JP2009513662A5 - - Google Patents
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- Publication number
- JP2009513662A5 JP2009513662A5 JP2008537951A JP2008537951A JP2009513662A5 JP 2009513662 A5 JP2009513662 A5 JP 2009513662A5 JP 2008537951 A JP2008537951 A JP 2008537951A JP 2008537951 A JP2008537951 A JP 2008537951A JP 2009513662 A5 JP2009513662 A5 JP 2009513662A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- tumor
- composition according
- floxuridine
- antagonistic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- ODKNJVUHOIMIIZ-RRKCRQDMSA-N floxuridine Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C(F)=C1 ODKNJVUHOIMIIZ-RRKCRQDMSA-N 0.000 claims description 9
- 229960000961 floxuridine Drugs 0.000 claims description 9
- UWKQSNNFCGGAFS-XIFFEERXSA-N irinotecan Chemical compound C1=C2C(CC)=C3CN(C(C4=C([C@@](C(=O)OC4)(O)CC)C=4)=O)C=4C3=NC2=CC=C1OC(=O)N(CC1)CCC1N1CCCCC1 UWKQSNNFCGGAFS-XIFFEERXSA-N 0.000 claims description 5
- 229960004768 irinotecan Drugs 0.000 claims description 5
- 239000008194 pharmaceutical composition Substances 0.000 claims 12
- 230000003042 antagnostic effect Effects 0.000 claims 5
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 208000037844 advanced solid tumor Diseases 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 206010061968 Gastric neoplasm Diseases 0.000 claims 1
- 208000008839 Kidney Neoplasms Diseases 0.000 claims 1
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 1
- 208000029742 colonic neoplasm Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 238000001990 intravenous administration Methods 0.000 claims 1
- 239000002502 liposome Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 208000025402 neoplasm of esophagus Diseases 0.000 claims 1
- 201000008968 osteosarcoma Diseases 0.000 claims 1
- 201000002528 pancreatic cancer Diseases 0.000 claims 1
- 208000023958 prostate neoplasm Diseases 0.000 claims 1
- 201000011109 sphenoidal sinus neoplasm Diseases 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73019905P | 2005-10-25 | 2005-10-25 | |
| US60/730,199 | 2005-10-25 | ||
| US75922506P | 2006-01-12 | 2006-01-12 | |
| US60/759,225 | 2006-01-12 | ||
| PCT/US2006/041832 WO2007050784A2 (en) | 2005-10-25 | 2006-10-25 | Fixed ratio drug combination treatments for solid tumors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009513662A JP2009513662A (ja) | 2009-04-02 |
| JP2009513662A5 true JP2009513662A5 (enExample) | 2012-11-08 |
| JP5687411B2 JP5687411B2 (ja) | 2015-03-18 |
Family
ID=37882130
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008537951A Active JP5687411B2 (ja) | 2005-10-25 | 2006-10-25 | 固形腫瘍のための定率配合薬の治療 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20100189771A1 (enExample) |
| EP (1) | EP1951239A2 (enExample) |
| JP (1) | JP5687411B2 (enExample) |
| AU (1) | AU2006306108B2 (enExample) |
| CA (1) | CA2628015C (enExample) |
| IL (1) | IL191040A (enExample) |
| WO (1) | WO2007050784A2 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA86063C2 (ru) | 2004-05-03 | 2009-03-25 | Хермес Біосайенсез, Інк. | Липосомы для снабжения лекарств |
| EP2123258A1 (en) | 2008-05-23 | 2009-11-25 | Liplasome Pharma A/S | Liposomes for drug delivery |
| DK177532B1 (en) * | 2009-09-17 | 2013-09-08 | Bio Bedst Aps | Medical use of sPLA2 hydrolysable liposomes |
| US20140050780A1 (en) | 2010-12-23 | 2014-02-20 | Ludwig Institute For Cancer Research Ltd. | Liposomal formulation of nonglycosidic ceramides and uses thereof |
| DK2768484T3 (da) | 2011-10-21 | 2019-10-07 | Jazz Pharmaceuticals Res Llc | Lyofiliserede liposomer |
| US9717724B2 (en) | 2012-06-13 | 2017-08-01 | Ipsen Biopharm Ltd. | Methods for treating pancreatic cancer using combination therapies |
