JP2009502937A5 - - Google Patents
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- Publication number
- JP2009502937A5 JP2009502937A5 JP2008524094A JP2008524094A JP2009502937A5 JP 2009502937 A5 JP2009502937 A5 JP 2009502937A5 JP 2008524094 A JP2008524094 A JP 2008524094A JP 2008524094 A JP2008524094 A JP 2008524094A JP 2009502937 A5 JP2009502937 A5 JP 2009502937A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- compound
- kinase
- abl kinase
- mutant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108091000080 Phosphotransferase Proteins 0.000 claims 10
- 102000020233 phosphotransferase Human genes 0.000 claims 10
- 150000001875 compounds Chemical class 0.000 claims 7
- 102000001253 Protein Kinase Human genes 0.000 claims 2
- 230000002401 inhibitory effect Effects 0.000 claims 2
- 230000035772 mutation Effects 0.000 claims 2
- 108060006633 protein kinase Proteins 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 230000005764 inhibitory process Effects 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70277105P | 2005-07-26 | 2005-07-26 | |
| US78516106P | 2006-03-23 | 2006-03-23 | |
| US83025706P | 2006-07-12 | 2006-07-12 | |
| PCT/US2006/028984 WO2007014250A2 (en) | 2005-07-26 | 2006-07-26 | Abl kinase inhibition |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012122081A Division JP2012158616A (ja) | 2005-07-26 | 2012-05-29 | Ａｂｌキナーゼ阻害 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009502937A JP2009502937A (ja) | 2009-01-29 |
| JP2009502937A5 true JP2009502937A5 (https=) | 2009-09-10 |
Family
ID=37683933
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008524094A Pending JP2009502937A (ja) | 2005-07-26 | 2006-07-26 | Ａｂｌキナーゼ阻害 |
| JP2012122081A Pending JP2012158616A (ja) | 2005-07-26 | 2012-05-29 | Ａｂｌキナーゼ阻害 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012122081A Pending JP2012158616A (ja) | 2005-07-26 | 2012-05-29 | Ａｂｌキナーゼ阻害 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20090298844A1 (https=) |
| EP (1) | EP1906967A4 (https=) |
| JP (2) | JP2009502937A (https=) |
| AU (1) | AU2006272609A1 (https=) |
| CA (1) | CA2616517A1 (https=) |
| WO (1) | WO2007014250A2 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2372975T3 (es) * | 2005-12-01 | 2012-01-30 | Bristol-Myers Squibb Company | Procedimientos de identificación y tratamiento de individuos que muestran cariotipos. |
| CA2658436A1 (en) * | 2006-07-26 | 2008-01-31 | Merck And Co., Inc. | A novel lactic acid formulation of mk-0457 useful for the treatment of cancer |
| JP6378171B2 (ja) | 2012-04-24 | 2018-08-22 | バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ | Ｄｎａ−ｐｋ阻害剤 |
| SI3527563T1 (sl) | 2013-03-12 | 2022-01-31 | Vertex Pharmaceuticals Incorporated | Inhibitorji DNA-PK |
| MY181020A (en) | 2013-03-15 | 2020-12-16 | Sanofi Sa | Heteroaryl compounds and uses thereof |
| TWI647220B (zh) | 2013-03-15 | 2019-01-11 | 美商西建卡爾有限責任公司 | 雜芳基化合物及其用途 |
| RU2675270C2 (ru) | 2013-10-17 | 2018-12-18 | Вертекс Фармасьютикалз Инкорпорейтед | Сокристаллы и содержащие их фармацевтические композиции |
| MA38393B1 (fr) | 2014-03-13 | 2018-11-30 | Sanofi Sa | Composés hétéroaryle et utilisations associées |
| RU2758669C2 (ru) | 2016-09-27 | 2021-11-01 | Вертекс Фармасьютикалз Инкорпорейтед | Способ лечения рака с применением сочетания днк-поражающих агентов и ингибиторов днк-пк |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2017335E (pt) * | 2001-10-05 | 2011-03-02 | Novartis Ag | Domínios da cinase abl mutados |
| MY141867A (en) * | 2002-06-20 | 2010-07-16 | Vertex Pharma | Substituted pyrimidines useful as protein kinase inhibitors |
| SG155222A1 (en) * | 2004-08-13 | 2009-09-30 | Genentech Inc | Thiazole based inhibitors of atp-utilizing enzymes |
-
2006
- 2006-07-26 AU AU2006272609A patent/AU2006272609A1/en not_active Abandoned
- 2006-07-26 JP JP2008524094A patent/JP2009502937A/ja active Pending
- 2006-07-26 US US11/989,300 patent/US20090298844A1/en not_active Abandoned
- 2006-07-26 CA CA002616517A patent/CA2616517A1/en not_active Abandoned
- 2006-07-26 EP EP06800350A patent/EP1906967A4/en not_active Withdrawn
- 2006-07-26 WO PCT/US2006/028984 patent/WO2007014250A2/en not_active Ceased
-
2012
- 2012-05-29 JP JP2012122081A patent/JP2012158616A/ja active Pending
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