JP2009155332A - Sunscreen cosmetic - Google Patents
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- JP2009155332A JP2009155332A JP2009003670A JP2009003670A JP2009155332A JP 2009155332 A JP2009155332 A JP 2009155332A JP 2009003670 A JP2009003670 A JP 2009003670A JP 2009003670 A JP2009003670 A JP 2009003670A JP 2009155332 A JP2009155332 A JP 2009155332A
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本発明は、使用性と透明性に優れ、さらに優れた紫外線遮蔽効果を有する日焼け止め化粧料に関する。 The present invention relates to a sunscreen cosmetic that is excellent in usability and transparency and further has an excellent ultraviolet shielding effect.
日焼け止め化粧料は大きくは有機紫外線吸収剤を配合した化粧料と無機紫外線遮蔽剤を配合した化粧料に分けられる。有機紫外線吸収剤は主に透明〜半透明の液体や油分や水分に溶解する固体であるため化粧料に配合した場合に透明性が高く、違和感のない塗布膜となるが、肌に吸収されるため安全性が懸念されていた。一方、無機紫外線遮蔽剤は主に平均粒子径０．１μｍ以下の微粒子金属酸化物であり、肌表面で紫外線を遮蔽するため安全性が比較的高い。しかしながら屈折率が高いため透明性が低く、また肌へ塗布した際にきしみやざらつき等が生じることがあった。これらのことから、使用性と透明性に優れ、さらに紫外線遮蔽効果と安全性の高い日焼け止め化粧料が望まれていた。 Sunscreen cosmetics can be broadly divided into cosmetics containing organic UV absorbers and cosmetics containing inorganic UV screening agents. Organic UV absorbers are mainly transparent to translucent liquids, solids that dissolve in oils and moisture, so when blended in cosmetics, it becomes a highly transparent and comfortable coating film, but is absorbed by the skin. Therefore, safety was a concern. On the other hand, the inorganic ultraviolet shielding agent is mainly a fine particle metal oxide having an average particle diameter of 0.1 μm or less, and is relatively high in safety because it shields ultraviolet rays on the skin surface. However, since the refractive index is high, the transparency is low, and when applied to the skin, squeaks and roughness may occur. For these reasons, sunscreen cosmetics that are excellent in usability and transparency, and have a high UV shielding effect and high safety have been desired.
無機紫外線遮蔽剤の日焼け止め化粧料中における分散性を上げることによって、より強い紫外線遮蔽効果を得ることが可能となる。この、無機紫外線遮蔽剤の分散を上げることによって、紫外線遮蔽効果をより有効に引き出す技術としては例えば、製品中に分散剤を配合する、粉体表面を無機物または有機物で表面処理するなどの方法が良く知られている。かかる方法は無機紫外線遮蔽剤粉体と油分または水分との濡れ性を制御して分散を上げるものであり、分散効果はさほど高くなく、さらに経時的に凝集するという問題があった。またビーズミル、サンドグラインダーミルなどの湿式ミルと呼ばれる機器で予め油分と粉体を強制的に高分散させる方法が提案されており、一定の分散効果は得られているが一時的な分散効果に過ぎず、やはり経時的に凝集するという問題があった。(例えば特許文献１、特許文献２、特許文献３参照) By increasing the dispersibility of the inorganic ultraviolet shielding agent in the sunscreen cosmetic, it is possible to obtain a stronger ultraviolet shielding effect. Examples of techniques for more effectively drawing out the ultraviolet shielding effect by increasing the dispersion of the inorganic ultraviolet shielding agent include, for example, a method of blending a dispersant in a product and surface treatment of the powder surface with an inorganic or organic substance. Well known. This method increases the dispersion by controlling the wettability between the inorganic ultraviolet shielding powder and the oil or moisture, and has a problem that the dispersion effect is not so high and further aggregates with time. In addition, a method for forcibly and highly dispersing oil and powder in a device called a wet mill such as a bead mill or a sand grinder mill has been proposed in advance, and a certain dispersion effect has been obtained, but only a temporary dispersion effect. However, there was also a problem of aggregation over time. (For example, see Patent Document 1, Patent Document 2, and Patent Document 3)
無機紫外線遮蔽剤の凝集を防止する目的で予め板状または球状の粉末と無機紫外線遮蔽材とを複合化して配合する方法が提案されている（例えば特許文献４、特許文献５参照）。かかる複合化粒子を用いて所望の紫外線遮蔽効果を得るためには大量に配合することが必要となるため、結果的に使用性の悪化や安定性の悪化を招くという問題があった。 In order to prevent aggregation of the inorganic ultraviolet shielding agent, a method in which a plate-like or spherical powder and an inorganic ultraviolet shielding material are combined in advance and blended has been proposed (for example, see Patent Document 4 and Patent Document 5). In order to obtain a desired ultraviolet ray shielding effect using such composite particles, it is necessary to add a large amount, and as a result, there is a problem that the usability and the stability are deteriorated.
一方、板状ヒドロキシアパタイトを化粧料に配合することで密着性、延展性が向上することやさらにはスティック化粧料に配合することで粉末が沈降せず、優れた品質のスティック化粧料が得られることが知られている。(特許文献６、特許文献７、特許文献８参照) On the other hand, adhesiveness and spreadability are improved by blending plate-like hydroxyapatite into cosmetics, and even when blended into stick cosmetics, powder does not settle, and excellent quality stick cosmetics are obtained. It is known. (See Patent Document 6, Patent Document 7, and Patent Document 8)
本発明は、上記事情に鑑みてなされたもので、無機紫外線遮蔽剤を使用することで安全性を保ちながら、使用性および透明性に優れ、優れた紫外線遮蔽効果を有する日焼け止め化粧料を提供することを目的とする。 The present invention has been made in view of the above circumstances, and provides a sunscreen cosmetic that is excellent in usability and transparency and has an excellent ultraviolet shielding effect while maintaining safety by using an inorganic ultraviolet shielding agent. The purpose is to do.
本発明はヒドロキシアパタイト粒子の平均粒径が１〜１００μｍで、比表面積が１〜１００ｍ2／ｇである板状ヒドロキシアパタイトおよび無機紫外線遮蔽剤を配合することを特徴とする日焼け止め化粧料を提供する。 The present invention provides a sunscreen cosmetic comprising a hydroxyapatite particle having an average particle size of 1 to 100 μm and a specific surface area of 1 to 100 m 2 / g, and a plate-like hydroxyapatite and an inorganic ultraviolet shielding agent. To do.
本発明の日焼け止め化粧料は、好適には板状ヒドロキシアパタイト、無機紫外線遮蔽剤および油性成分を機械力により高分散させて分散体を得、得られた分散体を他の成分と配合することにより製造されるものである。 The sunscreen cosmetic of the present invention is preferably obtained by dispersing a plate-like hydroxyapatite, an inorganic ultraviolet shielding agent and an oily component with high mechanical force to obtain a dispersion, and blending the obtained dispersion with other components. It is manufactured by.
本発明の日焼け止め化粧料は、より好適には板状ヒドロキシアパタイトを親水性高分子と混合し、該混合物を噴霧乾燥して調製される加圧崩壊性球状粉末とした板状ヒドロキシアパタイトが配合されたものである。 The sunscreen cosmetic of the present invention is more preferably blended with plate-like hydroxyapatite which is prepared by mixing plate-like hydroxyapatite with a hydrophilic polymer and spray-drying the mixture to form a pressure-disintegrating spherical powder. It has been done.
