CA2687118A1 - Methods of using low-dose doxepin for the improvement of sleep - Google Patents

Methods of using low-dose doxepin for the improvement of sleep Download PDF

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Publication number
CA2687118A1
CA2687118A1 CA002687118A CA2687118A CA2687118A1 CA 2687118 A1 CA2687118 A1 CA 2687118A1 CA 002687118 A CA002687118 A CA 002687118A CA 2687118 A CA2687118 A CA 2687118A CA 2687118 A1 CA2687118 A1 CA 2687118A1
Authority
CA
Canada
Prior art keywords
doxepin
sleep
period
dosage
patient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA002687118A
Other languages
English (en)
French (fr)
Inventor
Roberta L. Rogowski
Susan E. Dube
Philip Jochelson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Currax Pharmaceuticals LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38801962&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2687118(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Publication of CA2687118A1 publication Critical patent/CA2687118A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CA002687118A 2006-05-19 2007-05-18 Methods of using low-dose doxepin for the improvement of sleep Pending CA2687118A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US80182406P 2006-05-19 2006-05-19
US60/801,824 2006-05-19
US83331906P 2006-07-25 2006-07-25
US60/833,319 2006-07-25
PCT/US2007/012105 WO2007142810A2 (en) 2006-05-19 2007-05-18 Methods of using low-dose doxepin for the improvement of sleep

Publications (1)

Publication Number Publication Date
CA2687118A1 true CA2687118A1 (en) 2007-12-13

Family

ID=38801962

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002687118A Pending CA2687118A1 (en) 2006-05-19 2007-05-18 Methods of using low-dose doxepin for the improvement of sleep

Country Status (4)

Country Link
US (9) US8513299B2 (https=)
JP (4) JP2009537553A (https=)
CA (1) CA2687118A1 (https=)
WO (1) WO2007142810A2 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
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US20100227916A1 (en) * 2006-05-19 2010-09-09 Somaxon Pharmaceuticals, Inc N-desmethyl-doxepin and methods of using the same to treat sleep disorders
US8513299B2 (en) 2006-05-19 2013-08-20 Pernix Sleep, Inc. Methods of using low-dose doxepin for the improvement of sleep
US20080058408A1 (en) * 2006-05-19 2008-03-06 Rogowski Roberta L Low-dose doxepin for treatment of sleep disorders in elderly patients
US20100179215A1 (en) * 2006-05-19 2010-07-15 Somaxon Pharmaceuticals, Inc. Doxepin isomers and isomeric mixtures and methods of using the same to treat sleep disorders
WO2008011150A1 (en) 2006-07-20 2008-01-24 Somaxon Pharmaceuticals, Inc. Methods of improving the pharmacokinetics of doxepin
US20080182890A1 (en) * 2006-10-04 2008-07-31 Somaxon Pharmaceuticals, Inc. Methods of using low-dose doxepin for the improvement of sleep
WO2008052139A2 (en) 2006-10-25 2008-05-02 Somaxon Pharmaceuticals, Inc. Ultra low dose doxepin and methods of using the same to treat sleep disorders
US20110077200A1 (en) * 2006-12-06 2011-03-31 Somaxon Pharmaceuticals, Inc. Combination therapy using low-dose doxepin for the improvement of sleep
CA2721133C (en) 2007-04-13 2018-11-06 Somaxon Pharmaceuticals, Inc. Low-dose doxepin formulations and methods of making and using the same
WO2014145045A1 (en) * 2013-03-15 2014-09-18 Tonix Pharmaceuticals, Inc. Compositions and methods for transmucosal absorption
WO2014147647A1 (en) * 2013-03-19 2014-09-25 Council Of Scientific & Industrial Research A process for the synthesis of olopatadine
WO2020185712A1 (en) * 2019-03-08 2020-09-17 Alairion, Inc. Methods for treating sleep fragmentation disorders

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JP2009537554A (ja) 2006-05-19 2009-10-29 ソマクソン ファーマシューティカルズ インコーポレイテッド 不眠症を治療するための、口腔内、舌下および急速融解製剤を含む、低用量ドキセピン製剤、ならびにその使用
US8513299B2 (en) * 2006-05-19 2013-08-20 Pernix Sleep, Inc. Methods of using low-dose doxepin for the improvement of sleep
US20100179214A1 (en) * 2006-05-19 2010-07-15 Somaxon Pharmaceuticals, Inc. Doxepin trans isomers and isomeric mixtures and methods of using the same to treat sleep disorders
US20100227916A1 (en) * 2006-05-19 2010-09-09 Somaxon Pharmaceuticals, Inc N-desmethyl-doxepin and methods of using the same to treat sleep disorders
US20100179215A1 (en) * 2006-05-19 2010-07-15 Somaxon Pharmaceuticals, Inc. Doxepin isomers and isomeric mixtures and methods of using the same to treat sleep disorders
US20080058408A1 (en) * 2006-05-19 2008-03-06 Rogowski Roberta L Low-dose doxepin for treatment of sleep disorders in elderly patients
US20090042972A1 (en) * 2006-05-19 2009-02-12 Somaxon Pharmaceuticals, Inc. Methods of using low-dose doxepin for the improvement of sleep
WO2008011150A1 (en) * 2006-07-20 2008-01-24 Somaxon Pharmaceuticals, Inc. Methods of improving the pharmacokinetics of doxepin
US20080182890A1 (en) * 2006-10-04 2008-07-31 Somaxon Pharmaceuticals, Inc. Methods of using low-dose doxepin for the improvement of sleep
WO2008052139A2 (en) * 2006-10-25 2008-05-02 Somaxon Pharmaceuticals, Inc. Ultra low dose doxepin and methods of using the same to treat sleep disorders
US20110077200A1 (en) * 2006-12-06 2011-03-31 Somaxon Pharmaceuticals, Inc. Combination therapy using low-dose doxepin for the improvement of sleep
CA2721133C (en) * 2007-04-13 2018-11-06 Somaxon Pharmaceuticals, Inc. Low-dose doxepin formulations and methods of making and using the same

Also Published As

Publication number Publication date
US20200345680A1 (en) 2020-11-05
WO2007142810A2 (en) 2007-12-13
JP2013237694A (ja) 2013-11-28
US9107898B2 (en) 2015-08-18
US9486437B2 (en) 2016-11-08
JP2018044006A (ja) 2018-03-22
US10238620B2 (en) 2019-03-26
JP2009537553A (ja) 2009-10-29
US20120245222A1 (en) 2012-09-27
US20250268858A1 (en) 2025-08-28
US20190216766A1 (en) 2019-07-18
US20150320717A1 (en) 2015-11-12
US20110178166A1 (en) 2011-07-21
WO2007142810A3 (en) 2008-03-13
US12083090B2 (en) 2024-09-10
JP2016041757A (ja) 2016-03-31
US20070281990A1 (en) 2007-12-06
US20170049743A1 (en) 2017-02-23
US10653662B2 (en) 2020-05-19
US20180125809A1 (en) 2018-05-10
US8513299B2 (en) 2013-08-20
US9861607B2 (en) 2018-01-09

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Effective date: 20120507