WO2018124287A1

WO2018124287A1 - Oil-in-water emulsion composition

Info

Publication number: WO2018124287A1
Application number: PCT/JP2017/047295
Authority: WO
Inventors: 浩一岸田
Original assignee: 花王株式会社
Priority date: 2016-12-28
Filing date: 2017-12-28
Publication date: 2018-07-05
Also published as: CN110114053A; KR20190101359A; JP2018108994A; JP6757713B2

Abstract

An oil-in-water emulsion composition which contains the following components (A)-(D) and in which the content mass ratio [(A)/(B)] of component (A) with respect to component (B) is 0.06-18. (A) Polyoxyethylene alkyl ether or polyoxyethylene alkenyl ether in which the number of carbon atoms of the alkyl group or alkenyl group is 20-24 and the average number of added mol of ethylene oxide is 1.5-4; (B) a phospholipid; (C) a hydrophobically treated powder; and (D) water.

Description

Oil-in-water emulsion composition

The present invention relates to an oil-in-water emulsion composition.

In recent years, the importance of sunburn countermeasures in daily life has been pointed out, and even in cosmetics that have a protective effect against ultraviolet rays, an oil-in-water emulsion type sunscreen cosmetic that is easy to use continuously with a refreshing feeling of use It has been developed. In these oil-in-water emulsified cosmetics, an ultraviolet scattering agent (hydrophobized metal oxide powder) is blended in order to enhance the ultraviolet protection effect (see Patent Documents 1 and 2).

However, when a large amount of metal oxide powder such as zinc oxide and titanium oxide, which are ultraviolet scattering agents, is blended, not only powder aggregation and sedimentation occur over time, but also stability over time such as viscosity reduction, emulsification separation and precipitation. There was a problem of lowering.

On the other hand, in Patent Document 3, an ultraviolet scattering agent (hydrophobized metal oxide powder) is prepared using polyoxyethylene alkyl ether or polyoxyethylene alkenyl ether whose carbon chain length and number of moles of ethylene oxide added are within a certain range. A stably formulated sunscreen cosmetic is disclosed. These sunscreen cosmetics have excellent low-temperature stability by forming the soft layered structure (multi-lamellar vesicle structure) by the presence of the compound at the interface between the aqueous phase and the oil phase, elongation on the skin, The stickiness is also good, the sticky feeling and squeaky feeling are suppressed, and the moisturizing effect is also high.

(Patent Document 1) JP 2006-8796 JP (Patent Document 2) JP 2005-272389 JP (Patent Document 3) JP 2014-114274 JP

The present invention includes the following components (A) to (D), wherein the mass ratio [(A) / (B)] of component (A) to component (B) is 0.06 or more and 18 or less An emulsified composition is provided.
(A) Polyoxyethylene alkyl ether or polyoxyethylene alkenyl ether having an alkyl group or alkenyl group having 20 to 24 carbon atoms and an average addition mole number of ethylene oxide of 1.5 to 4 (B) Phospholipid (C ) Hydrophobized powder (D) Water

Detailed Description of the Invention

In the technique described in Patent Document 3, there is room for improvement in the stability of the composition, such as partial emulsification failure at high temperatures, and a decrease in viscosity when high shear force is applied.

Therefore, the present invention relates to an oil-in-water emulsion composition that stably contains a hydrophobized powder, is excellent in stability of an emulsification system when stored at high temperature or when shearing force is applied, and is excellent in use feeling such as freshness. .

As a result of various studies, the present inventor formulated a hydrophobized powder by using a specific polyoxyethylene alkyl ether or the like used in the technique described in Patent Document 3 and a phospholipid in a specific ratio. The present invention was completed by finding that the oil-in-water emulsion composition thus obtained can be greatly improved in stability at high temperatures and resistance to shearing force (hereinafter referred to as “shear resistance”).

[Component (A): Polyoxyethylene alkyl (or alkenyl) ether having a specific range of carbon chain length / EO addition moles]
The polyoxyethylene alkyl ether or polyoxyethylene alkenyl ether of component (A) used in the present invention has an alkyl group or an alkenyl group having 20 to 24 carbon atoms and an average added mole number of ethylene oxide of 1.5 to 4 Is.

The alkyl group or alkenyl group of component (A) may be linear or branched, and is preferably a linear or branched alkyl group, more preferably from the viewpoint of forming a lamellar structure at the oil phase interface. It is a linear alkyl group. The number of carbon atoms of the alkyl group or alkenyl group is 20 or more, preferably 21 or more, from the viewpoint of forming a lamellar structure at the oil phase interface and improving high temperature stability (emulsification stability) and shear resistance. Moreover, from the viewpoint of stably dissolving in the oil phase, it is 24 or less, preferably 23 or less. From these viewpoints, the alkyl group or alkenyl group preferably has 22 carbon atoms, and among them, an alkyl group having 22 carbon atoms (that is, a behenyl group) is more preferable.

The average number of moles of ethylene oxide added in component (A) is 1.5 or more from the viewpoint of lowering the crystallinity and facilitating dissolution in the oil phase. From the viewpoint of improving (emulsion stability) and shear resistance, it is 4 or less, preferably 3 or less, more preferably 2.5 or less. The generally available polyoxyethylene alkyl ether or polyoxyethylene alkenyl ether is a mixture having a very wide distribution centering on a desired degree of polymerization in terms of the number of moles of ethylene oxide added. It is important that the number is within the above range.

As component (A), polyoxyethylene (2) aralkyl ether, polyoxyethylene (3) aralkyl ether, polyoxyethylene (4) aralkyl ether, polyoxyethylene (2) behenyl ether, polyoxyethylene (3) behenyl Examples include ether, polyoxyethylene (4) behenyl ether, polyoxyethylene (2) carnerville ether, polyoxyethylene (3) carnerville ether, polyoxyethylene (4) carnerville ether, and preferably polyoxyethylene (2) Behenyl ether, polyoxyethylene (3) behenyl ether, polyoxyethylene (4) behenyl ether are mentioned. In addition, as long as the average added mole number of the polyoxyethylene alkyl ether to be used is in the above range, it is possible to use other than those exemplified polyoxyethylene alkyl ether in combination.

The content of component (A) in the oil-in-water emulsion composition of the present invention is preferably from the viewpoint of facilitating the formation of a lamellar structure at the oil phase interface, improving the shear resistance, and improving the fresh feeling of use. 0.05% by mass or more, more preferably 0.10% by mass or more, further preferably 0.12% by mass or more, more preferably 0.16% by mass or more, further preferably 0.5% by mass or more, further preferably 0.8% by mass or more, and preferably 5% by mass or less, more preferably 3% by mass or less, further preferably 2% by mass or less, further preferably 1.82% by mass or less, still more preferably 1.5% by mass or less, and further preferably 1.2% by mass or less. The specific content range of component (A) is preferably 0.05 to 5% by mass, more preferably 0.10 to 3% by mass, still more preferably 0.12 to 2% by mass, still more preferably 0.16 to 1.82% by mass, and still more preferably Is 0.5 to 1.5 mass%, more preferably 0.8 to 1.2 mass%.

[Component (B): Phospholipid]
As the phospholipid of component (B), the phosphatidylcholine content is 60% by mass or more, and further 62% by mass or more from the viewpoint of improving high-temperature stability and shear resistance, suppressing stickiness, accustoming to the skin, and improving makeup. In addition, it is preferably 65% by mass or more. Moreover, what has a phosphatidylcholine content of 98 mass% or less is preferable. Examples of phospholipid components other than phosphatidylcholine include phosphatidic acid, phosphatidylserine, phosphatidylethanolamine, phosphatidylinositol, and phosphatidylglycerol.

The phospholipid used in the present invention may be a natural product extracted and purified from animals or plants, or may be chemically synthesized, or may be subjected to processing such as hydrogenation or hydroxylation. . As a natural product, lecithin which is an extract / purified product from soybean or egg yolk is preferable from the viewpoint of improving stability over time and reducing skin irritation, and more preferably hydrogenated or hydroxylated.

