JP2009514922A - 舟状骨症候群の治療へのクロドロン酸の使用 - Google Patents
舟状骨症候群の治療へのクロドロン酸の使用 Download PDFInfo
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- JP2009514922A JP2009514922A JP2008539340A JP2008539340A JP2009514922A JP 2009514922 A JP2009514922 A JP 2009514922A JP 2008539340 A JP2008539340 A JP 2008539340A JP 2008539340 A JP2008539340 A JP 2008539340A JP 2009514922 A JP2009514922 A JP 2009514922A
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- Prior art keywords
- treatment
- medicament
- scaphoid
- syndrome
- clodronic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- Health & Medical Sciences (AREA)
- Physical Education & Sports Medicine (AREA)
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- Life Sciences & Earth Sciences (AREA)
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- Animal Behavior & Ethology (AREA)
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- General Chemical & Material Sciences (AREA)
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- Orthopedic Medicine & Surgery (AREA)
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- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
【解決手段】有効成分としてのクロドロン酸、その付加塩、エステル、水和物又は水和物の塩を含有する、ウマの骨粗鬆症を伴う舟状骨症候群の治療用の注射可能な溶液又は懸濁液の形態の医薬。当該医薬を用いる場合、当該治療は、数日の期間内における、当該医薬を2〜5回筋内注射することによって実施する。
【選択図】なし
Description
Claims (7)
- クロドロン酸、その付加塩、エステル、水和物又は水和物の塩の、ウマの骨粗鬆症を伴う舟状骨症候群の治療用の注射可能な溶液又は懸濁液の形態の医薬の調製への、有効成分としての使用であって、前記治療が、数日の期間内に前記医薬を2〜5回筋内注射することによって実施される使用。
- 使用される前記付加塩がアルカリ金属塩である、請求項1記載の使用。
- クロドロン酸のジナトリウム塩を使用する、請求項1又は2記載の使用。
- 前記医薬が公知のアジュバント及び賦形剤を含んでなる、請求項1から3のいずれか1項記載の使用。
- 前記治療が、1日以内に前記医薬を2〜5回筋内注射することによって実施される、請求項1から4のいずれか1項記載の使用。
- 10〜14ヵ月経過後、前記治療を1回又は2回以上反復させる、請求項1から5のいずれか1項記載の使用。
- 1回の注射あたり、0.125〜2.5mg、好ましくは0.25〜1mg、特に好ましくは約0.6mg有効成分/kg体重の投与量で前記医薬を投与する、請求項1から6のいずれか1項記載の使用。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102005053512A DE102005053512A1 (de) | 2005-11-09 | 2005-11-09 | Verwendung von Clodronsäure zur Behandlung von Podotrochlose |
DE102005053512.7 | 2005-11-09 | ||
PCT/EP2006/010753 WO2007054309A2 (de) | 2005-11-09 | 2006-11-09 | Verwendung von clodronsäure zur behandlung von podotrochlose |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2009514922A true JP2009514922A (ja) | 2009-04-09 |
JP5483879B2 JP5483879B2 (ja) | 2014-05-07 |
Family
ID=37946748
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2008539340A Active JP5483879B2 (ja) | 2005-11-09 | 2006-11-09 | 舟状骨症候群の治療へのクロドロン酸の使用 |
Country Status (12)
Country | Link |
---|---|
US (1) | US7781420B2 (ja) |
EP (1) | EP1948194B8 (ja) |
JP (1) | JP5483879B2 (ja) |
AU (1) | AU2006311227B2 (ja) |
CA (1) | CA2627942C (ja) |
DE (1) | DE102005053512A1 (ja) |
DK (1) | DK1948194T3 (ja) |
ES (1) | ES2503342T3 (ja) |
NZ (1) | NZ568215A (ja) |
PL (1) | PL1948194T3 (ja) |
PT (1) | PT1948194E (ja) |
WO (1) | WO2007054309A2 (ja) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH08510996A (ja) * | 1993-03-24 | 1996-11-19 | レイラス オサケユイチア | 骨の手術へのビスホスホネートの使用 |
