JP2009501775A - 癌治療におけるチアゾール誘導体およびアナログの使用 - Google Patents
癌治療におけるチアゾール誘導体およびアナログの使用 Download PDFInfo
- Publication number
- JP2009501775A JP2009501775A JP2008522062A JP2008522062A JP2009501775A JP 2009501775 A JP2009501775 A JP 2009501775A JP 2008522062 A JP2008522062 A JP 2008522062A JP 2008522062 A JP2008522062 A JP 2008522062A JP 2009501775 A JP2009501775 A JP 2009501775A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- benzyl
- alkyl
- title compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 0 CCN(*)C1N(*S)*C(**)*1 Chemical compound CCN(*)C1N(*S)*C(**)*1 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Neurology (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Immunology (AREA)
- Psychiatry (AREA)
- Child & Adolescent Psychology (AREA)
- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US59562005P | 2005-07-21 | 2005-07-21 | |
SE0501721 | 2005-07-21 | ||
US74442206P | 2006-04-07 | 2006-04-07 | |
PCT/GB2006/002730 WO2007010273A2 (en) | 2005-07-21 | 2006-07-21 | Use of thiazole derivatives and analogues in the treatment of cancer |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2009501775A true JP2009501775A (ja) | 2009-01-22 |
JP2009501775A5 JP2009501775A5 (US07476746-20090113-C00133.png) | 2009-09-10 |
Family
ID=37669179
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2008522062A Withdrawn JP2009501775A (ja) | 2005-07-21 | 2006-07-21 | 癌治療におけるチアゾール誘導体およびアナログの使用 |
JP2008522065A Withdrawn JP2009501776A (ja) | 2005-07-21 | 2006-07-21 | 遊離脂肪酸に起因した障害におけるチアゾール誘導体およびアナログの使用 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2008522065A Withdrawn JP2009501776A (ja) | 2005-07-21 | 2006-07-21 | 遊離脂肪酸に起因した障害におけるチアゾール誘導体およびアナログの使用 |
Country Status (10)
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102005024012A1 (de) * | 2005-05-20 | 2006-11-23 | Grünenthal GmbH | Verwendung von 2,5-disubstituierten Thiazol-4-on-Derivaten in Arzneimitteln |
WO2008065409A2 (en) * | 2006-12-01 | 2008-06-05 | Betagenon Ab | Combination for use in the treatment of cancer, comprising tamoxifen or an aromatase inhibitor |
WO2008090327A1 (en) * | 2007-01-22 | 2008-07-31 | Betagenon Ab | New combination for use in the treatment of cancer |
US20080234332A1 (en) * | 2007-03-20 | 2008-09-25 | Xiong Cai | Raf kinase inhibitors containing a zinc binding moiety |
CN101274918A (zh) * | 2007-03-30 | 2008-10-01 | 中国科学院上海药物研究所 | 一类取代五元杂环化合物,其制备方法和医学用途 |
WO2009019445A1 (en) * | 2007-08-03 | 2009-02-12 | Betagenon Ab | Dithiazolidine and thiazolidine derivatives as anticancer agents |
BRPI0818658A2 (pt) | 2007-10-09 | 2015-04-14 | Merck Patent Ges Mit Beschränkter Haftung | Derivados de piridina úteis como ativadores de glicoquinase |
US20110263664A1 (en) * | 2007-11-15 | 2011-10-27 | Musc Foundation For Research Development | Inhibitors of PIM-1 Protein Kinases, Compositions and Methods for Treating Prostate Cancer |
KR100998572B1 (ko) * | 2007-12-14 | 2010-12-07 | 한국생명공학연구원 | 단백질 포스파타제의 활성을 억제하는 페닐아미노티아졸론유도체 또는 이의 약학적으로 허용가능한 염을유효성분으로 함유하는 암 예방 및 치료용 조성물 |
WO2010073011A2 (en) | 2008-12-23 | 2010-07-01 | Betagenon Ab | Compounds useful as medicaments |
WO2010086613A1 (en) | 2009-01-30 | 2010-08-05 | Betagenon Ab | Compounds useful as inhibitors as ampk |
HUE027263T2 (en) | 2009-07-08 | 2016-10-28 | Baltic Bio Ab | 1,2,4-thiazolidin-3-one derivatives and their use in the treatment of cancer |
WO2011079036A1 (en) * | 2009-12-22 | 2011-06-30 | The Translational Genomics Research Institute | Benzamide derivatives |