本発明の日焼け止め化粧料は、無機紫外線遮蔽剤を使用することで安全性を保ちながら、透明性並びに紫外線遮蔽効果に優れたものである。本発明の日焼け止め化粧料はまた、肌への密着性並びに使用性に優れたものである。 The sunscreen cosmetic of the present invention is excellent in transparency and ultraviolet shielding effect while maintaining safety by using an inorganic ultraviolet shielding agent. The sunscreen cosmetic of the present invention is also excellent in adhesion to the skin and usability.
本発明において用いられる板状ヒドロキシアパタイトはＣａ１０（ＰＯ４）６（ＯＨ）２またはＣａ１０−Ｚ（ＨＰＯ４）６−Ｚ（ＯＨ）２ｎＨ２Ｏの化学構造を有するものである。板状ヒドロキシアパタイトの平均粒径は１〜１００μｍであるものを用いるが、好ましくは５〜５０μｍ、より好ましくは１０〜３０μｍである。また比表面積は１〜１００ｍ2／ｇ、好ましくは２０〜９０ｍ２／ｇ、より好ましくは４０〜８０ｍ２／ｇのものが用いられる。本発明において「板状」とは、外観の全体形状の如何にかかわらず、平たいものを意味する。板状ヒドロキシアパタイトの構造としては特に制限はなく薄片状、薄板状、鱗片状、葉片状、雲母状、箔状等のものが例示される。板状面についても特に制限はなく、正方形、長方形、平行四辺形、楕円形、円形、不定形等を含み、またこの板状面の表面には凹凸が存在していても良い。具体的には長辺長さと厚みの比（長辺長さ／厚み）が、２〜２００程度のものが好適に用いられる。 Plate hydroxyapatite used in the present invention are those having a Ca 10 (PO 4) 6 ( OH) 2 or Ca 10-Z (HPO 4) 6-Z (OH) 2n H 2 O for chemical structures. The plate-like hydroxyapatite has an average particle diameter of 1 to 100 μm, preferably 5 to 50 μm, more preferably 10 to 30 μm. The specific surface area is 1 to 100 m 2 / g, preferably 20 to 90 m 2 / g, more preferably 40 to 80 m 2 / g. In the present invention, the “plate shape” means a flat shape regardless of the overall shape of the appearance. The structure of the plate-like hydroxyapatite is not particularly limited, and examples thereof include a flaky shape, a thin plate shape, a scale shape, a leaf piece shape, a mica shape, and a foil shape. The plate-like surface is not particularly limited, and includes a square, a rectangle, a parallelogram, an ellipse, a circle, an indeterminate shape, and the like, and irregularities may exist on the surface of the plate-like surface. Specifically, a material having a ratio of long side length to thickness (long side length / thickness) of about 2 to 200 is preferably used.
本発明において用いられる板状ヒドロキシアパタイトは例えば特開平１１−２４０８１９に記載の方法にて調製してもよく、また市販されている板状ヒドロキシアパタイトを用いてもよい。市販品としては、板状ＨＡＰ、板状ＨＡＰ-ＳＣ（太平化学産業製）などが例示される。 The plate-like hydroxyapatite used in the present invention may be prepared, for example, by the method described in JP-A No. 11-240819, or a commercially available plate-like hydroxyapatite may be used. Examples of commercially available products include plate-like HAP, plate-like HAP-SC (manufactured by Taihei Chemical Industry), and the like.
本発明の板状形状ヒドロキシアパタイトの配合量は特に制限されることはないが、日焼け止め化粧料の０．０１〜１０重量％が好ましく、より好ましくは、０．１〜５重量％である。０．０１重量％未満では、無機紫外線散乱剤の分散助剤としての効果が十分で無く、１０重量％以上では、処方中での無機紫外線散乱剤の配合量が制限される為適切でない。 Although the compounding quantity of the plate-shaped hydroxyapatite of this invention is not restrict | limited in particular, 0.01 to 10 weight% of sunscreen cosmetics is preferable, More preferably, it is 0.1 to 5 weight%. If it is less than 0.01% by weight, the effect of the inorganic ultraviolet scattering agent as a dispersion aid is not sufficient, and if it is 10% by weight or more, the blending amount of the inorganic ultraviolet scattering agent in the formulation is limited.
本発明において用いられる無機紫外線遮蔽剤としては、通常日焼け止め化粧料に配合されるものを特に限定なく用いることができ、酸化チタン、酸化亜鉛、酸化セリウムなどが例示される。無機紫外線遮蔽剤としては入手可能な種々の粒子径、形状のものを目的に応じて選択すればよい。例えば、酸化チタンであれば粒状、針状、紡錘状、板状、薄片状等の形状のものを、酸化亜鉛であれば球状または板状の六方晶系のものを、酸化セリウムであれば、球状のものを適宜用いることができる。また、同一物質の異なる粒子径や形状のものを組み合わせて用いても、２以上の物質を任意に組み合わせて用いても良い。 As the inorganic ultraviolet shielding agent used in the present invention, those usually blended in sunscreen cosmetics can be used without particular limitation, and examples thereof include titanium oxide, zinc oxide, and cerium oxide. What is necessary is just to select the thing of the various particle diameter and shape which can be obtained as an inorganic ultraviolet shielding agent according to the objective. For example, titanium oxide is granular, needle-like, spindle-shaped, plate-like, flake-like, etc., zinc oxide is spherical or plate-like hexagonal, and cerium oxide is A spherical thing can be used suitably. Further, the same substances having different particle sizes and shapes may be used in combination, or two or more substances may be used in arbitrary combination.
無機紫外線遮蔽剤は、その一次粒子の平均粒子径が１ｎｍ〜１００ｎｍ、より好ましくは５〜５０ｎｍのものが好適に用いられる。 As the inorganic ultraviolet shielding agent, those having an average primary particle diameter of 1 nm to 100 nm, more preferably 5 to 50 nm are suitably used.
無機紫外線遮蔽剤の一次粒子の平均粒子径が１００ｎｍより大きくなると、粒子の可視光に対する散乱が大きくなるため、可視光の透過性、即ち透明性が低下する。また、１ｎｍより小さくなると紫外線防御効果が低下し望ましくない。 When the average particle diameter of the primary particles of the inorganic ultraviolet shielding agent is larger than 100 nm, the scattering of the particles with respect to visible light increases, so that the transmittance of visible light, that is, transparency is lowered. On the other hand, if it is smaller than 1 nm, the ultraviolet protection effect is lowered, which is not desirable.
これらの無機紫外線遮蔽剤は微細粒子径であり、その表面活性を低下させるため、シリカ、水酸化アルミニウムなどにて表面が被覆されているものが好適に用いられる。 These inorganic ultraviolet shielding agents have a fine particle diameter, and those whose surface is coated with silica, aluminum hydroxide or the like are preferably used in order to reduce the surface activity.