Specifically, soybean hydrogenated lecithin and egg yolk lecithin hydrogenated are preferably mentioned.

The content of phosphatidylcholine in the phospholipid can be analyzed by a method using thin layer chromatography (TLC), high performance liquid chromatography (HPLC), Iatroscan (manufactured by Yatron). For example, an organic solvent containing phospholipids described in JP-A-2001-186898 is spotted on TLC, developed in chloroform: methanol: acetic acid = 65: 25: 10, sprayed with 50% by mass of ethanol sulfate, and heated. A method of analyzing phospholipids with a post densitometer is mentioned. In addition to the above method, any method may be used as long as it can measure and calculate the content and content of phosphatidylcholine contained in the phospholipid.

Phospholipids containing 60% by mass or more of phosphatidylcholine include Coatsome NC-21 (hydrogenated soybean lecithin; manufactured by NOF Corporation), Resinol S-10E, Resinol S-10EX (hydrogenated soybean lecithin; Nikko Chemicals) And Phospholipid PCSH70 (hydrogenated soybean lecithin; manufactured by Nippon Seika Co., Ltd.).

The content of the component (B) in the oil-in-water emulsion composition of the present invention is preferably 0.05% by mass or more, more preferably 0.10% by mass or more from the viewpoint of improving high-temperature stability, shear resistance, and usability. More preferably, it is 0.12% by mass or more, more preferably 0.16% by mass or more, further preferably 0.5% by mass or more, further preferably 0.8% by mass or more, and preferably 5% by mass or less, more preferably 3% by mass. Hereinafter, it is further preferably 2% by mass or less, more preferably 1.82% by mass or less, further preferably 1.5% by mass or less, and further preferably 1.2% by mass or less. The specific content range of component (B) is preferably 0.05 to 5% by mass, more preferably 0.10 to 3% by mass, still more preferably 0.12 to 2% by mass, still more preferably 0.16 to 1.82% by mass, and still more preferably Is 0.5 to 1.5 mass%, more preferably 0.8 to 1.2 mass%.

The total content of component (A) and component (B) in the oil-in-water emulsion composition of the present invention is preferably 0.5% by mass or more, more preferably 1.2% by mass, from the viewpoint of improving high-temperature stability and shear resistance. % Or more, more preferably 1.8% by mass or more, and from the viewpoint of improving freshness, it is preferably 6% by mass or less, more preferably 3.5% by mass or less, and still more preferably 2.5% by mass or less. The specific total content range of component (A) and component (B) is preferably 0.5 to 6% by mass, more preferably 1.2 to 3.5% by mass, and still more preferably 1.8 to 2.5% by mass.

In addition, the content ratio [(A) / (B)] of the component (A) to the component (B) is preferably 0.06 or more, more preferably 0.08 or more, from the viewpoint of improving high-temperature stability and shear resistance. Preferably, it is 0.10 or more, more preferably 0.5 or more, and from the viewpoint of obtaining a fresh feeling of use, it is preferably 18 or less, more preferably 14 or less, still more preferably 10 or less, and even more preferably 3 or less. The content ratio [(A) / (B)] of the component (A) to the specific component (B) is preferably 0.06 to 18, more preferably 0.08 to 14, still more preferably 0.10 to 10, more preferably 0.5-3.

[Component (C): Hydrophobized powder]
The powder used for the hydrophobized powder of component (C) is not particularly limited as long as it is used in the pharmaceutical, cosmetic and food fields, zinc oxide, titanium oxide, cerium oxide, iron oxide, chromium oxide, Carbon Black, Titanium Black, Bentonite, Kaolin, Mica, Sericite, Talc, Gunjo, Gunjo Pink, Red 202, Red 220, Red 226, Blue 404, Yellow 401, Polyethylene powder, Polystyrene powder, Poly Examples include methyl methacrylate powder, nylon powder, silicone powder, and cellulose powder. From the viewpoint of improving emulsification stability and UV protection effect, metal oxide powder is preferable, and zinc oxide, titanium oxide, cerium oxide, iron oxide, and the like. More preferably, it contains at least one selected from chromium oxide, zinc oxide, titanium oxide and acid It is further preferred to include one or more selected from iron. In particular, when used for skin color correction, it is preferable to use iron oxide that can be adjusted to a color close to skin color, and when used for sunscreen, it has a high ultraviolet light scattering effect, from zinc oxide, titanium oxide, and cerium oxide. It is preferable to use one or more selected ones, and by using these together, it is possible to achieve both skin color correction and sunscreen effects.

As zinc oxide powder, for example, FINEX-25, FINEX-50, FINEX-75 (manufactured by Sakai Chemical), MZ500 series, MZ700 series (manufactured by Teika), ZnO-350 (manufactured by Sumitomo Osaka Cement Co., Ltd.), etc. are commercially available. ing. As titanium oxide powder, TTO-55 series, TTO-51 series (Ishihara Sangyo Co., Ltd.), JR series, JA series (Taika Co., Ltd.), etc. are commercially available. As the iron oxide powder, LL-100P, R-516P, BL-100P (manufactured by Titanium Industry Co., Ltd.) and the like are commercially available. The cerium oxide includes high purity cerium sold by Nikki or Seimi Chemical.

The average particle size of the powder used for the hydrophobized powder of component (C) is from the emulsified particle size of the oil-in-water emulsion composition from the viewpoint of improving emulsification stability by including the hydrophobized powder in the oil phase. Is preferably 28 μm or less, more preferably 23 μm or less, still more preferably 18 μm or less, and preferably from 0.01 μm or more, more preferably 0.012 μm or more, from the viewpoint of suppressing powder agglomeration, More preferably, it is 0.015 μm or more. The specific average particle diameter is preferably 0.01 to 28 μm, more preferably 0.012 to 23 μm, and still more preferably 0.015 to 18 μm. The oil-in-water emulsion composition of the present invention is more effective when a powder having a color pigment level is encapsulated in the oil phase. The average particle size was measured by arithmetic average of the particle sizes of 20 arbitrary powders in an arbitrary field of view in a transmission electron micrograph. For powders other than a spherical shape such as a rod shape, a spindle shape, a needle shape, a flake shape, and an indefinite shape, the arithmetic average of the major axes was regarded as the average particle diameter.

Examples of the shape of the powder used in the present invention include a spherical shape, a rod shape, a spindle shape, a needle shape, a flake shape, and an indeterminate shape, but any shape having an average particle diameter in the above range may be used. it can.

The hydrophobizing treatment to the powder is not particularly limited, and various hydrophobizing treatments such as fluorine compound treatment, silicone treatment, silicone resin treatment, pendant treatment, silane coupling agent treatment, titanate coupling agent treatment, Oil agent treatment, acylamino acid metal salt treatment, polyacrylic acid treatment, metal soap treatment, crystalline cellulose treatment, inorganic compound treatment, plasma treatment, mechanochemical treatment, silane compound treatment, silazane compound treatment and the like can be used.

Among these, from the viewpoint of improving the dispersibility of the powder and improving the high temperature stability and the low temperature stability, hydrophobic treatment using silicone or silicone resin, methyl hydrogen polysiloxane or the following general formula (1) Hydrophobic treatment using methylhydrogenpolysiloxane / dimethylpolysiloxane copolymer, hydrophobic treatment using silane compound or silazane compound, hydrophobization treatment using titanate coupling agent and acylamino acid metal salt 1 type or 2 types or more of hydrophobizing treatments selected from the hydrophobizing treatments used are preferable, hydrophobizing treatment using methylhydrogenpolysiloxane, hydrophobizing treatment using silane compound or silazane compound, titanate coupling Hydrophobic treatment using an agent and hydrophobic treatment using an acylamino acid metal salt One or more hydrophobic treatment is more preferable.

As the hydrophobizing treatment using the silicone or the silicone resin, as described in Japanese Patent No. 3187440, the powder is at least one of a silicone compound (excluding a silane compound) made of an organopolysiloxane and a silicone resin. An example is a method of coating a powder with silicon oxide by coating in a non-gas phase state with at least a seed and then firing at a temperature of 600 to 950 ° C. in an oxygen-containing atmosphere.

