JP2009515524A - Ａｂｃｂ１多型バリアントスクリーニング、診断及び処置のための物質及び方法 - Google Patents

Ａｂｃｂ１多型バリアントスクリーニング、診断及び処置のための物質及び方法 Download PDF

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Publication number
JP2009515524A
JP2009515524A JP2008540194A JP2008540194A JP2009515524A JP 2009515524 A JP2009515524 A JP 2009515524A JP 2008540194 A JP2008540194 A JP 2008540194A JP 2008540194 A JP2008540194 A JP 2008540194A JP 2009515524 A JP2009515524 A JP 2009515524A
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polymorphism
seq
drug
abcb1
polymorphic variant
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JP2008540194A
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Japanese (ja)
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JP2009515524A5 (https=
Inventor
ディー． フィッグ、ウィリアム
スパールブーム、アレクサンダー
エム． シッサング、トリスタン
エル． ピーカーズ、リチャード
イー． ベイツ、スーザン
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Government of the United States of America
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Government of the United States of America
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Publication of JP2009515524A publication Critical patent/JP2009515524A/ja
Publication of JP2009515524A5 publication Critical patent/JP2009515524A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2008540194A 2005-11-10 2006-11-09 Ａｂｃｂ１多型バリアントスクリーニング、診断及び処置のための物質及び方法 Withdrawn JP2009515524A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73608305P 2005-11-10 2005-11-10
PCT/US2006/043656 WO2007058896A2 (en) 2005-11-10 2006-11-09 Materials and methods for abcb1 polymorphic variant screening, diagnosis, and treatment

Publications (2)

Publication Number Publication Date
JP2009515524A true JP2009515524A (ja) 2009-04-16
JP2009515524A5 JP2009515524A5 (https=) 2010-02-04

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ID=38049148

Family Applications (1)

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JP2008540194A Withdrawn JP2009515524A (ja) 2005-11-10 2006-11-09 Ａｂｃｂ１多型バリアントスクリーニング、診断及び処置のための物質及び方法

Country Status (6)

Country Link
US (1) US20090325156A1 (https=)
EP (1) EP1957673A2 (https=)
JP (1) JP2009515524A (https=)
AU (1) AU2006315760A1 (https=)
CA (1) CA2629155A1 (https=)
WO (1) WO2007058896A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014518375A (ja) * 2011-05-30 2014-07-28 ストリング セラピューティックス インコーポレイテッド ポイント・オブ・ケア薬物動態プロフィールによる治療薬モニタリングおよび用量投与のための方法および組成物

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007145704A2 (en) 2006-04-24 2007-12-21 Gloucester Pharmaceuticals Gemcitabine combination therapy
US8957027B2 (en) 2006-06-08 2015-02-17 Celgene Corporation Deacetylase inhibitor therapy
ATE490344T1 (de) * 2006-07-14 2010-12-15 Govt Of The Usa As Represented By The Secretary Of The Dept Of Health And Human Services Abcbi-genotypisierung zur vorhersage der mikrotubuli-stabilisatorwirkstoffinduzierten toxizität
WO2008083288A2 (en) * 2006-12-29 2008-07-10 Gloucester Pharmaceuticals Purifiction of romidepsin
EP2140033B1 (en) 2007-03-28 2012-10-10 Signal Diagnostics System and method for high resolution analysis of nucleic acids to detect sequence variations
US10669574B2 (en) 2008-11-18 2020-06-02 XCR Diagnostics, Inc. DNA amplification technology
SG10201505475XA (en) 2010-07-12 2015-09-29 Celgene Corp Romidepsin solid forms and uses thereof
US8859502B2 (en) 2010-09-13 2014-10-14 Celgene Corporation Therapy for MLL-rearranged leukemia
US20140349862A1 (en) * 2011-05-30 2014-11-27 Vuong Ngoc Trieu Methods and compositions for therapeutic drug monitoring and dosing by point of care pharmacokinetic profiling
AU2013202506B2 (en) 2012-09-07 2015-06-18 Celgene Corporation Resistance biomarkers for hdac inhibitors
AU2013202507B9 (en) 2012-11-14 2015-08-13 Celgene Corporation Inhibition of drug resistant cancer cells
RU2016117929A (ru) * 2013-10-09 2017-11-15 Флюоресентрик, Инк. Мультиплексные зонды
NZ630311A (en) 2013-12-27 2016-03-31 Celgene Corp Romidepsin formulations and uses thereof
CN105886599A (zh) * 2014-10-20 2016-08-24 江苏所罗门兄弟医学科技有限公司 一种用于ABCB1基因分型的ARMS-qPCR检测试剂盒及检测方法
CN108060230A (zh) * 2018-02-07 2018-05-22 山东德诺生物科技有限公司 用于检测rs1045642的引物探针组及其应用
CN110643699B (zh) * 2019-10-16 2020-12-01 成都仕康美生物科技有限公司 一种环孢素a代谢基因检测试剂盒及其应用方法
CN112980943B (zh) * 2021-03-31 2022-02-08 山东英盛生物技术有限公司 一种用于检测他克莫司精准用药的方法及引物、pcr试剂和试剂盒

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ2002329A3 (cs) * 1999-07-30 2002-07-17 Epidauros Biotechnologie Aktiengesellschaft Polymorfismy v lidském genu MDR-1 a jejich pouľití v diagnostických a terapeutických aplikacích
US20040115627A1 (en) * 2000-04-12 2004-06-17 Judy Raucy Compositions and methods for induction of proteins involved in xenobiotic metabolism
ATE381626T1 (de) * 2000-04-13 2008-01-15 Univ Georgetown Genetische diagnose zur feststellung von qt- verlängerungen als unerwünschte reaktion auf arzneimittel
AU2002328945A1 (en) * 2001-07-23 2003-02-24 Epidauros Biotechnologie Ag Methods for improved treatment of cancer with irinotecan based on mrp1
JP2006511218A (ja) * 2002-12-21 2006-04-06 ファイザー・プロダクツ・インク 薬物誘発性不整脈に関連する方法および組成物

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014518375A (ja) * 2011-05-30 2014-07-28 ストリング セラピューティックス インコーポレイテッド ポイント・オブ・ケア薬物動態プロフィールによる治療薬モニタリングおよび用量投与のための方法および組成物

Also Published As

Publication number Publication date
CA2629155A1 (en) 2007-05-24
EP1957673A2 (en) 2008-08-20
WO2007058896A2 (en) 2007-05-24
WO2007058896A3 (en) 2007-10-04
US20090325156A1 (en) 2009-12-31
AU2006315760A1 (en) 2007-05-24

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