JP2009532332A5 - - Google Patents
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- Publication number
- JP2009532332A5 JP2009532332A5 JP2008557569A JP2008557569A JP2009532332A5 JP 2009532332 A5 JP2009532332 A5 JP 2009532332A5 JP 2008557569 A JP2008557569 A JP 2008557569A JP 2008557569 A JP2008557569 A JP 2008557569A JP 2009532332 A5 JP2009532332 A5 JP 2009532332A5
- Authority
- JP
- Japan
- Prior art keywords
- skin
- granzyme
- reduce
- subject
- rate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000003491 skin Anatomy 0.000 claims 43
- 229940121832 Granzyme B inhibitor Drugs 0.000 claims 18
- 102000001398 Granzyme Human genes 0.000 claims 11
- 108060005986 Granzyme Proteins 0.000 claims 11
- 238000000034 method Methods 0.000 claims 7
- 102000016942 Elastin Human genes 0.000 claims 6
- 108010014258 Elastin Proteins 0.000 claims 6
- 230000032683 aging Effects 0.000 claims 6
- 239000000556 agonist Substances 0.000 claims 6
- 150000001875 compounds Chemical class 0.000 claims 6
- 229920002549 elastin Polymers 0.000 claims 6
- 230000037303 wrinkles Effects 0.000 claims 6
- 108050001049 Extracellular proteins Proteins 0.000 claims 5
- 230000018109 developmental process Effects 0.000 claims 2
- 210000004209 hair Anatomy 0.000 claims 2
- 210000003780 hair follicle Anatomy 0.000 claims 2
- 239000011148 porous material Substances 0.000 claims 2
- 210000004927 skin cell Anatomy 0.000 claims 2
- 230000007306 turnover Effects 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 1
- 206010040829 Skin discolouration Diseases 0.000 claims 1
- 239000002537 cosmetic Substances 0.000 claims 1
- 230000003247 decreasing effect Effects 0.000 claims 1
- 238000002845 discoloration Methods 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 230000037370 skin discoloration Effects 0.000 claims 1
- 230000037394 skin elasticity Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78035206P | 2006-03-09 | 2006-03-09 | |
| US60/780,352 | 2006-03-09 | ||
| US79735206P | 2006-05-04 | 2006-05-04 | |
| US60/797,352 | 2006-05-04 | ||
| PCT/CA2007/000396 WO2007101354A1 (en) | 2006-03-09 | 2007-03-09 | Methods of treating, reducing and inhibiting the appearance of ageing in the skin |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013112324A Division JP2013173794A (ja) | 2006-03-09 | 2013-05-28 | 皮膚の老化の外観を処置、低減及び抑制する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009532332A JP2009532332A (ja) | 2009-09-10 |
| JP2009532332A5 true JP2009532332A5 (https=) | 2010-04-30 |
| JP5746813B2 JP5746813B2 (ja) | 2015-07-08 |
Family
ID=38474579
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008557569A Expired - Fee Related JP5746813B2 (ja) | 2006-03-09 | 2007-03-09 | 皮膚の老化の外観を処置、低減及び抑制する方法 |
| JP2013112324A Pending JP2013173794A (ja) | 2006-03-09 | 2013-05-28 | 皮膚の老化の外観を処置、低減及び抑制する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013112324A Pending JP2013173794A (ja) | 2006-03-09 | 2013-05-28 | 皮膚の老化の外観を処置、低減及び抑制する方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20120171144A1 (https=) |
| EP (1) | EP2002012A4 (https=) |
| JP (2) | JP5746813B2 (https=) |
| CA (1) | CA2644664C (https=) |
| NZ (1) | NZ571858A (https=) |
| WO (1) | WO2007101354A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2215478A4 (en) * | 2007-10-01 | 2010-10-06 | Univ British Columbia | GRANZYM A AND GRANZYM B DIAGNOSTICS |
| WO2009055934A1 (en) * | 2007-11-02 | 2009-05-07 | The University Of British Columbia | Treatment of fibrillinopathy or elastinopathy using granzyme inhibitors |
| WO2012076985A2 (en) * | 2010-12-06 | 2012-06-14 | The University Of British Columbia | Granzyme b inhibitor compositions, methods and uses for promoting wound healing |
| WO2014153666A1 (en) * | 2013-03-29 | 2014-10-02 | Vida Therapeutics, Inc. | Indoline compounds as granzyme b inhibitors |
| US9605021B2 (en) | 2013-03-29 | 2017-03-28 | Vida Therapeutics Inc. | Indoline compounds as granzyme B inhibitors |
| JP6305727B2 (ja) * | 2013-10-31 | 2018-04-04 | ポーラ化成工業株式会社 | 皮膚光老化防止用組成物 |
| US9458192B1 (en) | 2014-08-01 | 2016-10-04 | Vida Therapeutics Inc. | Covalent granzyme B inhibitors |
| US9458193B1 (en) | 2014-08-01 | 2016-10-04 | Vida Therapeutics Inc. | Proline compounds as Granzyme B inhibitors |
| AU2015296675B2 (en) | 2014-08-01 | 2020-04-30 | Vida Therapeutics, Inc. | Cyclic urea compounds as Granzyme B inhibitors |
| EP3186271A4 (en) * | 2014-08-01 | 2018-03-14 | Vida Therapeutics, Inc. | Azaindoline compounds as granzyme b inhibitors |
| US9458138B1 (en) | 2014-08-01 | 2016-10-04 | viDATherapeutics Inc. | Pyrrole compounds as granzyme B inhibitors |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000136122A (ja) * | 1998-10-28 | 2000-05-16 | Kose Corp | 皮膚外用剤 |
| EP1163900A1 (en) * | 1998-11-05 | 2001-12-19 | Protease Sciences, Incorporated | Cosmetic compositions containing human type serine protease inhibitors |
| EP1162934A4 (en) * | 1999-02-22 | 2005-01-26 | Eric F Bernstein | COMPOSITIONS AND METHODS FOR PREVENTING PHOTOVAGENING |
| US6699486B1 (en) * | 1999-11-18 | 2004-03-02 | Bolla Corporation | Treatment or prevention of photoaging and skin cancer |
| US7326692B2 (en) * | 2001-11-14 | 2008-02-05 | The University Of Chicago | Induction of immunity using inhibitors of granzymes |
| WO2003065987A2 (en) * | 2002-02-04 | 2003-08-14 | Merck & Co., Inc. | Granzyme b inhibitors |
| JP2004075661A (ja) * | 2002-06-18 | 2004-03-11 | Shiseido Co Ltd | 表皮基底膜ケアを特徴とする皮膚外用剤、皮膚基底膜構造形成促進剤および人工皮膚の製造方法 |
-
2007
- 2007-03-09 CA CA2644664A patent/CA2644664C/en not_active Expired - Fee Related
- 2007-03-09 NZ NZ571858A patent/NZ571858A/xx not_active IP Right Cessation
- 2007-03-09 EP EP07710727A patent/EP2002012A4/en not_active Ceased
- 2007-03-09 US US12/282,157 patent/US20120171144A1/en not_active Abandoned
- 2007-03-09 JP JP2008557569A patent/JP5746813B2/ja not_active Expired - Fee Related
- 2007-03-09 WO PCT/CA2007/000396 patent/WO2007101354A1/en not_active Ceased
-
2013
- 2013-05-28 JP JP2013112324A patent/JP2013173794A/ja active Pending
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