更に無機紫外線遮蔽剤の油性成分への分散性を向上させるため、その表面の一部または全部を疎水化処理剤にて処理したものを好ましく用いることができる。疎水化表面処理剤としては、シリコーン処理剤、脂肪酸、脂肪酸石鹸、脂肪酸エステル等が挙げられる。シリコーン処理剤としては、例えば、メチルハイドロジェンポリシロキサン、ジメチルポリシロキサン、メチルフェニルポリシロキサンなどの各種のシリコーンオイルや、メチルトリメトキシシラン、エチルトリメトキシシラン、ヘキシルトリメトキシシラン、オクチルトリメトキシシランなどの各種のアルキルシランや、トリフルオロメチルエチルトリメトキシシラン、ヘプタデカフルオロデシルトリメトキシシランなどの各種のフルオロアルキルシランなどが挙げられる。脂肪酸としては、例えば、パルミチン酸、イソステアリン酸、ステアリン酸、ラウリン酸、ミリスチン酸、ベヘニン酸、オレイン酸、ロジン酸、１２―ヒドロキシステアリン酸等が挙げられる。脂肪酸石鹸としては、例えば、ステアリン酸アルミニウム、ステアリン酸カルシウム、１２―ヒドロキシステアリン酸アルミニウム等が挙げられる。脂肪酸エステルとしては、デキストリン脂肪酸エステル、コレステロール脂肪酸エステル、ショ糖脂肪酸エステル、デンプン脂肪酸エステル等が挙げられる。これらはいずれも一般的に化粧料の調製の際の無機紫外線遮蔽剤の疎水化処理に用いられるものであり、特に限定されるものではないが、メチルポリシロキサン処理、メチルハイドロジェンポリシロキサン処理が好ましく用いられる。 Furthermore, in order to improve the dispersibility of the inorganic ultraviolet shielding agent in the oil component, it is possible to preferably use a part or all of the surface treated with a hydrophobizing agent. Examples of the hydrophobizing surface treatment agent include silicone treatment agents, fatty acids, fatty acid soaps, and fatty acid esters. Examples of the silicone treating agent include various silicone oils such as methyl hydrogen polysiloxane, dimethyl polysiloxane, and methylphenyl polysiloxane, methyltrimethoxysilane, ethyltrimethoxysilane, hexyltrimethoxysilane, octyltrimethoxysilane, and the like. And various fluoroalkylsilanes such as trifluoromethylethyltrimethoxysilane and heptadecafluorodecyltrimethoxysilane. Examples of the fatty acid include palmitic acid, isostearic acid, stearic acid, lauric acid, myristic acid, behenic acid, oleic acid, rosin acid, 12-hydroxystearic acid and the like. Examples of the fatty acid soap include aluminum stearate, calcium stearate, and 12-hydroxyaluminum stearate. Examples of the fatty acid ester include dextrin fatty acid ester, cholesterol fatty acid ester, sucrose fatty acid ester, starch fatty acid ester and the like. All of these are generally used for the hydrophobic treatment of inorganic UV screening agents in the preparation of cosmetics, and are not particularly limited, but methylpolysiloxane treatment and methylhydrogenpolysiloxane treatment are not limited. Preferably used.
本発明の日焼け止め化粧料において、無機紫外線遮蔽剤の配合量は、無機紫外線遮蔽剤の種類、所望する紫外線遮蔽性等に基づき適宜設定すればよく、特に限定されないが、日焼け止め化粧料の１〜３０重量％、より好ましくは５〜２０重量％とされる。 In the sunscreen cosmetic of the present invention, the blending amount of the inorganic UV screening agent may be appropriately set based on the type of the inorganic UV screening agent, the desired UV screening, and the like. -30% by weight, more preferably 5-20% by weight.
本発明において好ましくは、無機紫外線遮蔽剤は無機紫外線遮蔽剤と油性成分を機械力により高分散させて得られる分散体として板状ヒドロキシアパタイトおよび化粧料の他の成分と配合される。本発明における好適な一態様においては分散体を調製する際に無機紫外線遮蔽剤、油性成分とともに上記の板状ヒドロキシアパタイトを配合する。 In the present invention, the inorganic ultraviolet shielding agent is preferably blended with plate-like hydroxyapatite and other components of the cosmetic as a dispersion obtained by highly dispersing the inorganic ultraviolet shielding agent and the oil component by mechanical force. In a preferred embodiment of the present invention, the plate-like hydroxyapatite is blended together with the inorganic ultraviolet shielding agent and the oil component when preparing the dispersion.
本発明において「機械力により高分散させ」とは、ボールミル、サンドミル、バケットミル、縦型ビーズミル、横型ビーズミル、ピン付きビーズミル、コロイドミル、アトライター、超高圧型ホモジナイザー、超音波分散機など強力な機械力を有する機器にて分散させることを意味する。予め高分散させることにより無機紫外線遮蔽剤が十分に分散され、十分な紫外線防止効果を得ることができる。 In the present invention, “highly dispersed by mechanical force” means a ball mill, sand mill, bucket mill, vertical bead mill, horizontal bead mill, pin bead mill, colloid mill, attritor, ultra high pressure homogenizer, ultrasonic disperser, etc. It means that it is dispersed by a machine having mechanical power. By carrying out high dispersion in advance, the inorganic ultraviolet shielding agent is sufficiently dispersed, and a sufficient ultraviolet ray preventing effect can be obtained.
本発明の日焼け止め化粧料に用いられる油性成分としては、常温で液状の油類であれば、特に限定されることはなく、たとえば、アボガド油、アルモンド油、オリーブ油、ゴマ油、サザンカ油、サフラワー油、大豆油、ツバキ油、トウモロコシ油、ナタネ油、パーシック油、ヒマシ油、綿実油、落花生油等の植物性液状油；ミンク油、卵黄油等の動物性液状油；液状ラノリン、ホホバ油等の液状ロウ類；流動パラフィン、スクワラン等の液状炭化水素油；エステル油、液状シリコーン油など、一般に化粧料の製造に用いられる油類を単独で、または２種以上を組み合わせて用いることができる。なかでも、揮発性溶剤を好ましく用いることができ、特に、シクロメチコン（４、５、６量体）、メチルトリメチコン、カプリリルトリメチコン、イソドデカン、イソヘキサデカン等の揮発性溶剤が好ましい。 The oil component used in the sunscreen cosmetic of the present invention is not particularly limited as long as it is an oil that is liquid at room temperature. For example, avocado oil, almond oil, olive oil, sesame oil, sasanqua oil, safflower Vegetable liquid oil such as oil, soybean oil, camellia oil, corn oil, rapeseed oil, persic oil, castor oil, cottonseed oil, peanut oil; animal liquid oil such as mink oil, egg yolk oil; liquid lanolin, jojoba oil, etc. Liquid waxes; liquid hydrocarbon oils such as liquid paraffin and squalane; oils generally used in the production of cosmetics such as ester oil and liquid silicone oil can be used alone or in combination of two or more. Among these, volatile solvents can be preferably used, and volatile solvents such as cyclomethicone (4, 5, 6 mer), methyl trimethicone, caprylyl trimethicone, isododecane, and isohexadecane are particularly preferable.
本発明の別の好適な態様においては、板状ヒドロキシアパタイトとして板状ヒドロキシアパタイトと親水性高分子を水中で混合して水スラリー状物を得、これをスプレードライヤーにて噴霧乾燥して得られる加圧崩壊性球状粉末が用いられる。 In another preferred embodiment of the present invention, a plate-like hydroxyapatite and a hydrophilic polymer are mixed in water as a plate-like hydroxyapatite to obtain a water slurry, which is obtained by spray drying with a spray dryer. A pressure disintegrating spherical powder is used.
