JP2009516843A5 - - Google Patents
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- Publication number
- JP2009516843A5 JP2009516843A5 JP2008541822A JP2008541822A JP2009516843A5 JP 2009516843 A5 JP2009516843 A5 JP 2009516843A5 JP 2008541822 A JP2008541822 A JP 2008541822A JP 2008541822 A JP2008541822 A JP 2008541822A JP 2009516843 A5 JP2009516843 A5 JP 2009516843A5
- Authority
- JP
- Japan
- Prior art keywords
- parent
- ion
- precursor
- ions
- mode
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000002500 ions Chemical class 0.000 claims 211
- OZAIFHULBGXAKX-UHFFFAOYSA-N precursor Substances N#CC(C)(C)N=NC(C)(C)C#N OZAIFHULBGXAKX-UHFFFAOYSA-N 0.000 claims 131
- 238000006062 fragmentation reaction Methods 0.000 claims 64
- 238000006243 chemical reaction Methods 0.000 claims 32
- 238000001077 electron transfer detection Methods 0.000 claims 12
- 238000010494 dissociation reaction Methods 0.000 claims 11
- 230000005593 dissociations Effects 0.000 claims 11
- 238000001211 electron capture detection Methods 0.000 claims 10
- 238000005040 ion trap Methods 0.000 claims 10
- 239000003153 chemical reaction reagent Substances 0.000 claims 6
- 238000004949 mass spectrometry Methods 0.000 claims 6
- 238000003795 desorption Methods 0.000 claims 3
- 230000001133 acceleration Effects 0.000 claims 2
- 238000000688 desorption electrospray ionisation Methods 0.000 claims 2
- 230000002255 enzymatic Effects 0.000 claims 2
- 238000004992 fast atom bombardment mass spectroscopy Methods 0.000 claims 2
- 238000000816 matrix-assisted laser desorption--ionisation Methods 0.000 claims 2
- 230000005405 multipole Effects 0.000 claims 2
- 238000011144 upstream manufacturing Methods 0.000 claims 2
- 102100017796 APP Human genes 0.000 claims 1
- 108060000460 APP Proteins 0.000 claims 1
- 206010013474 Distal ileal obstruction syndrome Diseases 0.000 claims 1
- 238000004252 FT/ICR mass spectrometry Methods 0.000 claims 1
- 230000035693 Fab Effects 0.000 claims 1
- 239000008186 active pharmaceutical agent Substances 0.000 claims 1
- 238000000065 atmospheric pressure chemical ionisation Methods 0.000 claims 1
- 230000015556 catabolic process Effects 0.000 claims 1
- 238000000451 chemical ionisation Methods 0.000 claims 1
- 238000001360 collision-induced dissociation Methods 0.000 claims 1
- 229920001940 conductive polymer Polymers 0.000 claims 1
- 230000004059 degradation Effects 0.000 claims 1
- 238000006731 degradation reaction Methods 0.000 claims 1
- 230000029087 digestion Effects 0.000 claims 1
- 230000005684 electric field Effects 0.000 claims 1
- 238000000132 electrospray ionisation Methods 0.000 claims 1
- 238000010265 fast atom bombardment Methods 0.000 claims 1
- 238000009616 inductively coupled plasma Methods 0.000 claims 1
- 201000002161 intrahepatic cholestasis of pregnancy Diseases 0.000 claims 1
- 238000001698 laser desorption ionisation Methods 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- PXHVJJICTQNCMI-RNFDNDRNSA-N nickel-63 Chemical compound [63Ni] PXHVJJICTQNCMI-RNFDNDRNSA-N 0.000 claims 1
- 238000004150 penning trap Methods 0.000 claims 1
- 230000002285 radioactive Effects 0.000 claims 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims 1
- 229910052710 silicon Inorganic materials 0.000 claims 1
- 239000010703 silicon Substances 0.000 claims 1
- 239000007921 spray Substances 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0523811.8A GB0523811D0 (en) | 2005-11-23 | 2005-11-23 | Mass stectrometer |
| GB0523811.8 | 2005-11-23 | ||
| US11/286,262 | 2005-11-23 | ||
| US11/286,262 US20060138320A1 (en) | 2002-07-24 | 2005-11-23 | Mass spectrometer |
| PCT/GB2006/004387 WO2007060437A2 (fr) | 2005-11-23 | 2006-11-23 | Spectrometre de masse |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009516843A JP2009516843A (ja) | 2009-04-23 |
| JP2009516843A5 true JP2009516843A5 (fr) | 2010-01-14 |
| JP4959713B2 JP4959713B2 (ja) | 2012-06-27 |
Family
ID=35601031
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008541822A Expired - Fee Related JP4959713B2 (ja) | 2005-11-23 | 2006-11-23 | 質量分析計 |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1952425A2 (fr) |
| JP (1) | JP4959713B2 (fr) |
| CA (2) | CA2628927C (fr) |
| GB (4) | GB0523811D0 (fr) |
| WO (1) | WO2007060437A2 (fr) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0806725D0 (en) * | 2008-04-14 | 2008-05-14 | Micromass Ltd | Mass spectrometer |