WO2012118935A1 (en) | 2011-03-03 | 2012-09-07 | Proteotech Inc | Compounds for the treatment of neurodegenerative diseases |
US8722670B2 (en) * | 2011-09-30 | 2014-05-13 | Bristol-Myers Squibb Company | Selective NR2B antagonists |
WO2013108026A1 (en) | 2012-01-17 | 2013-07-25 | Baltic Bio Ab | Thiadiazolone derivatives useful in the treatment of diabetes |
CN104059060B (zh) * | 2014-05-30 | 2017-08-01 | 西安交通大学 | 一种5‑(1h‑吲哚‑3‑亚甲基)‑1,3‑噻唑烷‑4‑酮类衍生物及其合成方法和应用 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3345374A (en) * | 1962-09-04 | 1967-10-03 | Bayer Ag | Certain oxathiazole and dithiazole derivatives |
US3671537A (en) * | 1969-06-05 | 1972-06-20 | Gyogyszerkutato Intezet | Certain 3-(2,6-dichlorophenyl)-2-iminothiazolidines |
US4103018A (en) * | 1976-10-12 | 1978-07-25 | Schering Corporation | 2-[4-(Polyhalo-2-hydroxy-2-propyl)anilino]-2-oxazolin-4-ones and thiazolin-4-ones corresponding thereto |
HU191408B (en) * | 1984-04-25 | 1987-02-27 | Egis Gyogyszergyar,Hu | Process for preparing new imino-thiazolidine derivatives |
DD246541A1 (de) * | 1986-01-27 | 1987-06-10 | Univ Halle Wittenberg | Verfahren zur herstellung von 5-arylidenthiazolidin-4-onen |
DD270072A1 (de) * | 1988-03-14 | 1989-07-19 | Univ Halle Wittenberg | Verfahren zur herstellung von 5-aryliden- hoch 2-thiazolin-4-onen |
US6353006B1 (en) * | 1999-01-14 | 2002-03-05 | Bayer Corporation | Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents |
AU2003282980A1 (en) * | 2002-10-23 | 2004-05-13 | Beyond Genomics, Inc. | 4-alkenylthiazoles comprising epoxide functionality, and methods of use thereof |
WO2005082363A1 (en) * | 2004-02-20 | 2005-09-09 | Board Of Regents, The University Of Texas System | Thiazolone compounds for treatment of cancer |
MXPA06012504A (es) * | 2004-04-30 | 2006-12-15 | Schering Corp | Moduladores del receptor neuropeptido. |
CN1984909A (zh) * | 2004-07-01 | 2007-06-20 | 霍夫曼-拉罗奇有限公司 | 噻唑啉酮未取代的喹啉 |
MX2007001539A (es) * | 2004-08-10 | 2007-04-23 | Exelisis Inc | Compuestos heterociclicos como agentes farmaceuticos. |
KR100890533B1 (ko) * | 2004-10-14 | 2009-03-27 | 에프. 호프만-라 로슈 아게 | Cdk1 저해제로서의 퀴나졸리닐메틸렌 티아졸리논 |
CN100525929C (zh) * | 2005-04-20 | 2009-08-12 | 郭文礼 | 喷水枪出水控制装置 |
CA2614098A1 (en) * | 2005-07-04 | 2007-01-11 | Dr. Reddy's Laboratories Ltd. | Thiazoles derivatives as ampk activator |
-
2006
- 2006-07-21 EA EA200800302A patent/EA200800302A1/ru unknown
- 2006-07-21 AU AU2006271383A patent/AU2006271383A1/en not_active Abandoned
- 2006-07-21 KR KR1020087001175A patent/KR20080032096A/ko not_active Application Discontinuation
- 2006-07-21 AU AU2006271375A patent/AU2006271375A1/en not_active Abandoned
- 2006-07-21 EP EP06765072A patent/EP1906956A2/en not_active Withdrawn
- 2006-07-21 CA CA002615752A patent/CA2615752A1/en not_active Abandoned
- 2006-07-21 EA EA200800303A patent/EA200800303A1/ru unknown
- 2006-07-21 EP EP06765059A patent/EP1906955A2/en not_active Withdrawn
- 2006-07-21 CA CA002614327A patent/CA2614327A1/en not_active Abandoned
- 2006-07-21 WO PCT/GB2006/002730 patent/WO2007010273A2/en active Application Filing
- 2006-07-21 US US11/989,029 patent/US20090156644A1/en not_active Abandoned
- 2006-07-21 KR KR1020087001174A patent/KR20080034436A/ko not_active Application Discontinuation
- 2006-07-21 US US11/989,001 patent/US20090136472A1/en not_active Abandoned
- 2006-07-21 WO PCT/GB2006/002743 patent/WO2007010281A2/en active Application Filing