本発明において用いられる加圧崩壊性球状粉末とは、親水性高分子と板状ヒドロキシアパタイトからなる水スラリー状物をスプレードライヤーにて噴霧乾燥することで得られる球状粉末であり、親水性高分子で被覆された板状ヒドロキシアパタイトが球状に凝集したものである。本明細書において「加圧崩壊性」とは、この凝集粉末が、該粉末を材料とした化粧料の使用時の塗布操作により容易に崩壊することを言う。 The pressure-disintegrating spherical powder used in the present invention is a spherical powder obtained by spray-drying an aqueous slurry of a hydrophilic polymer and plate-like hydroxyapatite with a spray dryer. The plate-like hydroxyapatite coated with is aggregated in a spherical shape. In the present specification, “pressure disintegration” means that the aggregated powder is easily disintegrated by an application operation at the time of using a cosmetic material made of the powder.
本明細書において「親水性高分子」とは、水となじみ、水へ容易に分散する高分子をいう。この条件を満たす限り、水溶性高分子のみならず水不溶性高分子もまた含まれる。 In the present specification, the “hydrophilic polymer” refers to a polymer that is compatible with water and easily dispersed in water. As long as this condition is satisfied, not only water-soluble polymers but also water-insoluble polymers are included.
本発明に記載の加圧崩壊性球状粉末の調製に用いられる親水性高分子としては、特に限定されず、アラビアゴム、トラガカントガム、ガラクタン、グアーガム、カラギーナン、キサンタンガム、ペクチン、寒天、ゼラチン、クインスシード、デキストラン、デキストリン、プルラン、カルボキシメチルデンプン、コラーゲン、カゼイン、セルロース、メチルセルロース、メチルヒドロキシプロピルセルロース、ヒドロキシエチルセルロース、ヒドロキシプロピルセルロース、カルボキシメチルセルロース、カルボキシメチルセルロースナトリウム、アルギン酸ナトリウム、カルボキシビニルポリマー、ヒアルロン酸ナトリウム等の水溶性高分子を挙げることができる。かかる水溶性高分子は単独で用いても良いし、２以上を組み合わせて用いてもよい。また水不溶性高分子としては結晶セルロース末、デンプン末、部分α化デンプン末、シルク末、キトサン末、ポリアクリル酸アルキル、ナイロン末等を挙げられることができる。水不溶性高分子はその粒径が０．０１〜５μｍ、より好ましくは０．１〜１μｍのものを用いるとよい。加圧崩壊性球状粉末を製造する際に、親水性高分子として１以上の水溶性高分子と１以上の水不溶性高分子を組み合わせて用いるのが好ましい。特に好ましい水溶性高分子は、ヒドロキシエチルセルロース単独、カルボキシメチルセルロースナトリウムと結晶セルロースの組合せ、およびキサンタンガムとデンプン末の組合せである。 The hydrophilic polymer used for the preparation of the pressure-disintegrating spherical powder described in the present invention is not particularly limited, and gum arabic, gum tragacanth, galactan, guar gum, carrageenan, xanthan gum, pectin, agar, gelatin, quince seed, Water-soluble dextran, dextrin, pullulan, carboxymethyl starch, collagen, casein, cellulose, methylcellulose, methylhydroxypropylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, carboxymethylcellulose, sodium carboxymethylcellulose, sodium alginate, carboxyvinyl polymer, sodium hyaluronate, etc. Can be mentioned. Such water-soluble polymers may be used alone or in combination of two or more. Examples of the water-insoluble polymer include crystalline cellulose powder, starch powder, partially pregelatinized starch powder, silk powder, chitosan powder, alkyl polyacrylate, and nylon powder. The water-insoluble polymer may have a particle size of 0.01 to 5 μm, more preferably 0.1 to 1 μm. When producing the pressure-disintegrating spherical powder, it is preferable to use a combination of one or more water-soluble polymers and one or more water-insoluble polymers as hydrophilic polymers. Particularly preferred water-soluble polymers are hydroxyethylcellulose alone, a combination of sodium carboxymethylcellulose and crystalline cellulose, and a combination of xanthan gum and starch powder.
本発明に記載の加圧崩壊性球状粉末の製造方法は特に制限は無く、従来公知の方法を用いればよい。例えば、親水性高分子を水に投入し、プロペラミキサー、ホモミキサー、ビーズミルあるいはサンドグラインダーミル等を用いて分散し混合液を得る。ついで、この混合液に板状ヒドロキシアパタイトを投入し、更に分散させスラリー状とする。この水スラリー状物を２流体ノズルあるいはアトマイザーを備えたスプレードライヤーに噴霧し乾燥させればよい。 There is no restriction | limiting in particular in the manufacturing method of the pressure disintegrating spherical powder as described in this invention, What is necessary is just to use a conventionally well-known method. For example, a hydrophilic polymer is put into water and dispersed using a propeller mixer, a homomixer, a bead mill, a sand grinder mill or the like to obtain a mixed solution. Next, plate-like hydroxyapatite is added to this mixed solution and further dispersed to form a slurry. This water slurry may be sprayed and dried on a spray dryer equipped with a two-fluid nozzle or an atomizer.
水スラリー状物を調製するにあたり、板状ヒドロキシアパタイトと親水性高分子の配合比は５０：１〜１：１、より好ましくは３０：１〜５：１とする。水の量は限定的ではないが板状ヒドロキシアパタイトと親水性高分子の合計量の１０〜５００倍、より好ましくは５０〜２００倍とする。 In preparing the water slurry, the mixing ratio of the plate-like hydroxyapatite and the hydrophilic polymer is 50: 1 to 1: 1, more preferably 30: 1 to 5: 1. The amount of water is not limited, but is 10 to 500 times, more preferably 50 to 200 times the total amount of plate-like hydroxyapatite and hydrophilic polymer.
本発明において加圧崩壊性球状粉末は、その凝集粒子の平均粒径が５〜１００μｍ、特に１０〜３０μｍのものが好適に用いられる。加圧崩壊性球状粉末の配合量は、上記板状ヒドロキシアパタイトの配合量と同じく日焼け止め化粧料中０．０１〜１０重量％、より好ましくは０．１〜５重量％である。 In the present invention, as the pressure-disintegrating spherical powder, those having an average particle size of 5 to 100 μm, particularly 10 to 30 μm are preferably used. The blending amount of the pressure-disintegrating spherical powder is 0.01 to 10% by weight, more preferably 0.1 to 5% by weight, in the sunscreen cosmetic, similar to the blending amount of the plate-like hydroxyapatite.
本態様において、加圧崩壊性球状粉末は板状ヒドロキシアパタイトとして日焼け止め化粧料の他の成分とともに上記無機紫外線遮蔽剤の油性成分中の分散体と配合することにより本発明の日焼け止め化粧料に配合される。無機紫外線遮蔽剤の油性成分中の分散体は、板状ヒドロキシアパタイトを同時に高分散させたものであってもよい。板状ヒドロキシアパタイトを加圧崩壊性球状粉末として配合することにより、本願発明の化粧料は高い紫外線遮蔽力とより好適な使用感を達成することができる。 In this embodiment, the pressure-disintegrating spherical powder is added to the sunscreen cosmetic of the present invention by blending with the dispersion in the oily component of the inorganic ultraviolet screening agent together with other components of the sunscreen cosmetic as plate-like hydroxyapatite. Blended. The dispersion in the oily component of the inorganic ultraviolet shielding agent may be one in which plate-like hydroxyapatite is highly dispersed at the same time. By blending plate-like hydroxyapatite as a pressure-disintegrating spherical powder, the cosmetic of the present invention can achieve a high ultraviolet shielding power and a more suitable feeling of use.