| AU2013202947B2 (en) | 2012-06-13 | 2016-06-02 | Ipsen Biopharm Ltd. | Methods for treating pancreatic cancer using combination therapies comprising liposomal irinotecan |
| EP3028933A1 (en) * | 2014-12-05 | 2016-06-08 | Öhlins Racing Ab | Spring unit |
| US11318131B2 (en) | 2015-05-18 | 2022-05-03 | Ipsen Biopharm Ltd. | Nanoliposomal irinotecan for use in treating small cell lung cancer |
| PL3337467T3 (pl) | 2015-08-20 | 2021-06-14 | Ipsen Biopharm Ltd. | Terapia skojarzona z zastosowaniem liposomalnego irynotekanu i inhibitora parp do leczenia nowotworu |
| IL257149B2 (en) | 2015-08-21 | 2024-11-01 | Ipsen Biopharm Ltd | Methods for treating metastatic pancreatic cancer using combination therapies comprising liposomal irinotecan and oxaliplatin |
| MX382522B (es) | 2015-10-16 | 2025-03-13 | Ipsen Biopharm Ltd | Composiciones farmaceuticas estabilizantes de camptotecina. |
| CN107281102A (zh) * | 2016-04-11 | 2017-10-24 | 江苏竞诺择生物医药科技有限公司 | 一种用于结直肠肿瘤治疗的药物微粒组合物 |
| US11504347B1 (en) | 2016-07-22 | 2022-11-22 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| UY37341A (es) | 2016-07-22 | 2017-11-30 | Flamel Ireland Ltd | Formulaciones de gamma-hidroxibutirato de liberación modificada con farmacocinética mejorada |
| US11602512B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11986451B1 (en) | 2016-07-22 | 2024-05-21 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11602513B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US12186296B1 (en) | 2016-07-22 | 2025-01-07 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US12478604B1 (en) | 2016-07-22 | 2025-11-25 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| EP3535026A1 (en) | 2016-11-02 | 2019-09-11 | Ipsen Biopharm Limited | Treating gastric cancer using combination therapies comprising liposomal irinotecan, oxaliplatin, 5-fluoruracil (and leucovorin) |
| AU2017258901A1 (en) | 2016-12-30 | 2018-07-19 | Allarity Therapeutics Europe ApS | Methods for predicting drug responsiveness in cancer patients |
| AU2019394855B2 (en) | 2018-12-04 | 2025-02-27 | Der-Yang Tien | Stereocomplexes for the delivery of anti-cancer agents |
| WO2020178695A1 (en) | 2019-03-01 | 2020-09-10 | Flamel Ireland Limited | Gamma-hydroxybutyrate compositions having improved pharmacokinetics in the fed state |
| US11980636B2 (en) | 2020-11-18 | 2024-05-14 | Jazz Pharmaceuticals Ireland Limited | Treatment of hematological disorders |
| US11583510B1 (en) | 2022-02-07 | 2023-02-21 | Flamel Ireland Limited | Methods of administering gamma hydroxybutyrate formulations after a high-fat meal |
| US11779557B1 (en) | 2022-02-07 | 2023-10-10 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| WO2024228167A1 (en) | 2023-05-03 | 2024-11-07 | Iox Therapeutics Inc. | Inkt cell modulator liposomal compositions and methods of use |
| WO2025085591A1 (en) * | 2023-10-17 | 2025-04-24 | Jnd Therapeutics, Inc. | Low dosing regimens of floxuridine and methods of treatment of cancer using floxuridine |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1432402B1 (en) * | 2001-10-03 | 2006-11-22 | Celator Pharmaceuticals, Inc. | Compositions for delivery of drug combinations |
| JP2006522026A (ja) * | 2003-04-02 | 2006-09-28 | セレーター ファーマスーティカルズ、インク． | カンプトセシンとフルオロピリミジンとを組み合わせた組成物 |
-
2006
- 2006-10-25 WO PCT/US2006/041832 patent/WO2007050784A2/en not_active Ceased
- 2006-10-25 CA CA2628015A patent/CA2628015C/en active Active
- 2006-10-25 EP EP06836544A patent/EP1951239A2/en not_active Ceased
- 2006-10-25 US US12/091,738 patent/US20100189771A1/en not_active Abandoned
- 2006-10-25 AU AU2006306108A patent/AU2006306108B2/en active Active
- 2006-10-25 JP JP2008537951A patent/JP5687411B2/ja active Active
- 2006-10-25 US US11/586,215 patent/US7842676B2/en active Active
-
2008
- 2008-04-27 IL IL191040A patent/IL191040A/en active IP Right Grant
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