- 2006-07-21 JP JP2008522062A patent/JP2009501775A/ja not_active Withdrawn
- 2006-07-21 JP JP2008522065A patent/JP2009501776A/ja not_active Withdrawn
-
2007
- 2007-12-10 IL IL188031A patent/IL188031A0/en unknown
- 2007-12-11 NO NO20076333A patent/NO20076333L/no not_active Application Discontinuation
- 2007-12-13 NO NO20076420A patent/NO20076420L/no not_active Application Discontinuation
- 2007-12-16 IL IL188163A patent/IL188163A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
NO20076333L (no) | 2008-04-01 |
WO2007010281A2 (en) | 2007-01-25 |
US20090156644A1 (en) | 2009-06-18 |
CA2615752A1 (en) | 2007-01-25 |
WO2007010281A3 (en) | 2007-06-07 |
IL188163A0 (en) | 2008-03-20 |
KR20080032096A (ko) | 2008-04-14 |
EP1906956A2 (en) | 2008-04-09 |
KR20080034436A (ko) | 2008-04-21 |
JP2009501776A (ja) | 2009-01-22 |
EP1906955A2 (en) | 2008-04-09 |
AU2006271383A1 (en) | 2007-01-25 |
AU2006271375A2 (en) | 2007-01-25 |
WO2007010273A2 (en) | 2007-01-25 |
IL188031A0 (en) | 2011-08-01 |
EA200800303A1 (ru) | 2008-10-30 |
AU2006271375A1 (en) | 2007-01-25 |
CA2614327A1 (en) | 2007-01-25 |
EA200800302A1 (ru) | 2008-08-29 |
WO2007010273A3 (en) | 2007-05-10 |
NO20076420L (no) | 2008-04-09 |
US20090136472A1 (en) | 2009-05-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP2009501775A (ja) | 癌治療におけるチアゾール誘導体およびアナログの使用 | |
JP5982281B2 (ja) | 医薬として有用な化合物 | |
WO2008090356A1 (en) | Thiazolidinone derivatives useful in the treatment of cancer and disorders caused by excess adiposity | |
TWI609015B (zh) | 5-Hydroxyindan derivatives containing heterocyclic rings and uses thereof | |
WO2010086613A1 (en) | Compounds useful as inhibitors as ampk | |
US20220204468A1 (en) | Dp antagonist | |
WO2008090327A1 (en) | New combination for use in the treatment of cancer | |
WO2008065409A2 (en) | Combination for use in the treatment of cancer, comprising tamoxifen or an aromatase inhibitor | |
EP3259256B1 (en) | Compounds and methods for inducing browning of white adipose tissue | |
JP2018009019A (ja) | Kcnq2〜5チャネル関連疾患の予防および/または治療剤 | |
RU2435763C2 (ru) | Ингибиторы тирозинфосфатазы белка человека и способы применения | |
MX2008000972A (en) | Use of thiazole derivatives and analogues in the treatment of cancer | |
EP3027605B1 (en) | Novel indazole compounds and a process for the preparation thereof | |
RU2263669C2 (ru) | Замещенные 8,8a-дигидро-3ah-индено [1,2-d] тиазолы, способ их получения и их применение в качестве лекарственных средств | |
BRPI0613624A2 (pt) | uso de um composto ou um sal ou solvato farmaceuticamente aceitável, ou um derivado farmaceuticamente funcional do mesmo, composto ou um sal ou solvato farmaceuticamente aceitável, ou um derivado funcional do mesmo, formulação farmacêutica, produto combinado, e, métodos de varredura para inibidores de proliferação celular induzida por ácido graxo livre, e para co-estimuladores de proliferação celular induzida por ácido graxo livre | |
MX2008000973A (en) | Use of thiazole derivatives and analogues in disorders caused by free fatty acids | |
ES2232425T3 (es) | Tiazol-2-iliden-aminas policiclicas, procedimiento para su preparacion y su utilizacion como medicamentos. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20090721 |
|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20090721 |
|
A761 | Written withdrawal of application |
Free format text: JAPANESE INTERMEDIATE CODE: A761 Effective date: 20100226 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A821 Effective date: 20100226 |