本発明の日焼け止め化粧料は、無機紫外線遮蔽剤の油性成分中の分散体と板状ヒドロキシアパタイト、または無機紫外線遮蔽剤と板状ヒドロキシアパタイトの油性成分中の分散体を化粧料のその他の成分へ配合することによって製造することができる。加圧崩壊性球状粉末を用いる場合には、無機紫外線遮蔽剤の油性成分中の分散体、および加圧崩壊性球状粉末を化粧料のその他の成分へ配合する。本発明の日焼け止め化粧料を製造するためのその他の成分としては、通常化粧料へ配合される成分から目的とする剤形や製品形態に応じて適宜選択すればよい。例えば、ワセリン、ラノリン、セレシン、マイクロクリスタリンワックス、カルナウバロウ、キャンデリラロウ、高級脂肪酸、高級アルコールなどの固形・半固形油分，スクワラン、流動パラフィン、エステル油、ジグリセライド、トリグリセライド、シリコーン油、オリーブ油、アボガド油、ミンク油などの流動油分，パーフルオロポリエーテル、パーフルオロデカリン、パーフルオロオクタンなどのフッ素系油剤，水溶性および油溶性ポリマー、界面活性剤、多価アルコール、糖類、シリコーン粉体、金属石けん、レシチン、アミノ酸、コラーゲン、ポリマー、無機及び有機顔料、各種表面処理粉体、タール色素、天然色素など色剤、エタノール、防腐剤、酸化防止剤、色素、増粘剤、ＰＨ調整剤、香料、紫外線吸収剤、保湿剤、血行促進剤、冷感剤、殺菌剤、皮膚賦活剤、水が挙げられる。これらの成分はいずれも従来公知の化粧品の処方に応じて本発明の効果を損なわない範囲内で適宜、選択、配合可能である。 The sunscreen cosmetic of the present invention is a dispersion in an oily component of an inorganic UV screening agent and a plate-like hydroxyapatite, or a dispersion in an oily component of an inorganic UV screening agent and a plate-like hydroxyapatite is another component of the cosmetic. It can be manufactured by blending. When using the pressure-disintegrating spherical powder, the dispersion in the oil component of the inorganic ultraviolet shielding agent and the pressure-disintegrating spherical powder are blended into the other components of the cosmetic. What is necessary is just to select suitably as another component for manufacturing the sunscreen cosmetics of this invention from the components normally mix | blended with cosmetics according to the target dosage form and product form. For example, petroleum jelly, lanolin, ceresin, microcrystalline wax, carnauba wax, candelilla wax, solid and semi-solid oils such as higher fatty acids and higher alcohols, squalane, liquid paraffin, ester oil, diglyceride, triglyceride, silicone oil, olive oil, avocado oil Fluid oils such as mink oil, fluorine-based oils such as perfluoropolyether, perfluorodecalin and perfluorooctane, water-soluble and oil-soluble polymers, surfactants, polyhydric alcohols, saccharides, silicone powder, metal soap, Lecithin, amino acids, collagen, polymers, inorganic and organic pigments, various surface treatment powders, tar dyes, natural dyes and other colorants, ethanol, preservatives, antioxidants, dyes, thickeners, pH adjusters, fragrances, ultraviolet rays Absorbent, moisturizer, blood circulation Agents, cooling agents, disinfectants, skin activators, and the like water. Any of these components can be appropriately selected and blended within a range not impairing the effects of the present invention in accordance with a conventionally known cosmetic formulation.
また本発明の日焼け止め化粧料は、その剤形や製品形態が特に限定されるものではなく、油中水型、水中油型、水分散型等の剤形とすることができる。また製品形態としては、紫外線防止効果を付与したい製品であれば特に限定されるものではなく、化粧下地、日焼け止め、ファンデーションなどが例示される。 Moreover, the sunscreen cosmetics of this invention are not specifically limited in the dosage form and product form, It can be set as dosage forms, such as a water-in-oil type, an oil-in-water type, and a water dispersion type. Moreover, as a product form, if it is a product which wants to provide an ultraviolet-ray prevention effect, it will not specifically limit, A makeup | decoration base | substrate, sunscreen, a foundation, etc. are illustrated.
以下に実施例等を挙げて本発明をさらに詳細に説明するが、本発明はこれら実施例等に何ら制約されるものではない。 Hereinafter, the present invention will be described in more detail with reference to examples, but the present invention is not limited to these examples.
製造実施例１〜２、製造比較例１〜４
［紫外線遮蔽剤（微粒子酸化チタン）の油性成分中の分散体の調製］
下記表１の成分を含有する分散体を下記製法によって調製した。得られた分散体について、下記評価方法により紫外線防止効果について評価した。各製造実施例並びに比較例の処方を表１に、紫外線防止効果の測定結果を図１に示す。
Production Examples 1-2, Production Comparative Examples 1-4
[Preparation of dispersion in oily component of UV screening agent (fine particle titanium oxide)]
Dispersions containing the components shown in Table 1 below were prepared by the following production method. About the obtained dispersion, the ultraviolet-ray prevention effect was evaluated with the following evaluation method. Table 1 shows the prescriptions for each of the production examples and comparative examples, and Fig. 1 shows the measurement results of the ultraviolet ray preventing effect.
**:MZY-303S(テイカ社製)：ジメチコン／メチコンコポリマー被覆
***:KF-6028（信越化学社製）
**: MZY-303S (Taika): Dimethicone / methicone copolymer coating
***: KF-6028 (manufactured by Shin-Etsu Chemical)
＜製法＞
表１に示した各成分の混合物を２００ｍＬ容マヨネーズ瓶に１００ｇ秤量し、ディスパーミキサー（ＬＲ−１型；みづほ工業社製）にて３０００rpm、５分間撹拌した。次いで、φ１．０ｍｍジルコニアビーズ２００ｇを加え、サンドミル（ペイントコンディショナー；レッドデビル社製）により１８０分間分散・破砕処理し、製造実施例および製造比較例の分散体を得た。
<Production method>
100 g of the mixture of each component shown in Table 1 was weighed into a 200 mL mayonnaise bottle and stirred at 3000 rpm for 5 minutes with a disper mixer (LR-1 type; manufactured by Mizuho Kogyo Co., Ltd.). Next, 200 g of φ1.0 mm zirconia beads were added, and dispersion and crushing treatment was performed for 180 minutes with a sand mill (paint conditioner; manufactured by Red Devil) to obtain dispersions of Production Examples and Production Comparative Examples.
＜紫外線防止効果の評価＞
製造実施例１〜２および製造比較例1〜４で得られた分散体とシクロメチコンを２：８の重量比で混合した。混合した分散体希釈液を石英板（70×70mm）に6μmの厚みで塗布し、乾燥後、２８０〜７００nmの透過率を分光光度計（U-3010；日立製作所）にて測定し、紫外線防止効果を紫外線領域の３００ｎｍと可視領域の７００ｎｍとの比率を算出することで評価した。
<Evaluation of UV protection effect>
The dispersions obtained in Production Examples 1-2 and Production Comparative Examples 1-4 and cyclomethicone were mixed at a weight ratio of 2: 8. Apply the mixed dispersion dilution to a quartz plate (70 x 70 mm) with a thickness of 6 μm, and after drying, measure the transmittance at 280 to 700 nm with a spectrophotometer (U-3010; Hitachi, Ltd.) to prevent ultraviolet rays. The effect was evaluated by calculating the ratio of 300 nm in the ultraviolet region and 700 nm in the visible region.