The silane compound or silazane compound is preferably a silane compound or silazane compound having an alkyl group or fluoroalkyl group having 1 to 20 carbon atoms and having reactivity with an inorganic oxide. Specifically, the following general formula (2 ) Or a silazane compound represented by the general formula (3), and one or more of these can be used.

RR ¹ _n SiX _3-n (2)

(N is an integer of 0 or 1, R is a linear or branched alkyl group or fluoroalkyl group having 1 to 20 carbon atoms, R ¹ is an alkyl group having 1 to 6 carbon atoms, and X is Represents a halogen atom or an alkoxy group.)

R ² R ³ R ⁴ SiNHSiR ⁵ R ⁶ R ⁷ (3)

(R ² to R ⁷ each independently represents a linear or branched alkyl group or fluoroalkyl group having 1 to 20 carbon atoms.)

Specific silane compounds include hexyltrimethoxysilane, octyltrimethoxysilane, decyltrimethoxysilane, octadecyltrimethoxysilane, octyltriethoxysilane, trifluoropropyltrimethoxysilane, heptadecafluorodecyltrimethoxysilane, and the like. It is done. Of these, octyltriethoxysilane and octyltrimethoxysilane are preferred. As the silazane compound, hexamethyldisilazane is preferable. The silane compound or silazane compound is characterized in that it is easy to treat uniformly, is easy to supply and is inexpensive in cost, and cosmetics formulated with powders hydrophobized with these compounds have characteristics such as dispersibility. Since it is excellent, it is preferable.

As the hydrophobization treatment using the silane compound or silazane compound, the silane compound or silazane compound and powder are mixed in an organic solvent such as n-hexane, cyclohexane or lower alcohol, and finely pulverized in some cases. Examples of the method include a method in which the surface is removed by heating or reduced pressure, and a chemical reaction is preferably performed on the surface of the powder by a reactive group of the silane compound or silazane compound, such as a heat treatment at 80 to 250 ° C.

In addition, as described in JP-A-2007-326902, there is a method in which a powder is coated with a specific polysiloxane compound, and then an alkylalkoxysilane is hydrophobized in water.

As the hydrophobizing treatment using the titanate coupling agent, as described in JP-A-1-131282, isopropyl triisostearoyl titanate, isopropyl tris (dioctyl pyrophosphate) titanate in an aqueous powder dispersion is used. , Titanate such as isopropyltri (N-aminoethyl-aminoethyl) titanate, isopropyltridecylbenzenesulfonyl titanate, etc., stirring at high speed and mixing, optionally washing with water and drying, titanate coupling to powder Examples of the method include spraying the agent, mixing with high shear stirring, and optionally pulverizing. When mixing the powder with the titanate coupling agent, it is preferable to add a small amount of an aqueous solution of metal chloride such as zinc chloride or aluminum chloride, thereby causing the reaction to occur rapidly and uniformly over the entire surface of the powder. be able to.

Hydrophobing treatment using the acylamino acid metal salt may be carried out with a solvent such as water, alcohols (ethanol, isopropyl alcohol, isobutanol, etc.), polar solvents (acetone, ethyl acetate, butyl acetate, etc.) or various mixed solvents. An example is a method in which the N-acylamino acid metal salt is dissolved or dispersed, the solution is stirred and mixed with the powder, and then the solvent is removed.

N-acylamino acid metal salts include N-hexanoyl aspartic acid (glutamic acid), N-oleyl aspartic acid (glutamic acid), N-lauroyl aspartic acid (glutamic acid), N-myristoyl aspartic acid (glutamic acid), N-palmitoyl Examples thereof include metal salts such as aspartic acid (glutamic acid), N-stearoyl aspartic acid (glutamic acid), and N-linolenoyl aspartic acid (glutamic acid). Note that the notation such as “N-hexanoyl aspartic acid (glutamic acid)” means both N-hexanoyl aspartic acid and N-hexanoyl glutamic acid. Examples of the metal salt include sodium salt, potassium salt, calcium salt, magnesium salt and the like.

The coating amount of the hydrophobizing agent on the powder is based on the total amount of powder used from the viewpoint that the surface of the powder is uniformly coated with the surface treating agent and the hydrophobizing agent does not aggregate or precipitate on the powder surface. The amount is preferably 1% by mass or more, more preferably 1.5% by mass or more, and preferably 10% by mass or less, more preferably 5% by mass or less. The specific coating amount is preferably 1 to 10% by mass, more preferably 1.5 to 5% by mass.

The content of component (C) in the oil-in-water emulsion composition of the present invention is preferably 0.1% by mass or more, more preferably 1% by mass or more, and still more preferably, from the viewpoint of improving the UV protection effect and emulsion stability. Is 5% by mass or more, preferably 30% by mass or less, more preferably 20% by mass or less, and still more preferably 15% by mass or less. The specific range of component (C) is preferably 0.1 to 30% by mass, more preferably 1 to 20% by mass, and still more preferably 5 to 15% by mass.

[Component (D): Water]
The water content in the oil-in-water emulsion composition of the present invention is preferably 40% by mass or more from the viewpoint of improving the fresh feel and forming an oil-in-water emulsion composition excellent in high temperature stability and shear resistance. More preferably, it is 45% by mass or more, preferably 80% by mass or less, more preferably 75% by mass or less. The specific content range of water is preferably 40 to 80% by mass, more preferably 45 to 75% by mass.

[Component (E): Liquid oil]
The liquid oil of component (E) is an oil having fluidity at 25 ° C. under 1013.25 hPa, and this includes liquid organic ultraviolet absorbers and oils used in ordinary cosmetics. In the present invention, in order to enhance the ultraviolet protection effect, it is preferable to contain a liquid organic ultraviolet absorber.

Liquid organic ultraviolet absorbers include 2-methoxyhexyl paramethoxycinnamate, 2-ethoxyethyl paramethoxycinnamate, isopropyl dimethoxycinnamate and diisopropyl cinnamate ester, methyl bis (trimethyl trimethoxycinnamate) From the group consisting of (siloxy) silylisopentyl, paradimethylamino acid amyl benzoate, paradimethylamino acid 2-ethylhexyl benzoate, ethylene glycol salicylate, 2-ethylhexyl salicylate, benzyl salicylate, homomenthyl salicylate, octocrylene, dimethicodiethylbenzalmalonate The 1 type (s) or 2 or more types selected can be mentioned. Among these, from the viewpoint of improving UV protection effect, emulsified state, high temperature stability and low temperature stability, paramethoxycinnamate 2-ethylhexyl, salicylate 2-ethylhexyl, salicylate homomenthyl, octocrylene and dimethicodiethylbenzalmalonate It is preferable that 1 type or 2 or more types selected from these are included, and it is more preferable that 1 type or 2 or more types selected from 2-ethylhexyl paramethoxycinnamate, octocrylene, and dimethicodiethylbenzalmalonate are included. It is more preferable to contain 2-ethylhexyl paramethoxycinnamate.

The oil agent other than the organic ultraviolet absorber contained in the liquid oil is not particularly limited as long as it is liquid in an environment of 1013.25 hPa and 25 ° C. Specifically, hydrocarbon oils such as α-olefin oligomer, liquid isoparaffin, liquid paraffin, squalane; glyceryl trioctanoate, avocado oil, olive oil, sesame oil, rice bran oil, safflower oil, soybean oil, corn oil, rapeseed oil, Triglycerides such as castor oil, cottonseed oil, mink oil; fatty acids such as oleic acid and isostearic acid; isopropyl myristate, butyl myristate, isopropyl palmitate, ethyl oleate, ethyl linoleate, isopropyl linoleate, cetyl caprylate, lauric acid Hexyl, decyl myristate, decyl oleate, oleyl oleate, isostearyl laurate, isotridecyl myristate, isocetyl myristate, isostearyl myristate, octyldodecyl myristate Octyl palmitate, isocetyl palmitate, isostearyl palmitate, propylene glycol dioleate, isodecyl oleate, isopropyl isostearate, cetyl 2-ethylhexanoate, stearyl 2-ethylhexanoate, propylene glycol dicaprate, propylene glycol dioleate, Ester oils such as glyceryl tri-2-ethylhexanoate, glyceryl tri (capryl / caprate), isononyl isononanoate, diisopropyl sebacate, propylene glycol isostearate; branched or 2-octyldodecanol, isostearyl alcohol, oleyl alcohol, etc. Examples thereof include unsaturated higher alcohols; dimethylpolysiloxane. Of these, octyldodecyl myristate, isocetyl myristate, cetyl 2-ethylhexanoate, glyceryl tri-2-ethylhexanoate, glyceryl tri (capryl-caprate), isononyl isononanoate, diisopropyl sebacate, propylene isostearate One or more selected from glycol, neopentyl glycol dicaprate, isohexadecane, squalane and hydrogenated polyisobutene.

