JP2009516518A5 - - Google Patents

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Publication number
JP2009516518A5
JP2009516518A5 JP2008541543A JP2008541543A JP2009516518A5 JP 2009516518 A5 JP2009516518 A5 JP 2009516518A5 JP 2008541543 A JP2008541543 A JP 2008541543A JP 2008541543 A JP2008541543 A JP 2008541543A JP 2009516518 A5 JP2009516518 A5 JP 2009516518A5
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JP
Japan
Prior art keywords
rna molecules
specificity
regulate
expression
manufactured
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP2008541543A
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English (en)
Japanese (ja)
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JP2009516518A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/AU2006/001750 external-priority patent/WO2007056829A1/en
Publication of JP2009516518A publication Critical patent/JP2009516518A/ja
Publication of JP2009516518A5 publication Critical patent/JP2009516518A5/ja
Ceased legal-status Critical Current

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JP2008541543A 2005-11-21 2006-11-21 2種の活性鎖を有する多標的干渉rnaならびにそれらの設計および使用方法 Ceased JP2009516518A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US73864005P 2005-11-21 2005-11-21
US73844105P 2005-11-21 2005-11-21
PCT/AU2006/001750 WO2007056829A1 (en) 2005-11-21 2006-11-21 Multitargeting interfering rnas having two active strands and methods for their design and use

Publications (2)

Publication Number Publication Date
JP2009516518A JP2009516518A (ja) 2009-04-23
JP2009516518A5 true JP2009516518A5 (https=) 2012-07-26

Family

ID=38048226

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2008541543A Ceased JP2009516518A (ja) 2005-11-21 2006-11-21 2種の活性鎖を有する多標的干渉rnaならびにそれらの設計および使用方法
JP2008541541A Expired - Fee Related JP5078904B2 (ja) 2005-11-21 2006-11-21 多標的干渉rnaならびにそれらの使用および設計方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2008541541A Expired - Fee Related JP5078904B2 (ja) 2005-11-21 2006-11-21 多標的干渉rnaならびにそれらの使用および設計方法

Country Status (6)

Country Link
US (3) US20070269815A1 (https=)
EP (2) EP1951736A4 (https=)
JP (2) JP2009516518A (https=)
AU (2) AU2006315099C1 (https=)
CA (2) CA2630932A1 (https=)
WO (2) WO2007056826A1 (https=)

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GB2468477A (en) * 2009-03-02 2010-09-15 Mina Therapeutics Ltd Double stranded RNA molecule comprising siRNA and miRNA precursors
CN107129998A (zh) 2009-06-10 2017-09-05 淡马锡生命科学研究院有限公司 用于棉花中基因功能性分析的病毒诱导的基因沉默(vigs)
US8962584B2 (en) 2009-10-14 2015-02-24 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Compositions for controlling Varroa mites in bees
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US10806146B2 (en) 2011-09-13 2020-10-20 Monsanto Technology Llc Methods and compositions for weed control
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US9212363B2 (en) * 2012-05-11 2015-12-15 City Of Hope RNAI molecules with non-watson crick pairing based on artificial mutation consensus sequences to counter escape mutations
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CA2873766A1 (en) 2012-05-16 2013-11-21 Rana Therapeutics Inc. Compositions and methods for modulating atp2a2 expression
US10837014B2 (en) 2012-05-16 2020-11-17 Translate Bio Ma, Inc. Compositions and methods for modulating SMN gene family expression
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AU2013262709A1 (en) 2012-05-16 2015-01-22 Rana Therapeutics, Inc. Compositions and methods for modulating MECP2 expression
BR112014028634A2 (pt) 2012-05-16 2017-06-27 Rana Therapeutics Inc composições e métodos para modulação da expressão de utrn
MX360866B (es) 2012-05-24 2018-11-09 A B Seeds Ltd Composiciones y métodos para silenciar la expresión genética.
US9163235B2 (en) 2012-06-21 2015-10-20 MiRagen Therapeutics, Inc. Inhibitors of the miR-15 family of micro-RNAs
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US10683505B2 (en) 2013-01-01 2020-06-16 Monsanto Technology Llc Methods of introducing dsRNA to plant seeds for modulating gene expression
CN105143450A (zh) * 2013-01-08 2015-12-09 贝尼泰克生物制药有限公司 年龄相关性黄斑变性治疗
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CN106795515B (zh) * 2014-06-23 2021-06-08 孟山都技术公司 用于经由rna干扰调控基因表达的组合物和方法
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CN106604993A (zh) 2014-07-29 2017-04-26 孟山都技术公司 用于控制昆虫害虫的组合物和方法
JP6726105B2 (ja) 2014-12-15 2020-07-22 株式会社ボナック TGF−β1発現抑制のための一本鎖核酸分子
CN108064288B (zh) 2015-01-22 2021-11-26 孟山都技术公司 用于控制叶甲属的组合物和方法
WO2016161299A1 (en) 2015-04-01 2016-10-06 Arcturus Therapeutics, Inc. Therapeutic una oligomers and uses thereof
EP3302053B1 (en) 2015-06-02 2021-03-17 Monsanto Technology LLC Compositions and methods for delivery of a polynucleotide into a plant
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TW202540426A (zh) 2019-02-27 2025-10-16 美商Ionis製藥公司 Malat1表現之調節劑
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WO2005019453A2 (en) * 2001-05-18 2005-03-03 Sirna Therapeutics, Inc. RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA)
US20050187174A1 (en) * 2001-05-18 2005-08-25 Sirna Therapeutics, Inc. RNA interference mediated inhibition of intercellular adhesion molecule (ICAM) gene expression using short interfering nucleic acid (siNA)
WO2003070912A2 (en) * 2001-06-06 2003-08-28 Sirna Therapeutics, Inc. RNA INTERFERENCE MEDIATED INHIBITION OF EPIDERMAL GROWTH FACTOR RECEPTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
US20050048529A1 (en) * 2002-02-20 2005-03-03 Sirna Therapeutics, Inc. RNA interference mediated inhibition of intercellular adhesion molecule (ICAM) gene expression using short interfering nucleic acid (siNA)
US20050148530A1 (en) * 2002-02-20 2005-07-07 Sirna Therapeutics, Inc. RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
US20050209180A1 (en) * 2001-05-18 2005-09-22 Sirna Therapeutics, Inc. RNA interference mediated inhibition of hepatitis C virus (HCV) expression using short interfering nucleic acid (siNA)
CN1738648A (zh) * 2003-01-17 2006-02-22 佛罗里达大学研究基金会有限公司 小干扰rna基因治疗
JP2008511678A (ja) * 2004-09-02 2008-04-17 イェール ユニバーシティ マイクロrnaによるオンコジーンの調節

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