表２から明らかなように、本発明の製造実施例１〜２の板状形状ヒドロキシアパタイトを配合したシリコーン分散物は、可視領域光の透過率は高いが紫外領域光はほとんど透過しない。即ち、透明性が高く紫外線の防御効果に優れたものであった。 As is apparent from Table 2, the silicone dispersion containing the plate-shaped hydroxyapatite of Production Examples 1 and 2 of the present invention has a high visible region light transmittance but hardly transmits the ultraviolet region light. That is, it was highly transparent and excellent in the ultraviolet-ray protective effect.
［加圧崩壊性球状粉末製造実施例］
製造実施例３
結晶セルロース０．４５ｇ、カルボキシメチルセルロースナトリウム０．０５ｇをビーカーに秤量し、１．５Ｌの水を加え、ホモミキサーにて約３０分間分散した。これに平均粒径が２０μｍ、比表面積が５０ｍ2／ｇの板状ヒドロシキアパタイト９.５ｇを加え、ホモミキサーで更に約３０分間分散して水スラリー状とした。この水スラリー状物を２流体スプレーノズルを備えたスプレードライヤーに供給した。このとき、スプレードライヤーの熱風温度を２００℃とし、２流体ノズルのスプレー圧を０．６ＭＰaとした。スプレードライヤーにより乾燥させて、板状ヒドロキシアパタイトを含む加圧崩壊性球状粉末を得た。得られた加圧崩壊性球状粉末粒径のメジアン値は２５μｍであった。なお、製造実施例３〜５において加圧崩壊性球状粉末の粒径（凝集粒径）としては日機装株式会社製マイクロトラックＨＲＡを用い、レーザー回折散乱法にて測定して得られた粒度分布のメジアン値を示す。
[Example of production of pressure disintegrating spherical powder]
Production Example 3
0.45 g of crystalline cellulose and 0.05 g of sodium carboxymethylcellulose were weighed in a beaker, 1.5 L of water was added, and the mixture was dispersed with a homomixer for about 30 minutes. To this was added 9.5 g of plate-like hydroxyapatite having an average particle size of 20 μm and a specific surface area of 50 m 2 / g, and the mixture was further dispersed for about 30 minutes with a homomixer to form a water slurry. This water slurry was supplied to a spray dryer equipped with a two-fluid spray nozzle. At this time, the hot air temperature of the spray dryer was 200 ° C., and the spray pressure of the two-fluid nozzle was 0.6 MPa. It was dried with a spray dryer to obtain a pressure-disintegrating spherical powder containing plate-like hydroxyapatite. The median value of the obtained pressure-disintegrating spherical powder particle size was 25 μm. In Production Examples 3 to 5, as the particle size (aggregated particle size) of the pressure-disintegrating spherical powder, a particle size distribution obtained by measurement by a laser diffraction scattering method using Microtrack HRA manufactured by Nikkiso Co., Ltd. was used. Indicates the median value.
製造実施例４
ヒドロキシエチルセルロース１．０ｇをビーカーに秤量し、１．０Ｌの水を加え、プロペラミキサーにて約３０分間分散した。これに平均粒径が１５μｍ、比表面積が７０ｍ2／ｇの板状ヒドロシキアパタイト９.０ｇを加え、ホモミキサーで更に約３０分間分散して水スラリー状とした。この水スラリー状物を２流体スプレーノズルを備えたスプレードライヤーに供給した。このとき、スプレードライヤーの熱風温度を１８０℃とし、２流体ノズルのスプレー圧を０．８ＭＰaとした。このようにして、板状ヒドロキシアパタイトを含む加圧崩壊性球状粉末を得た。得られた加圧崩壊性球状粉末粒径のメジアン値は２０μｍであった。
Production Example 4
1.0 g of hydroxyethylcellulose was weighed into a beaker, 1.0 L of water was added, and the mixture was dispersed with a propeller mixer for about 30 minutes. To this was added 9.0 g of plate-like hydroxyapatite having an average particle size of 15 μm and a specific surface area of 70 m 2 / g, and the mixture was further dispersed with a homomixer for about 30 minutes to form a water slurry. This water slurry was supplied to a spray dryer equipped with a two-fluid spray nozzle. At this time, the hot air temperature of the spray dryer was 180 ° C., and the spray pressure of the two-fluid nozzle was 0.8 MPa. In this way, a pressure-disintegrating spherical powder containing plate-like hydroxyapatite was obtained. The median value of the obtained pressure-disintegrating spherical powder particle size was 20 μm.
製造実施例５
デンプン末０．５ｇ、キサンタンガム０．８ｇをビーカーに秤量し、１．８Ｌの水を加え、ホモミキサーにて約３０分間分散した。これに平均粒径が２５μｍ、比表面積が４０ｍ2／ｇの板状ヒドロシキアパタイト８.７ｇを加え、ビーズミルで更に約３０分間分散して水スラリー状とした。この水スラリー状物を２流体スプレーノズルを備えたスプレードライヤーに供給した。このとき、スプレードライヤーの熱風温度を２２０℃とし、２流体ノズルのスプレー圧を０．５ＭＰaとした。このようにして、板状ヒドロキシアパタイトを含む加圧崩壊性球状粉末を得た。得られた加圧崩壊性球状粉末粒径のメジアン値は３０μｍであった。
Production Example 5
0.5 g of starch powder and 0.8 g of xanthan gum were weighed in a beaker, 1.8 L of water was added, and the mixture was dispersed with a homomixer for about 30 minutes. To this was added 8.7 g of plate-like hydroxyapatite having an average particle size of 25 μm and a specific surface area of 40 m 2 / g, and the mixture was further dispersed by a bead mill for about 30 minutes to form a water slurry. This water slurry was supplied to a spray dryer equipped with a two-fluid spray nozzle. At this time, the hot air temperature of the spray dryer was 220 ° C., and the spray pressure of the two-fluid nozzle was 0.5 MPa. In this way, a pressure-disintegrating spherical powder containing plate-like hydroxyapatite was obtained. The median value of the pressure disintegrating spherical powder particle size obtained was 30 μm.
実施例１〜２および比較例１〜４
［シェイクウェル型Ｗ／Ｏ型日焼け止め化粧料］
下記表３の組成の油中水型乳化化粧料を下記製法によって調製した。得られた油中水型乳化化粧料について、下記評価方法により透明性、紫外線防止効果、使用性について評価した。透明性の結果を図１に、その他評価結果を表４に示す。
[Shakewell type W / O type sunscreen cosmetics]
A water-in-oil emulsified cosmetic composition having the composition shown in Table 3 below was prepared by the following production method. The obtained water-in-oil emulsified cosmetic was evaluated with respect to transparency, ultraviolet ray prevention effect and usability by the following evaluation methods. The results of transparency are shown in FIG. 1 and other evaluation results are shown in Table 4.
＜製法＞
全体が秤量できる容器に成分（１）〜（１４）を室温にて、均一に混合した。次いで、別の容器に、成分（１５）〜（１７）を室温にて、均一に混合分散した。（１）〜（１４）に（１５）〜（１７）を加え乳化し、シェイクウェル型Ｗ／Ｏ型日焼け止め化粧料を得た。
<Production method>
Components (1) to (14) were uniformly mixed at room temperature in a container capable of being weighed as a whole. Next, components (15) to (17) were uniformly mixed and dispersed in another container at room temperature. (1) to (14) (15) to (17) were added and emulsified to obtain a Shakewell type W / O type sunscreen cosmetic.