The content of the component (E) in the oil-in-water emulsion composition of the present invention is preferably 5% by mass or more from the viewpoint of improving a fresh feeling of use and improving the emulsified state, high temperature stability and low temperature stability. More preferably, it is 8 mass% or more, More preferably, it is 10 mass% or more, Preferably it is 25 mass% or less, More preferably, it is 20 mass% or less, More preferably, it is 18 mass% or less. The specific content range of component (E) is preferably 5 to 25% by mass, more preferably 8 to 20% by mass, still more preferably 10 to 20% by mass, and further preferably 10 to 18% by mass.

In addition, from the viewpoint of improving the fresh feeling of use while reducing the liquid oil content, and improving the high temperature stability and the UV protection effect, the content ratio of the liquid organic UV absorber in the total component (E) is: It is preferably 0.3 or more, more preferably 0.5 or more, still more preferably 0.6 or more, and even more preferably 0.7 or more.

[Component (F): UV absorber solid at 25 ° C]
The oil-in-water emulsion composition of the present invention preferably further contains a UV absorber solid at 25 ° C. as component (F) in order to enhance the UV protection effect. The ultraviolet absorber solid at 25 ° C. used in the present invention is not particularly limited as long as it can be blended in cosmetics, quasi drugs, and pharmaceuticals.

Specific examples of component (F) include dimethoxybenzylidenedioxoimidazolidinepropionic acid 2-ethylhexyl, diethylaminohydroxybenzoylbenzoic acid hexyl ester, 2,4-bis [[4- (2-ethylhexyloxy) -2-hydroxy]- Phenyl] -6- (4-methoxyphenyl) -1,3,5-triazine, 2,4,6-tris [4- (2-ethylhexyloxycarbonyl) anilino] -1,3,5-triazine and 4- One type or two or more types selected from the group consisting of tert-butyl-4′-methoxydibenzoylmethane can be mentioned.

Among these, diethylaminohydroxybenzoyl benzoic acid hexyl ester, 2,4-bis [[4- (2-ethylhexyloxy) -2-hydroxy] -phenyl, from the viewpoint of improving UV protection effect, high temperature stability and shear resistance ] -6- (4-methoxyphenyl) -1,3,5-triazine and 2,4,6-tris [4- (2-ethylhexyloxycarbonyl) anilino] -1,3,5-triazine One or two or more selected can be preferably used.

These components (F) are generally commercially available, soft shade DH (dimethoxybenzylidenedioxoimidazolidinepropionate 2-ethylhexyl; manufactured by Ajinomoto Co., Inc.), ubinal Aplus (2- (4-diethylamino-2-hydroxybenzoyl) benzoic acid Acid hexyl ester; manufactured by BASF), Tinosorb S (2,4-bis [[4- (2-ethylhexyloxy) -2-hydroxy] -phenyl] -6- (4-methoxyphenyl) -1,3, 5-triazine (manufactured by BASF), ubinal T-150 (2,4,6-tris [4- (2-ethylhexyloxycarbonyl) anilino] -1,3,5-triazine), parasol 1789 (4-tert- Butyl-4'-methoxydibenzoylmethane; manufactured by Roche).

The content of the component (F) in the oil-in-water emulsion composition of the present invention is preferably 0.5% by mass or more, more preferably 1% by mass from the viewpoint of improving the UV protection effect, high temperature stability and shear resistance. More preferably, it is 1.5% by mass or more, preferably 10% by mass or less, more preferably 7.5% by mass or less, and still more preferably 5% by mass or less. The specific content range of component (F) is preferably 0.5 to 10% by mass, more preferably 0.5 to 7.5% by mass, and still more preferably 0.5 to 5% by mass.

[Component (G): Water-soluble polymer]
The oil-in-water emulsion composition of the present invention preferably further contains a water-soluble polymer as component (G) in order to increase the dispersion stability of the aqueous phase and improve the high temperature and low temperature stability. Examples of the water-soluble polymer used in the present invention include a water-soluble cationic polymer, an anionic polymer, a nonionic polymer, and an amphoteric polymer or a bipolar polymer.

Specific examples of the cationic polymer include hydroxyethyl cellulose (polyquaternium-10) having a chloride O- [2-hydroxy-3- (trimethylammonio) propyl] group, vinylpyrrolidone-dimethylaminomethylethyl methacrylate copolymer Examples thereof include diethyl diethyl sulfate (polyquaternium-11), methylvinylimidazolium chloride / vinylpyrrolidone copolymer, and the like.

Specific examples of the anionic polymer include carboxyvinyl polymer, carboxymethyl cellulose, carrageenan, xanthan gum, polystyrene sulfonate, agar, gatch gum, caraya gum, pectin, alginate salt, acrylic acid / alkyl methacrylate copolymer, (acrylic acid (Na / acryloyldimethyltaurine Na) copolymer, polyacrylamide, (acryloyldimethyltaurine ammonium / VP) copolymer, (acryloyldimethyltaurine ammonium methacrylate, Behenes-25) crosspolymer, (hydroxyethyl acrylate / acryloyldimethyltaurine Na) copolymer, ( Acrylamide / ammonium acrylate) copolymer, (Na acrylate / acryloyl dimethyl taurine / dimethyl acrylamide) Ross polymer, polyacrylate-13, polyacrylate crosspolymer-6, alkali metal salt of poly (acrylic acid), hyaluronic acid or an alkali metal salt thereof.

Specific examples of the nonionic polymer include cellulose ether (hydroxybutylmethylcellulose, hydroxypropylcellulose, hydroxypropylmethylcellulose, ethylhydroxyethylcellulose, hydroxyethylcellulose, etc.), propylene glycol alginate, poly (ethylene oxide), polyvinyl alcohol, polyvinyl Examples include pyrrolidone, hydroxypropyl guar gum, locust bean gum, amylose, hydroxyethyl amylose, starch and starch derivatives, and mixtures thereof.

Specific examples of the amphoteric polymer or the bipolar polymer include octylacrylamide / acrylate / butylaminoethyl methacrylate copolymer, polyquaternium-47, polyquaternium-43 and the like.

These water-soluble polymers can be used alone or in appropriate combination of two or more. From the viewpoint of improving emulsion stability and facilitating application to various dosage forms, carboxyvinyl polymer, acrylic acid / alkyl methacrylate copolymer, xanthan gum, hydroxypropyl methylcellulose, polyacrylamide, (Na acrylate / acryloyldimethyl) It preferably contains at least one selected from taurine Na) copolymer, (acryloyldimethyltauronium ammonium / VP) copolymer and hyaluronic acid or alkali metal salts thereof, polyacrylamide, (Na acrylate / acryloyldimethyltaurine Na) copolymer, More preferably, it contains one or more selected from (acryloyldimethyltaurate ammonium / VP) copolymer and xanthan gum.

From the above viewpoint, the content of the component (G) in the oil-in-water emulsion composition of the present invention is preferably 0.01% by mass or more, more preferably 0.05% by mass or more, and further preferably 0.1% by mass or more. Further, it is preferably 4% by mass or less, more preferably 2% by mass or less, and further preferably 1.5% by mass or less. The specific content range of component (G) is preferably 0.01 to 4% by mass, more preferably 0.05 to 2% by mass, and still more preferably 0.1 to 1.5% by mass.

