JP2009535429A5 - - Google Patents
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- Publication number
- JP2009535429A5 JP2009535429A5 JP2009510047A JP2009510047A JP2009535429A5 JP 2009535429 A5 JP2009535429 A5 JP 2009535429A5 JP 2009510047 A JP2009510047 A JP 2009510047A JP 2009510047 A JP2009510047 A JP 2009510047A JP 2009535429 A5 JP2009535429 A5 JP 2009535429A5
- Authority
- JP
- Japan
- Prior art keywords
- oxo
- chloro
- trifluoroethyl
- tetrahydroazepino
- piperidin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 C*C1=C/C2=C/C=C/C(/*)=C/N=C2/NC1=O Chemical compound C*C1=C/C2=C/C=C/C(/*)=C/N=C2/NC1=O 0.000 description 10
- WWHYYGUSPHHSKN-UHFFFAOYSA-N CC(C(C(N1)=O)=Nc2c1nccc2)=C Chemical compound CC(C(C(N1)=O)=Nc2c1nccc2)=C WWHYYGUSPHHSKN-UHFFFAOYSA-N 0.000 description 1
- TUHHRVVBKDNCHH-UHFFFAOYSA-O CC1=Cc2c[nH+]ccc2NC1=O Chemical compound CC1=Cc2c[nH+]ccc2NC1=O TUHHRVVBKDNCHH-UHFFFAOYSA-O 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79740006P | 2006-05-03 | 2006-05-03 | |
| US11/742,626 US7470680B2 (en) | 2006-05-03 | 2007-05-01 | Constrained compounds as CGRP-receptor antagonists |
| PCT/US2007/067998 WO2007131020A2 (en) | 2006-05-03 | 2007-05-02 | Constrained compounds as cgrp-receptor antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009535429A JP2009535429A (ja) | 2009-10-01 |
| JP2009535429A5 true JP2009535429A5 (https=) | 2010-06-17 |
Family
ID=38544174
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009510047A Pending JP2009535429A (ja) | 2006-05-03 | 2007-05-02 | Ｃｇｒｐ受容体アンタゴニストとしての束縛された化合物 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US7470680B2 (https=) |
| EP (1) | EP2013214B1 (https=) |
| JP (1) | JP2009535429A (https=) |
| KR (1) | KR20090018930A (https=) |
| AR (1) | AR060845A1 (https=) |
| AU (1) | AU2007248038A1 (https=) |
| BR (1) | BRPI0709759A2 (https=) |
| CA (1) | CA2651033A1 (https=) |
| IL (1) | IL195027A0 (https=) |
| MX (1) | MX2008013760A (https=) |
| NO (1) | NO20084564L (https=) |
| PE (1) | PE20080232A1 (https=) |
| TW (1) | TW200813063A (https=) |
| WO (1) | WO2007131020A2 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7384931B2 (en) * | 2004-11-03 | 2008-06-10 | Bristol-Myers Squibb Company | Constrained compounds as CGRP-receptor antagonists |
| EP2120564A4 (en) * | 2006-12-20 | 2011-05-04 | Merck Sharp & Dohme | BENZAZEPINE COMPOUNDS AS CGRP RECEPTOR ANTAGONISTS |
| JP2011512410A (ja) * | 2008-02-19 | 2011-04-21 | メルク・シャープ・エンド・ドーム・コーポレイション | イミダゾベンゾアゼピンｃｇｒｐ受容体アンタゴニスト |
| US8685969B2 (en) | 2010-06-16 | 2014-04-01 | Bristol-Myers Squibb Company | Carboline carboxamide compounds useful as kinase inhibitors |
| WO2017214269A1 (en) | 2016-06-08 | 2017-12-14 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| GB201707938D0 (en) | 2017-05-17 | 2017-06-28 | Univ Sheffield | Compounds |
| WO2024220626A1 (en) * | 2023-04-20 | 2024-10-24 | Azkarra Therapeutics, Inc. | Small molecule modulators of ogg1 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7205293B2 (en) | 2003-03-14 | 2007-04-17 | Merck & Co., Inc. | Benodiazepine spirohydantoin CGRP receptor antagonists |
| CA2518830A1 (en) | 2003-03-14 | 2004-09-30 | Merck & Co., Inc. | Carboxamide spirohydantoin cgrp receptor antagonists |