＜評価方法：透明性の評価＞
実施例１〜２および比較例１〜４で得られたシェイクウェル型Ｗ／Ｏ型日焼け止め化粧料を石英板（７０×７０ｍｍ）に６μｍの厚みで塗布し、乾燥後の可視光での透過率（４００〜７００ｎｍ）を分光光度計（Ｕ−３０１０；日立製作所）にて測定した。結果を図１に示す。
<Evaluation method: Evaluation of transparency>
Shakewell type W / O type sunscreen cosmetics obtained in Examples 1-2 and Comparative Examples 1-4 were applied to a quartz plate (70 × 70 mm) with a thickness of 6 μm, and transmitted with visible light after drying. The rate (400 to 700 nm) was measured with a spectrophotometer (U-3010; Hitachi, Ltd.). The results are shown in FIG.
＜評価方法：紫外線防止効果の評価＞
実施例１〜２および比較例１〜４で得られたシェイクウェル型Ｗ／Ｏ型日焼け止め化粧料をトランスポアテープ（住友３Ｍ社製）に２ｍｇ／ｃｍ２になるよう均一に塗布し、ＳＰＦ Analyzer UV-1000S(Labsphere社製)にてin-vitro SPF値の測定を行った。結果を表４に示す。
<Evaluation method: Evaluation of UV protection effect>
The shake well type W / O type sunscreen cosmetics obtained in Examples 1 and 2 and Comparative Examples 1 to 4 were uniformly applied to a transpore tape (manufactured by Sumitomo 3M) to 2 mg / cm 2 , and SPF The in-vitro SPF value was measured with Analyzer UV-1000S (Labsphere). The results are shown in Table 4.
＜評価方法：使用性の評価＞
パネラー５名が粉体の平滑感、きしみ、ざらつきなどの粉体の感触について以下に示す１〜５の＜５段階絶対評価＞に基づいて評価を行い、その平均点を算出した。得られた平均点を元に下記＜４段階評価＞にてランク付けした。結果を表４に示す。
<Evaluation method: Evaluation of usability>
Five panelists evaluated the powder texture such as smoothness, squeakiness, and roughness of the powder based on <5 stage absolute evaluation> of 1 to 5 shown below, and the average score was calculated. Based on the average score obtained, ranking was performed according to the following <4 step evaluation>. The results are shown in Table 4.
＜５段階絶対評価＞
１．平滑感などの感触が悪い
２．平滑感などの感触がやや悪い
３．普通
４．平滑感などの感触がややよい
５．平滑感などの感触がよい
<5-level absolute evaluation>
1. 1. The feeling of smoothness is bad. 2. The feeling of smoothness is a little bad. Normal 4. 4. A feeling such as smoothness is slightly good. Good feeling such as smoothness
＜４段階評価＞
（評点）
◎： ４点以上、
○： ３点以上４点未満、
△： ２点以上３点未満、
×： ２点未満
<4-level evaluation>
(Score)
◎: 4 points or more,
○: 3 points or more and less than 4 points
Δ: 2 or more and less than 3
×: Less than 2 points
紫外線防止効果、使用性試験結果
図１および表４から明らかなように実施例１〜２の日焼け止め化粧料は透明性が高く、また比較例１〜４の化粧料に比べ、紫外線防止効果に優れ、更に使用性にも優れたものであった。 As is clear from FIG. 1 and Table 4, the sunscreen cosmetics of Examples 1 and 2 have high transparency, and are superior in UV protection effect and superior in usability compared to the cosmetics of Comparative Examples 1 to 4. It was.
実施例３〜５および比較例５〜８
［シェイクウェル型Ｗ／Ｏ型日焼け止め化粧料］
下記表５の組成の油中水型乳化化粧料を下記製法によって調製した。得られた油中水型乳化化粧料について、上記評価方法と同様に透明性、紫外線防止効果並びに使用性の評価を行った。透明性の結果を図２、その他評価結果を表６に示す。
Examples 3-5 and Comparative Examples 5-8
[Shakewell type W / O type sunscreen cosmetics]
A water-in-oil emulsified cosmetic composition having the composition shown in Table 5 below was prepared by the following production method. About the obtained water-in-oil type emulsified cosmetic, transparency, an ultraviolet-ray prevention effect, and usability were evaluated similarly to the said evaluation method. The results of transparency are shown in FIG. 2 and other evaluation results are shown in Table 6.
<製法>
全体が秤量できる容器に成分（１）〜（１４）を室温にて、均一に混合した。次いで、別の容器に、成分（１５）〜（１７）を室温にて、均一に混合分散した。（１）〜（１４）に（１５）〜（１７）を加え乳化し、シェイクウェル型Ｗ／Ｏ型日焼け止め化粧料を得た。
<Production method>
Components (1) to (14) were uniformly mixed at room temperature in a container capable of being weighed as a whole. Next, components (15) to (17) were uniformly mixed and dispersed in another container at room temperature. (1) to (14) (15) to (17) were added and emulsified to obtain a Shakewell type W / O type sunscreen cosmetic.
紫外線防止効果、使用性試験結果
図２、および表６から明らかなように実施例３〜５の化粧料は、透明性については比較例５〜８の化粧料とほぼ同等であったが、これら比較例に比べて紫外線防止効果に優れ、更に使用性も優れたものであった。 As is apparent from FIG. 2 and Table 6, the cosmetics of Examples 3 to 5 were almost the same as the cosmetics of Comparative Examples 5 to 8 in terms of transparency, but the UV-preventing effect compared to these comparative examples. In addition, the usability was also excellent.
実施例６〜７
［Ｗ／Ｏ乳化型ファンデーション］
[W / O emulsified foundation]
<製法>
油相部（１）〜（７）に予めヘンシェルミキサーにて撹拌混合した粉体部（１０）〜（１４）を加え、撹拌機にて均一に分散した。別の容器に（８）〜（９）を混合した。（１）〜（７）及び（１０）〜（１４）に（８）〜（９）を加え乳化後、室温まで冷却し、目的のＷ／Ｏ乳化型ファンデーションを得た。
<Production method>
The powder parts (10) to (14) previously stirred and mixed with a Henschel mixer were added to the oil phase parts (1) to (7) and dispersed uniformly with a stirrer. (8) to (9) were mixed in another container. (1) to (7) and (10) to (14) were added with (8) to (9) and emulsified, and then cooled to room temperature to obtain the target W / O emulsion type foundation.
<結果>
得られた実施例６のＷ／Ｏ乳化型ファンデーションのin−vitroＳＰＦ値は、３０．５であり、紫外線のダメージから皮膚を守り、皮膚に塗布した場合、べたつかず、化粧持続性に優れたW/O乳化型ファンデーションであった。実施例７の乳化ファンデーションは、in-vitro SPF値が３１．２であり、のびが軽く使用性に優れたＷ／Ｏ乳化型ファンデーションであった。
<Result>
The in-vitro SPF value of the obtained W / O emulsified foundation of Example 6 was 30.5. When the skin was protected from UV damage and applied to the skin, it was not sticky and had excellent makeup durability. / O emulsified foundation. The emulsified foundation of Example 7 was a W / O emulsified foundation having an in-vitro SPF value of 31.2, a light stretch and excellent usability.