[Component (H): C1-C3 saturated monohydric alcohol]
The oil-in-water emulsified composition of the present invention is a monovalent saturated monovalent having 1 to 3 carbon atoms as a component (H) from the viewpoint of a refreshing feeling of use, good elongation at the time of application, and water / sweat resistance. It is preferable to contain alcohol. Examples of the component (H) include methyl alcohol, ethyl alcohol, propyl alcohol, and isopropyl alcohol, which can be used alone or in appropriate combination of two or more. Among these, from the above viewpoint, it is preferable to include one or two selected from ethyl alcohol and isopropyl alcohol, and it is more preferable to include ethyl alcohol.

The content of the component (H) in the oil-in-water emulsion composition of the present invention is not particularly limited, but it has a refreshed feeling of use, good elongation at the time of application, and water / sweat resistance is improved. Therefore, it is preferably 1% by mass or more, more preferably 3% by mass or more, further preferably 5% by mass or more, preferably 20% by mass or less, more preferably 15% by mass or less, and further preferably 12% by mass or less. It is. The specific content range of component (H) is preferably 1 to 20% by mass, more preferably 3 to 15% by mass, and still more preferably 5 to 12% by mass.

[Component (I): Polyhydric alcohol]
The oil-in-water emulsion composition of the present invention preferably further contains a polyhydric alcohol as component (I) in order to improve the moisture retention after coating and the good elongation during coating. Examples of the component (I) include ethylene glycol, diethylene glycol, triethylene glycol, polyethylene glycol (average molecular weight is preferably less than 650), propylene glycol, dipropylene glycol, polypropylene glycol (average molecular weight is preferably less than 650), isoprene glycol, Glycerols such as 1,3-butylene glycol; glycerins such as glycerin, diglycerin, and polyglycerin can be used, and these can be used alone or in combination of two or more.

Among these, from the above viewpoint, it is preferable to contain one or more selected from ethylene glycol, diethylene glycol, propylene glycol, dipropylene glycol, 1,3-butylene glycol, glycerin and diglycerin, More preferably, it contains one or more selected from dipropylene glycol, 1,3-butylene glycol and glycerin.

The content of the component (I) in the oil-in-water emulsion composition of the present invention is preferably 0.1% by mass or more, more preferably 0.5% by mass or more, and more preferably 0.5% by mass or more from the viewpoint of improving the moisturizing property and good elongation during application. The amount is preferably 1% by mass or more, more preferably 12% by mass or less, more preferably 8% by mass or less, still more preferably 5% by mass or less, and further preferably 3% by mass or less. The specific content range is preferably 0.1 to 12% by mass, more preferably 0.5 to 8% by mass, still more preferably 1 to 5% by mass, and still more preferably 1 to 3% by mass.

The average emulsified particle size of the oil-in-water emulsion composition of the present invention is preferably 1 μm or more, preferably 30 μm or less, preferably 25 μm or less from the viewpoint of improving emulsification stability, improving the fresh feeling of use, and uniform coating properties. More preferred is 20 μm or less. Specifically, it is preferably 1 to 30 μm, more preferably 1 to 25 μm, still more preferably 1 to 20 μm. The average particle size of the emulsified particles can be obtained from the number-based average value by repeatedly measuring the particle size of 20 arbitrary particles in an arbitrary field of view in the micrograph.

[Other optional ingredients]
In the oil-in-water emulsion composition of the present invention, in addition to the above components, various surfactants, oily components, silicone compounds, high-grade compounds usually incorporated in cosmetics, as long as the effects of the present invention are not impaired. Alcohol, fluorine compound, resin, thickener, antibacterial preservative, moisturizer, salt, solvent, antioxidant, chelating agent, neutralizer, pH adjuster, insect repellent, bioactive ingredient, antiperspirant, Various raw materials usually used in cosmetics such as perfumes and extracts of various animals and plants can be contained. In addition, each of these agents is not limited to the use as each agent, diverted as other uses according to the purpose, for example, using an antiperspirant as a fragrance, or as a combination with other uses, for example, It can be used as an effect as an antiperspirant and a fragrance.

The oil-in-water emulsified cosmetic of the present invention can contain a surfactant for the purpose of adjusting the emulsion stability. The surfactant is not particularly limited, and includes nonionic surfactants, anionic surfactants, cationic surfactants, amphoteric surfactants, natural surfactants, polyether-modified silicones, siloxane derivatives, and the like. Any of a silicone-containing surfactant, a surfactant containing a perfluoroalkyl group, and the like can be used, and one or more of these can be used.

Of these surfactants, nonionic surfactants, polyether-modified silicones, and silicone-containing surfactants are preferred. Specifically, sorbitan monoisosotearate, dimethicone copolyol, polyoxyethylene hydrogenated castor oil (40EO), polyoxyethylene castor oil (40EO), polyoxyethylene sorbitan monolaurate (20EO), polyoxyethylene monostearate (20EO), polyoxyethylene sorbitan oleate (20EO), polyoxyethylene (7) lauryl And ether, PEG-7 trimethylolpropane coconut oil alkyl ether, and the like.

In the oil-in-water emulsified cosmetic of the present invention, the emulsion stability is good without using the above-mentioned surfactant together, and when a large amount of the surfactant is blended, a sticky feeling derived from the surfactant may occur. Therefore, the preferable content is preferably 3% by mass or less, more preferably 1.5% by mass or less, and still more preferably 0.5% by mass or less with respect to the total amount of the oil-in-water emulsion composition. As a specific range, 0 to 3% by mass is preferable, 0 to 1.5% by mass is more preferable, and 0 to 0.5% by mass is still more preferable.

[Use]
There is no restriction | limiting in particular as an application of the oil-in-water type emulsion composition of this invention, It can use suitably for cosmetics, a pharmaceutical, a quasi-drug, etc. The oil-in-water emulsified composition of the present invention is a skin external preparation of the type that is retained on the skin (including the scalp) without being washed away, and more preferably the skin excluding the scalp, more preferably from the viewpoint of excellent moisture occlusive effect. Can be used by applying to any of the face, body, limbs and the like. Moreover, since it is excellent in stability even if it contains an ultraviolet absorber or an ultraviolet scattering agent, it is preferably applied to sunscreen applications, in particular, sunscreens, suntans, cosmetic base cosmetics, foundations having ultraviolet protective ability, and the like.

(Drug type)
The dosage form of the oil-in-water emulsion composition of the present invention can be applied to liquids, emulsions, creams, pastes, solids, multilayers, etc., and also to sheet agents, spray agents, and mousse agents. Applicable.

〔Production method〕
The oil-in-water emulsion composition of the present invention can be produced by a predetermined procedure depending on the form. For example, the oil-in-water emulsion composition of the present invention can be produced by a method including a step of mixing together various components including components (A) to (D) and optionally components (E) to (I). . Specifically, the method for producing the oil-in-water emulsion composition of the present invention includes:
An oil phase containing component (A), component (B), component (C), optionally component (E), component (F) and other oil-soluble optional components, preferably at 50 to 90 ° C., more preferably Is a step 1a of heating and stirring at 55 to 85 ° C .;
The aqueous phase containing component (D), optionally component (G), component (I), component (H) and other water-soluble optional components is preferably 50 to 90 ° C., more preferably 55 to 85 ° C. And heating and stirring in step 2a,
Step 3a may be included in which the preparation of Step 1a and the preparation of Step 2a are mixed and emulsified.

In step 3a, the preparation of step 2a is cooled to 15-40 ° C., preferably 20-30 ° C. and the preparation of step 1a is maintained above 40 ° C., preferably 50-70 ° C. While stirring the product, it is preferable to add the preparation of Step 1a and uniformly stir and mix to emulsify. Thereby, at the same time when the oil phase is introduced into the aqueous phase, the component (A) can easily form a lamellar structure at the interface of the oil phase, and a stable oil-in-water emulsion composition can be obtained.