| JP4705908B2 (ja) * | 2003-04-15 | 2011-06-22 | メルク・シャープ・エンド・ドーム・コーポレイション | Ｃｇｒｐ受容体拮抗薬 |
| JO2355B1 (en) * | 2003-04-15 | 2006-12-12 | ميرك شارب اند دوم كوربوريشن | Hereditary calcitonin polypeptide receptor antagonists |
| WO2005000807A2 (en) | 2003-06-26 | 2005-01-06 | Merck & Co., Inc. | Benzodiazepine cgrp receptor antagonists |
| CA2529196A1 (en) | 2003-06-26 | 2005-02-17 | Merck & Co., Inc. | Benzodiazepine cgrp receptor antagonists |
| JP4705922B2 (ja) | 2004-01-29 | 2011-06-22 | メルク・シャープ・エンド・ドーム・コーポレイション | Ｃｇｒｐ受容体拮抗薬 |
| US7390798B2 (en) | 2004-09-13 | 2008-06-24 | Merck & Co., Inc. | Carboxamide spirolactam CGRP receptor antagonists |
| CA2582593A1 (en) | 2004-10-07 | 2006-04-20 | Merck & Co., Inc. | Cgrp receptor antagonists |
| BRPI0517418A (pt) | 2004-10-13 | 2008-10-07 | Merck & Co Inc | composto, composição farmacêutica, e, métodos para antagonismo de atividade do receptor de cgrp em um mamìfero, para tratar, controlar, melhorar ou reduzir o risco de dor de cabeça, enxaqueca ou cefalgia, e de tratamento ou prevenção de dores de cabeça de enxaqueca, cefalgias, e dores de cabeça |
| AU2005295855B2 (en) | 2004-10-14 | 2011-08-18 | Merck Sharp & Dohme Corp. | CGRP receptor antagonists |
| AU2005299852B2 (en) | 2004-10-22 | 2011-08-04 | Merck Sharp & Dohme Corp. | CGRP receptor antagonists |
| US7384931B2 (en) * | 2004-11-03 | 2008-06-10 | Bristol-Myers Squibb Company | Constrained compounds as CGRP-receptor antagonists |
| US7384930B2 (en) * | 2004-11-03 | 2008-06-10 | Bristol-Myers Squibb Company | Constrained compounds as CGRP-receptor antagonists |
| CA2594940A1 (en) | 2005-01-18 | 2006-07-27 | Merck & Co., Inc. | Cgrp receptor antagonists |
| CN101208303A (zh) | 2005-03-14 | 2008-06-25 | 默克公司 | Cgrp受体拮抗剂 |
| WO2007016087A2 (en) | 2005-07-29 | 2007-02-08 | Merck & Co., Inc. | Heterocyclic benzodiazepine cgrp receptor antagonists |
| EP2120564A4 (en) | 2006-12-20 | 2011-05-04 | Merck Sharp & Dohme | BENZAZEPINE COMPOUNDS AS CGRP RECEPTOR ANTAGONISTS |
-
2007
- 2007-05-01 US US11/742,626 patent/US7470680B2/en active Active
- 2007-05-02 EP EP07761726.4A patent/EP2013214B1/en active Active
- 2007-05-02 KR KR1020087029499A patent/KR20090018930A/ko not_active Withdrawn
- 2007-05-02 MX MX2008013760A patent/MX2008013760A/es not_active Application Discontinuation
- 2007-05-02 JP JP2009510047A patent/JP2009535429A/ja active Pending
- 2007-05-02 AR ARP070101906A patent/AR060845A1/es not_active Application Discontinuation
- 2007-05-02 WO PCT/US2007/067998 patent/WO2007131020A2/en not_active Ceased
- 2007-05-02 AU AU2007248038A patent/AU2007248038A1/en not_active Abandoned
- 2007-05-02 PE PE2007000536A patent/PE20080232A1/es not_active Application Discontinuation
- 2007-05-02 CA CA002651033A patent/CA2651033A1/en not_active Abandoned
- 2007-05-02 BR BRPI0709759-0A patent/BRPI0709759A2/pt not_active IP Right Cessation
- 2007-05-03 TW TW096115732A patent/TW200813063A/zh unknown
-
2008
- 2008-10-30 IL IL195027A patent/IL195027A0/en unknown
- 2008-10-30 NO NO20084564A patent/NO20084564L/no not_active Application Discontinuation
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