| GB0810125D0 (en) | 2008-06-03 | 2008-07-09 | Thermo Fisher Scient Bremen | Collosion cell |
| US8604419B2 (en) | 2010-02-04 | 2013-12-10 | Thermo Fisher Scientific (Bremen) Gmbh | Dual ion trapping for ion/ion reactions in a linear RF multipole trap with an additional DC gradient |
| GB201019337D0 (en) * | 2010-11-16 | 2010-12-29 | Micromass Ltd | Controlling hydrogen-deuterium exchange on a spectrum by spectrum basis |
| CA2873125A1 (fr) * | 2012-05-18 | 2013-11-21 | Micromass Uk Limited | Procede ameliore de spectrometrie de masse ms e |
| RU2673551C2 (ru) * | 2012-11-12 | 2018-11-28 | Федеральное государственное бюджетное учреждение "Научно-исследовательский институт биомедицинской химии им. В.Н. Ореховича" Российской академии медицинских наук (ФГБУ "ИБМХ" РАМН) | Протеотипический пептид q9y4w6-02 и способ масс-спектрометрического анализа содержания afg3-подобного белка человека на его основе |
| EP2945183A1 (fr) | 2012-11-22 | 2015-11-18 | Shimadzu Corporation | Spectromètre de masse quadripolaire en tandem |
| GB201406981D0 (en) * | 2014-04-17 | 2014-06-04 | Micromass Ltd | Hybrid acquisition method incorporating electron transfer dissociation triggered from fast sequential 2D MS/MS collision induced dissociation |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3300602B2 (ja) * | 1996-06-20 | 2002-07-08 | 株式会社日立製作所 | 大気圧イオン化イオントラップ質量分析方法及び装置 |
| US6323482B1 (en) * | 1997-06-02 | 2001-11-27 | Advanced Research And Technology Institute, Inc. | Ion mobility and mass spectrometer |
| JP2000241390A (ja) * | 1999-02-17 | 2000-09-08 | Japan Atom Energy Res Inst | 中性種の解離を用いる電荷逆転質量分析法 |
| US6545268B1 (en) * | 2000-04-10 | 2003-04-08 | Perseptive Biosystems | Preparation of ion pulse for time-of-flight and for tandem time-of-flight mass analysis |
| CA2340150C (fr) * | 2000-06-09 | 2005-11-22 | Micromass Limited | Methodes et appareil pour la spectrometrie de masse |
| DE60210056T2 (de) * | 2001-03-22 | 2006-11-16 | Syddansk Universitet | Massenspektrometrisches Verfahren mit Elektroneneinfang durch Ionen und Massenspektrometer zum Durchführen des Verfahrens |
| US6744040B2 (en) * | 2001-06-13 | 2004-06-01 | Bruker Daltonics, Inc. | Means and method for a quadrupole surface induced dissociation quadrupole time-of-flight mass spectrometer |
| GB0121172D0 (en) * | 2001-08-31 | 2001-10-24 | Shimadzu Res Lab Europe Ltd | A method for dissociating ions using a quadrupole ion trap device |
| JP4161125B2 (ja) * | 2002-04-24 | 2008-10-08 | 滋雄 早川 | 質量分析法および質量分析装置 |
| WO2003102545A2 (fr) * | 2002-05-31 | 2003-12-11 | Analytica Of Branford, Inc. | Procedes de fragmentation pour spectrometrie de masse |
| GB2390935A (en) * | 2002-07-16 | 2004-01-21 | Anatoli Nicolai Verentchikov | Time-nested mass analysis using a TOF-TOF tandem mass spectrometer |
| GB0305796D0 (en) * | 2002-07-24 | 2003-04-16 | Micromass Ltd | Method of mass spectrometry and a mass spectrometer |
| AU2002952747A0 (en) * | 2002-11-18 | 2002-12-05 | Ludwig Institute For Cancer Research | Method for analysing peptides |
| EP1597749A2 (fr) * | 2003-02-21 | 2005-11-23 | The Johns Hopkins University School Of Medicine | Spectrometre de masse de temps de vol en tandem |
| GB2402260B (en) * | 2003-05-30 | 2006-05-24 | Thermo Finnigan Llc | All mass MS/MS method and apparatus |
| JP4275545B2 (ja) * | 2004-02-17 | 2009-06-10 | 株式会社日立ハイテクノロジーズ | 質量分析装置 |
| DE05727506T1 (de) * | 2004-03-12 | 2007-09-06 | The University Of Virginia Patent Foundation | Elektronentransferdissoziation zur biopolymer-sequenzanalyse |
-
2005
- 2005-11-23 GB GBGB0523811.8A patent/GB0523811D0/en not_active Ceased
-
2006
- 2006-11-23 EP EP06808660A patent/EP1952425A2/fr not_active Withdrawn
- 2006-11-23 CA CA2628927A patent/CA2628927C/fr not_active Expired - Fee Related
- 2006-11-23 GB GB0816196A patent/GB2451963B/en active Active
- 2006-11-23 GB GB0801092A patent/GB2443570B/en active Active
- 2006-11-23 CA CA2835042A patent/CA2835042A1/fr not_active Abandoned
- 2006-11-23 GB GB0623377A patent/GB2435714B/en active Active
- 2006-11-23 WO PCT/GB2006/004387 patent/WO2007060437A2/fr active Application Filing
- 2006-11-23 JP JP2008541822A patent/JP4959713B2/ja not_active Expired - Fee Related
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