CA2644664C - Methods of treating, reducing and inhibiting the appearance of ageing in the skin - Google Patents

Methods of treating, reducing and inhibiting the appearance of ageing in the skin Download PDF

Info

Publication number
CA2644664C
CA2644664C CA2644664A CA2644664A CA2644664C CA 2644664 C CA2644664 C CA 2644664C CA 2644664 A CA2644664 A CA 2644664A CA 2644664 A CA2644664 A CA 2644664A CA 2644664 C CA2644664 C CA 2644664C
Authority
CA
Canada
Prior art keywords
skin
subject
appearance
granzyme
maintaining
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2644664A
Other languages
English (en)
French (fr)
Other versions
CA2644664A1 (en
Inventor
Rani Priya Gomez Cruz
David James Granville
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of British Columbia
Original Assignee
University of British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of British Columbia filed Critical University of British Columbia
Publication of CA2644664A1 publication Critical patent/CA2644664A1/en
Application granted granted Critical
Publication of CA2644664C publication Critical patent/CA2644664C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/16Emollients or protectives, e.g. against radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/007Preparations for dry skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/10Preparations for permanently dyeing the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00Preparations for affecting hair growth
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74Biological properties of particular ingredients
    • A61K2800/78Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782Enzyme inhibitors; Enzyme antagonists
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/948Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433Serine endopeptidases (3.4.21)
    • G01N2333/96436Granzymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
CA2644664A 2006-03-09 2007-03-09 Methods of treating, reducing and inhibiting the appearance of ageing in the skin Expired - Fee Related CA2644664C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US78035206P 2006-03-09 2006-03-09
US60/780,352 2006-03-09
US79735206P 2006-05-04 2006-05-04
US60/797,352 2006-05-04
PCT/CA2007/000396 WO2007101354A1 (en) 2006-03-09 2007-03-09 Methods of treating, reducing and inhibiting the appearance of ageing in the skin

Publications (2)

Publication Number Publication Date
CA2644664A1 CA2644664A1 (en) 2007-09-13
CA2644664C true CA2644664C (en) 2016-05-03

Family

ID=38474579

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2644664A Expired - Fee Related CA2644664C (en) 2006-03-09 2007-03-09 Methods of treating, reducing and inhibiting the appearance of ageing in the skin

Country Status (6)

Country Link
US (1) US20120171144A1 (https=)
EP (1) EP2002012A4 (https=)
JP (2) JP5746813B2 (https=)
CA (1) CA2644664C (https=)
NZ (1) NZ571858A (https=)
WO (1) WO2007101354A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8426149B2 (en) * 2007-10-01 2013-04-23 The University Of British Columbia Granzyme A and granzyme B diagnostics
WO2009055934A1 (en) * 2007-11-02 2009-05-07 The University Of British Columbia Treatment of fibrillinopathy or elastinopathy using granzyme inhibitors
CA2819810A1 (en) * 2010-12-06 2012-06-14 The University Of British Columbia Granzyme b inhibitor compositions, methods and uses for promoting wound healing
WO2014153666A1 (en) * 2013-03-29 2014-10-02 Vida Therapeutics, Inc. Indoline compounds as granzyme b inhibitors
US9605021B2 (en) 2013-03-29 2017-03-28 Vida Therapeutics Inc. Indoline compounds as granzyme B inhibitors
JP6305727B2 (ja) * 2013-10-31 2018-04-04 ポーラ化成工業株式会社 皮膚光老化防止用組成物
US9458192B1 (en) 2014-08-01 2016-10-04 Vida Therapeutics Inc. Covalent granzyme B inhibitors
WO2016015159A1 (en) 2014-08-01 2016-02-04 Vida Therapeutics, Inc. Azaindoline compounds as granzyme b inhibitors
US9458138B1 (en) 2014-08-01 2016-10-04 viDATherapeutics Inc. Pyrrole compounds as granzyme B inhibitors
US9458193B1 (en) 2014-08-01 2016-10-04 Vida Therapeutics Inc. Proline compounds as Granzyme B inhibitors
AU2015296675B2 (en) 2014-08-01 2020-04-30 Vida Therapeutics, Inc. Cyclic urea compounds as Granzyme B inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000136122A (ja) * 1998-10-28 2000-05-16 Kose Corp 皮膚外用剤
EP1163900A1 (en) * 1998-11-05 2001-12-19 Protease Sciences, Incorporated Cosmetic compositions containing human type serine protease inhibitors
JP2002537346A (ja) * 1999-02-22 2002-11-05 エリック・エフ・バーンスタイン 光老化の保護用組成物および保護方法
US6699486B1 (en) * 1999-11-18 2004-03-02 Bolla Corporation Treatment or prevention of photoaging and skin cancer
US7326692B2 (en) * 2001-11-14 2008-02-05 The University Of Chicago Induction of immunity using inhibitors of granzymes
EP1474093A4 (en) * 2002-02-04 2005-02-16 Merck & Co Inc Granzyme B INHIBITORS
JP2004075661A (ja) * 2002-06-18 2004-03-11 Shiseido Co Ltd 表皮基底膜ケアを特徴とする皮膚外用剤、皮膚基底膜構造形成促進剤および人工皮膚の製造方法

Also Published As

Publication number Publication date
EP2002012A1 (en) 2008-12-17
JP2009532332A (ja) 2009-09-10
JP2013173794A (ja) 2013-09-05
WO2007101354A1 (en) 2007-09-13
JP5746813B2 (ja) 2015-07-08
US20120171144A1 (en) 2012-07-05
CA2644664A1 (en) 2007-09-13
NZ571858A (en) 2013-08-30
EP2002012A4 (en) 2011-01-05
AU2007222865A1 (en) 2007-09-13

Similar Documents

Publication Publication Date Title
CA2644664C (en) Methods of treating, reducing and inhibiting the appearance of ageing in the skin
TWI682782B (zh) 用於皮膚保養之局部投與方法及組合物
TWI862641B (zh) 具有抗老化功效之多肽及其用途
EP2961481B1 (fr) Composition dermatologique antimicrobienne topique
KR20230065274A (ko) 조직 유래된 매트리킨 조성물 및 이에 대한 방법
CN112979762B (zh) 环肽piz及其用途
JP2025529453A (ja) 皺皮および皺の外観を軽減するために低分子の化学化合物を使用する方法
AU2007222865B2 (en) Methods of treating, reducing and inhibiting the appearance of ageing in the skin
WO2007002469A2 (en) Therapeutic compositions and methods using transforming growth factor-beta mimics
EP3329905A1 (en) Topical cosmetic compositions comprising an oligopeptide against anti-aging of the skin
US8846064B2 (en) Cosmetic and pharmaceutical compositions having modified proteins in the form of a supramolecular assembly
CN115515622A (zh) 用于皮肤状况的衍生自乙酰胆碱酯酶c-末端的多肽
US20250255792A1 (en) Methods of Using a Small Molecule Chemical Compound to Reduce the Appearance of Rhytids and Wrinkles
TW201924656A (zh) 用於調節黑色素生成的方法及組成物
US20240207373A1 (en) Cyclic peptides from the c-terminus of acetylcholinesterase for treatment of skin disorders and for cosmetical use
JPWO2006121210A1 (ja) 皮膚状態改善剤
WO2025259703A1 (en) Combinations of cocoa polyphenols and amino acids for personal care or treatment, and compositions and methods thereof
CN103251518B (zh) 肝素用于皮肤美白的用途

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20220909

MKLA Lapsed

Effective date: 20210309