JP2009515515A5 - - Google Patents

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Publication number
JP2009515515A5
JP2009515515A5 JP2008539502A JP2008539502A JP2009515515A5 JP 2009515515 A5 JP2009515515 A5 JP 2009515515A5 JP 2008539502 A JP2008539502 A JP 2008539502A JP 2008539502 A JP2008539502 A JP 2008539502A JP 2009515515 A5 JP2009515515 A5 JP 2009515515A5
Authority
JP
Japan
Prior art keywords
cell
mek inhibitor
mammalian
cells
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2008539502A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009515515A (ja
Filing date
Publication date
Priority claimed from GB0523039A external-priority patent/GB0523039D0/en
Priority claimed from GB0605998A external-priority patent/GB0605998D0/en
Application filed filed Critical
Priority claimed from PCT/GB2006/004218 external-priority patent/WO2007054720A1/en
Publication of JP2009515515A publication Critical patent/JP2009515515A/ja
Publication of JP2009515515A5 publication Critical patent/JP2009515515A5/ja
Pending legal-status Critical Current

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JP2008539502A 2005-11-11 2006-11-13 細胞の再プログラム化および遺伝子改変 Pending JP2009515515A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0523039A GB0523039D0 (en) 2005-11-11 2005-11-11 Reprogramming and genetic modification of cells
GB0605998A GB0605998D0 (en) 2006-03-24 2006-03-24 Reprogramming And Genetic Modification Of Cells
PCT/GB2006/004218 WO2007054720A1 (en) 2005-11-11 2006-11-13 Reprogramming and genetic modification of cells

Publications (2)

Publication Number Publication Date
JP2009515515A JP2009515515A (ja) 2009-04-16
JP2009515515A5 true JP2009515515A5 (enExample) 2010-01-07

Family

ID=37763882

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008539502A Pending JP2009515515A (ja) 2005-11-11 2006-11-13 細胞の再プログラム化および遺伝子改変

Country Status (6)

Country Link
EP (1) EP1957643A2 (enExample)
JP (1) JP2009515515A (enExample)
AU (1) AU2006313518A1 (enExample)
GB (2) GB2445706A (enExample)
TW (1) TW200730623A (enExample)
WO (1) WO2007054720A1 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8278104B2 (en) 2005-12-13 2012-10-02 Kyoto University Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2
US8129187B2 (en) 2005-12-13 2012-03-06 Kyoto University Somatic cell reprogramming by retroviral vectors encoding Oct3/4. Klf4, c-Myc and Sox2
CN101864392B (zh) 2005-12-13 2016-03-23 国立大学法人京都大学 核重新编程因子
US20090227032A1 (en) 2005-12-13 2009-09-10 Kyoto University Nuclear reprogramming factor and induced pluripotent stem cells
GB0701062D0 (en) * 2007-01-19 2007-02-28 Evocell Ltd Biological materials and uses thereof
US20100184051A1 (en) * 2007-05-30 2010-07-22 The General Hospital Corporation Methods of generating pluripotent cells from somatic cells
JP2008307007A (ja) 2007-06-15 2008-12-25 Bayer Schering Pharma Ag 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞
US9213999B2 (en) 2007-06-15 2015-12-15 Kyoto University Providing iPSCs to a customer
EP2090649A1 (en) 2008-02-13 2009-08-19 Fondazione Telethon Method for reprogramming differentiated cells
JP5951254B2 (ja) * 2008-03-17 2016-07-13 ザ スクリプス リサーチ インスティテュート 人工多能性幹細胞を作製するための化学的手法と遺伝的手法の組み合わせ法
AU2015201026B2 (en) * 2008-03-17 2017-03-16 The Scripps Research Institute Combined chemical and genetic approaches for generation of induced pluripotent stem cells
CN101855350B (zh) 2008-05-02 2014-12-31 国立大学法人京都大学 核重编程序方法
WO2010017562A2 (en) 2008-08-08 2010-02-11 Mayo Foundation For Medical Education And Research Induced pluripotent stem cells
JP5645197B2 (ja) * 2009-06-23 2014-12-24 学校法人日本大学 幹細胞の未分化状態を維持する新規方法
US20130029416A1 (en) 2011-07-22 2013-01-31 Tayaramma Thatava Differentiating induced pluripotent stem cells into glucose-responsive, insulin-secreting progeny
WO2016168658A1 (en) * 2015-04-15 2016-10-20 University Of Massachusetts Compositions and methods for xi chromosome reactivation
CA3038721A1 (en) 2016-09-30 2018-04-05 Mayo Foundation For Medical Education And Research Viral vectors for nuclear reprogramming

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