pharmaceutical dosage form for mucosal delivery
JP2006500366A (ja) * 2002-08-15 2006-01-05 ワイス 温度調節機能障害の治療ための５ＨＴ２ａ受容体の拮抗
AU2003272278A1 (en) * 2002-09-05 2004-03-29 Jrs Pharma Lp Compositions for industrial applications
US20040097488A1 (en) * 2002-11-14 2004-05-20 Bernstein Joel E. Compositions and method for treating affective, painful or allergic disorders
NZ542303A (en) * 2003-03-14 2008-12-24 Nirmal Mulye A process for preparing sustained release tablets
WO2004082675A1 (en) * 2003-03-17 2004-09-30 Japan Tobacco Inc. Method for increasing the oral bioavailability of s-[2- ([[1- (2-ethylbutyl) cyclohexyl] carbonyl] amino) phenyl] 2-methylpropanethioate
US20050118261A1 (en) * 2003-06-12 2005-06-02 Oien Hal J. Compositions and methods of administering doxepin to mucosal tissue
WO2005041869A2 (en) * 2003-10-24 2005-05-12 Josef Rettenmaier & Soehne Gmbh & Co., Kg Process for co-spray drying agents with dry silicified mcc
US7482460B2 (en) * 2003-12-10 2009-01-27 Hypnion, Inc. Doxepin analogs and methods of use thereof
US7326721B2 (en) * 2003-12-10 2008-02-05 Hypnion, Inc. Doxepin analogs and methods of use thereof
PL1691811T3 (pl) * 2003-12-11 2014-12-31 Sunovion Pharmaceuticals Inc Skojarzenie leku uspokajającego i modulatora neuroprzekaźnikowego oraz sposoby poprawy jakości snu i leczenia depresji
US20050214365A1 (en) * 2004-03-24 2005-09-29 Gulf Pharmaceutical Industries [Instant dissolving tablet composition for loratidine and desloratidine]
WO2005102335A2 (en) * 2004-04-23 2005-11-03 Hypnion, Inc. Methods of treating sleep disorders
US20060228487A1 (en) * 2005-04-11 2006-10-12 J. Rettenmaier & Söehne GmbH + Co. KG Methods of combining active agents with augmented microcrystalline cellulose
US7452872B2 (en) * 2005-08-24 2008-11-18 Salix Pharmaceuticals, Inc. Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives
US20100179215A1 (en) 2006-05-19 2010-07-15 Somaxon Pharmaceuticals, Inc. Doxepin isomers and isomeric mixtures and methods of using the same to treat sleep disorders
CA2687124A1 (en) * 2006-05-19 2007-12-13 Somaxon Pharmaceuticals, Inc. Low dose doxepin formulations, including buccal, sublingual and fastmelt formulations, and uses of the same to treat insomnia
US20090042971A1 (en) * 2006-05-19 2009-02-12 Somaxon Pharmaceuticals, Inc. Method of using low-dose doxepin for the improvement of sleep
US20080058408A1 (en) * 2006-05-19 2008-03-06 Rogowski Roberta L Low-dose doxepin for treatment of sleep disorders in elderly patients
US20100179214A1 (en) 2006-05-19 2010-07-15 Somaxon Pharmaceuticals, Inc. Doxepin trans isomers and isomeric mixtures and methods of using the same to treat sleep disorders
WO2007136741A2 (en) * 2006-05-19 2007-11-29 Somaxon Pharmaceuticals, Inc. N-desmethyl-doxepin and methods of using the same to treat sleep disorders
US20090042972A1 (en) * 2006-05-19 2009-02-12 Somaxon Pharmaceuticals, Inc. Methods of using low-dose doxepin for the improvement of sleep
WO2007142810A2 (en) 2006-05-19 2007-12-13 Somaxon Pharmaceuticals, Inc. Methods of using low-dose doxepin for the improvement of sleep
CA2693992C (en) * 2006-07-20 2017-01-31 Somaxon Pharmaceuticals, Inc. Methods of improving the pharmacokinetics of doxepin
US20080182890A1 (en) * 2006-10-04 2008-07-31 Somaxon Pharmaceuticals, Inc. Methods of using low-dose doxepin for the improvement of sleep
WO2008052139A2 (en) * 2006-10-25 2008-05-02 Somaxon Pharmaceuticals, Inc. Ultra low dose doxepin and methods of using the same to treat sleep disorders
WO2008070795A2 (en) * 2006-12-06 2008-06-12 Somaxon Pharmaceuticals, Inc. Combination therapy using low-dose doxepin for the improvement of sleep
CA2721133C (en) * 2007-04-13 2018-11-06 Somaxon Pharmaceuticals, Inc. Low-dose doxepin formulations and methods of making and using the same

Similar Documents

Publication Publication Date Title
JP2009537553A5 (https=)
JP7422666B2 (ja) 睡眠時無呼吸を治療するための方法および組成物
JP2014528474A5 (https=)
US20080261931A1 (en) Method and Means of Preventing and Treating Sleep Disordered Breathing
RU2010121827A (ru) Композиции для лечения болезни паркинсона
WO2011041632A3 (en) Combination therapies for the treatment of obesity
NZ606383A (en) Methods of treating pulmonary disorders with liposomal amikacin formulations
WO2010045417A3 (en) Combination therapies for the treatment of obesity
WO2010151503A3 (en) Combination therapies for the treatment of obesity
JP4896334B2 (ja) 睡眠時呼吸障害を治療及び診断する方法並びにその方法を実施する手段
JP2019513814A5 (https=)
CN100558358C (zh) 唑尼沙胺在制备用于治疗或预防阻塞性睡眠呼吸暂停的药物中的应用
EP2964185B1 (en) Preparations for the treatment of sleep-related respiratory disorders
JP2021514380A5 (ja) 筋障害及び骨障害を処置するための化合物及び組成物
WO2010045522A3 (en) Combination therapies for the treatment of obesity
JP5197361B2 (ja) 睡眠障害を処置するための組成物および方法
JP2011157395A5 (https=)
CN101291660A (zh) 恢复正常呼吸节律的基于s-亚硝基硫醇的复方药品
JP2013503908A5 (https=)
WO2011008490A3 (en) Combination therapies for the treatment of obesity
WO2010045416A3 (en) Combination therapies for the treatment of obesity
US10179122B2 (en) Use of melatonin
WO2010045563A3 (en) Combination therapies for the treatment of obesity
Xin et al. Zhengzhou University, Zhengzhou, China
Khan et al. Sleep Disordered Breathing: Alternatives to CPAP Therapy