JP2009517406A - Ｉｌ−２１受容体アンタゴニスト - Google Patents
Ｉｌ−２１受容体アンタゴニスト Download PDFInfo
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| US6307024B1 (en) | 1999-03-09 | 2001-10-23 | Zymogenetics, Inc. | Cytokine zalpha11 Ligand |
| JP5322653B2 (ja) * | 2005-11-28 | 2013-10-23 | ザイモジェネティクス， インコーポレイテッド | Ｉｌ−２１アンタゴニスト |
| JP5745274B2 (ja) | 2007-12-07 | 2015-07-08 | ザイモジェネティクス， インコーポレイテッド | 抗ヒトｉｌ−２１モノクローナル抗体 |
| JP5913103B2 (ja) | 2009-09-14 | 2016-04-27 | ザ リージェンツ オブ ザ ユニバーシティ オブ コロラド，ア ボディー コーポレイトＴＨＥ ＲＥＧＥＮＴＳ ＯＦ ＴＨＥ ＵＮＩＶＥＲＳＩＴＹ ＯＦ ＣＯＬＯＲＡＤＯ，ａ ｂｏｄｙ ｃｏｒｐｏｒａｔｅ | 酵母ベースの免疫療法組成物を含む組合せ物及び被験者のスクリーニング方法 |
| WO2013096732A2 (en) * | 2011-12-23 | 2013-06-27 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of treating or preventing viral diseases by blocking interleukin-21 |
| US9823246B2 (en) | 2011-12-28 | 2017-11-21 | The Board Of Trustees Of The Leland Stanford Junior University | Fluorescence enhancing plasmonic nanoscopic gold films and assays based thereon |
| DE102014101565A1 (de) * | 2013-11-08 | 2015-05-13 | Sartorius Lab Instruments Gmbh & Co. Kg | Komparatorwaage mit abnehmbarem Klimamodul |
| AR099625A1 (es) * | 2014-03-21 | 2016-08-03 | Lilly Co Eli | Anticuerpos de il-21 |
| PT3128997T (pt) | 2014-04-08 | 2020-09-04 | Boston Pharmaceuticals Inc | Moléculas de ligação específicas para il-21 e suas utilizações |
| EP3215846B1 (en) | 2014-11-05 | 2020-03-11 | Nirmidas Biotech, Inc. | Metal composites for enhanced imaging |
| CA2978449A1 (en) | 2015-03-02 | 2016-09-09 | 180 Therapeutics Lp | Method of treating a localized fibrotic disorder using an il-33 antagonist |
| CA3071376A1 (en) | 2017-08-03 | 2019-02-07 | Amgen Inc. | Interleukin-21 muteins and methods of treatment |
| AU2019207895A1 (en) | 2018-01-12 | 2020-06-18 | Amgen Inc. | Anti-PD-1 antibodies and methods of treatment |
| US12012441B2 (en) | 2020-10-26 | 2024-06-18 | Neptune Biosciences Llc | Engineered human IL-21 cytokines and methods for using the same |
| CN114990206B (zh) * | 2022-06-02 | 2023-04-07 | 中国医学科学院皮肤病医院(中国医学科学院皮肤病研究所) | Common γ-chain受体作为药物靶点在制备治疗狼疮性肾炎药物中的应用 |
| EP4572772A1 (en) | 2022-08-17 | 2025-06-25 | Capstan Therapeutics, Inc. | Conditioning for in vivo immune cell engineering |
Citations (2)
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| WO2001077171A2 (en) * | 2000-04-05 | 2001-10-18 | Zymogenetics, Inc. | Soluble zalpha11 cytokine receptors |
| JP2005306757A (ja) * | 2004-04-20 | 2005-11-04 | National Institute Of Advanced Industrial & Technology | 抗インターロイキン２１受容体（ｉｌ−２１ｒ）抗体および本抗体を産生するハイブリドーマ |
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| JP3255699B2 (ja) * | 1992-04-23 | 2002-02-12 | 味の素株式会社 | ヒトＩＬ−２レセプターγ鎖分子 |
| TWI239847B (en) * | 1997-12-02 | 2005-09-21 | Elan Pharm Inc | N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease |
| US6057128A (en) * | 1998-03-17 | 2000-05-02 | Genetics Institute, Inc. | MU-1, member of the cytokine receptor family |
| US6803451B2 (en) | 1998-09-23 | 2004-10-12 | Zymogenetics, Inc. | Cytokine receptor zalpha11 polypeptides |
| US6576744B1 (en) | 1998-09-23 | 2003-06-10 | Zymogenetics, Inc. | Cytokine receptor zalpha11 |
| AU2003230834A1 (en) | 2002-04-09 | 2003-10-27 | Beth Israel Deaconess Medical Center, Inc. | Antagonists of il-21 and modulation of il-21-mediated t cell responses |
| US20040016010A1 (en) * | 2002-04-17 | 2004-01-22 | Marion Kasaian | IL-21 receptor knockout animal and methods of use thereof |
| KR101228124B1 (ko) * | 2002-06-14 | 2013-01-31 | 이뮤노메딕스, 인코오포레이티드 | 단클론 항체 ｐａｍ4 및 췌장암의 진단 및 치료를 위한이들의 용도 |
| KR20050037552A (ko) * | 2002-07-15 | 2005-04-22 | 와이어쓰 | Ｔ 헬퍼(ｔｈ) 세포 발생 및 기능을 조절하는 방법 및조성물 |
| JP4914209B2 (ja) * | 2003-03-14 | 2012-04-11 | ワイス | ヒトｉｌ−２１受容体に対する抗体および該抗体の使用 |
| MXPA05010035A (es) * | 2003-03-21 | 2005-11-17 | Wyeth Corp | Tratamiento de desordenes inmunologicos usando agonistas de interleucina-21/receptor de interleucina-21. |
| BRPI0510996A (pt) * | 2004-05-19 | 2007-12-04 | Wyeth Corp | métodos para melhorar um sintoma de um distúrbio atópico, e para tratar ou prevenir um distúrbio atópico em um paciente, métodos para modular a produção de igg e ige em uma célula, e nìveis relativos de ige e igg, composição farmacêutica, recipiente, métodos para avaliar um paciente tendo ou suspeito de ter um distúrbio atópico, e para avaliar um paciente quanto ao risco de um distúrbio atópico |
| TWI396686B (zh) * | 2004-05-21 | 2013-05-21 | Takeda Pharmaceutical | 環狀醯胺衍生物、以及其製品和用法 |
| US20070111941A1 (en) | 2004-06-09 | 2007-05-17 | Zymogenetics, Inc. | Cytokine receptor zalpha11 |
| US20060039902A1 (en) * | 2004-08-05 | 2006-02-23 | Young Deborah A | Antagonizing interleukin-21 receptor activity |
| ITRM20040586A1 (it) | 2004-11-29 | 2005-02-28 | Giuliani Spa | Epitopi antigenici dell'interleuchina-21, anticorpi relativi e loro uso in campo medico. |
| JP5322653B2 (ja) | 2005-11-28 | 2013-10-23 | ザイモジェネティクス， インコーポレイテッド | Ｉｌ−２１アンタゴニスト |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001077171A2 (en) * | 2000-04-05 | 2001-10-18 | Zymogenetics, Inc. | Soluble zalpha11 cytokine receptors |
| JP2005306757A (ja) * | 2004-04-20 | 2005-11-04 | National Institute Of Advanced Industrial & Technology | 抗インターロイキン２１受容体（ｉｌ−２１ｒ）抗体および本抗体を産生するハイブリドーマ |
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