JP2009518438A5 - - Google Patents
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- Publication number
- JP2009518438A5 JP2009518438A5 JP2008544572A JP2008544572A JP2009518438A5 JP 2009518438 A5 JP2009518438 A5 JP 2009518438A5 JP 2008544572 A JP2008544572 A JP 2008544572A JP 2008544572 A JP2008544572 A JP 2008544572A JP 2009518438 A5 JP2009518438 A5 JP 2009518438A5
- Authority
- JP
- Japan
- Prior art keywords
- agent
- stem cell
- specific molecule
- tumor stem
- tumor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 206010028980 Neoplasm Diseases 0.000 claims 6
- 239000003795 chemical substances by application Substances 0.000 claims 6
- 210000000130 stem cell Anatomy 0.000 claims 6
- 108020004414 DNA Proteins 0.000 claims 4
- 102000053602 DNA Human genes 0.000 claims 4
- 108020004682 Single-Stranded DNA Proteins 0.000 claims 4
- 102000004190 Enzymes Human genes 0.000 claims 2
- 108090000790 Enzymes Proteins 0.000 claims 2
- 239000013043 chemical agent Substances 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 230000002401 inhibitory effect Effects 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 230000004614 tumor growth Effects 0.000 claims 1
Claims (10)
- 腫瘍幹細胞を阻害するための医薬の製造における腫瘍幹細胞特異的分子を化学的に修飾する剤の使用。
- 腫瘍幹細胞特異的分子が合成されベル形の娘核に分離される、請求項１記載の使用。
- 腫瘍幹細胞特異的分子が単鎖DNA（ssDNA）である、請求項１記載の使用。
- 剤が化学的剤である、請求項１記載の使用。
- 剤が酵素である、請求項１記載の使用。
- 患者の腫瘍増殖を阻害するための医薬の製造における腫瘍幹細胞特異的分子を化学的に修飾する剤の使用。
- 腫瘍幹細胞特異的分子が合成されベル形の娘核に分離される、請求項６記載の使用。
- 腫瘍幹細胞特異的分子が単鎖DNA（ssDNA）である、請求項６記載の使用。
- 剤が化学的剤である、請求項６記載の使用。
- 剤が酵素である、請求項６記載の使用。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74895105P | 2005-12-09 | 2005-12-09 | |
| PCT/US2006/047136 WO2007067795A2 (en) | 2005-12-09 | 2006-12-08 | Methods for identifying and targeting tumor stem cells based on nuclear morphology |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009518438A JP2009518438A (ja) | 2009-05-07 |
| JP2009518438A5 true JP2009518438A5 (ja) | 2009-11-19 |
Family
ID=38099345
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008544572A Withdrawn JP2009518438A (ja) | 2005-12-09 | 2006-12-08 | 核形態に基づく腫瘍幹細胞の同定および標的のための方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20090304662A1 (ja) |
| EP (1) | EP1963490A2 (ja) |
| JP (1) | JP2009518438A (ja) |
| KR (1) | KR20080079302A (ja) |
| CN (1) | CN101426903A (ja) |
| AU (1) | AU2006321710A1 (ja) |
| BR (1) | BRPI0619599A2 (ja) |
| CA (1) | CA2632754A1 (ja) |
| IL (1) | IL191746A0 (ja) |
| RU (1) | RU2008127844A (ja) |
| WO (1) | WO2007067795A2 (ja) |
| ZA (1) | ZA200804973B (ja) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101209833B1 (ko) * | 2004-06-17 | 2012-12-07 | 메사추세츠 인스티튜트 오브 테크놀로지 | 핵 형태에 기초하여 줄기 세포를 동정하는 방법 |
| JP5171945B2 (ja) * | 2007-06-13 | 2013-03-27 | マサチューセッツ インスティテュート オブ テクノロジー | 腫瘍増殖を阻害する方法および薬剤 |
| IT1392908B1 (it) | 2008-09-29 | 2012-04-02 | Italfarmaco Spa | Uso degli inibitori delle istone-deacetilasi per la cura di sindromi mieloproliferative philadelphia-negative |
| US8217079B2 (en) | 2010-03-26 | 2012-07-10 | Italfarmaco Spa | Method for treating Philadelphia-negative myeloproliferative syndromes |
| KR20140016241A (ko) | 2010-10-25 | 2014-02-07 | 메사추세츠 인스티튜트 오브 테크놀로지 | 상처 치유 메타카리오틱 줄기 세포 및 그 사용방법 |
| US20140369934A1 (en) * | 2011-06-02 | 2014-12-18 | Massachusetts Institute Of Technology | dsRNA/DNA Hybrid Genome Replication Intermediate Of Metakaryotic Stem Cells |
| CN110118875B (zh) * | 2019-05-09 | 2020-08-28 | 量准(武汉)生命科技有限公司 | 一种人类唾液中c型反应性蛋白彩色成像的方法及装置 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7361336B1 (en) * | 1997-09-18 | 2008-04-22 | Ivan Bergstein | Methods of cancer therapy targeted against a cancer stem line |
| US6984522B2 (en) * | 2000-08-03 | 2006-01-10 | Regents Of The University Of Michigan | Isolation and use of solid tumor stem cells |
| KR101209833B1 (ko) * | 2004-06-17 | 2012-12-07 | 메사추세츠 인스티튜트 오브 테크놀로지 | 핵 형태에 기초하여 줄기 세포를 동정하는 방법 |
-
2006
- 2006-12-08 WO PCT/US2006/047136 patent/WO2007067795A2/en active Application Filing
- 2006-12-08 EP EP06847546A patent/EP1963490A2/en not_active Withdrawn
- 2006-12-08 KR KR1020087016673A patent/KR20080079302A/ko not_active Application Discontinuation
- 2006-12-08 JP JP2008544572A patent/JP2009518438A/ja not_active Withdrawn
- 2006-12-08 CN CNA2006800525889A patent/CN101426903A/zh active Pending
- 2006-12-08 US US12/085,533 patent/US20090304662A1/en not_active Abandoned
- 2006-12-08 AU AU2006321710A patent/AU2006321710A1/en not_active Abandoned
- 2006-12-08 RU RU2008127844/13A patent/RU2008127844A/ru not_active Application Discontinuation
- 2006-12-08 CA CA002632754A patent/CA2632754A1/en not_active Abandoned
- 2006-12-08 BR BRPI0619599-7A patent/BRPI0619599A2/pt not_active Application Discontinuation
-
2008
- 2008-05-27 IL IL191746A patent/IL191746A0/en unknown
- 2008-06-06 ZA ZA200804973A patent/ZA200804973B/xx unknown
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