JP2009516747A5 - - Google Patents
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- Publication number
- JP2009516747A5 JP2009516747A5 JP2008542425A JP2008542425A JP2009516747A5 JP 2009516747 A5 JP2009516747 A5 JP 2009516747A5 JP 2008542425 A JP2008542425 A JP 2008542425A JP 2008542425 A JP2008542425 A JP 2008542425A JP 2009516747 A5 JP2009516747 A5 JP 2009516747A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- alkyl
- independently
- carbocyclyl
- heterocyclyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 *C(BC(*1)(*C2(*)*)*C2(*)N[U][U]*)(C2)C12I Chemical compound *C(BC(*1)(*C2(*)*)*C2(*)N[U][U]*)(C2)C12I 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73891905P | 2005-11-22 | 2005-11-22 | |
| US60/738,919 | 2005-11-22 | ||
| PCT/US2006/045151 WO2007062093A2 (en) | 2005-11-22 | 2006-11-21 | Combination therapy for the treatment of cancer comprising a metalloprotease inhibitor |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009516747A JP2009516747A (ja) | 2009-04-23 |
| JP2009516747A5 true JP2009516747A5 (https=) | 2010-01-14 |
| JP5256042B2 JP5256042B2 (ja) | 2013-08-07 |
Family
ID=37994504
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008542425A Expired - Fee Related JP5256042B2 (ja) | 2005-11-22 | 2006-11-21 | 癌の処置のための併用療法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8324194B2 (https=) |
| EP (1) | EP1951242A2 (https=) |
| JP (1) | JP5256042B2 (https=) |
| CA (1) | CA2628747C (https=) |
| WO (1) | WO2007062093A2 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8088737B2 (en) * | 2003-04-04 | 2012-01-03 | Incyte Corporation | Compositions, methods and kits relating to Her-2 cleavage |
| NZ543102A (en) * | 2003-04-24 | 2008-12-24 | Incyte Corp | Aza spiro alkane derivatives as inhibitors of metalloproteases |
| AU2004282189B2 (en) | 2003-10-17 | 2011-11-17 | Incyte Holdings Corporation | Substituted cyclic hydroxamates as inhibitors of matrix metalloproteinases |
| WO2007016597A2 (en) * | 2005-07-29 | 2007-02-08 | The Regents Of The University Of California | Targeting tnf-alpha converting enzyme (tace)-dependent growth factor shedding in cancer therapy |
| US7910108B2 (en) | 2006-06-05 | 2011-03-22 | Incyte Corporation | Sheddase inhibitors combined with CD30-binding immunotherapeutics for the treatment of CD30 positive diseases |
| DK2851374T3 (en) | 2007-12-14 | 2017-06-19 | Bristol Myers Squibb Co | Binding molecules to the human OX40 receptor |
| EP2438443A4 (en) * | 2009-06-02 | 2012-07-25 | Targeted Molecular Diagnostics Llc | METHOD FOR DETECTING AND QUANTIFYING THE P95 COMPONENT OF HER2 / NEU (ERBB2) |
| WO2011083391A2 (en) | 2010-01-05 | 2011-07-14 | Pfizer Inc. | Biomarkers for anti-igf-ir cancer therapy |
| PT2614082T (pt) | 2010-09-09 | 2018-12-03 | Pfizer | Moléculas de ligação a 4-1bb |
| GB201116092D0 (en) | 2011-09-16 | 2011-11-02 | Bioceros B V | Antibodies and uses thereof |
| JP6404717B2 (ja) * | 2012-03-02 | 2018-10-17 | ジェネンテック, インコーポレイテッド | アミドスピロ環状アミド及びスルホンアミド誘導体 |
| CN102600073B (zh) * | 2012-03-31 | 2014-01-01 | 莱普德制药有限公司 | 以乳酸酯为基础的氟维司群或其衍生物油性制剂及其制备方法 |
| AU2013255511B2 (en) | 2012-05-04 | 2016-01-28 | Pfizer Inc. | Prostate-associated antigens and vaccine-based immunotherapy regimens |
| SMT201800503T1 (it) | 2013-03-18 | 2018-11-09 | Janssen Pharmaceuticals Inc | Anticorpi anti-cd (ox40) umanizzati e loro usi |
| CA2909418A1 (en) * | 2013-04-18 | 2014-10-23 | Xi'an Libang Pharmaceutical Technology Co., Ltd. | Ester derivative of 7-.alpha.-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)n onyl]-estra-1,3,5(10)-triene-3,17.beta.-diol having anticancer activity and preparation method thereof |
| CN111511762B (zh) | 2017-08-21 | 2025-05-06 | 天演药业公司 | 抗cd137分子及其用途 |
| WO2019148445A1 (en) | 2018-02-02 | 2019-08-08 | Adagene Inc. | Precision/context-dependent activatable antibodies, and methods of making and using the same |
| WO2019148444A1 (en) | 2018-02-02 | 2019-08-08 | Adagene Inc. | Anti-ctla4 antibodies and methods of making and using the same |
| TW202200622A (zh) | 2020-05-13 | 2022-01-01 | 瑞士商天演藥業公司 | 用於治療癌症之組成物及方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0008172D0 (en) * | 2000-04-05 | 2000-05-24 | Astrazeneca Ab | Therapy |
| CN1729002A (zh) * | 2000-09-08 | 2006-02-01 | 法玛西雅意大利公司 | 依西美坦作为化学预防剂 |
| JP2004519490A (ja) | 2001-01-26 | 2004-07-02 | フアルマシア・イタリア・エツセ・ピー・アー | エキセメスタンによるホルモン依存性異常症の組合せ治療方法 |
| US8088737B2 (en) * | 2003-04-04 | 2012-01-03 | Incyte Corporation | Compositions, methods and kits relating to Her-2 cleavage |
| NZ543102A (en) * | 2003-04-24 | 2008-12-24 | Incyte Corp | Aza spiro alkane derivatives as inhibitors of metalloproteases |
| AU2004282189B2 (en) * | 2003-10-17 | 2011-11-17 | Incyte Holdings Corporation | Substituted cyclic hydroxamates as inhibitors of matrix metalloproteinases |
| WO2005117882A2 (en) * | 2004-04-20 | 2005-12-15 | Incyte Corporation | Hydroxamic acid derivatives as metalloprotease inhibitors |
| US7910108B2 (en) | 2006-06-05 | 2011-03-22 | Incyte Corporation | Sheddase inhibitors combined with CD30-binding immunotherapeutics for the treatment of CD30 positive diseases |
-
2006
- 2006-11-21 WO PCT/US2006/045151 patent/WO2007062093A2/en not_active Ceased
- 2006-11-21 CA CA2628747A patent/CA2628747C/en active Active
- 2006-11-21 US US11/602,659 patent/US8324194B2/en active Active
- 2006-11-21 EP EP06838238A patent/EP1951242A2/en not_active Withdrawn
- 2006-11-21 JP JP2008542425A patent/JP5256042B2/ja not_active Expired - Fee Related
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