実施例８〜９
［化粧下地（Ｗ／Ｏサンスクリーンクリーム）］
＊＊：板状ＨＡＰ（太平化学産業製）
Examples 8-9
[Makeup base (W / O sunscreen cream)]
**: Plate-shaped HAP (manufactured by Taihei Chemical Industry)
<製法>
油相部（１）〜（７）に（８）〜（１０）を加え、撹拌機にて均一に分散した。別の容器に加熱溶解した水相部（１１）〜（１４）を（１）〜（７）および（８）〜（１０）に加え乳化後、室温まで冷却し、目的の化粧下地を得た。
<Production method>
(8) to (10) were added to the oil phase parts (1) to (7) and dispersed uniformly with a stirrer. Water phase parts (11) to (14) dissolved by heating in another container were added to (1) to (7) and (8) to (10) and emulsified, and then cooled to room temperature to obtain the desired makeup base. .
<結果>
得られた実施例８の化粧下地はin-vitro SPF値が、２０．５であり、紫外線のダメージから皮膚を守り、皮膚に塗布した場合、べたつかない、好ましい使用感の化粧下地であった。実施例９の化粧下地は、in-vitro SPF値が２１．８であり、実施例８と同等のＳＰＦ値でありながら、より感触の軽い仕上がりが得られた。
<Result>
The obtained cosmetic base of Example 8 had an in-vitro SPF value of 20.5, and was a cosmetic base having a preferable feeling of use that did not become sticky when applied to the skin while protecting the skin from ultraviolet damage. The makeup base of Example 9 had an in-vitro SPF value of 21.8, and although the SPF value was the same as that of Example 8, a lighter finish was obtained.
実施例１０
［Ｗ／Ｏサンスクリーン乳液］
[W / O sunscreen emulsion]
<製法>
油相部（１）〜（６）に（７）、（８）を加え、撹拌機にて均一に分散し加熱した。別の容器に加熱溶解した水相部（９）〜（１２）を（１）〜（６）および（７）、（８）に加え乳化後、室温まで冷却し、目的のＷ／Ｏサンスクリーン乳液を得た。
<Production method>
(7) and (8) were added to the oil phase parts (1) to (6), and the mixture was uniformly dispersed with a stirrer and heated. Water phase parts (9) to (12) dissolved by heating in another container are added to (1) to (6) and (7) and (8), emulsified, cooled to room temperature, and the desired W / O sunscreen An emulsion was obtained.
<結果>
得られたＷ／Ｏサンスクリーン乳液のin-vitro SPF値は、４０．５であり、紫外線のダメージから皮膚を守り、皮膚に塗布した場合、べたつかず、のびが軽い化粧下地であった。
<Result>
The obtained W / O sunscreen emulsion had an in-vitro SPF value of 40.5. When applied to the skin, it was a non-sticky and lightly spread makeup base when applied to the skin.
実施例１１〜１２
［Ｏ／Ｗサンスクリーンクリーム］
[O / W sunscreen cream]
<製法>
（１）〜（４）を８５℃に加熱溶解し、ついで（５）〜（７）を加え、撹拌機にて均一に分散した。別の容器に８５℃に加熱溶解した（８）〜（１２）を（１）〜（４）および（５）〜（７）に加え乳化後、室温まで冷却し、目的のＯ／Ｗサンスクリーンクリームを得た。
<Production method>
(1) to (4) were heated and dissolved at 85 ° C., then (5) to (7) were added, and the mixture was uniformly dispersed with a stirrer. (8) to (12) dissolved by heating at 85 ° C. in another container is added to (1) to (4) and (5) to (7), emulsified, cooled to room temperature, and the desired O / W sunscreen A cream was obtained.
<結果>
得られた実施例１１のＯ／Ｗサンスクリーンクリームのin-vitro SPF値は、１２．３、実施例１２のin-vitro SPF値は１１．４であった。実施例１１のサンスクリーンクリームは実施例１２と比べて紫外線のダメージからより強く皮膚を守り、皮膚に塗布した場合、べたつかず、のびが軽いサンスクリーンクリームであった。
<Result>
The in-vitro SPF value of the obtained O / W sunscreen cream of Example 11 was 12.3, and the in-vitro SPF value of Example 12 was 11.4. The sunscreen cream of Example 11 was a sunscreen cream that protected the skin from UV damage more strongly than Example 12, and when applied to the skin, it was non-sticky and lightly spreads.
実施例１３〜１４
[Ｗ／Ｏサンスクリーンクリーム]
[W / O sunscreen cream]
<製法>
油相部（１）〜（８）を加え、撹拌機にて均一に分散した。別の容器に加熱溶解した水相部（９）〜（１２）を（１）〜（８）に加え乳化後、室温まで冷却し、目的のＷ／Ｏサンスクリーンクリームを得た。
<Production method>
Oil phase parts (1) to (8) were added and dispersed uniformly with a stirrer. The aqueous phase parts (9) to (12) dissolved by heating in another container were added to (1) to (8) and emulsified, and then cooled to room temperature to obtain the desired W / O sunscreen cream.
<結果>
得られた実施例１３のＷ／Ｏサンスクリーンクリームのin-vitro SPF値は、２１．８であり、紫外線のダメージから皮膚を守り、皮膚に塗布した場合、べたつかないＷ／Ｏサンスクリーンクリームであった。実施例１４のＷ／Ｏサンスクリーンクリームのin-vitro SPF値は２３であり、実施例１３とほぼ同じＳＰＦ値をもち、より軽やかな感触であった。
<Result>
The resulting W / O sunscreen cream of Example 13 has an in-vitro SPF value of 21.8, which is a non-sticky W / O sunscreen cream when applied to the skin, protecting the skin from UV damage. there were. The in-vitro SPF value of the W / O sunscreen cream of Example 14 was 23, almost the same SPF value as in Example 13, and a lighter feel.
Claims (5)
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| JP2007334140A Division JP2009155249A (en) | 2007-12-26 | 2007-12-26 | Sunscreen cosmetic |
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| US20110280943A1 (en) * | 2009-11-10 | 2011-11-17 | Zahra Mansouri | Sunscreen Compositions Comprising Uniform, Rigid, Spherical, Nanoporous Calcium Phosphate Particles and Methods of Making and Using the Same |
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| US9095510B2 (en) | 2009-11-10 | 2015-08-04 | Laboratory Skin Care, Inc. | Sunscreen compositions comprising uniform, rigid, spherical, nanoporous calcium phosphate particles and methods of making and using the same |
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| US10123950B2 (en) | 2009-11-10 | 2018-11-13 | Laboratory Skin Care, Inc. | Sunscreen compositions comprising uniform, rigid, spherical, nanoporous calcium phosphate particles and methods of making and using the same |
| US10857077B2 (en) | 2009-11-10 | 2020-12-08 | Laboratory Skin Care, Inc. | Sunscreen compositions comprising uniform, rigid, spherical, nanoporous calcium phosphate particles and methods of making and using the same |
| JP2012077081A (en) * | 2010-09-30 | 2012-04-19 | Easthill Co Ltd | Ultraviolet blocking composite dispersion and method for producing the same |
| JP2013133306A (en) * | 2011-12-27 | 2013-07-08 | Fancl Corp | Sunscreen cosmetic |
| JP2013177328A (en) * | 2012-02-28 | 2013-09-09 | Daito Kasei Kogyo Kk | Hyaluronic acid-coated powder and method for producing the same, and cosmetic compounded therewith |
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