In order to improve the dispersibility of the component (C) in the oil phase, it is preferable to include a step of dispersing the component (C) in advance before adding the component (C) to the oil phase. In particular,
The oil phase containing component (A) and component (B), and optionally component (E), component (F) and other oil-soluble optional components, is preferably 50 to 90 ° C., more preferably 55 to 85 ° C. Step 1b of heating and stirring at
Step 2b for uniformly dispersing component (C);
Add the preparation of step 2b to the preparation of step 1b, and heat and stir preferably at 50 to 90 ° C., more preferably 55 to 85 ° C. and step (3b), component (D) if necessary, component (G), component Step 4b of heating and stirring the aqueous phase containing (I), component (H) and other water-soluble optional components, preferably at 50 to 90 ° C., more preferably 55 to 85 ° C .;
Step 5b may be included to mix and emulsify the preparation of Step 3b and the preparation of Step 4b.

In step 3b, the preparation of step 4b is cooled to 15-40 ° C., preferably 20-30 ° C., and the preparation of step 3b is maintained above 40 ° C., preferably 50-70 ° C. While stirring the product, it is preferable to add the preparation of Step 3b and uniformly stir and mix to emulsify. Thereby, at the same time when the oil phase is introduced into the aqueous phase, the component (A) can easily form a lamellar structure at the interface of the oil phase, and a stable oil-in-water emulsion composition can be obtained.

With respect to the embodiments described above, preferred embodiments of the present invention will be further disclosed below.

<1> Oil-in-water emulsification comprising the following components (A) to (D), wherein the mass ratio of component (A) to component (B) [(A) / (B)] is 0.06 or more and 18 or less Composition.
(A) Polyoxyethylene alkyl ether or polyoxyethylene alkenyl ether having an alkyl group or alkenyl group having 20 to 24 carbon atoms and an average addition mole number of ethylene oxide of 1.5 to 4 (B) Phospholipid (C ) Hydrophobized powder (D) Water

<2> The oil-in-water emulsion composition according to <1>, wherein the alkyl group or alkenyl group of component (A) is preferably a linear or branched alkyl group, more preferably a linear alkyl group. object.

<3> The oil-in-water emulsion composition according to <1> or <2>, wherein the carbon number of the alkyl group or alkenyl group in the component (A) is preferably 21 or more and 23 or less, more preferably 22.

<4> The oil-in-water emulsion composition according to any one of <1> to <3>, wherein the average added mole number of ethylene oxide in component (A) is preferably 3 or less, more preferably 2.5 or less. .

<5> The content of the component (A) is preferably 0.05% by mass or more, more preferably 0.10% by mass or more, further preferably 0.12% by mass or more, further preferably 0.16% by mass or more, and further preferably 0.5% by mass or more. More preferably, it is 0.8% by mass or more, preferably 5% by mass or less, more preferably 3% by mass or less, still more preferably 2% by mass or less, further preferably 1.82% by mass or less, and further preferably 1.5% by mass or less. The oil-in-water emulsion composition according to any one of <1> to <4>, more preferably 1.2% by mass or less.

<6> The phosphatidylcholine content in the phospholipid of component (B) is preferably 60% by mass or more, more preferably 62% by mass or more, still more preferably 65% by mass or more, and 98% by mass or less. The oil-in-water emulsion composition according to any one of> to <5>.

<7> The oil-in-water emulsion composition according to any one of <1> to <6>, wherein the component (B) is preferably selected from soybean lecithin hydrogenated product and egg yolk lecithin hydrogenated product.

<8> The content of component (B) is preferably 0.05% by mass or more, more preferably 0.10% by mass or more, further preferably 0.12% by mass or more, further preferably 0.16% by mass or more, and further preferably 0.5% by mass or more. More preferably, it is 0.8% by mass or more, preferably 5% by mass or less, more preferably 3% by mass or less, further preferably 2% by mass or less, still more preferably 1.82% by mass or less, and further preferably 1.5% by mass. The oil-in-water emulsion composition according to any one of <1> to <7>, further preferably 1.2% by mass or less.

<9> The total content of component (A) and component (B) is preferably 0.5% by mass or more, more preferably 1.2% by mass or more, still more preferably 1.8% by mass or more, and preferably 6% by mass. The oil-in-water emulsion composition according to any one of <1> to <8>, more preferably 3.5% by mass or less, and still more preferably 2.5% by mass or less.

<10> The mass ratio [(A) / (B)] of the component (A) to the component (B) is preferably 0.06 or more, more preferably 0.08 or more, further preferably 0.10 or more, more preferably 0.5 or more. The oil-in-water emulsion composition according to any one of <1> to <9>, which is preferably 18 or less, more preferably 14 or less, still more preferably 10 or less, and still more preferably 3 or less.

<11> The powder used for the hydrophobized powder of component (C) is preferably one or more selected from zinc oxide, titanium oxide, cerium oxide, iron oxide, and chromium oxide. <1> to <10> The oil-in-water emulsion composition according to any one of the above.

<12> The average particle size of the powder used for the hydrophobized powder of component (C) is preferably 0.01 μm or more, more preferably 0.012 μm or more, still more preferably 0.015 μm or more, and preferably 28 μm or less. The oil-in-water emulsion composition according to any one of <1> to <11>, which is more preferably 23 μm or less, and still more preferably 18 μm or less.

<13> Hydrophobizing treatment to powder, preferably fluorine compound treatment, silicone treatment, silicone resin treatment, pendant treatment, silane coupling agent treatment, titanate coupling agent treatment, oil agent treatment, acylamino acid metal salt treatment, poly One or more selected from acrylic acid treatment, metal soap treatment, crystalline cellulose treatment, inorganic compound treatment, plasma treatment, mechanochemical treatment, silane compound treatment, and silazane compound treatment, more preferably, silicone or silicone resin is used. Hydrophobic treatment using methylhydrogenpolysiloxane or methylhydrogenpolysiloxane / dimethylpolysiloxane copolymer represented by the following general formula (1), hydrophobization using silane compound or silazane compound Treatment, using titanate coupling agent One or more selected from hydrophobic treatment and hydrophobic treatment using acylamino acid metal salt, more preferably hydrophobic treatment using methylhydrogenpolysiloxane, hydrophobization using silane compound or silazane compound Any one of <1> to <12> selected from a treatment, a hydrophobic treatment using a titanate coupling agent, and a hydrophobic treatment using an acylamino acid metal salt An oil-in-water emulsion composition.

<14> The coating amount of the hydrophobizing agent on the powder is preferably 1% by mass or more, more preferably 1.5% by mass or more, and preferably 10% by mass or less, based on the total amount of powder used. The oil-in-water emulsion composition according to any one of <1> to <13>, which is preferably 5% by mass or less.

<15> The content of the component (C) is preferably 0.1% by mass or more, more preferably 1% by mass or more, still more preferably 5% by mass or more, and preferably 30% by mass or less, more preferably 20%. The oil-in-water emulsion composition according to any one of <1> to <14>, which is not more than mass%, more preferably not more than 15 mass%.

<16> The water content is preferably 40% by mass or more, more preferably 45% by mass or more, and preferably 80% by mass or less, more preferably 75% by mass or less. <1> to <15> The oil-in-water emulsion composition according to any one of the above.

<17> Preferably, the oil-in-water emulsion composition according to any one of <1> to <16>, further comprising a liquid oil as the component (E).

<18> The oil-in-water emulsion composition according to <17>, wherein the liquid oil of component (E) is an oil agent having fluidity at 25 ° C., preferably under 1013.25 hPa.

<19> Component (E) is a liquid oil containing one or more selected from 2-ethylhexyl paramethoxycinnamate, 2-ethylhexyl salicylate, homomenthyl salicylate, octocrylene and dimethicodiethylbenzalmalonate The oil-in-water emulsion composition according to <17> or <18>.

<20> The content of component (E) is preferably 5% by mass or more, more preferably 8% by mass or more, still more preferably 10% by mass or more, and preferably 25% by mass or less, more preferably 20% or less. The oil-in-water emulsion composition according to any one of <17> to <19>, which is not more than mass%, more preferably not more than 18 mass%.