JPH11513383A (ja) * | 1995-09-29 | 1999-11-16 | ノバルティス アクチェンゲゼルシャフト | ウマの舟状骨病を治療する方法 |
JP2002526412A (ja) * | 1998-10-02 | 2002-08-20 | セヴァ・サンテ・アニマル | 跛行を処置するための医薬品製剤の製造におけるビスホスホン酸誘導体の使用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7277744B2 (en) * | 1999-03-22 | 2007-10-02 | Schaefer Allan L | Early detection of inflammation and infection using infrared thermography |
US6280741B1 (en) * | 1999-08-19 | 2001-08-28 | Ed C. Jessup | Equine treatment and method of administering such treatment |
US6638920B2 (en) * | 2000-07-21 | 2003-10-28 | Merck & Co., Inc. | Compositions and methods of preventing or reducing the risk or incidence of skeletal injuries in horses |
US6635236B2 (en) * | 2001-08-10 | 2003-10-21 | Baer Knut | Method for treating podotrochlosis |
NZ535178A (en) * | 2002-03-11 | 2007-05-31 | Allan L Schaefer | Method for the evaluation of velvet antler |
-
2005
- 2005-11-09 DE DE102005053512A patent/DE102005053512A1/de not_active Withdrawn
-
2006
- 2006-11-09 NZ NZ568215A patent/NZ568215A/en unknown
- 2006-11-09 ES ES06818441.5T patent/ES2503342T3/es active Active
- 2006-11-09 EP EP06818441.5A patent/EP1948194B8/de active Active
- 2006-11-09 DK DK06818441.5T patent/DK1948194T3/da active
- 2006-11-09 PL PL06818441T patent/PL1948194T3/pl unknown
- 2006-11-09 JP JP2008539340A patent/JP5483879B2/ja active Active
- 2006-11-09 CA CA2627942A patent/CA2627942C/en active Active
- 2006-11-09 AU AU2006311227A patent/AU2006311227B2/en active Active
- 2006-11-09 US US12/084,587 patent/US7781420B2/en active Active
- 2006-11-09 PT PT68184415T patent/PT1948194E/pt unknown
- 2006-11-09 WO PCT/EP2006/010753 patent/WO2007054309A2/de active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH08510996A (ja) * | 1993-03-24 | 1996-11-19 | レイラス オサケユイチア | 骨の手術へのビスホスホネートの使用 |
JPH11513383A (ja) * | 1995-09-29 | 1999-11-16 | ノバルティス アクチェンゲゼルシャフト | ウマの舟状骨病を治療する方法 |
JP2002526412A (ja) * | 1998-10-02 | 2002-08-20 | セヴァ・サンテ・アニマル | 跛行を処置するための医薬品製剤の製造におけるビスホスホン酸誘導体の使用 |
Non-Patent Citations (1)
Title |
---|
JPN6012030623; DENOIX, J-M. et al.: EQUINE VETERINARY JOURNAL Vol.35, No.4, 2003, pp.407-413 * |
Also Published As
Publication number | Publication date |
---|---|
EP1948194A2 (de) | 2008-07-30 |
EP1948194B8 (de) | 2014-08-13 |
AU2006311227A1 (en) | 2007-05-18 |
PT1948194E (pt) | 2014-09-24 |
CA2627942C (en) | 2015-12-29 |
EP1948194B1 (de) | 2014-07-02 |
DK1948194T3 (da) | 2014-10-06 |
US20090253657A1 (en) | 2009-10-08 |
WO2007054309A2 (de) | 2007-05-18 |
NZ568215A (en) | 2011-06-30 |
JP5483879B2 (ja) | 2014-05-07 |
PL1948194T3 (pl) | 2014-12-31 |
DE102005053512A1 (de) | 2007-06-28 |
US7781420B2 (en) | 2010-08-24 |
CA2627942A1 (en) | 2007-05-18 |
ES2503342T3 (es) | 2014-10-06 |
WO2007054309A3 (de) | 2008-02-07 |
AU2006311227B2 (en) | 2012-08-30 |
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