JP2009531433A - ＨＰＶ感染処置のためのｄｓＲＮＡ組成物および方法 - Google Patents

ＨＰＶ感染処置のためのｄｓＲＮＡ組成物および方法 Download PDF

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JP2009531433A
JP2009531433A JP2009502885A JP2009502885A JP2009531433A JP 2009531433 A JP2009531433 A JP 2009531433A JP 2009502885 A JP2009502885 A JP 2009502885A JP 2009502885 A JP2009502885 A JP 2009502885A JP 2009531433 A JP2009531433 A JP 2009531433A
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dsrna
e6ap
sequence
nucleotides
hpv
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JP2009531433A5 (enExample
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ジョン・ベンソン
ビルギット・ブラムラーゲ
ケビン・フィッツジェラルド
パメラ・タン
ハンス−ペーター・フォルンロッハー
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ノバルティス アクチエンゲゼルシャフト
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/30—Chemical structure
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    • C12N2320/00—Applications; Uses
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JP2009502885A 2006-03-24 2007-03-23 ＨＰＶ感染処置のためのｄｓＲＮＡ組成物および方法 Withdrawn JP2009531433A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78583706P 2006-03-24 2006-03-24
US82578206P 2006-09-15 2006-09-15
PCT/US2007/007241 WO2007111998A2 (en) 2006-03-24 2007-03-23 Dsrna compositions and methods for treating hpv infection

Publications (2)

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JP2009531433A true JP2009531433A (ja) 2009-09-03
JP2009531433A5 JP2009531433A5 (enExample) 2010-05-20

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JP2009502885A Withdrawn JP2009531433A (ja) 2006-03-24 2007-03-23 ＨＰＶ感染処置のためのｄｓＲＮＡ組成物および方法

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US (2) US7956177B2 (enExample)
EP (1) EP1999260A2 (enExample)
JP (1) JP2009531433A (enExample)
KR (1) KR20080106554A (enExample)
AU (1) AU2007230995B2 (enExample)
BR (1) BRPI0709147A2 (enExample)
CA (1) CA2644621A1 (enExample)
MX (1) MX2008012173A (enExample)
RU (1) RU2008141977A (enExample)
WO (1) WO2007111998A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015529654A (ja) * 2012-08-02 2015-10-08 アビオン インコーポレーテッド Ｈｐｖ感染に係わる癌の治療用組成物

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20090064A1 (es) * 2007-03-26 2009-03-02 Novartis Ag Acido ribonucleico de doble cadena para inhibir la expresion del gen e6ap humano y composicion farmaceutica que lo comprende
WO2010123365A1 (en) * 2009-04-24 2010-10-28 Academisch Ziekenhuis Leiden H.O.D.N. Lumc Increasing the immunogenicity of epithelial cells infected with human papilloma virus (hpv)
AU2009222562A1 (en) * 2009-10-01 2011-04-21 Peter Maccallum Cancer Institute Cancer therapy
WO2012016139A2 (en) * 2010-07-29 2012-02-02 Sirnaomics, Inc. Sirna compositions and methods for treatment of hpv and other infections
PL235847B1 (pl) * 2014-04-11 2020-11-02 Centrum Onkologii Inst Im Marii Sklodowskiej Curie Zestaw i sposób do wykrywania obecności onkogennych wirusów HPV
WO2021126087A1 (en) * 2019-12-18 2021-06-24 National University Of Singapore Method for treating angelman syndrome and related disorders
US20240279755A1 (en) * 2021-06-09 2024-08-22 The Regents Of The University Of Michigan Materials and methods for measuring hpv ctdna
WO2025128853A2 (en) * 2023-12-13 2025-06-19 Ultragenyx Pharmaceutical Inc. Compositions and methods for treating conditions associated with ube3a overexpression

Family Cites Families (13)

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Publication number Priority date Publication date Assignee Title
US5858987A (en) * 1995-05-05 1999-01-12 Mitotix, Inc. E6AP antisense constructs and methods of use
US8202979B2 (en) * 2002-02-20 2012-06-19 Sirna Therapeutics, Inc. RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid
DK1407044T4 (en) * 2000-12-01 2017-12-04 Max-Planck-Gesellschaft Zur Förderung Der Wss E V RNA interference mediating small RNA molecules
EP1386004A4 (en) * 2001-04-05 2005-02-16 Ribozyme Pharm Inc MODULATION OF GENE EXPRESSION ASSOCIATED WITH INFLAMMATORY PROLIFERATION AND GROWTH OF NEURITIES BY METHODS INVOLVING NUCLEIC ACID
US20030170891A1 (en) * 2001-06-06 2003-09-11 Mcswiggen James A. RNA interference mediated inhibition of epidermal growth factor receptor gene expression using short interfering nucleic acid (siNA)
CA2452653A1 (en) * 2001-07-17 2003-01-30 Anne Josephine Milner Silencing of gene expression by sirna
US7956176B2 (en) * 2002-09-05 2011-06-07 Sirna Therapeutics, Inc. RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
ATE517992T1 (de) * 2002-11-14 2011-08-15 Dharmacon Inc Funktionelle und hyperfunktionelle sirna
DE10302421A1 (de) 2003-01-21 2004-07-29 Ribopharma Ag Doppelsträngige Ribonukleinsäure mit verbesserter Wirksamkeit
PL1866414T3 (pl) * 2005-03-31 2012-10-31 Calando Pharmaceuticals Inc Inhibitory podjednostki 2 reduktazy rybonukleotydowej i ich zastosowania
NZ571568A (en) * 2006-03-31 2010-11-26 Alnylam Pharmaceuticals Inc Double-stranded RNA molecule compositions and methods for inhibiting expression of Eg5 gene
US8598333B2 (en) * 2006-05-26 2013-12-03 Alnylam Pharmaceuticals, Inc. SiRNA silencing of genes expressed in cancer
PE20090064A1 (es) 2007-03-26 2009-03-02 Novartis Ag Acido ribonucleico de doble cadena para inhibir la expresion del gen e6ap humano y composicion farmaceutica que lo comprende

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015529654A (ja) * 2012-08-02 2015-10-08 アビオン インコーポレーテッド Ｈｐｖ感染に係わる癌の治療用組成物
JP2016190845A (ja) * 2012-08-02 2016-11-10 アビオン インコーポレーテッド Ｈｐｖ感染に係わる癌の治療用組成物
JP2018109058A (ja) * 2012-08-02 2018-07-12 エンハンストバイオ インコーポレイテッド Ｈｐｖ感染に係わる癌の治療用組成物
US10221418B2 (en) 2012-08-02 2019-03-05 EnhancedBio Inc. Composition for treating cancer associated with HPV infection
JP2019194234A (ja) * 2012-08-02 2019-11-07 エンハンストバイオ インコーポレイテッド Ｈｐｖ感染に係わる癌の治療用組成物

Also Published As

Publication number Publication date
US7956177B2 (en) 2011-06-07
MX2008012173A (es) 2008-10-03
EP1999260A2 (en) 2008-12-10
WO2007111998A3 (en) 2008-05-29
AU2007230995B2 (en) 2011-08-11
RU2008141977A (ru) 2010-05-27
AU2007230995A1 (en) 2007-10-04
WO2007111998A2 (en) 2007-10-04
US20110230546A1 (en) 2011-09-22
US20090247607A1 (en) 2009-10-01
KR20080106554A (ko) 2008-12-08
BRPI0709147A2 (pt) 2011-06-28
CA2644621A1 (en) 2007-10-04

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