<21> The mass ratio of the liquid organic ultraviolet absorber in the total component (E) is preferably 0.3 or more, more preferably 0.5 or more, still more preferably 0.6 or more, and even more preferably 0.7 or more <17> to The oil-in-water emulsion composition according to any one of <20>.

<22> Preferably, the oil-in-water emulsion composition according to any one of <1> to <21>, further comprising an ultraviolet absorbent that is solid at 25 ° C. as component (F).

<23> The content of the component (F) is preferably 0.5% by mass or more, more preferably 1% by mass or more, still more preferably 1.5% by mass or more, and preferably 10% by mass or less, more preferably 7.5%. The oil-in-water emulsion composition according to any one of <1> to <22>, which is not more than mass%, more preferably not more than 5 mass%.

<24> The oil-in-water emulsion composition according to any one of <1> to <23>, preferably further containing a water-soluble polymer as component (G).

<25> Component (G) is preferably carboxyvinyl polymer, acrylic acid / alkyl methacrylate copolymer, xanthan gum, hydroxypropyl methylcellulose, polyacrylamide, (Na acrylate / acryloyl dimethyl taurine Na) copolymer, (acryloyl dimethyl taurine) Ammonium / VP) copolymer and one or more selected from hyaluronic acid or alkali metal salts thereof, more preferably polyacrylamide, (Na acrylate / acryloyl dimethyl taurine Na) copolymer, (acryloyl dimethyl taurate ammonium / <VP> The oil-in-water emulsion composition according to <24>, comprising at least one selected from copolymers and xanthan gum.

<26> The content of component (G) is preferably 0.01% by mass or more, more preferably 0.05% by mass or more, still more preferably 0.1% by mass or more, and preferably 4% by mass or less, more preferably 2% by mass. % Or less, More preferably, it is 1.5 mass% or less, The oil-in-water emulsion composition as described in <24> or <25>.

<27> The oil-in-water emulsion composition according to any one of <1> to <26>, further comprising a saturated monohydric alcohol having 1 to 3 carbon atoms as component (H).

<28> The content of component (H) is preferably 1% by mass or more, more preferably 3% by mass or more, still more preferably 5% by mass or more, and preferably 20% by mass or less, more preferably 15% by mass. % Or less, more preferably 12% by mass or less, The oil-in-water emulsion composition according to <27>.

<29> The oil-in-water emulsion composition according to any one of <1> to <28>, further containing a polyhydric alcohol as component (I).

<30> Polyhydric alcohol in which component (I) preferably contains one or more selected from ethylene glycol, diethylene glycol, propylene glycol, dipropylene glycol, 1,3-butylene glycol, glycerin and diglycerin More preferably, the oil-in-water emulsion composition according to <29>, which is a polyhydric alcohol containing one or more selected from propylene glycol, dipropylene glycol, 1,3-butylene glycol and glycerin .

<31> The content of component (I) is preferably 0.1% by mass or more, more preferably 0.5% by mass or more, still more preferably 1% by mass or more, and preferably 12% by mass or less, more preferably 8% by mass. % Or less, more preferably 5% by mass or less, and still more preferably 3% by mass or less, <29> or <30>.

<32> The average emulsion particle size of the oil-in-water emulsion composition is preferably 1 μm or more, preferably 30 μm or less, more preferably 25 μm or less, and even more preferably 20 μm or less, any one of <1> to <31> 2. The oil-in-water emulsion composition according to item 1.

<33> Use of the oil-in-water emulsion composition according to any one of <1> to <32> as a skin external preparation.

Examples 1 to 13 and Comparative Examples 1 to 11
Oil-in-water emulsion compositions were prepared according to the formulations shown in Tables 1-5.
(Production method)
Step a: Components 1 to 9 and components 16 to 20 are uniformly mixed, heated to 80 ° C. and dissolved.
Step b: Disperse components 10 to 15 uniformly.
Step c: The step b preparation is added to the step a preparation, mixed uniformly, heated to 80 ° C. and dispersed.
Step d: Ingredients 21 to 30 are heated and dissolved at 40 ° C., naturally cooled to 25 ° C. and then uniformly mixed.
Step e: While stirring the preparation of Step d, add the preparation of Step c, and uniformly stir and mix with a homomixer.

The component (C) used in the examples will be described below.
-ASI-treated titanium oxide (manufactured by Daito Kasei)
Titanium oxide (substantially spherical, average particle size 0.2 μm) 98% by mass coated with 1.5% by mass of isopropyltriisostearoyl titanate, 0.42% by mass of sodium lauroyl aspartate, and 0.08% by mass of zinc chloride.

・ ASI-treated iron oxide (manufactured by Daito Kasei)
Iron oxide (needle, average particle size (length) 0.9μm, average width 0.08μm) 98% by mass, isopropyl triisostearoyl titanate 1.5% by mass, sodium lauroyl aspartate 0.42% by mass, zinc chloride 0.08% by mass Coated.

・ ASI processing talc (manufactured by Daito Kasei)
98% by mass of talc (plate, average particle size 15μm, average thickness 0.25μm) coated with 1.5% by mass of isopropyl triisostearoyl titanate, 0.42% by mass of sodium lauroyl aspartate, 0.08% by mass of zinc chloride .

・ OTS-treated titanium oxide A slurry consisting of 97 parts by mass of titanium oxide powder (substantially spherical, average particle size 0.2 μm), 3 parts by mass of octyltriethoxysilane, and toluene was prepared, and a bead mill (Dynomill manufactured by Shinmaru Enterprises Co., Ltd.) was used. Using this, pulverization and crushing were performed. Subsequently, toluene was distilled off by heating under reduced pressure, and then heat-treated at 150 ° C. for 4 hours using a blast airflow dryer to obtain octyltriethoxysilane-treated titanium oxide powder.

-OTS-treated flaky zinc oxide flaky zinc oxide particles (average particle size 0.3μm, average particle thickness 0.032μm, plate ratio 9, iron element content 0.01 mol%) 97 parts by mass and octyltriethoxysilane 3 parts by mass Then, a slurry made of toluene was prepared and pulverized and crushed using a bead mill (Dynomill manufactured by Shinmaru Enterprises Co., Ltd.). Subsequently, toluene was distilled off by heating under reduced pressure, followed by heat treatment at 150 ° C. for 4 hours using an air blast dryer to obtain octyltriethoxysilane-treated flaky zinc oxide powder.

・ OTS treated iron oxide Iron oxide powder (needle, average particle size (length) 0.9μm, average width 0.08μm) 97 parts by mass, octyltriethoxysilane 3 parts by mass, and a slurry made of toluene, bead mill ( Crushing and crushing were performed using a Shinmaru Enterprises Dynomill). Subsequently, toluene was distilled off by heating under reduced pressure, followed by heat treatment at 150 ° C. for 4 hours using an air blast dryer to obtain octyltriethoxysilane-treated fine particle iron oxide powder.

・ SI-treated zinc oxide A slurry consisting of 97 parts by mass of fine zinc oxide powder (substantially spherical, average particle size 0.017 μm), 3 parts by mass of methyl hydrogen polysiloxane (KF-99P, manufactured by Shin-Etsu Chemical Co., Ltd.) and isopropyl alcohol is prepared. After thoroughly stirring and pulverizing, the solvent was removed by heating under reduced pressure, and heat treatment was performed in air at 160 ° C. for 4 hours to obtain methylhydrogenpolysiloxane surface-treated fine particle zinc oxide powder.

The oil-in-water emulsion compositions (samples) shown in Tables 1 to 5 were subjected to various evaluations according to the following methods and standards, and the results are also shown in Tables 1 to 5.

[Emulsification stability (high temperature stability) evaluation]
Samples were placed in glass bottles, and each sample was stored in a constant temperature bath at 60 ° C. for 1 month. Based on the state immediately after production, the appearance change after one month was judged based on the following criteria by visual observation and microscopic observation (measurement magnification: 100 times).

(Criteria)
A: Appearance change is not recognized in any of observation by visual observation and observation by a microscope.
B: Appearance change was not recognized by visual observation, but coalescence of emulsified particles was observed as a whole by microscopic observation.
X: Appearance change (separation, creaming, etc.) was observed by visual observation.

[Shear resistance evaluation]
Using a rheometer (Physica MCR301; manufactured by Anton Paar), the sample was sheared under the following conditions, and the following viscosity change rate was measured. In addition, the sample was observed with a microscope (measurement magnification: 100 times) before and after applying shear, and the appearance was also observed. From these results, evaluation was performed based on the following criteria.

Measurement conditions: steady flow measurement mode, shear rate: 17 (1 / s), plate: PP25, measurement time: 300 seconds (measurement interval 15 seconds), measurement temperature 25 ° C

Viscosity change rate = (shear viscosity at the start of measurement 300 seconds) / (shear viscosity at the start of measurement 15 seconds)

(Criteria)
A: The viscosity change rate is 0.8 or more, and coalescence of emulsified particles is not observed by observation with a microscope.
B: Viscosity change rate was 0.8 or more, and coalescence of emulsified particles was observed by microscopic observation.
X: Viscosity change rate is less than 0.8

[Usage evaluation (sensory evaluation)]
The evaluation was performed by the number of respondents who asked 10 professional panelists to use samples and felt fresh after application.

[UV protection evaluation]
The sample was uniformly coated on a PMMA plate at a coating amount of 1.3 mg / cm ² and dried. Then, using SPF analyzer (UV-2000S; manufactured by Labsphere), SPF value was measured (in vitro) and evaluated based on the following evaluation criteria.

(Evaluation criteria)
A: SPF value is 40 or more B: SPF value is 30 or more and less than 40 C: SPF value is 20 or more and less than 30 X: SPF value is less than 20

* 1: Nikkor BB-2, manufactured by Nippon Surfactant
* 2: Nikkor BB-5, manufactured by Nippon Surfactant
* 3: Nikkor BC-2, manufactured by Nippon Surfactant
* 4: Nikkor BS-2, manufactured by Nippon Surfactant
* 5: Nikkor BL-2 manufactured by Nippon Surfactant
* 6: Phospholipid PCSH70, manufactured by Nippon Seika Co., Ltd., phosphatidylcholine content 70% by mass or more
* 7: COATSOME NC-21, NOF Corporation, phosphatidylcholine content 90% by mass or more
* 8: Sphingolipid E, manufactured by Kao Corporation
* 9: Yubinar T-150, manufactured by BASF
* 10: Yubinar A PLUS GURANULAR, manufactured by BASF
* 11: Yubinar MC80, manufactured by BASF
* 12: Saracos 913, manufactured by Nisshin Oillio Group
* 13: Silicone FK96-6cs, manufactured by Shin-Etsu Chemical Co., Ltd.
* 14: SIMULGEL EG (Pure value), manufactured by SEPPIC
* 15: Echo Gum, DSP Gokyo Food & Chemical

Hereafter, the prescription example of this invention is shown. Both have the same effects as the embodiment.

Formulation example 1 (oil-in-water makeup base)
Content (mass%)
Behenez-2 (* 1) 1.0
Hydrogenated lecithin (* 6) 1.0
ASI-treated titanium oxide 10.5
ASI-treated iron oxide 1.05
ASI processing talc 0.8
2-Ethylhexyl paramethoxycinnamate (* 11) 5.0
2- (4-Diethylamino-2-hydroxybenzoyl) benzoic acid hexyl ester (* 10)
2.0
2,4-Bis [[4- (2-ethylhexyloxy) -2-hydroxy] -phenyl] -6- (4-methoxyphenyl) -1,3,5-triazine (* 16) 0.5
2,4,6-Tris [4- (2-ethylhexyloxycarbonyl) anilino] -1,3,5-triazine (* 9) 2.0
Isononyl isononanoate (* 12) 3.0
Diisopropyl sebacate 2.0
Dimethicone (* 13) 0.5
EDTA-2Na 0.02
Glycerin 0.5
Ethanol 10.0
Seaweed extract (* 17) 0.1
Hydrolyzed collagen (* 18) 0.1
Royal Jelly Extract (* 19) 0.1
Pearl seed extract (* 20) 0.1
(Na acrylate / acryloyl dimethyl taurine Na) copolymer (* 14)
0.86
1,3-butylene glycol 1.0
Hyaluronic acid Na (* 21) 0.01
Xanthan gum (* 15) 0.1
Isohexadecane 0.52
Polysorbate 80 0.17
Sorbitan oleate 0.06
Purified water remaining

* 16: Made by BASF: Chinosorb S
* 17: Maruzen Pharmaceutical Co., Ltd .: Seaweed Extract M
* 18: Seiwa Kasei Co., Ltd .: Promois WU-32R
* 19: Made by Ichimaru Falcos: Royal Jelly Extract
* 20: Made by Maruzen Pharmaceutical Co., Ltd .: Yokuinin extract BG-S
* 21: Kikkoman Biochemifa Corporation: Hyaluronic acid FCH-SU

Formulation example 2 (oil-in-water sunscreen)
Content (mass%)
Behenez-2 (* 1) 0.5
Hydrogenated lecithin (* 6) 1.5
OTS-treated flaky zinc oxide 2.5
SI-treated zinc oxide 7.5
Polysilicone-15 (* 22) 1.0
2- (4-Diethylamino-2-hydroxybenzoyl) benzoic acid hexyl ester (* 10) 1.5
2,4-Bis [[4- (2-ethylhexyloxy) -2-hydroxy] -phenyl] -6- (4-methoxyphenyl) -1,3,5-triazine (* 16) 1.5
2,4,6-Tris [4- (2-ethylhexyloxycarbonyl) anilino] -1,3,5-triazine (* 9) 2.0
Neopentyl glycol dicaprate 2.5
Diisopropyl sebacate 5.0
Alkyl benzoate (C12-15) 2.5
Dimethicone (* 13) 1.0
Stearyl glycyrrhetinate (* 23) 0.1
EDTA-2Na 0.02
Glycerin 3.0
DPG 2.0
Ethanol 5.0
Phenoxyethanol 0.3
Chlorphenesin 0.2
Hypericum flower / leaf / stem extract (* 24) 0.1
Olive leaf extract (* 25) 0.1
(Na acrylate / acryloyl dimethyl taurine Na) copolymer (* 14)
0.83
Isohexadecane 0.5
Polysorbate 80 0.17
Sorbitan oleate 0.06
1,3-butylene glycol 2.0
Xanthan gum (* 15) 0.1
Purified water remaining

* 22: DSM Nutritional Products: Pulsol SLX
* 23: Maruzen Pharmaceutical Co., Ltd .: Sea Augretinol
* 24: Made by Ichimaru Falcos: Falco Rex Hypericum B
* 25: Maruzen Pharmaceutical Co., Ltd .: Olive leaf extract BG

Claims

An oil-in-water emulsion composition comprising the following components (A) to (D), wherein the mass ratio [(A) / (B)] of component (A) to component (B) is 0.06 or more and 18 or less.
(A) Polyoxyethylene alkyl ether or polyoxyethylene alkenyl ether having an alkyl group or alkenyl group having 20 to 24 carbon atoms and an average addition mole number of ethylene oxide of 1.5 to 4 (B) Phospholipid (C ) Hydrophobized powder (D) Water
The oil-in-water emulsion composition according to claim 1, wherein the total content of the component (A) and the component (B) is from 0.5% by mass to 6% by mass.
Furthermore, the oil-in-water emulsion composition according to claim 1 or 2, further comprising liquid oil as component (E).
The component (E) is a liquid oil containing one or more selected from 2-ethylhexyl paramethoxycinnamate, 2-ethylhexyl salicylate, homomenthyl salicylate, octocrylene, and dimethicodiethylbenzalmalonate. Item 4. The oil-in-water emulsion composition according to Item 3.
The oil-in-water emulsion composition according to any one of claims 1 to 4, further comprising an ultraviolet absorber that is solid at 25 ° C as component (F).
Use of the oil-in-water emulsion composition according to any one of claims 1 to 5 as a skin external preparation.